Genetic association of COL5A1 variants in keratoconus patients suggests a complex connection between corneal thinning and keratoconus

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 4, 2013, Pages 2696-2704

  Li, Xiaohui ^a   Bykhovskaya, Yelena ^a   Canedo, Ana Laura Caiado ^a   Haritunians, Talin ^a   Siscovick, David ^b   Aldave, Anthony J ^c   Szczotka Flynn, Loretta ^d   Iyengar, Sudha K ^d   Rotter, Jerome I ^a   Taylor, Kent D ^a   Rabinowitz, Yaron S ^a,c  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c JULES STEIN EYE INSTITUTE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Association; COL5A1; Keratoconus

Indexed keywords

COLLAGEN TYPE 5; COLLAGEN TYPE 5 ALPHA 1; CYCLOPENTOLATE; PHENYLEPHRINE; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; CASE CONTROL STUDY; CENTRAL CORNEAL THICKNESS; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA EXTRACTION; FAMILY; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; HUMAN; KERATOCONUS; MAJOR CLINICAL STUDY; MALE; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RETINOSCOPY; SINGLE NUCLEOTIDE POLYMORPHISM; SLIT LAMP;

ADULT; AGED; COLLAGEN TYPE V; CORNEA; CORNEAL TOPOGRAPHY; DNA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; KERATOCONUS; MALE; MICROSCOPY, ACOUSTIC; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84876088333     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-11601     Document Type: Article

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