메뉴 건너뛰기




Volumn 129, Issue 3, 2013, Pages 254-264

NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent

Author keywords

Alcohol dependence; EQTL; Genome wide association studies; Replication; Risk region

Indexed keywords

BIOLOGICAL MARKER; CIS ACTING ELEMENT;

EID: 84876085365     PISSN: 03768716     EISSN: 18790046     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2013.02.006     Document Type: Article
Times cited : (29)

References (66)
  • 1
    • 0004235298 scopus 로고
    • American Psychiatric Association, American Psychiatric Press, Washington, DC
    • American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 1994, American Psychiatric Press, Washington, DC.
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 5
    • 79551567029 scopus 로고    scopus 로고
    • The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women
    • Chen X., Cho K., Singer B.H., Zhang H. The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women. PLoS ONE 2011, 6:e16002.
    • (2011) PLoS ONE , vol.6
    • Chen, X.1    Cho, K.2    Singer, B.H.3    Zhang, H.4
  • 6
    • 0019466547 scopus 로고
    • Inheritance of alcohol abuse. Cross-fostering analysis of adopted men
    • Cloninger C.R., Bohman M., Sigvardsson S. Inheritance of alcohol abuse. Cross-fostering analysis of adopted men. Arch. Gen. Psychiatr. 1981, 38:861-868.
    • (1981) Arch. Gen. Psychiatr. , vol.38 , pp. 861-868
    • Cloninger, C.R.1    Bohman, M.2    Sigvardsson, S.3
  • 7
    • 15744397577 scopus 로고    scopus 로고
    • Tyrosine hydroxylase Val-81-Met polymorphism associated with early-onset alcoholism
    • Dahmen N., Volp M., Singer P., Hiemke C., Szegedi A. Tyrosine hydroxylase Val-81-Met polymorphism associated with early-onset alcoholism. Psychiatr. Genet. 2005, 15:13-16.
    • (2005) Psychiatr. Genet. , vol.15 , pp. 13-16
    • Dahmen, N.1    Volp, M.2    Singer, P.3    Hiemke, C.4    Szegedi, A.5
  • 8
    • 35848930802 scopus 로고    scopus 로고
    • Maternal alcohol consumption increases sphingosine levels in the brains of progeny mice
    • Dasgupta S., Adams J.A., Hogan E.L. Maternal alcohol consumption increases sphingosine levels in the brains of progeny mice. Neurochem. Res. 2007, 32:2217-2224.
    • (2007) Neurochem. Res. , vol.32 , pp. 2217-2224
    • Dasgupta, S.1    Adams, J.A.2    Hogan, E.L.3
  • 9
    • 0038324103 scopus 로고    scopus 로고
    • Candidate genes for alcohol dependence: a review of genetic evidence from human studies
    • Dick D.M., Foroud T. Candidate genes for alcohol dependence: a review of genetic evidence from human studies. Alcohol. Clin. Exp. Res. 2003, 27:868-879.
    • (2003) Alcohol. Clin. Exp. Res. , vol.27 , pp. 868-879
    • Dick, D.M.1    Foroud, T.2
  • 14
    • 67651119880 scopus 로고    scopus 로고
    • Genetics of alcohol dependence
    • Gelernter J., Kranzler H.R. Genetics of alcohol dependence. Hum. Genet. 2009, 126:91-99.
    • (2009) Hum. Genet. , vol.126 , pp. 91-99
    • Gelernter, J.1    Kranzler, H.R.2
  • 15
    • 33845364418 scopus 로고    scopus 로고
    • Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations
    • Gelernter J., Yu Y., Weiss R., Brady K., Panhuysen C., Yang B.Z., Kranzler H.R., Farrer L. Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations. Hum. Mol. Genet. 2006, 15:3498-3507.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 3498-3507
    • Gelernter, J.1    Yu, Y.2    Weiss, R.3    Brady, K.4    Panhuysen, C.5    Yang, B.Z.6    Kranzler, H.R.7    Farrer, L.8
  • 16
    • 3543055314 scopus 로고    scopus 로고
    • Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    • Grant B.F., Stinson F.S., Dawson D.A., Chou S.P., Dufour M.C., Compton W., Pickering R.P., Kaplan K. Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch. Gen. Psychiatr. 2004, 61:807-816.
    • (2004) Arch. Gen. Psychiatr. , vol.61 , pp. 807-816
    • Grant, B.F.1    Stinson, F.S.2    Dawson, D.A.3    Chou, S.P.4    Dufour, M.C.5    Compton, W.6    Pickering, R.P.7    Kaplan, K.8
  • 17
    • 0034090608 scopus 로고    scopus 로고
    • Identification of a ubiquitous family of membrane proteins and their expression in mouse brain
    • Grossman T.R., Luque J.M., Nelson N. Identification of a ubiquitous family of membrane proteins and their expression in mouse brain. J. Exp. Biol. 2000, 203:447-457.
    • (2000) J. Exp. Biol. , vol.203 , pp. 447-457
    • Grossman, T.R.1    Luque, J.M.2    Nelson, N.3
  • 18
    • 1842557804 scopus 로고    scopus 로고
    • Lipid rafts mediate chemotropic guidance of nerve growth cones
    • Guirland C., Suzuki S., Kojima M., Lu B., Zheng J.Q. Lipid rafts mediate chemotropic guidance of nerve growth cones. Neuron 2004, 42:51-62.
    • (2004) Neuron , vol.42 , pp. 51-62
    • Guirland, C.1    Suzuki, S.2    Kojima, M.3    Lu, B.4    Zheng, J.Q.5
  • 22
    • 0035055544 scopus 로고    scopus 로고
    • The family based association test method: strategies for studying general genotype-phenotype associations
    • Horvath S., Xu X., Laird N.M. The family based association test method: strategies for studying general genotype-phenotype associations. Eur. J. Hum. Genet. 2001, 9:301-306.
    • (2001) Eur. J. Hum. Genet. , vol.9 , pp. 301-306
    • Horvath, S.1    Xu, X.2    Laird, N.M.3
  • 23
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie B.N., Donnelly P., Marchini J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 2009, 5:e1000529.
    • (2009) PLoS Genet. , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 24
    • 55349107598 scopus 로고    scopus 로고
    • A functional polymorphism, rs6280, in DRD3 is significantly associated with nicotine dependence in European-American smokers
    • Huang W., Payne T.J., Ma J.Z., Li M.D. A functional polymorphism, rs6280, in DRD3 is significantly associated with nicotine dependence in European-American smokers. Am. J. Med. Genet. B: Neuropsychiatr. Genet. 2008, 147B:1109-1115.
    • (2008) Am. J. Med. Genet. B: Neuropsychiatr. Genet. , vol.147 B , pp. 1109-1115
    • Huang, W.1    Payne, T.J.2    Ma, J.Z.3    Li, M.D.4
  • 26
    • 27444448059 scopus 로고    scopus 로고
    • Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis
    • Inuzuka M., Hayakawa M., Ingi T. Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis. J. Biol. Chem. 2005, 280:35776-35783.
    • (2005) J. Biol. Chem. , vol.280 , pp. 35776-35783
    • Inuzuka, M.1    Hayakawa, M.2    Ingi, T.3
  • 29
    • 14644397886 scopus 로고    scopus 로고
    • Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice
    • Kerns R.T., Ravindranathan A., Hassan S., Cage M.P., York T., Sikela J.M., Williams R.W., Miles M.F. Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. J. Neurosci. 2005, 25:2255-2266.
    • (2005) J. Neurosci. , vol.25 , pp. 2255-2266
    • Kerns, R.T.1    Ravindranathan, A.2    Hassan, S.3    Cage, M.P.4    York, T.5    Sikela, J.M.6    Williams, R.W.7    Miles, M.F.8
  • 30
    • 0030033969 scopus 로고    scopus 로고
    • The epidemiology of co-occurring addictive and mental disorders: implications for prevention and service utilization
    • Kessler R.C., Nelson C.B., McGonagle K.A., Edlund M.J., Frank R.G., Leaf P.J. The epidemiology of co-occurring addictive and mental disorders: implications for prevention and service utilization. Am. J. Orthopsychiatr. 1996, 66:17-31.
    • (1996) Am. J. Orthopsychiatr. , vol.66 , pp. 17-31
    • Kessler, R.C.1    Nelson, C.B.2    McGonagle, K.A.3    Edlund, M.J.4    Frank, R.G.5    Leaf, P.J.6
  • 32
    • 0037526206 scopus 로고    scopus 로고
    • N-methyl-d-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability
    • Krystal J.H., Petrakis I.L., Mason G., Trevisan L., D'Souza D.C. N-methyl-d-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. Pharmacol. Ther. 2003, 99:79-94.
    • (2003) Pharmacol. Ther. , vol.99 , pp. 79-94
    • Krystal, J.H.1    Petrakis, I.L.2    Mason, G.3    Trevisan, L.4    D'Souza, D.C.5
  • 34
    • 30744434862 scopus 로고    scopus 로고
    • Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
    • Li J., Ji L. Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity (Edinburgh) 2005, 95:221-227.
    • (2005) Heredity (Edinburgh) , vol.95 , pp. 221-227
    • Li, J.1    Ji, L.2
  • 35
    • 67649198995 scopus 로고    scopus 로고
    • Association between harmful alcohol consumption behavior and dopamine transporter (DAT1) gene polymorphisms in a male Finnish population
    • Lind P.A., Eriksson C.J., Wilhelmsen K.C. Association between harmful alcohol consumption behavior and dopamine transporter (DAT1) gene polymorphisms in a male Finnish population. Psychiatr. Genet. 2009, 19:117-125.
    • (2009) Psychiatr. Genet. , vol.19 , pp. 117-125
    • Lind, P.A.1    Eriksson, C.J.2    Wilhelmsen, K.C.3
  • 36
    • 0041821758 scopus 로고    scopus 로고
    • Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans
    • Luo X., Kranzler H.R., Zhao H., Gelernter J. Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans. Am. J. Med. Genet. B: Neuropsychiatr. Genet. 2003, 120B:97-108.
    • (2003) Am. J. Med. Genet. B: Neuropsychiatr. Genet. , vol.120 B , pp. 97-108
    • Luo, X.1    Kranzler, H.R.2    Zhao, H.3    Gelernter, J.4
  • 37
    • 33646157292 scopus 로고    scopus 로고
    • ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies
    • Luo X., Kranzler H.R., Zuo L., Lappalainen J., Yang B.Z., Gelernter J. ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies. Neuropsychopharmacology 2006, 31:1085-1095.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1085-1095
    • Luo, X.1    Kranzler, H.R.2    Zuo, L.3    Lappalainen, J.4    Yang, B.Z.5    Gelernter, J.6
  • 38
    • 33646891714 scopus 로고    scopus 로고
    • Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence
    • Luo X., Kranzler H.R., Zuo L., Wang S., Schork N.J., Gelernter J. Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. Am. J. Hum. Genet. 2006, 78:973-987.
    • (2006) Am. J. Hum. Genet. , vol.78 , pp. 973-987
    • Luo, X.1    Kranzler, H.R.2    Zuo, L.3    Wang, S.4    Schork, N.J.5    Gelernter, J.6
  • 39
    • 77649183574 scopus 로고    scopus 로고
    • The serotonin transporter gene and risk for alcohol dependence: a meta-analytic review
    • McHugh R.K., Hofmann S.G., Asnaani A., Sawyer A.T., Otto M.W. The serotonin transporter gene and risk for alcohol dependence: a meta-analytic review. Drug Alcohol Depend. 2010, 108:1-6.
    • (2010) Drug Alcohol Depend. , vol.108 , pp. 1-6
    • McHugh, R.K.1    Hofmann, S.G.2    Asnaani, A.3    Sawyer, A.T.4    Otto, M.W.5
  • 41
    • 0027183404 scopus 로고
    • Numerous candidate plasticity-related genes revealed by differential cDNA cloning
    • Nedivi E., Hevroni D., Naot D., Israeli D., Citri Y. Numerous candidate plasticity-related genes revealed by differential cDNA cloning. Nature 1993, 363:718-722.
    • (1993) Nature , vol.363 , pp. 718-722
    • Nedivi, E.1    Hevroni, D.2    Naot, D.3    Israeli, D.4    Citri, Y.5
  • 42
    • 0028038057 scopus 로고
    • Requirement of a critical period of transcription for induction of a late phase of LTP
    • Nguyen P.V., Abel T., Kandel E.R. Requirement of a critical period of transcription for induction of a late phase of LTP. Science 1994, 265:1104-1107.
    • (1994) Science , vol.265 , pp. 1104-1107
    • Nguyen, P.V.1    Abel, T.2    Kandel, E.R.3
  • 43
    • 0942279610 scopus 로고    scopus 로고
    • Association between dependent smoking and a polymorphism in the tyrosine hydroxylase gene in a prospective population-based study of adolescent health
    • Olsson C., Anney R., Forrest S., Patton G., Coffey C., Cameron T., Hassett A., Williamson R. Association between dependent smoking and a polymorphism in the tyrosine hydroxylase gene in a prospective population-based study of adolescent health. Behav. Genet. 2004, 34:85-91.
    • (2004) Behav. Genet. , vol.34 , pp. 85-91
    • Olsson, C.1    Anney, R.2    Forrest, S.3    Patton, G.4    Coffey, C.5    Cameron, T.6    Hassett, A.7    Williamson, R.8
  • 44
    • 15944394377 scopus 로고    scopus 로고
    • Thr105Ile, a functional polymorphism of histamine N-methyltransferase, is associated with alcoholism in two independent populations
    • Oroszi G., Enoch M.A., Chun J., Virkkunen M., Goldman D. Thr105Ile, a functional polymorphism of histamine N-methyltransferase, is associated with alcoholism in two independent populations. Alcohol. Clin. Exp. Res. 2005, 29:303-309.
    • (2005) Alcohol. Clin. Exp. Res. , vol.29 , pp. 303-309
    • Oroszi, G.1    Enoch, M.A.2    Chun, J.3    Virkkunen, M.4    Goldman, D.5
  • 47
    • 0025226205 scopus 로고
    • Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study
    • Regier D.A., Farmer M.E., Rae D.S., Locke B.Z., Keith S.J., Judd L.L., Goodwin F.K. Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. J. Am. Med. Assoc. 1990, 264:2511-2518.
    • (1990) J. Am. Med. Assoc. , vol.264 , pp. 2511-2518
    • Regier, D.A.1    Farmer, M.E.2    Rae, D.S.3    Locke, B.Z.4    Keith, S.J.5    Judd, L.L.6    Goodwin, F.K.7
  • 52
    • 34248550908 scopus 로고    scopus 로고
    • Association between dopamine transporter genotypes and smoking cessation: a meta-analysis
    • Stapleton J.A., Sutherland G., O'Gara C. Association between dopamine transporter genotypes and smoking cessation: a meta-analysis. Addict. Biol. 2007, 12:221-226.
    • (2007) Addict. Biol. , vol.12 , pp. 221-226
    • Stapleton, J.A.1    Sutherland, G.2    O'Gara, C.3
  • 55
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls
    • The Wellcome Trust Case Control Consortium
    • The Wellcome Trust Case Control Consortium Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls. Nature 2007, 447:661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 59
    • 80053951313 scopus 로고    scopus 로고
    • A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence
    • Wang K.S., Liu X., Zhang Q., Pan Y., Aragam N., Zeng M. A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence. J. Psychiatr. Res. 2011, 45:1419-1425.
    • (2011) J. Psychiatr. Res. , vol.45 , pp. 1419-1425
    • Wang, K.S.1    Liu, X.2    Zhang, Q.3    Pan, Y.4    Aragam, N.5    Zeng, M.6
  • 61
    • 57249083992 scopus 로고    scopus 로고
    • Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence
    • Yang B.Z., Kranzler H.R., Zhao H., Gruen J.R., Luo X., Gelernter J. Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence. Alcohol. Clin. Exp. Res. 2008, 32:2117-2127.
    • (2008) Alcohol. Clin. Exp. Res. , vol.32 , pp. 2117-2127
    • Yang, B.Z.1    Kranzler, H.R.2    Zhao, H.3    Gruen, J.R.4    Luo, X.5    Gelernter, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.