High Expression of KIF26B in Breast Cancer Associates with Poor Prognosis

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Wang, Qun ^a   Zhao, Zong Bin ^a   Wang, Geng ^a   Hui, Zhen ^a   Wang, Ming Hua ^a   Pan, Jun Feng ^a   Zheng, Hong ^a  

^a Taihe Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; KINESIN; KINESIN FAMILY MEMBER 26B; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BREAST CANCER; CANCER GRADING; CANCER PROGNOSIS; CANCER SPECIFIC SURVIVAL; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; FEMALE; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL PREDICTION; TUMOR VOLUME; WESTERN BLOTTING;

AGED; BREAST NEOPLASMS; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION; HUMANS; KAPLAN-MEIER ESTIMATE; KINESIN; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM GRADING; PROGNOSIS; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 84876016429     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061640     Document Type: Article

References (29)

1. Siegel R, Naishadham D, Jemal A, (2012) Cancer statistics, 2012. CA Cancer J Clin 62: 10-29.
2. Parker JS, Mullins M, Cheang MC, Leung S, Voduc D, et al. (2009) Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol 27: 1160-1167.
3. Zhu C, Zhao J, Bibikova M, Leverson JD, Bossy-Wetzel E, et al. (2005) Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference. Mol Biol Cell 16: 3187-3199.
4. Goldstein LS, Philp AV, (1999) The road less traveled: emerging principles of kinesin motor utilization. Annu Rev Cell Dev Biol 15: 141-183.
5. Hirokawa N, Noda Y, Tanaka Y, Niwa S, (2009) Kinesin superfamily motor proteins and intracellular transport. Nat Rev Mol Cell Biol 10: 682-696.
6. Miki H, Okada Y, Hirokawa N, (2005) Analysis of the kinesin superfamily: insights into structure and function. Trends Cell Biol 15: 467-476.
7. Miki H, Setou M, Kaneshiro K, Hirokawa N, (2001) All kinesin superfamily protein, KIF, genes in mouse and human. Proc Natl Acad Sci U S A 98: 7004-7011.
8. Yu Y, Feng YM, (2010) The role of kinesin family proteins in tumorigenesis and progression: potential biomarkers and molecular targets for cancer therapy. Cancer 116: 5150-5160.
9. Rath O, Kozielski F, (2012) Kinesins and cancer. Nat Rev Cancer 12: 527-539.
10. Huszar D, Theoclitou ME, Skolnik J, Herbst R, (2009) Kinesin motor proteins as targets for cancer therapy. Cancer Metastasis Rev 28: 197-208.
11. Marikawa Y, Fujita TC, Alarcon VB, (2004) An enhancer-trap LacZ transgene reveals a distinct expression pattern of Kinesin family 26B in mouse embryos. Dev Genes Evol 214: 64-71.
12. Lillie SH, Brown SS, (1998) Smy1p, a kinesin-related protein that does not require microtubules. J Cell Biol 140: 873-883.
13. Zhou R, Niwa S, Homma N, Takei Y, Hirokawa N, (2009) KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development. Cell 139: 802-813.
14. Nishinakamura R, Matsumoto Y, Nakao K, Nakamura K, Sato A, et al. (2001) Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Development 128: 3105-3115.
15. Liu L, Zhang CZ, Cai M, Fu J, Chen GG, et al. (2012) Downregulation of polo-like kinase 4 in hepatocellular carcinoma associates with poor prognosis. PLoS One 7: e41293.
16. Vale RD, Reese TS, Sheetz MP, (1985) Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell 42: 39-50.
17. Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, et al. (2004) A standardized kinesin nomenclature. J Cell Biol 167: 19-22.
18. Phelps MA, Foraker AB, Swaan PW, (2003) Cytoskeletal motors and cargo in membrane trafficking: opportunities for high specificity in drug intervention. Drug Discov Today 8: 494-502.
19. Sablin EP, (2000) Kinesins and microtubules: their structures and motor mechanisms. Curr Opin Cell Biol 12: 35-41.
20. Uchiyama Y, Sakaguchi M, Terabayashi T, Inenaga T, Inoue S, et al. (2010) Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme. Proc Natl Acad Sci U S A 107: 9240-9245.
21. Corson TW, Zhu CQ, Lau SK, Shepherd FA, Tsao MS, et al. (2007) KIF14 messenger RNA expression is independently prognostic for outcome in lung cancer. Clin Cancer Res 13: 3229-3234.
22. Zhang C, Zhu C, Chen H, Li L, Guo L, et al. (2010) Kif18A is involved in human breast carcinogenesis. Carcinogenesis 31: 1676-1684.
23. Taniwaki M, Takano A, Ishikawa N, Yasui W, Inai K, et al. (2007) Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer. Clin Cancer Res 13: 6624-6631.
24. Madhavan J, Coral K, Mallikarjuna K, Corson TW, Amit N, et al. (2007) High expression of KIF14 in retinoblastoma: association with older age at diagnosis. Invest Ophthalmol Vis Sci 48: 4901-4906.
25. Corson TW, Gallie BL, (2006) KIF14 mRNA expression is a predictor of grade and outcome in breast cancer. Int J Cancer 119: 1088-1094.
26. Corson TW, Huang A, Tsao MS, Gallie BL, (2005) KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers. Oncogene 24: 4741-4753.
27. Castillo A, Morse HC 3rd, Godfrey VL, Naeem R, Justice MJ, (2007) Overexpression of Eg5 causes genomic instability and tumor formation in mice. Cancer Res 67: 10138-10147.
28. Yamashita K, Sato A, Asashima M, Wang PC, Nishinakamura R, (2007) Mouse homolog of SALL1, a causative gene for Townes-Brocks syndrome, binds to A/T-rich sequences in pericentric heterochromatin via its C-terminal zinc finger domains. Genes Cells 12: 171-182.
29. Ma Y, Chai L, Cortez SC, Stopa EG, Steinhoff MM, et al. (2002) SALL1 expression in the human pituitary-adrenal/gonadal axis. J Endocrinol 173: 437-448.