The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells

Molecular Medicine Reports

Volumn 7, Issue 5, 2013, Pages 1539-1544

  Liao, Yu Ren ^a   Lu, Chi Cheng ^b   Lai, Kuang Chi ^c,d   Yang, Jai Sing ^e   Kuo, Sheng Chu ^e   Wen, Yen Fang ^f   Fushiya, Shinji ^g   Wu, Tian Shung ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

^f INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE   (Taiwan)

^g NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase; COLO 205 cells; Hep 3B cells; ITR 284

Indexed keywords

AMIDE; APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 8; CASPASE 9; ITR 284; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL STRUCTURE; CELL VIABILITY; COLORECTAL CANCER; COLORIMETRY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PHASE CONTRAST MICROSCOPY;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CASPASE INHIBITORS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; COLORECTAL NEOPLASMS; ENZYME ACTIVATION; HUMANS; LIVER NEOPLASMS; THIOPHENES;

EID: 84876005466     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1359     Document Type: Article

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