C. elegans PAR-3 and PAR-6 are required for apicobasal asymmetries associated with cell adhesion and gastrulation

Development

Volumn 130, Issue 22, 2003, Pages 5339-5350

  Nance, Jeremy ^a   Munro, Edwin M ^b   Priess, James R ^a,c  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Apicobasal; C. elegans; Cell adhesion; Gastrulation; Ingression; NMY 2; Nonmuscle myosin; PAR 3; PAR 6

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; HYBRID PROTEIN; MYOSIN; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 6; UNCLASSIFIED DRUG;

ANTERIOR POSTERIOR AXIS; APICAL MEMBRANE; ARTICLE; CAENORHABDITIS ELEGANS; CELL ADHESION; CELL CYCLE; CELL POLARITY; CELL SEPARATION; CELL SURFACE; CONTROLLED STUDY; EMBRYO; EMBRYO AXIS; EMBRYO CELL; EMBRYO DEVELOPMENT; GASTRULATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN TARGETING;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL ADHESION; GASTRULA; GENES, REPORTER; PROTEINS; TRANSGENES;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; INVERTEBRATA; NEMATODA; RICKETTSIA SP. PAR;

EID: 0344033629     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00735     Document Type: Article

References (50)

1. Bilder, D., Schober, M. and Perrimon, N. (2003). Integrated activity of PDZ protein complexes regulates epithelial polarity. Nat. Cell Biol. 5, 53-58.
2. Boyd, L., Guo, S., Levitan, D., Stinchcomb, D. T. and Kemphues, K. J. (1996). PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos. Development 122, 3075-3084.
3. Brenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94.
4. Cassata, G., Kagoshima, H., Prétôt, R. F., Aspöck, G., Niklaus, G. and Bürglin, T. R. (1998). Rapid expression screening of Caenorhabditis elegans homeobox open reading frames using a two-step polymerase chain reaction promoter-gfp reporter construction technique. Gene 212, 127-135.
5. Chen, L., Ong, B. and Bennett, V. (2001). LAD-1, the Caenorhabditis elegans L1CAM homologue, participates in embryonic and gonadal morphogenesis and is a substrate for fibroblast growth factor receptor pathway-dependent phosphotyrosine-based signaling. J. Cell Biol. 154, 841-855.
6. Cheng, N. N., Kirby, C. M. and Kemphues, K. J. (1995). Control of cleavage spindle orientation in Caenorhabditis elegans: the role of the genes par-2 and par-3. Genetics 139, 549-559.
7. Costa, M., Wilson, E. T. and Wieschaus, E. (1994). A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation. Cell 76, 1075-1089.
8. Costa, M., Draper, B. W. and Priess, J. R. (1997). The role of actin filaments in patterning the Caenorhabditis elegans cuticle. Dev. Biol. 184, 373-384.
9. Costa, M., Raich, W., Agbunag, C., Leung, B., Hardin, J. and Priess, J. R. (1998). A putative catenin-cadherin system mediates morphogenesis of the Caenorhabditis elegans embryo. J. Cell Biol. 141, 297-308.
10. Doe, C. Q. and Bowerman, B. (2001). Asymmetric cell division: fly neuroblast meets worm zygote. Curr. Opin. Cell Biol. 13, 68-75.
11. Etemad-Moghadam, B., Guo, S. and Kemphues, K. J. (1995). Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos. Cell 83, 743-752.
12. Guo, S. and Kemphues, K. J. (1995). par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81, 611-620.
13. Guo, S. and Kemphues, K. J. (1996). A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans. Nature 382, 455-458.
14. Higgs, H. N. and Pollard, T. D. (2001). Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins. Annu. Rev. Biochem. 70, 649-676.
15. Hodgkin, J. (1997). Genetics. In C. elegans II (ed. D. L. Riddle, T. Blumenthal, B. J. Meyer and J. R. Priess), pp. 881-1048. Plainview, NY: Cold Spring Harbor Laboratory Press.
16. Hodgkin, J., Horvitz, H. R. and Brenner, S. (1979). Nondisjunction mutants of the nematode C. elegans. Genetics 91, 67-94.
17. Hung, T. J. and Kemphues, K. J. (1999). PAR-6 is a conserved PDZ domain-containing protein that colocalizes with PAR-3 in Caenorhabditis elegans embryos. Development 126, 127-135.
18. Joberty, G., Petersen, C., Gao, L. and Macara, I. G. (2000). The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat. Cell Biol. 2, 531-539.
19. Kawasaki, I., Shim, Y. H., Kirchner, J., Kaminker, J., Wood, W. B. and Strome, S. (1998). PGL-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans. Cell 94, 635-645.
20. Kemphues, K. J., Priess, J. R., Morton, D. G. and Cheng, N. (1988). Identification of genes required for cytoplasmic localization in early C. elegans embryos. Cell 52, 311-320.
21. Kemphues, K. J. and Strome, S. (1997). Fertilization and establishment of polarity in the embryo. In C. elegans II (ed. D. L. Riddle, T. Blumenthal, B. J. Meyer and J. R. Priess), pp. 335-359. Plainview, NY: Cold Spring Harbor Laboratory Press.
22. Knust, E. and Bossinger, O. (2003). Composition and formation of intercellular junctions in epithelial cells. Science 298, 1955-1959.
23. Lee, J.-Y. and Goldstein, B. (2003). Mechanisms of cell positioning during C. elegans gastrulation. Development 130, 307-320.
24. Leptin, M. (1999). Gastrulation in Drosophila: the logic and the cellular mechanisms. EMBO J. 18, 3187-3192.
25. Leung, B., Hermann, G. J. and Priess, J. R. (1999). Organogenesis of the Caenorhabditis elegans intestine. Dev. Biol. 216, 114-134.
26. Lin, D., Edwards, A. S., Fawcett, J. P., Mbamalu, G., Scott, J. D. and Pawson, T. (2000). A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nat. Cell Biol. 2, 540-547.
27. Maduro, M. and Pilgrim, D. (1995). Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system. Genetics 141, 977-988.
28. Maduro, M. F. and Rothman, J. H. (2002). Making worm guts: the gene regulatory network of the Caenorhabditis elegans endoderm. Dev. Biol. 246, 68-85.
29. McMahon, L., Legouis, R., Vonesch, J. L. and Labouesse, M. (2001). Assembly of C. elegans apical junctions involves positioning and compaction by LET-413 and protein aggregation by the MAGUK protein DLG-1. J. Cell Sci. 114, 2265-2277.
30. Mello, C. and Fire, A. (1995). DNA transformation. In Caenorhabditis elegans: Modern Biological Analysis of an Organism. Vol. 48 (ed. H. F. Epstein and D. C. Shakes), pp. 451-482. San Diego: Academic Press.
31. Mello, C. C., Schubert, C., Draper, B., Zhang, W., Lobel, R. and Priess, J. R. (1996). The PIE-1 protein and germline specification in C. elegans embryos. Nature 382, 710-712.
32. Müller, H. -A. J. and Wieschaus, E. (1996). armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of polarized blastoderm epithelium in Drosophila. J. Cell Biol. 134, 149-163.
33. Nance, J. and Priess, J. R. (2002). Cell polarity and gastrulation in C. elegans. Development 129, 387-397.
34. Parks, S. and Wieschaus, E. (1991). The Drosophila gastrulation gene concertina encodes a Gα-like protein. Cell 64, 447-458.
35. Pellettieri, J. and Seydoux, G. (2002). Anterior-posterior polarity in C. elegans and Drosophila-PARallels and differences. Science 298, 1946-1950.
36. Petronczki, M. and Knoblich, J. A. (2001). DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila. Nat. Cell Biol. 3, 43-49.
37. Praitis, V., Casey, E., Collar, D. and Austin, J. (2001). Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics 157, 1217-1226.
38. Priess, J. R. and Hirsh, D. I. (1986). Caenorhabditis elegans morphogenesis: The role of the cytoskeleton in elongation of the embryo. Dev. Biol. 117, 150-173.
39. Reese, K. J., Dunn, M. A., Waddle, J. A. and Seydoux, G. (2000). Asymmetric segregation of PIE-1 in C. elegans is mediated by two complementary mechanisms that act through separate PIE-1 protein domains. Mol. Cell 6, 445-455.
40. Schnabel, R., Hutter, H., Moerman, D. and Schnabel, H. (1997). Assessing normal embryogenesis in Caenorhabditis elegans using a 4D microscope: variability of development and regional specification. Dev. Biol. 184, 234-265.
41. Severson, A. F., Baillie, D. L. and Bowerman, B. (2002). A formin homology protein and a profilin are required for cytokinesis and Arp2/3-independent assembly of cortical microfilaments in the early Caenorhabditis elegans embryo. Curr. Biol. 12, 2066-2075.
42. Sulston, J. E., Schierenberg, E., White, J. G. and Thomson, J. N. (1983). The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev. Biol. 100, 64-119.
43. Swanson, M. M. and Riddle, D. L. (1981). Critical periods in the development of the Caenorhabditis elegans dauer larva. Dev. Biol. 84, 27-40.
44. Tabuse, Y., Izumi, Y., Piano, F., Kemphues, K. J., Miwa, J. and Ohno, S. (1998). Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans. Development 125, 3607-3614.
45. Tanentzapf, G. and Tepass, U. (2003). Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization. Nat. Cell Biol. 5, 46-52.
46. Tenenhaus, C., Schubert, C. and Seydoux, G. (1998). Genetic requirements for PIE-1 localization and inhibition of gene expression in the embryonic germ lineage of Caenorhabditis elegans. Dev. Biol. 200, 212-224.
47. Watts, J. L., Etemad-Moghadam, B., Guo, S., Boyd, L., Draper, B. W., Mello, C. C., Priess, J. R. and Kemphues, K. J. (1996). par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3. Development 122, 3133-3140.
48. Wayner, E. A. and Carter, W. G. (1987). Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits. J. Cell Biol. 105, 1873-1884.
49. White, J. G., Southgate, E. and Thomson, J. N. (1991). On the nature of undead cells in the nematode Caenorhabditis elegans. Philos. Trans. R. Soc. Lond. 331, 263-271.
50. Wodarz, A., Ramrath, A., Grimm, A. and Knust, E. (2000). Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts. J. Cell Biol. 150, 1361-1374.