Human VRK2 modulates apoptosis by interaction with Bcl-xL and regulation of BAX gene expression

Cell Death and Disease

Volumn 4, Issue 2, 2013, Pages

  Monsalve, D M ^a,b   Merced, T ^a   Fernandez I F ^a,b   Blanco, S ^a,c   Vazquez Cedeira M ^a,b   Lazo, P A ^a,b  

^a Inst Biol Molec Y Cel del Cancer   (Spain)

^b HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Apoptosis; Bcl xL; Chemotherapy; Protein protein interactions; VRK2

Indexed keywords

CAMPTOTHECIN; CASPASE; CYTOCHROME C; DOXORUBICIN; LIPOCORTIN 5; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN SERINE THREONINE KINASE; PROTEIN VACCINIA RELATED KINASE 2; PUMA PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CAMPTOTHECIN; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; DOXORUBICIN; GENE EXPRESSION; HEK293 CELLS; HELA CELLS; HUMANS; MITOCHONDRIA; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84875990106     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.40     Document Type: Article

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