Pruritic and vascular responses induced by serotonin in patients with atopic dermatitis and in healthy controls

Acta Dermato-Venereologica

Volumn 93, Issue 3, 2013, Pages 277-280

  Rasul, Aram ^a   Nordlind, Klas ^a   Wahlgren, Carl Fredrik ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Atopic dermatitis; Histamine; Itch; Serotonin; Vascular response

Indexed keywords

BUFFER; HISTAMINE; SEROTONIN;

ADULT; ARTICLE; ATOPIC DERMATITIS; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; INJECTION; LATENT PERIOD; MALE; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT;

ADULT; CASE-CONTROL STUDIES; DERMATITIS, ATOPIC; FEMALE; HISTAMINE; HUMANS; INJECTIONS, INTRADERMAL; MALE; MIDDLE AGED; PRURITUS; REACTION TIME; SENSATION; SEROTONIN; SKIN; TIME FACTORS; YOUNG ADULT;

EID: 84875983472     PISSN: 00015555     EISSN: 16512057     Source Type: Journal    
DOI: 10.2340/00015555-1473     Document Type: Article

References (26)

1. Wahlgren CF. Itch and atopic dermatitis: clinical and experimental studies. Acta Derm Venereol 1991; 165: 1-53.
2. Sonkoly E, Muller A, Lauerma AI, Pivarcsi A, Soto H, Kemeny L, et al. IL-31: a new link between T cells and pruritus in atopic skin infammation. J Allergy Clin Immunol 2006; 117: 411-417.
3. Ständer S, Luger TA. Itch in atopic dermatitis - pathophy-siology and treatment. Acta Dermatovenerol Croat 2010; 18: 289-296.
4. Nordlind K, Azmitia EC, Slominski A. The skin as a mirror of the soul: exploring the possible roles of serotonin. Exp Dermatol 2008; 17: 301-311.
5. Soga F, Katoh N, Inoue T, Kishimoto S. Serotonin activates human monocytes and prevents apoptosis. J Invest Dermatol 2007; 127: 1947-1955.
6. Fjellner B, Hägermark Ö. Pruritus in polycythemia vera: treatment with aspirin and possibility of platelet involvement. Acta Derm Venereol 1979; 59: 505-512.
7. Hägermark Ö. Peripheral and central mediators of itch. Skin Pharmacol Physiol 1992; 5: 1-8.
8. Weisshaar E, Ziethen B, gollnick H. Can a serotonin type 3 (5-HT3) receptor antagonist reduce experimentally-induced itch? Infamm Res 1997; 46: 412-416.
9. Thomsen JS, Sonne M, Benfeldt E, Jensen SB, Serup J, Menné T. Experimental itch in sodium lauryl sulphate-inflamed and normal skin in humans: a randomized, double-blind, placebo-controlled study of histamine and other inducers of itch. Br J Dermatol 2002; 146: 792-800.
10. Schmelz M, Schmidt R, Weidner C, Hilliges M, Torebjörk HE, Handwerker HO. Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens. J Neurophysiol 2003; 89: 2441-2448.
11. Hosogi M, Schmelz M, Miyachi Y, Ikoma A. Bradykinin is a potent pruritogen in atopic dermatitis: a switch from pain to itch. Pain 2006; 126: 16-23.
12. Williams HC, Burney PG, Pembroke AC, Hay RJ. The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis. III. Independent hospital validation. Br J Dermatol 1994; 131: 406-416.
13. Schram ME, Spuls PI, Leefang MM, Lindeboom R, Bos JD, Schmitt J. EASI, (objective) SCORAD and POEM for atopic eczema: responsiveness and minimal clinically important difference. Allergy 2012; 67: 99-106.
14. Fjellner B, Hägermark O. Studies on pruritogenic and histamine-releasing effects of some putative peptide neu-rotransmitters. Acta Derm Venereol 1981; 61: 245-250.
15. Wahlgren CF, Ekblom A, Hägermark Ö. Some aspects of the experimental induction and measurement of itch. Acta Derm Venereol 1989; 69: 185-189.
16. Simone DA, Alreja M, LaMotte RH. Psychophysical studies of the itch sensation and itchy skin ("alloknesis") produced by intracutaneous injection of histamine. Somatosens Mot Res 1991; 8: 271-279.
17. Wahlgren CF, Ekblom A. Perception of histamine-induced itch elicited in three different skin regions. Acta Derm Venereol 1991; 71: 205-208.
18. Wahlgren CF, Tengvall Linder M, Hägermark Ö, Scheynius A. Itch and infammation induced by intradermally injected interleukin-2 in atopic dermatitis patients and healthy subjects. Arch Dermatol Res 1995; 287: 572-580.
19. Amatya B, Nordlind K, Wahlgren CF. Responses to intra-dermal injections of substance P in psoriasis patients with pruritus. Skin Pharmacol Physiol 2010; 23: 133-138.
20. Bernstein L. Proceedings of the task force on guidelines for standardizing old and new technologies used for the diagnosis and treatment of allergic diseases. J Allergy Clin Immunol 1988; 82: 487-526.
21. Hanifn JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol 1980; Suppl 92: 44-47.
22. Lundeberg L, Liang Y, Sundström E, Nordlind K, Ver-hofstad A, Lidén S, et al. Serotonin in human allergic contact dermatitis. An immunohistochemical and high-performance liquid chromatographic study. Arch Dermatol Res 1999; 291: 269-274.
23. Qin HY, Luo JL, Qi SD, Xu HX, Sung JJ, Bian ZX. Visceral hypersensitivity induced by activation of transient receptor potential vanilloid type 1 is mediated through the serotonin pathway in rat colon. Eur J Pharmacol 2010; 647: 75-83.
24. Yamaguchi T, Nagasawa T, Satoh M, Kuraishi Y. Itch-associated response induced by intradermal injection through 5-HT2 receptors in mice. Neurosci Res 1999; 35: 77-83.
25. Jasemian Y, Gazerani P, Dagnaes-Hansen F. Validation of infrared thermography in serotonin-induced itch model in rat. Acta Derm Venereol 2011; 91: 637.
26. Akiyama T, Ivanov M, Nagamine M, Carstens M, Ikoma A, Cevikbas F, et al. Warming enhances serotonin-evoked itch via TRPV4. Acta Derm Venereol 2011; 91: 624-625.