Pepsin is nitrated in the rat stomach, acquiring antiulcerogenic activity: A novel interaction between dietary nitrate and gut proteins

Free Radical Biology and Medicine

Volumn 58, Issue , 2013, Pages 26-34

  Rocha, Bárbara S ^a   Gago, Bruno ^a   Barbosa, Rui M ^a   Lundberg, Jon O ^b   Mann, Giovanni E ^c   Radi, Rafael ^d   Laranjinha, João ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b KAROLINSKA INSTITUTE   (Sweden)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

Author keywords

Dietary nitrite; Free radicals; Gastric ulcer; Pepsin nitration

Indexed keywords

DICLOFENAC; ENZYME PRECURSOR; NITRATE; PENTAGASTRIN; PEPSIN A; PEPSINOGEN; SODIUM NITRITE; WATER;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIULCER ACTIVITY; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; DISEASE COURSE; EXTRACELLULAR MATRIX; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; IN VIVO STUDY; MALE; NITRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; RAT; STOMACH; STOMACH MUCOSA; STOMACH ULCER;

ANIMALS; DIET; GASTRIC MUCOSA; GASTROINTESTINAL TRACT; NITRATES; NITRIC OXIDE; PEPSIN A; PROTEINS; RATS; STOMACH; STOMACH ULCER;

ANIMALIA; RATTUS;

EID: 84875974388     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.12.017     Document Type: Article

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