Antinociceptive activities of lidocaine and the nav1.8 blocker a803467 in diabetic rats

Journal of the American Association for Laboratory Animal Science

Volumn 51, Issue 5, 2012, Pages 579-585

  Mert, Tufan ^a   Gunes, Yasemin ^b  

^a KAHRAMANMARAS SUTCU IMAM UNIVERSITY   (Turkey)

^b CUKUROVA UNIVERSITY   (Turkey)

Author keywords

Streptozotocin; STZ

Indexed keywords

A 803467; ANTINOCICEPTIVE AGENT; LIDOCAINE; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL BLOCKING AGENT;

ALLODYNIA; ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG POTENCY; DRUG RESPONSE; FEMALE; HYPERALGESIA; NEUROPATHIC PAIN; NONHUMAN; PAIN THRESHOLD; RAT; STREPTOZOCIN DIABETES;

ANALGESICS; ANILINE COMPOUNDS; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; FEMALE; FURANS; HUMANS; HYPERALGESIA; LIDOCAINE; NAV1.8 VOLTAGE-GATED SODIUM CHANNEL; RATS; RATS, WISTAR; SODIUM CHANNEL BLOCKERS;

RATTUS;

EID: 84875970622     PISSN: 15596109     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Akopian AN, Souslova V, England S, Okuse K, Ogata N, Ure J, Smith A, Kerr BJ, McMahon SB, Boyce S, Hill R, Stanfa LC, Dickenson AH, Wood JN. 1999. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat Neurosci 2:541-548. (Pubitemid 30491235)
2. Amaya F, Decosterd I, Samad TA, Plumpton C, Tate S, Mannion RJ, Costigan M, Woolf CJ. 2000. Diversity of expression of the sensory-neuron-specific TTX-resistant voltage-gated sodium-ion channels SNS and SNS2. Mol Cell Neurosci 15:331-342. (Pubitemid 30266270)
3. Andriambeloson E, Baillet C, Vitte PA, Garotta G, Dreano M, Callizot N. 2006. Interleukin-6 attenuates the development of experimental diabetes-related neuropathy. Neuropathology 26:32-42.
4. Bean BP. 2007. The action potential in mammalian central neurons. Nat Rev Neurosci 8:451-465. (Pubitemid 46789230)
5. Berkley KJ. 1997. Sex differences in pain. Behav Brain Sci 20:371-380. (Pubitemid 28125800)
6. Calcutt NA. 2002. Potential mechanisms of neuropathic pain in diabetes. Int Rev Neurobiol 50:205-228.
7. Chahine M, Ziane R, Vijayaragavan K, Okamura Y. 2005. Regulation of Nav channels in sensory neurons. Trends Pharmacol Sci 26:496-502. (Pubitemid 41338559)
8. Chong MS, Hester J. 2007. Diabetic painful neuropathy: Current and future treatment options. Drugs 67:569-585. (Pubitemid 46440313)
9. Coggeshall RE, Tate S, Carlton SM. 2004. Differential expression of tetrodotoxin-resistant sodium channels Nav1.8 and Nav1.9 in normal and inflamed rats. Neurosci Lett 355:45-48. (Pubitemid 38077181)
10. Courteix C, Eschalier A, Lavarenne J. 1993. Streptozocin-induced diabetic rats: Behavioural evidence for a model of chronic pain. Pain 53:81-88. (Pubitemid 23137271)
11. Cummins TR, Waxman SG. 1997. Downregulation of tetrodotoxinresistant sodium currents and upregulation of a rapidly repriming tetrodotoxin sensitive sodium current in small spinal sensory neurons after nerve injury. J Neurosci 17:3503-3514. (Pubitemid 27200579)
12. Devor M. 2006. Sodium channels and mechanisms of neuropathic pain. J Pain 7:S3-S12. (Pubitemid 43106683)
13. Dib-Hajj SD, Cummins TR, Black JA, Waxman SG. 2010. Sodium channels in normal and pathological pain. Annu Rev Neurosci 33:325-347.
14. Erichsen HK, Hao JX, Xu XJ, Munro GB. 2003. A comparison of the antinociceptive effects of voltage-activated Na channel blockers in 2 rat models of neuropathic pain. Eur J Pharmacol 458:275-282. (Pubitemid 36009466)
15. Fox A, Eastwood C, Gentry C, Manning D, Urban L. 1999. Critical evaluation of the streptozotocin model of painful diabetic neuropathy in the rat. Pain 81:307-316. (Pubitemid 29257901)
16. Fuchs D, Birklein F, Reeh PW, Sauer SK. 2010. Sensitized peripheral nociception in experimental diabetes of the rat. Pain 151:496-505.
17. Gilron I, Watson CPN, Cahill CM, Moulin DE. 2006. Neuropathic pain: A practical guide for the clinician. Can Med Assoc J 175:265-275. (Pubitemid 44230827)
18. Greenspan JD, Craft RM, LeResche L, Arendt-Nielsen L, Berkley KJ, Fillingim RB, Gold MS, Holdcroft A, Lautenbacher S, Mayer EA, Mogil JS, Murphy AZ, Traub RJ; Consensus Working Group of the Sex, Gender, and Pain SIG of the IASP. 2007. Studying sex and gender differences in pain and analgesia: A consensus report. Pain 132:S26-S45. (Pubitemid 350026210)
19. Hargreaves K, Dubner R, Broun F, Flores C, Joris J. 1988. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77-88.
20. Hirade M, Yasuda H, Omatsu-Kanbe M, Kikkawa R, Kitasato H. 1999. Tetrodotoxin-resistant sodium channels of dorsal root ganglion neurons are readily activated in diabetic rats. Neuroscience 90:933-939. (Pubitemid 29156758)
21. Hong S, Morrow TJ, Paulson PE, Isom LL, Wiley JW. 2004. Early painful diabetic neuropathy is associated with differential changes in tetrodotoxin-sensitive and-resistant sodium channels in dorsal root ganglion neurons in the rat. J Biol Chem 279:29341-29350. (Pubitemid 38915812)
22. Huizinga MM, Peltier A. 2007. Painful diabetic neuropathy: A management-centered review. Clin Diab 25:6-15.
23. Jarvis MF, Honore P, Shieh CC, Chapman M, Joshi S, Zhang XF, Kort M, Carroll W, Marron B, Atkinson R, Thomas J, Liu D, Krambis M, Liu Y, McGaraughty S, Chu K, Roeloffs R, Zhong C, Mikusa JP, Hernandez G, Gauvin D, Wade C, Zhu C, Pai M, Scanio M, Shi L, Drizin I, Gregg R, Matulenko M, Hakeem A, Gross M, Johnson M, Marsh K, Wagoner PK, Sullivan JP, Faltynek CR, Krafte DS. 2007. A803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci USA 104:8520-8525. (Pubitemid 47175520)
24. Joshi SK, Honore P, Hernandez G, Schmidt R, Gomtsyan A, Scanio M, Kort M, Jarvis MF. 2009. Additive antinociceptive effects of the selective Nav1.8 blocker A803467 and selective TRPV1 antagonists in rat inflammatory and neuropathic pain models. J Pain 10:306-315.
25. Joshi SK, Mikusa JP, Hernandez G, Baker S, Shieh CC, Neelands T, Zhang XF, Niforatos W, Kage K, Han P, Krafte D, Faltynek C, Sullivan JP, Jarvis MF, Honore P. 2006. Involvement of the TTXresistant sodium channel Nav1.8 in inflammatory and neuropathic, but not postoperative, pain states. Pain 123:75-82. (Pubitemid 43816759)
26. Kapur D. 2003. Neuropathic pain and diabetes. Diabetes Metab Res Rev 19:S9-S15. (Pubitemid 36285367)
27. Khan GM, Chen SR, Pan HL. 2002. Role of primary afferent nerves in allodynia caused by diabetic neuropathy in rats. Neuroscience 114:291-299. (Pubitemid 35245410)
28. Kitano Y, Kuwabara S, Misawa S, Ogawara K, Kanai K, Kikkawa Y, Yagui K, Hattori T. 2004. The acute effects of glycemic control on axonal excitability in human diabetics. Ann Neurol 56:462-467. (Pubitemid 39319335)
29. Krishnan AV, Lin CS, Kiernan MC. 2008. Activity-dependent excitability changes suggest Na+/K+ pump dysfunction in diabetic neuropathy. Brain 131:1209-1216.
30. Lai J, Gold MS, Kim CS, Bian D, Ossipov MH, Hunter JC, Porreca F. 2002. Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel Nav1.8. Pain 95:143-152. (Pubitemid 34076786)
31. Liu M, Wood JN. 2011. The roles of sodium channels in nociception: Implications for mechanisms of neuropathic pain. Pain Med 12:S93-S99.
32. Mao J, Chen LL. 2000. Systemic lidocaine for neuropathic pain relief. Pain 87:7-17. (Pubitemid 30345657)
33. McGaraughty S, Chu KL, Scanio MJC, Kort ME, Faltynek CE, Jarvis MF. 2008. A selective Nav1.8 sodium channel blocker, A803467 [5-(4-Chlorophenyl-N-(3,5- dimethoxyphenyl)furan-2-carboxamide], attenuates spinal neuronal activity in neuropathic rats. J Pharmacol Exp Ther 324:1204-1211. (Pubitemid 351397859)
34. Mert T, Gunay I, Ocal I, Inal TC, Sencar L, Polat S. 2009. Macrophage depletion delays progression of neuropathic pain in diabetic animals. Naunyn Schmiedebergs Arch Pharmacol 379:445-452.
35. Mert T, Gunes Y, Gunay I. 2007. Local analgesic efficacy of tramadol following intraplantar injection. Eur J Pharmacol 558:68-72. (Pubitemid 46328871)
36. Misawa S, Sakurai K, Shibuya K, Isose S, Kanai K, Ogino J, Ishikawa K, Kuwabara S. 2009. Neuropathic pain is associated with increased nodal persistent Na+ currents in human diabetic neuropathy. J Peripher Nerv Syst 14:279-284.
37. Ng A, Smith G. 2002. I: Intraperitoneal administration of analgesia: Is this practice of any utility? Br J Anaesth 89:535-537. (Pubitemid 35153771)
38. Novakovic SD, Tzoumaka E, McGivern JG, Haraguchi M, Sangameswa-ran L, Gogas KR, Eglen RM, Hunter JC. 1998. Distribution of the tetrodotoxin-resistant sodium channel PN3 in rat sensory neurons in normal and neuropathic conditions. J Neurosci 18:2174-2187. (Pubitemid 28141422)
39. Priest BT. 2009. Future potential and status of selective sodium channel blockers for the treatment of pain. Curr Opin Drug Discov Devel 12:682-692.
40. Rogers M, Tang L, Madge DJ, Stevens EB. 2006. The role of sodium channels in neuropathic pain. Semin Cell Dev Biol 17:571-581. (Pubitemid 46110815)
41. Sheets PL, Heers C, Stoehr T, Cummins TR. 2008. Differential block of sensory neuronal voltage-gated sodium channels by lacosamide, lidocaine, and carbamazepine. J Pharmacol Exp Ther 326:89-99. (Pubitemid 351872141)
42. Sima AA, Sugimoto K. 1999. Experimental diabetic neuropathy: An update. Diabetologia 42:773-788. (Pubitemid 29325066)
43. Suzuki Y, Sato J, Kawanishi M, Mizumra K. 2002. Lowered response threshold and increased responsiveness to mechanical stimulation of cutaneous nociceptive fibers in streptozotocin diabetic rat skin-in vitro correlates of mechanical allodynia and hyperalgesia observed in the early stage of diabetes. Neurosci Res 43:171-178. (Pubitemid 34627048)
44. Wood JN, Boorman JP, Okuse K, Baker MD. 2004. Voltage-gated sodium channels and pain pathways. J Neurobiol 61:55-71. (Pubitemid 39287770)
45. Zimmermann M. 1983. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16:109-110. (Pubitemid 13058546)
46. Zuliani V, Rivara M, Fantini M, Costantino G. 2010. Sodium channel blockers for neuropathic pain. Expert Opin Ther Pat 20:755-779.