Development and characterization of an SMN2-based intermediate mouse model of spinal muscular atrophy

Human Molecular Genetics

Volumn 22, Issue 9, 2013, Pages 1843-1855

  Cobb, Melissa S ^a   Rose, Ferril F ^b   Rindt, Hansjörg ^a   Glascock, Jacqueline J ^a,b   Shababi, Monir ^a   Miller, Madeline R ^a   Osman, Erkan Y ^a,b   Yen, Pei Fen ^a   Garcia, Michael L ^a   Martin, Brittanie R ^a   Wetz, Mary J ^a   Mazzasette, Chiara ^c   Feng, Zhihua ^c   Ko, Chien Ping ^c   Lorson, Christian L ^a,b  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; SURVIVAL MOTOR NEURON PROTEIN 1; SURVIVAL MOTOR NEURON PROTEIN 2;

5' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CELL SURVIVAL; DISEASE SEVERITY; EXON; FIBROSING ALVEOLITIS; GASTROCNEMIUS MUSCLE; GENE MUTATION; GENOTYPE; GRIP STRENGTH; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; INHERITANCE; LUMBAR SPINAL CORD; MOTONEURON; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOUSE; MUSCLE CELL; NERVE CELL DEGENERATION; NEUROMUSCULAR SYNAPSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN STABILITY; SINGLE NUCLEOTIDE POLYMORPHISM; SPINAL MUSCULAR ATROPHY; STOP CODON; TRANSGENE;

ANIMALS; BODY WEIGHT; BRAIN; DISEASE MODELS, ANIMAL; EXONS; GENE EXPRESSION REGULATION; HUMANS; LONGEVITY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCULAR ATROPHY, SPINAL; PHENOTYPE; PROMOTER REGIONS, GENETIC; RNA; RNA SPLICING; SPINAL CORD; SURVIVAL OF MOTOR NEURON 1 PROTEIN; SURVIVAL OF MOTOR NEURON 2 PROTEIN;

ANIMALIA;

EID: 84875928098     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt037     Document Type: Article

References (54)

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