Development of a recombinant antibody to target peptides and proteins to sialoadhesin-expressing macrophages

BMC Biotechnology

Volumn 13, Issue , 2013, Pages

  Ooms, Karen ^a   Van Gorp, Hanne ^a   Van Gaever, Tim ^a   Nauwynck, Hans J ^a   Delputte, Peter L ^b  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

CD169; Cell directed therapy; Macrophage; Recombinant antibody; Sialoadhesin; Siglec 1; Targeting

Indexed keywords

CD169; CELL-DIRECTED THERAPY; RECOMBINANT ANTIBODY; SIALOADHESIN; SIGLEC-1; TARGETING;

CHROMATOGRAPHY; CLONING; CYTOLOGY; ENZYME ACTIVITY; MACROPHAGES; MOLECULAR BIOLOGY; MOLECULES; MONOCLONAL ANTIBODIES; OPTIMIZATION; PEPTIDES; PURIFICATION; RECOMBINANT PROTEINS;

TIN;

IMMUNOGLOBULIN G; RECOMBINANT ANTIBODY; RECOMBINANT ANTIBODY REC41D3; SIALOADHESIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CONTROLLED STUDY; CULTURE MEDIUM; ENDOCYTOSIS; ENDOSOME; HEAVY CHAIN; MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SECRETION; PROTEIN TARGETING; SEQUENCE ANALYSIS; STOP CODON;

ANIMALS; ANTIBODIES, MONOCLONAL; ENDOCYTOSIS; ENDOSOMES; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN VARIABLE REGION; LYSOSOMES; MACROPHAGES; MICE; RECOMBINANT FUSION PROTEINS; SIALIC ACID BINDING IG-LIKE LECTIN 1; SWINE; TRANSFECTION;

ANIMALIA; SUS;

EID: 84875925576     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-13-33     Document Type: Article

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