Transcriptional cofactor TBLR1 controls lipid mobilization in white adipose tissue

Cell Metabolism

Volumn 17, Issue 4, 2013, Pages 575-585

  Rohm, Maria ^a   Sommerfeld, Anke ^a   Strzoda, Daniela ^a   Jones, Allan ^a   Sijmonsma, Tjeerd P ^a   Rudofsky, Gottfried ^b   Wolfrum, Christian ^c   Sticht, Carsten ^d   Gretz, Norbert ^d   Zeyda, Maximilian ^e   Leitner, Lukas ^e   Nawroth, Peter P ^b   Stulnig, Thomas M ^e   Diaz, Mauricio Berriel ^a   Vegiopoulos, Alexandros ^a   Herzig, Stephan ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c SWISS FEDERAL INSTITUTE OF TECHNOLOGY   (Switzerland)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; FATTY ACID; PROTEIN TRANSDUCIN BETA LIKE RELATED 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FATTY ACID BLOOD LEVEL; FEMALE; GENE INACTIVATION; GLUCOSE INTOLERANCE; HUMAN; INSULIN RESISTANCE; LIPID DIET; LIPID METABOLISM; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WHITE ADIPOSE TISSUE;

3T3-L1 CELLS; ADIPOSE TISSUE, WHITE; ANIMALS; CYCLIC AMP; DIET, HIGH-FAT; FATTY ACIDS, NONESTERIFIED; HUMANS; INSULIN RESISTANCE; LIPID MOBILIZATION; LIPOLYSIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; OBESITY; RECEPTORS, ADRENERGIC; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

MUS;

EID: 84875908666     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2013.02.010     Document Type: Article

References (48)

1. S.I. Anghel, E. Bedu, C.D. Vivier, P. Descombes, B. Desvergne, and W. Wahli Adipose tissue integrity as a prerequisite for systemic energy balance: a critical role for peroxisome proliferator-activated receptor gamma J. Biol. Chem. 282 2007 29946 29957
2. P. Arner, S. Bernard, M. Salehpour, G. Possnert, J. Liebl, P. Steier, B.A. Buchholz, M. Eriksson, E. Arner, and H. Hauner Dynamics of human adipose lipid turnover in health and metabolic disease Nature 478 2011 110 113
3. I. Dahlman, and P. Arner Genetics of adipose tissue biology Prog Mol Biol Transl Sci 94 2010 39 74
4. M.M. Finucane, G.A. Stevens, M.J. Cowan, G. Danaei, J.K. Lin, C.J. Paciorek, G.M. Singh, H.R. Gutierrez, Y. Lu, A.N. Bahalim Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index) National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants Lancet 377 2011 557 567
5. K.N. Frayn, C.M. Williams, and P. Arner Are increased plasma non-esterified fatty acid concentrations a risk marker for coronary heart disease and other chronic diseases? Clin. Sci. 90 1996 243 253
6. J.E. Galgani, C. Moro, and E. Ravussin Metabolic flexibility and insulin resistance Am. J. Physiol. Endocrinol. Metab. 295 2008 E1009 E1017
7. S. Galic, J.S. Oakhill, and G.R. Steinberg Adipose tissue as an endocrine organ Mol. Cell. Endocrinol. 316 2010 129 139
8. M.G. Guenther, W.S. Lane, W. Fischle, E. Verdin, M.A. Lazar, and R. Shiekhattar A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness Genes Dev. 14 2000 1048 1057
9. B. Haas, P. Mayer, K. Jennissen, D. Scholz, M. Berriel Diaz, W. Bloch, S. Herzig, R. Fässler, and A. Pfeifer Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis Sci. Signal. 2 2009 ra78
10. G. Haemmerle, R. Zimmermann, M. Hayn, C. Theussl, G. Waeg, E. Wagner, W. Sattler, T.M. Magin, E.F. Wagner, and R. Zechner Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis J. Biol. Chem. 277 2002 4806 4815
11. G. Haemmerle, A. Lass, R. Zimmermann, G. Gorkiewicz, C. Meyer, J. Rozman, G. Heldmaier, R. Maier, C. Theussl, and S. Eder Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase Science 312 2006 734 737
12. G. Haemmerle, T. Moustafa, G. Woelkart, S. Büttner, A. Schmidt, T. van de Weijer, M. Hesselink, D. Jaeger, P.C. Kienesberger, and K. Zierler ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1 Nat. Med. 17 2011 1076 1085
13. W. He, Y. Barak, A. Hevener, P. Olson, D. Liao, J. Le, M. Nelson, E. Ong, J.M. Olefsky, and R.M. Evans Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle Proc. Natl. Acad. Sci. USA 100 2003 15712 15717
14. S. Herzig, F. Long, U.S. Jhala, S. Hedrick, R. Quinn, A. Bauer, D. Rudolph, G. Schutz, C. Yoon, and P. Puigserver CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 Nature 413 2001 179 183
15. S. Herzig, S. Hedrick, I. Morantte, S.H. Koo, F. Galimi, and M. Montminy CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma Nature 426 2003 190 193
16. G.S. Hotamisligil Inflammation and metabolic disorders Nature 444 2006 860 867
17. J.W. Jocken, D. Langin, E. Smit, W.H. Saris, C. Valle, G.B. Hul, C. Holm, P. Arner, and E.E. Blaak Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state J. Clin. Endocrinol. Metab. 92 2007 2292 2299
18. F. Karpe, J.R. Dickmann, and K.N. Frayn Fatty acids, obesity, and insulin resistance: time for a reevaluation Diabetes 60 2011 2441 2449
19. P. Kulozik, A. Jones, F. Mattijssen, A.J. Rose, A. Reimann, D. Strzoda, S. Kleinsorg, C. Raupp, J. Kleinschmidt, and K. Müller-Decker Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia Cell Metab. 13 2011 389 400
20. D. Langin In and out: adipose tissue lipid turnover in obesity and dyslipidemia Cell Metab. 14 2011 569 570
21. D. Langin, A. Dicker, G. Tavernier, J. Hoffstedt, A. Mairal, M. Rydén, E. Arner, A. Sicard, C.M. Jenkins, and N. Viguerie Adipocyte lipases and defect of lipolysis in human obesity Diabetes 54 2005 3190 3197
22. V. Large, S. Reynisdottir, D. Langin, K. Fredby, M. Klannemark, C. Holm, and P. Arner Decreased expression and function of adipocyte hormone-sensitive lipase in subcutaneous fat cells of obese subjects J. Lipid Res. 40 1999 2059 2066
23. A. Lass, R. Zimmermann, G. Haemmerle, M. Riederer, G. Schoiswohl, M. Schweiger, P. Kienesberger, J.G. Strauss, G. Gorkiewicz, and R. Zechner Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome Cell Metab. 3 2006 309 319
24. P. Li, W. Fan, J. Xu, M. Lu, H. Yamamoto, J. Auwerx, D.D. Sears, S. Talukdar, D. Oh, and A. Chen Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity Cell 147 2011 815 826
25. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 2001 402 408
26. S.E. McQuaid, L. Hodson, M.J. Neville, A.L. Dennis, J. Cheeseman, S.M. Humphreys, T. Ruge, M. Gilbert, B.A. Fielding, K.N. Frayn, and F. Karpe Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition? Diabetes 60 2011 47 55
27. A. Ostertag, A. Jones, A.J. Rose, M. Liebert, S. Kleinsorg, A. Reimann, A. Vegiopoulos, M. Berriel Diaz, D. Strzoda, and M. Yamamoto Control of adipose tissue inflammation through TRB1 Diabetes 59 2010 1991 2000
28. J. Osuga, S. Ishibashi, T. Oka, H. Yagyu, R. Tozawa, A. Fujimoto, F. Shionoiri, N. Yahagi, F.B. Kraemer, O. Tsutsumi, and N. Yamada Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity Proc. Natl. Acad. Sci. USA 97 2000 787 792
29. V. Perissi, K. Jepsen, C.K. Glass, and M.G. Rosenfeld Deconstructing repression: evolving models of co-repressor action Nat. Rev. Genet. 11 2010 109 123
30. L. Qi, M. Saberi, E. Zmuda, Y. Wang, J. Altarejos, X. Zhang, R. Dentin, S. Hedrick, G. Bandyopadhyay, and T. Hai Adipocyte CREB promotes insulin resistance in obesity Cell Metab. 9 2009 277 286
31. N. Rasouli, and P.A. Kern Adipocytokines and the metabolic complications of obesity J. Clin. Endocrinol. Metab. 93 11, Suppl 1 2008 S64 S73
32. M.S. Rodeheffer, K. Birsoy, and J.M. Friedman Identification of white adipocyte progenitor cells in vivo Cell 135 2008 240 249
33. S. Rodriguez-Cuenca, S. Carobbio, V.R. Velagapudi, N. Barbarroja, J.M. Moreno-Navarrete, F.J. Tinahones, J.M. Fernandez-Real, M. Orešic, and A. Vidal-Puig Peroxisome proliferator-activated receptor γ-dependent regulation of lipolytic nodes and metabolic flexibility Mol. Cell. Biol. 32 2012 1555 1565
34. S. Rodriguez-Cuenca, S. Carobbio, and A. Vidal-Puig Ablation of Pparg2 impairs lipolysis and reveals murine strain differences in lipolytic responses FASEB J. 26 2012 1835 1844
35. A.J. Rose, M.B. Díaz, A. Reimann, J. Klement, T. Walcher, A. Krones-Herzig, O. Strobel, J. Werner, A. Peters, and A. Kleyman Molecular control of systemic bile acid homeostasis by the liver glucocorticoid receptor Cell Metab. 14 2011 123 130
36. G. Rudofsky, E. Roeder, T. Merle, M. Hildebrand, P.P. Nawroth, and C. Wolfrum Weight loss improves endothelial function independently of ADMA reduction in severe obesity Horm. Metab. Res. 43 2011 343 348
37. D. Samocha-Bonet, D.J. Chisholm, K. Tonks, L.V. Campbell, and J.R. Greenfield Insulin-sensitive obesity in humans - a 'favorable fat' phenotype? Trends Endocrinol. Metab. 23 2012 116 124
38. V.T. Samuel, and G.I. Shulman Mechanisms for insulin resistance: common threads and missing links Cell 148 2012 852 871
39. R. Sandberg, and O. Larsson Improved precision and accuracy for microarrays using updated probe set definitions BMC Bioinformatics 8 2007 48
40. W.J. Shen, Z. Yu, S. Patel, D. Jue, L.F. Liu, and F.B. Kraemer Hormone-sensitive lipase modulates adipose metabolism through PPARγ Biochim. Biophys. Acta 1811 2011 9 16
41. A. Sommerfeld, A. Krones-Herzig, and S. Herzig Transcriptional co-factors and hepatic energy metabolism Mol. Cell. Endocrinol. 332 2011 21 31
42. U. Taschler, F.P. Radner, C. Heier, R. Schreiber, M. Schweiger, G. Schoiswohl, K. Preiss-Landl, D. Jaeger, B. Reiter, and H.C. Koefeler Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance J. Biol. Chem. 286 2011 17467 17477
43. M.H. Tschöp, J.R. Speakman, J.R. Arch, J. Auwerx, J.C. Brüning, L. Chan, R.H. Eckel, R.V. Farese Jr., J.E. Galgani, and C. Hambly A guide to analysis of mouse energy metabolism Nat. Methods 9 2012 57 63
44. J. Villa, and R.E. Pratley Adipose tissue dysfunction in polycystic ovary syndrome Curr. Diab. Rep. 11 2011 179 184
45. J.W. Wu, S.P. Wang, S. Casavant, A. Moreau, G.S. Yang, and G.A. Mitchell Fasting energy homeostasis in mice with adipose deficiency of desnutrin/adipose triglyceride lipase Endocrinology 153 2012 2198 2207
46. Y.H. Yu, and H.N. Ginsberg Adipocyte signaling and lipid homeostasis: sequelae of insulin-resistant adipose tissue Circ. Res. 96 2005 1042 1052
47. R. Zechner, P.C. Kienesberger, G. Haemmerle, R. Zimmermann, and A. Lass Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores J. Lipid Res. 50 2009 3 21
48. R. Zechner, R. Zimmermann, T.O. Eichmann, S.D. Kohlwein, G. Haemmerle, A. Lass, and F. Madeo FAT SIGNALS - lipases and lipolysis in lipid metabolism and signaling Cell Metab. 15 2012 279 291