TypA is involved in virulence, antimicrobial resistance and biofilm formation in Pseudomonas aeruginosa

BMC Microbiology

Volumn 13, Issue 1, 2013, Pages

  Neidig, Anke ^a   Yeung, Amy Ty ^b   Rosay, Thibaut ^c   Tettmann, Beatrix ^a   Strempel, Nikola ^a   Rueger, Martina ^a   Lesouhaitier, Olivier ^c   Overhage, Joerg ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITÉ DE ROUEN   (France)

Author keywords

Biofilm; Dictyostelium discoideum; Macrophage; Pathogen; Pseudomonas aeruginosa; Resistance; TypA; Type III secretion system; Virulence

Indexed keywords

BETA LACTAM; GUANOSINE TRIPHOSPHATASE; POLYPEPTIDE ANTIBIOTIC AGENT; TETRACYCLINE; TYPA PROTEIN; UNCLASSIFIED DRUG;

AMOEBA (LIFE CYCLE STAGE); ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL VIRULENCE; BIOFILM; CELL ADHESION; CONTROLLED STUDY; DOWN REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; MACROPHAGE; NONHUMAN; PHENOTYPE; PSEUDOMONAS AERUGINOSA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMOEBA; BACTERIAL ADHESION; BIOFILMS; CELLS, CULTURED; DRUG RESISTANCE, BACTERIAL; ENDOCYTOSIS; GENE EXPRESSION PROFILING; GTP PHOSPHOHYDROLASES; HUMANS; MACROPHAGES; MUTATION; PSEUDOMONAS AERUGINOSA; REAL-TIME POLYMERASE CHAIN REACTION; VIRULENCE FACTORS;

DICTYOSTELIUM DISCOIDEUM; NEGIBACTERIA; PSEUDOMONAS AERUGINOSA;

EID: 84875894038     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-13-77     Document Type: Article

References (52)

1. Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Nature 2000 406 6799 959 964
2. Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Govan JR, Deretic V, Microbiol Rev 1996 60 3 539 574
3. Pseudomonas aeruginosa: all roads lead to resistance. Breidenstein EB, de la Fuente-Nunez C, Hancock RE, Trends Microbiol 2011 19 8 419 426
4. Genome-wide identification of pseudomonas aeruginosa virulence-related genes using a caenorhabditis elegans infection model. Feinbaum RL, Urbach JM, Liberati NT, Djonovic S, Adonizio A, Carvunis AR, Ausubel FM, PLoS Pathog 2012 8 7 1002813
5. The type III secretion system of Pseudomonas aeruginosa: infection by injection. Hauser AR, Nat Rev Microbiol 2009 7 9 654 665
6. Protein secretion systems in pseudomonas aeruginosa: an essay on diversity, evolution, and function. Filloux A, Front Microbiol 2011 2 155
7. Central role of quorum sensing in regulating the production of pathogenicity factors in Pseudomonas aeruginosa. Girard G, Bloemberg GV, Future Microbiol 2008 3 1 97 106
8. P. aeruginosa quorum-sensing systems and virulence. Smith RS, Iglewski BH, Curr Opin Microbiol 2003 6 1 56 60
9. Caenorhabditis elegans as a host for the study of host-pathogen interactions. Aballay A, Ausubel FM, Curr Opin Microbiol 2002 5 1 97 101
10. What can Dictyostelium bring to the study of Pseudomonas infections? Lima WC, Lelong E, Cosson P, Semin Cell Dev Biol 2011 22 1 77 81
11. Virulence on the fly: drosophila melanogaster as a model genetic organism to decipher host-pathogen interactions. Limmer S, Quintin J, Hetru C, Ferrandon D, Curr Drug Targets 2011 12 7 978 999
12. SsTypA1, a chloroplast-specific TypA/BipA-type GTPase from the halophytic plant Suaeda salsa, plays a role in oxidative stress tolerance. Wang F, Zhong NQ, Gao P, Wang GL, Wang HY, Xia GX, Plant Cell Environ 2008 31 7 982 994
13. TypA is a virulence regulator and is present in many pathogenic bacteria. Scott K, Diggle MA, Clarke SC, Br J Biomed Sci 2003 60 3 168 170
14. The universally conserved prokaryotic GTPases. Verstraeten N, Fauvart M, Versees W, Michiels J, Microbiol Mol Biol Rev 2011 75 3 507 542 second and third pages of table of contents
15. Salmonella enterica serovar Typhimurium BipA exhibits two distinct ribosome binding modes. DeLivron MA, Robinson VL, J Bacteriol 2008 190 17 5944 5952
16. Role of GTPases in bacterial ribosome assembly. Britton RA, Annu Rev Microbiol 2009 63 155 176
17. Structure-based design and screening of inhibitors for an essential bacterial GTPase, Der. Hwang J, Tseitin V, Ramnarayan K, Shenderovich MD, Inouye M, J Antibiot (Tokyo) 2012 65 5 237 243
18. Co-ordination of pathogenicity island expression by the BipA GTPase in enteropathogenic Escherichia coli (EPEC). Grant AJ, Farris M, Alefounder P, Williams PH, Woodward MJ, O'Connor CD, Mol Microbiol 2003 48 2 507 521
19. BipA: a tyrosine-phosphorylated GTPase that mediates interactions between enteropathogenic Escherichia coli (EPEC) and epithelial cells. Farris M, Grant A, Richardson TB, O'Connor CD, Mol Microbiol 1998 28 2 265 279
20. The typA gene is required for stress adaptation as well as for symbiosis of Sinorhizobium meliloti 1021 with certain Medicago truncatula lines. Kiss E, Huguet T, Poinsot V, Batut J, Mol Plant Microbe Interact 2004 17 3 235 244
21. Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis. Beckering CL, Steil L, Weber MH, Volker U, Marahiel MA, J Bacteriol 2002 184 22 6395 6402
22. Identification of genes involved in swarming motility using a Pseudomonas aeruginosa PAO1 mini-Tn5-lux mutant library. Overhage J, Lewenza S, Marr AK, Hancock RE, J Bacteriol 2007 189 5 2164 2169
23. The Lon protease is essential for full virulence in Pseudomonas aeruginosa. Breidenstein EBM L, Janot J, Strehmel L, Fernandez PK, Taylor I, Kukavica-Ibrulj SL, Gellatly RC, Levesque J, Overhage LJ, Hancock REW, PLoS One 2012 7 11 49123
24. Genotyping of environmental and clinical Stenotrophomonas maltophilia isolates and their pathogenic potential. Adamek M, Overhage J, Bathe S, Winter J, Fischer R, Schwartz T, PLoS One 2011 6 11 27615
25. An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants (vol 103, pg 2833, 2006). Liberati NT, Urbach JM, Miyata S, Lee DG, Drenkard E, Wu G, Villanueva J, Wei T, Ausubel FM, P Natl Acad Sci USA 2006 103 52 19931 19931
26. Type III secretion-mediated killing of endothelial cells by Pseudomonas aeruginosa. Saliba AM, Filloux A, Ball G, Silva ASV, Assis MC, Plotkowski MC, Microb Pathogenesis 2002 33 4 153 166
27. Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Tan MW, Rahme LG, Sternberg JA, Tompkins RG, Ausubel FM, P Natl Acad Sci USA 1999 96 5 2408 2413
28. Identifying Escherichia coli genes involved in intrinsic multidrug resistance. Duo M, Hou S, Ren D, Appl Microbiol Biotechnol 2008 81 4 731 741
29. Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae. Matz C, Moreno AM, Alhede M, Manefield M, Hauser AR, Givskov M, Kjelleberg S, ISME J 2008 2 8 843 852
30. Discovery and characterization of inhibitors of Pseudomonas aeruginosa type III secretion. Aiello D, Williams JD, Majgier-Baranowska H, Patel I, Peet NP, Huang J, Lory S, Bowlin TL, Moir DT, Antimicrob Agents Chemother 2010 54 5 1988 1999
31. A novel domain in translational GTPase BipA mediates interaction with the 70S ribosome and influences GTP hydrolysis. DeLivron MA, Makanji HS, Lane MC, Robinson VL, Biochemistry 2009 48 44 10533 10541
32. Modulation of enteropathogenic Escherichia coli virulence by quorum sensing. Sircili MP, Walters M, Trabulsi LR, Sperandio V, Infect Immun 2004 72 4 2329 2337
33. Analysis of expression and regulatory functions of the ribosome-binding protein TypA in Mycobacterium tuberculosis under stress conditions. Micklinghoff JC, Schmidt M, Geffers R, Tegge W, Bange FC, Arch Microbiol 2010 192 6 499 504
34. Transcriptional regulation of the Pseudomonas aeruginosa type III secretion system. Yahr TL, Wolfgang MC, Mol Microbiol 2006 62 3 631 640
35. The Pseudomonas aeruginosa PA14 type III secretion system is expressed but not essential to virulence in the Caenorhabditis elegans-P. aeruginosa pathogenicity model. Wareham DW, Papakonstantinopoulou A, Curtis MA, FEMS Microbiol Lett 2005 242 2 209 216
36. Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa. Darby C, Cosma CL, Thomas JH, Manoil C, P Natl Acad Sci USA 1999 96 26 15202 15207
37. Salmonella typhimurium responses to a bactericidal protein from human neutrophils. Qi SY, Li Y, Szyroki A, Giles IG, Moir A, O'Connor CD, Mol Microbiol 1995 17 3 523 531
38. Formate protects stationary-phase Escherichia coli and Salmonella cells from killing by a cationic antimicrobial peptide. Barker HC, Kinsella N, Jaspe A, Friedrich T, O'Connor CD, Mol Microbiol 2000 35 6 1518 1529
39. The clinical impact of bacterial biofilms. Hoiby N, Ciofu O, Johansen HK, Song ZJ, Moser C, Jensen PO, Molin S, Givskov M, Tolker-Nielsen T, Bjarnsholt T, Int J Oral Sci 2011 3 2 55 65
40. The immune system vs Pseudomonas aeruginosa biofilms. Jensen PO, Givskov M, Bjarnsholt T, Moser C, FEMS Immunol Med Microbiol 2010 59 3 292 305
41. Mechanisms of biofilm resistance to antimicrobial agents. Mah TF, O'Toole GA, Trends Microbiol 2001 9 1 34 39
42. Construction of improved Escherichia-Pseudomonas shuttle vectors derived from pUC18/19 and sequence of the region required for their replication in Pseudomonas aeruginosa. West SE, Schweizer HP, Dall C, Sample AK, Runyen-Janecky LJ, Gene 1994 148 1 81 86
43. A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Hoang TT, Karkhoff-Schweizer RR, Kutchma AJ, Schweizer HP, Gene 1998 212 1 77 86
44. The sensor kinase CbrA is a global regulator that modulates metabolism, virulence, and antibiotic resistance in Pseudomonas aeruginosa. Yeung AT, Bains M, Hancock RE, J Bacteriol 2011 193 4 918 931
45. Protocols for growth and development of Dictyostelium discoideum. Fey P, Kowal AS, Gaudet P, Pilcher KE, Chisholm RL, Nat Protoc 2007 2 6 1307 1316
46. Uncoupling scavenger receptor A-mediated phagocytosis of bacteria from endotoxic shock resistance. Amiel E, Acker JL, Collins RM, Berwin B, Infect Immun 2009 77 10 4567 4573
47. Sulston J, Hodgkin J, The Nematode Caenorhabditis elegans Wood: W. B 1988
48. Maintenance of C. elegans. Stiernagle T, C. elegans. A practical approach Oxford, United Kingdom: Oxford University Press, Hope IA, 1999 51 67
49. C-type natriuretic peptide modulates quorum sensing molecule and toxin production in Pseudomonas aeruginosa. Blier AS, Veron W, Bazire A, Gerault E, Taupin L, Vieillard J, Rehel K, Dufour A, Le Derf F, Orange N, Microbiology 2011 157 Pt 7 1929 1944
50. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Wiegand I, Hilpert K, Hancock RE, Nat Protoc 2008 3 2 163 175
51. Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms. Friedman L, Kolter R, Mol Microbiol 2004 51 3 675 690
52. The Lon protease of Pseudomonas aeruginosa is induced by aminoglycosides and is involved in biofilm formation and motility. Marr AK, Overhage J, Bains M, Hancock RE, Microbiology 2007 153 Pt 2 474 482