High expression of p300 is linked to aggressive features and poor prognosis of Nasopharyngeal Carcinoma

Journal of Translational Medicine

Volumn 10, Issue 1, 2012, Pages

  Liao, Zhi Wei ^a   Zhou, Tong Chong ^a   Tan, Xiao Jun ^a   Song, Xian Lu ^a   Liu, Yuan ^a   Shi, Xing Yuan ^a   Huang, Wen Jin ^a   Du, Li Li ^a   Tu, Bo Jun ^a   Lin, Xiao dan ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Immunohistochemistry; Nasopharyngeal carcinoma; p300; Prognosis

Indexed keywords

E1A ASSOCIATED P300 PROTEIN; MESSENGER RNA;

ADULT; ARTICLE; CANCER CLASSIFICATION; CANCER GROWTH; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; DISTANT METASTASIS; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CARCINOMA; NOSE MUCOSA; OVERALL SURVIVAL; PHARYNX; PHARYNX MUCOSA; PROGRESSION FREE SURVIVAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL; UPREGULATION; WESTERN BLOTTING;

BLOTTING, WESTERN; FEMALE; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; P300-CBP TRANSCRIPTION FACTORS; PROGNOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROC CURVE; SURVIVAL ANALYSIS;

EID: 84861539820     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-10-110     Document Type: Article

References (25)

1. Lo KW, Huang DP. Genetic and epigenetic changes in nasopharyngeal carcinoma. Semin Cancer Biol 2002, 12:451-462. 10.1016/S1044579X02000883, 12450731.
2. Tao Q, Chan AT. Nasopharyngeal carcinoma: molecular pathogenesis and therapeutic developments. Expert Rev Mol Med 2007, 9:1-24.
3. Vasef MA, Ferlito A, Weiss LM. Nasopharyngeal carcinoma, with emphasis on its relationship to Epstein-Barr virus. Ann Otol Rhinol Laryngol 1997, 106:348-356.
4. Kundu TK, Palhan VB, Wang Z, An W, Cole PA, Roeder RG. Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300. Mol Cell 2000, 6:551-561. 10.1016/S1097-2765(00)00054-X, 11030335.
5. Vo N, Goodman RH. CREB-binding protein and p300 in transcriptional regulation. J Biol Chem 2001, 276:13505-13508.
6. Goodman RH, Smolik S. CBP/p300 in cell growth, transformation, and development. Genes Dev 2000, 14:1553-1577.
7. Muraoka M, Konishi M, Kikuchi-Yanoshita R, Tanaka K, Shitara N, Chong JM, Iwama T, Miyaki M. p300 gene alterations in colorectal and gastric carcinomas. Oncogene 1996, 12:1565-1569.
8. Gayther SA, Batley SJ, Linger L, Bannister A, Thorpe K, Chin SF, Daigo Y, Russell P, Wilson A, Sowter HM, et al. Mutations truncating the EP300 acetylase in human cancers. Nat Genet 2000, 24:300-303. 10.1038/73536, 10700188.
9. Fan S, Ma YX, Wang C, Yuan RQ, Meng Q, Wang JA, Erdos M, Goldberg ID, Webb P, Kushner PJ, et al. p300 Modulates the BRCA1 inhibition of estrogen receptor activity. Cancer Res 2002, 62:141-151.
10. Bandyopadhyay D, Okan NA, Bales E, Nascimento L, Cole PA, Medrano EE. Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes. Cancer Res 2002, 62:6231-6239.
11. Li M, Luo RZ, Chen JW, Cao Y, Lu JB, He JH, Wu QL, Cai MY. High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma. J Transl Med 2011, 9:5. 10.1186/1479-5876-9-5, 3022728, 21205329.
12. Vleugel MM, Shvarts D, van der Wall E, van Diest PJ. p300 and p53 levels determine activation of HIF-1 downstream targets in invasive breast cancer. Hum Pathol 2006, 37:1085-1092. 10.1016/j.humpath.2006.03.015, 16867872.
13. Debes JD, Sebo TJ, Lohse CM, Murphy LM, Haugen DA, Tindall DJ. p300 in prostate cancer proliferation and progression. Cancer Res 2003, 63:7638-7640.
14. Isharwal S, Miller MC, Marlow C, Makarov DV, Partin AW, Veltri RW. p300 (histone acetyltransferase) biomarker predicts prostate cancer biochemical recurrence and correlates with changes in epithelia nuclear size and shape. Prostate 2008, 68:1097-1104. 10.1002/pros.20772, 3099408, 18459105.
15. Li Y, Yang HX, Luo RZ, Zhang Y, Li M, Wang X, Jia WH. High expression of p300 has an unfavorable impact on survival in resectable esophageal squamous cell carcinoma. Ann Thorac Sug 2011, 91:1531-1538.
16. Zlobec I, Steele R, Terracciano L, Jass JR, Lugli A. Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancer. J Clin Pathol 2007, 60:1112-1116. 10.1136/jcp.2006.044537, 2014838, 17182662.
17. Cai MY, Zhang B, He WP, Yang GF, Rao HL, Rao ZY, Wu QL, Guan XY, Kung HF, Zeng YX, Xie D. Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma. Cancer Sci 2010, 101:1543-1549. 10.1111/j.1349-7006.2010.01560.x, 20367640.
18. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 1993, 365:855-859. 10.1038/365855a0, 8413673.
19. Ishihama K, Yamakawa M, Semba S, Takeda H, Kawata S, Kimura S, Kimura W. Expression of HDAC1 and CBP/p300 in human colorectal carcinomas. J Clin Pathol 2007, 60:1205-1210. 10.1136/jcp.2005.029165, 2095491, 17720775.
20. Karamouzis MV, Konstantinopoulos PA, Papavassiliou AG. Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis. Cell Res 2007, 17:324-332. 10.1038/cr.2007.10, 17372613.
21. Borrow J, Stanton VP, Andresen JM, Becher R, Behm FG, Chaganti RS, Civin CI, Disteche C, Dube I, Frischauf AM, et al. The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nat Genet 1996, 14:33-41. 10.1038/ng0996-33, 8782817.
22. Kurebayashi J, Otsuki T, Kunisue H, Tanaka K, Yamamoto S, Sonoo H. Expression levels of estrogen receptor-alpha, estrogen receptor-beta, coactivators, and corepressors in breast cancer. Clin Cancer Res 2000, 6:512-518.
23. Fermento ME, Gandini NA, Lang CA, Perez JE, Maturi HV, Curino AC, Facchinetti MM. Intracellular distribution of p300 and its differential recruitment to aggresomes in breast cancer. Exp Mol Pathol 2010, 88:256-264. 10.1016/j.yexmp.2010.01.007, 20097195.
24. De-Carvalho MC, Chimelli LM, Quirico-Santos T. Modulation of fibronectin expression in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis. Braz J Med Biol Res 1999, 32:583-592. 10.1590/S0100-879X1999000500012, 10412570.
25. Hudelist G, Czerwenka K, Kubista E, Marton E, Pischinger K, Singer CF. Expression of sex steroid receptors and their co-factors in normal and malignant breast tissue: AIB1 is a carcinoma-specific co-activator. Breast Cancer Res Treat 2003, 78:193-204. 10.1023/A:1022930710850, 12725419.