The salicylate 1,2-dioxygenase as a model for a conventional gentisate 1,2-dioxygenase: Crystal structures of the G106A mutant and its adducts with gentisate and salicylate

FEBS Journal

Volumn 280, Issue 7, 2013, Pages 1643-1652

  Ferraroni, Marta ^a   Matera, Irene ^a   Bürger, Sibylle ^b   Reichert, Sabrina ^b   Steimer, Lenz ^b   Scozzafava, Andrea ^a   Stolz, Andreas ^b   Briganti, Fabrizio ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF STUTTGART   (Germany)

Author keywords

aromatic catabolism; dioxygenase; ring fission; substrate specificity; X ray crystallography

Indexed keywords

ASPARTIC ACID; DIOXYGENASE; GENTISATE 1,2 DIOXYGENASE; GLYCINE; IRON COMPLEX; SALICYLATE 1,2 DIOXYGENASE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIOXYGENASES; GENTISATES; GLYCINE; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NAPHTHOLS; PHYLLOBACTERIACEAE; PROTEIN CONFORMATION; SALICYLATES; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); CORYNEBACTERIUM GLUTAMICUM; PSEUDAMINOBACTER SALICYLATOXIDANS;

EID: 84875855027     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12173     Document Type: Article

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