A translational approach in using cell sheet fragments of autologous bone marrow-derived mesenchymal stem cells for cellular cardiomyoplasty in a porcine model

Biomaterials

Volumn 34, Issue 19, 2013, Pages 4582-4591

  Huang, Chieh Cheng ^a   Tsai, Hung Wen ^b,c   Lee, Wen Yu ^a   Lin, Wei Wen ^b   Chen, Ding Yuan ^a   Hung, Yi Wen ^b,d   Chen, Jee Wei ^a   Hwang, Shiaw Min ^e   Chang, Yen ^b,c   Sung, Hsing Wen ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^e FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

Author keywords

Arrhythmia; Cardiac tissue regeneration; Cell based therapy; Myocardial infarction; Translational medicine

Indexed keywords

ARRHYTHMIA; BONE MARROW-DERIVED MESENCHYMAL STEM CELLS; CELL-BASED THERAPY; EXTRACELLULAR MATRICES; HISTOLOGICAL ANALYSIS; METHYLCELLULOSE HYDROGEL; MYOCARDIAL INFARCTION; TRANSLATIONAL MEDICINE;

DISEASES; ENDOTHELIAL CELLS; FLOWCHARTING; STEM CELLS;

CELL CULTURE;

METHYLCELLULOSE; SODIUM CHLORIDE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; AUTOLOGOUS MESENCHYMAL STEM CELL TRANSPLANTATION; BONE MARROW; CARDIOMYOPLASTY; CELL DIFFERENTIATION; CELL EXPANSION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; ENGRAFTMENT; EXTRACELLULAR MATRIX; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE; HEART PERFUSION; HEART VENTRICLE; HISTOPATHOLOGY; HUMAN; HYDROGEL; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; NANOFABRICATION; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; SWINE; TRANSLATIONAL RESEARCH;

ANIMALS; ARRHYTHMIAS, CARDIAC; CARDIOMYOPLASTY; CELLS, CULTURED; ECHOCARDIOGRAPHY; HYDROGELS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; METHYLCELLULOSE; MYOCARDIAL INFARCTION; MYOCARDIUM; SWINE; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

SUS;

EID: 84875837259     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.03.003     Document Type: Article

References (34)

1. Laflamme M.A., Murry C.E. Heart regeneration. Nature 2011, 473:326-335.
2. Thal M.A., Krishnamurthy P., Mackie A.R., Hoxha E., Lambers E., Verma S., et al. Enhanced angiogenic and cardiomyocyte differentiation capacity of epigenetically reprogrammed mouse and human endothelial progenitor cells augments their efficacy for ischemic myocardial repair. Circ Res 2012, 111:180-190.
3. Cheng K., Shen D., Smith J., Galang G., Sun B., Zhang J., et al. Transplantation of platelet gel spiked with cardiosphere-derived cells boosts structural and functional benefits relative to gel transplantation alone in rats with myocardial infarction. Biomaterials 2012, 33:2872-2879.
4. Rubart M., Pasumarthi K.B.S., Nakajima H., Soonpaa M.H., Nakajima H.O., Field L.J. Physiological coupling of donor and host cardiomyocytes after cellular transplantation. Circ Res 2003, 92:1217-1224.
5. Tsuji H., Miyoshi S., Ikegami Y., Hida N., Asada H., Togashi I., et al. Xenografted human amniotic membrane-derived mesenchymal stem cells are immunologically tolerated and transdifferentiated into cardiomyocytes. Circ Res 2010, 106:1613-1623.
6. Williams A.R., Hare J.M. Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease. Circ Res 2011, 109:923-940.
7. Zhao Y., Zhang S., Zhou J., Wang J., Zhen M., Liu Y., et al. The development of a tissue-engineered artery using decellularized scaffold and autologous ovine mesenchymal stem cells. Biomaterials 2010, 31:296-307.
8. Ye Z., Zhou Y., Cai H., Tan W. Myocardial regeneration: roles of stem cells and hydrogels. Adv Drug Deliv Rev 2011, 63:688-697.
9. Korf-Klingebiel M., Kempf T., Sauer T., Brinkmann E., Fischer P., Meyer G.P., et al. Bone marrow cells are a rich source of growth factors and cytokines: implications for cell therapy trials after myocardial infarction. Eur Heart J 2008, 29:2851-2858.
10. Wang C.C., Chen C.H., Lin W.W., Hwang S.M., Hsieh P.C.H., Lai P.H., et al. Direct intramyocardial injection of mesenchymal stem cell sheet fragments improves cardiac functions after infarction. Cardiovasc Res 2008, 77:515-524.
11. Wang F., Guan J. Cellular cardiomyoplasty and cardiac tissue engineering for myocardial therapy. Adv Drug Deliv Rev 2010, 62:784-797.
12. Bouten C.V.C., Dankers P.Y.W., Driessen-Mol A., Pedron S., Brizard A.M.A., Baaijens F.P.T. Substrates for cardiovascular tissue engineering. Adv Drug Deliv Rev 2011, 63:221-241.
13. Hwang N.S., Varghese S., Elisseeff J. Controlled differentiation of stem cells. Adv Drug Deliv Rev 2008, 60:199-214.
14. de Mel A., Jell G., Stevens M.M., Seifalian A.M. Biofunctionalization of biomaterials for accelerated in situ endothelialization: a review. Biomacromolecules 2008, 9:2969-2979.
15. Lee W.Y., Wei H.J., Lin W.W., Yeh Y.C., Hwang S.M., Wang J.J., et al. Enhancement of cell retention and functional benefits in myocardial infarction using human amniotic-fluid stem-cell bodies enriched with endogenous ECM. Biomaterials 2011, 32:5558-5567.
16. Christman K.L., Lee R.J. Biomaterials for the treatment of myocardial infarction. J Am Coll Cardiol 2006, 48:907-913.
17. Yeh Y.C., Lee W.Y., Yu C.L., Hwang S.M., Chung M.F., Hsu L.W., et al. Cardiac repair with injectable cell sheet fragments of human amniotic fluid stem cells in an immune-suppressed rat model. Biomaterials 2010, 31:6444-6453.
18. Chen C.H., Chang Y., Wang C.C., Huang C.H., Huang C.C., Yeh Y.C., et al. Construction and characterization of fragmented mesenchymal-stem-cell sheets for intramuscular injection. Biomaterials 2007, 28:4643-4651.
19. Chen C.H., Tsai C.C., Chen W., Mi F.L., Liang H.F., Chen S.C., et al. Novel living cell sheet harvest system composed of thermoreversible methylcellulose hydrogels. Biomacromolecules 2006, 7:736-743.
20. Gu M., Nguyen P.K., Lee A.S., Xu D., Hu S., Plews J., et al. Microfluidic single cell analysis show porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation. Circ Res 2012, 111:880-893.
21. Dixon J.A., Spinale F.G. Large animal models of heart failure: a critical link in the translation of basic science to clinical practice. Circ Heart Fail 2009, 2:262-271.
22. Meyerrose T., Olson S., Pontow S., Kalomoiris S., Jung Y., Annett G., et al. Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors. Adv Drug Deliv Rev 2010, 62:1167-1174.
23. Zhou W., Han C., Song Y., Yan X., Li D., Chai Z., et al. The performance of bone marrow mesenchymal stem cell - implant complexes prepared by cell sheet engineering techniques. Biomaterials 2010, 31:3212-3221.
24. Smith R.R., Barile L., Messina E., Marbán E. Stem cells in the heart: what's the buzz all about? Part 2: arrhythmic risks and clinical studies. Heart Rhythm 2008, 5:880-887.
25. Coppen S.R., Fukushima S., Shintani Y., Takahashi K., Varela-Carver A., Salem H., et al. A factor underlying late-phase arrhythmogenicity after cell therapy to the heart: global downregulation of connexin43 in the host myocardium after skeletal myoblast transplantation. Circulation 2008, 118:S138-S144.
26. Bloch Thomsen P.E., Jons C., Raatikainen M.J.P., Moerch Joergensen R., Hartikainen J., Virtanen V., et al. Long-term recording of cardiac arrhythmias with an implantable cardiac monitor in patients with reduced ejection fraction after acute myocardial infarction: the cardiac arrhythmias and risk stratification after acute myocardial infarction (CARISMA) study. Circulation 2010, 122:1258-1264.
27. Canty J.M., Suzuki G., Banas M.D., Verheyen F., Borgers M., Fallavollita J.A. Hibernating myocardium: chronically adapted to ischemia but vulnerable to sudden death. Circ Res 2004, 94:1142-1149.
28. Lin Y.D., Yeh M.L., Yang Y.J., Tsai D.C., Chu T.Y., Shih Y.Y., et al. Intramyocardial peptide nanofiber injection improves postinfarction ventricular remodeling and efficacy of bone marrow cell therapy in pigs. Circulation 2010, 122:S132-S141.
29. Cheng K., Blusztajn A., Shen D., Li T.S., Sun B., Galang G., et al. Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel. Biomaterials 2012, 33:5317-5324.
30. Tang X.L., Rokosh G., Sanganalmath S.K., Yuan F., Sato H., Mu J., et al. Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction. Circulation 2010, 121:293-305.
31. Hsiao F.S.H., Lian W.S., Lin S.P., Lin C.J., Lin Y.S., Cheng E.C.H., et al. Toward an ideal animal model to trace donor cell fates after stem cell therapy: production of stably labeled multipotent mesenchymal stem cells from bone marrow of transgenic pigs harboring enhanced green fluorescence protein gene. J Anim Sci 2011, 89:3460-3472.
32. Chen J., Lu Z., Cheng D., Peng S., Wang H. Isolation and characterization of porcine amniotic fluid-derived multipotent stem cells. PLoS ONE 2011, 6:e19964.
33. Guan J., Wang F., Li Z., Chen J., Guo X., Liao J., et al. The stimulation of the cardiac differentiation of mesenchymal stem cells in tissue constructs that mimic myocardium structure and biomechanics. Biomaterials 2011, 32:5568-5580.
34. Davani S., Marandin A., Mersin N., Royer B., Kantelip B., Hervé P., et al. Mesenchymal progenitor cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a rat cellular cardiomyoplasty model. Circulation 2003, 108(Suppl. 1):II253-II258.