Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation

Circulation Research

Volumn 111, Issue 7, 2012, Pages 882-893

  Gu, Mingxia ^a,b   Nguyen, Patricia K ^a   Lee, Andrew S ^a   Xu, Dan ^a   Hu, Shijun ^a   Plews, Jordan R ^a   Han, Leng ^a   Huber, Bruno C ^a   Lee, Won Hee ^a   Gong, Yongquan ^a,c   De Almeida, Patricia E ^a   Lyons, Jennifer ^a   Ikeno, Fumi ^a   Pacharinsak, Cholawat ^c   Connolly, Andrew J ^c   Gambhir, Sanjiv S ^a   Robbins, Robert C ^c   Longaker, Michael T ^c,e   Wu, Joseph C ^a,d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c STANFORD UNIVERSITY   (United States)

^d Stanford California and Cofounder   (United States)

^e NONE   (United States)

Author keywords

induced pluripotent stem cells; ischemic heart disease; large animal models; molecular imaging; myocardial infarction; paracrine activation; vascular biology

Indexed keywords

ADIPOSE TISSUE CELL; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CELL FUNCTION; CELL POPULATION; CELL SURVIVAL; CELL THERAPY; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; HEART EJECTION FRACTION; HEART FUNCTION; HEART MUSCLE; HEART MUSCLE ISCHEMIA; IMMUNOHISTOCHEMISTRY; MICROARRAY ANALYSIS; MICROFLUIDIC ANALYSIS; MORPHOLOGY; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARACRINE SIGNALING; PLURIPOTENT STEM CELL; POLYMERASE CHAIN REACTION; PORCINE ADENOVIRUS; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SINGLE CELL ANALYSIS; STROMA CELL; TREATMENT RESPONSE;

EID: 84866538756     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.269001     Document Type: Article

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