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Volumn 154, Issue 4, 2013, Pages 1565-1576

Ghrelin restoration of function in vitro in somatotropes from male mice lacking the janus kinase (JAK)-binding site of the leptin receptor

Author keywords

[No Author keywords available]

Indexed keywords

GHRELIN; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; JANUS KINASE; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA;

EID: 84875831728     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-2254     Document Type: Article
Times cited : (15)

References (43)
  • 1
    • 0026780758 scopus 로고
    • The impact of gonadal steroid hormone action on growth hormone secretion during childhood and adolescence
    • Kerrigan JR, Rogol AD. The impact of gonadal steroid hormone action on growth hormone secretion during childhood and adolescence. Endocr Rev. 1992;13:281-298.
    • (1992) Endocr Rev , vol.13 , pp. 281-298
    • Kerrigan, J.R.1    Rogol, A.D.2
  • 2
    • 33645517241 scopus 로고    scopus 로고
    • Somatotropic and gonadotropic axes linkages in infancy, childhood, and the puberty-adult transition
    • Veldhuis JD, Roemmich JN, Richmond EJ, Bowers CY. Somatotropic and gonadotropic axes linkages in infancy, childhood, and the puberty-adult transition. Endocr Rev. 2006;27:101-140.
    • (2006) Endocr Rev , vol.27 , pp. 101-140
    • Veldhuis, J.D.1    Roemmich, J.N.2    Richmond, E.J.3    Bowers, C.Y.4
  • 3
    • 13444274286 scopus 로고    scopus 로고
    • Endocrine control of body composition in infancy, childhood, and puberty
    • Veldhuis JD, Roemmich JN, Richmond EJ, et al. Endocrine control of body composition in infancy, childhood, and puberty. Endocr Rev. 2005;26:114-146.
    • (2005) Endocr Rev , vol.26 , pp. 114-146
    • Veldhuis, J.D.1    Roemmich, J.N.2    Richmond, E.J.3
  • 4
    • 78650835266 scopus 로고    scopus 로고
    • The somatotrope as a metabolic sensor: Deletion of leptin receptors causes obesity
    • Childs GV, Akhter N, Haney A, et al. The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity. Endocrinology. 2011;152:69-81.
    • (2011) Endocrinology , vol.152 , pp. 69-81
    • Childs, G.V.1    Akhter, N.2    Haney, A.3
  • 5
    • 33846447066 scopus 로고    scopus 로고
    • Leptin antagonist reveals an uncoupling between leptin receptor STAT3 signaling and metabolic responses with central leptin resistance
    • Scarpace PJ, Matheny M, Zhang Y, Cheng KY, Tumer N. Leptin antagonist reveals an uncoupling between leptin receptor STAT3 signaling and metabolic responses with central leptin resistance. J Pharmacol Exp Ther. 2007;320:706-712.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 706-712
    • Scarpace, P.J.1    Matheny, M.2    Zhang, Y.3    Cheng, K.Y.4    Tumer, N.5
  • 6
    • 33846446839 scopus 로고    scopus 로고
    • Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food following high-fat feeding are leptin dependent
    • Zhang J, Matheny MK, Tumer N, Mitchell MK, Scarpace PJ. Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food following high-fat feeding are leptin dependent. Am J Physiol Regul Integr Comp Physiol. 2007;292:R868-R874.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292
    • Zhang, J.1    Matheny, M.K.2    Tumer, N.3    Mitchell, M.K.4    Scarpace, P.J.5
  • 7
    • 27844558280 scopus 로고    scopus 로고
    • Dehydroepiandrosterone restoration of growth hormone gene expression in aging female rats, in vivo and in vitro: Evidence for actions via estrogen receptors
    • Iruthayanathan M, Zhou YH, Childs GV. Dehydroepiandrosterone restoration of growth hormone gene expression in aging female rats, in vivo and in vitro: evidence for actions via estrogen receptors. Endocrinology. 2005;146:5176-5187.
    • (2005) Endocrinology , vol.146 , pp. 5176-5187
    • Iruthayanathan, M.1    Zhou, Y.H.2    Childs, G.V.3
  • 8
    • 0032983417 scopus 로고    scopus 로고
    • Interaction between leptin and growth hormone (GH)/IGF-I axis
    • Isozaki O, Tsushima T, Miyakawa M, Demura H, Seki H. Interaction between leptin and growth hormone (GH)/IGF-I axis. Endocr J. 1999;46(Suppl):S17-S24.
    • (1999) Endocr J , vol.46 , Issue.SUPPL.
    • Isozaki, O.1    Tsushima, T.2    Miyakawa, M.3    Demura, H.4    Seki, H.5
  • 10
    • 33244492641 scopus 로고    scopus 로고
    • Estrogen mediated cross talk between the ovary and pituitary somatotrope. Pre-ovulatory support for reproductive activity
    • Childs GV, Iruthayanathan M, Akhter N, Johnson BW. Estrogen mediated cross talk between the ovary and pituitary somatotrope. Pre-ovulatory support for reproductive activity. Mol Cell Endocrinol. 2006;247:60-63.
    • (2006) Mol Cell Endocrinol , vol.247 , pp. 60-63
    • Childs, G.V.1    Iruthayanathan, M.2    Akhter, N.3    Johnson, B.W.4
  • 12
    • 33947140909 scopus 로고    scopus 로고
    • Effects of leptin replacement on hypothalamic-pituitary growth hormone axis function and circulating ghrelin levels in ob/ob mice
    • Luque RM, Huang ZH, Shah B, Mazzone T, Kineman RD. Effects of leptin replacement on hypothalamic-pituitary growth hormone axis function and circulating ghrelin levels in ob/ob mice. Am J Physiol Endocrinol Metab. 2007;292:E891-E899.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Luque, R.M.1    Zh, H.2    Shah, B.3    Mazzone, T.4    Kineman, R.D.5
  • 13
    • 0033679813 scopus 로고    scopus 로고
    • Leptin regulates pulsatile luteinizing hormone and growth hormone secretion in the sheep
    • Nagatani S, Zeng Y, Keisler DH, Foster DL, Jaffe CA. Leptin regulates pulsatile luteinizing hormone and growth hormone secretion in the sheep. Endocrinology. 2000;141:3965-3975.
    • (2000) Endocrinology , vol.141 , pp. 3965-3975
    • Nagatani, S.1    Zeng, Y.2    Keisler, D.H.3    Foster, D.L.4    Jaffe, C.A.5
  • 14
    • 0032739022 scopus 로고    scopus 로고
    • Neuroendocrine regulation and actions of leptin
    • Casanueva FF, Dieguez C. Neuroendocrine Regulation and Actions of Leptin. Front Neuroendocrinol. 1999;20:317-363.
    • (1999) Front Neuroendocrinol , vol.20 , pp. 317-363
    • Casanueva, F.F.1    Dieguez, C.2
  • 15
    • 0035076198 scopus 로고    scopus 로고
    • The in vitro effect of leptin on growth hormone secretion from primary cultured ovine somatotrophs
    • Chen C, Roh SG, Nie GY, et al. The in vitro effect of leptin on growth hormone secretion from primary cultured ovine somatotrophs. Endocrine. 2001;14:73-78.
    • (2001) Endocrine , vol.14 , pp. 73-78
    • Chen, C.1    Roh, S.G.2    Nie, G.Y.3
  • 16
    • 0035210714 scopus 로고    scopus 로고
    • Direct modification of somatotrope function by long-term leptin treatment of primary cultured ovine pituitary cells
    • Roh SG, Nie GY, Loneragan K, Gertler A, Chen C. Direct modification of somatotrope function by long-term leptin treatment of primary cultured ovine pituitary cells. Endocrinology. 2001;142: 5167-5171.
    • (2001) Endocrinology , vol.142 , pp. 5167-5171
    • Roh, S.G.1    Nie, G.Y.2    Loneragan, K.3    Gertler, A.4    Chen, C.5
  • 17
    • 0032603721 scopus 로고    scopus 로고
    • Regulation of growth hormone secretion by signals produced by the adipose tissue
    • Pombo M, Pombo CM, Astorga R, et al. Regulation of growth hormone secretion by signals produced by the adipose tissue. J Endocrinol Invest. 1999;22:22-26.
    • (1999) J Endocrinol Invest , vol.22 , pp. 22-26
    • Pombo, M.1    Pombo, C.M.2    Astorga, R.3
  • 18
    • 0031764737 scopus 로고    scopus 로고
    • Intact leptin receptor is selectively expressed in human fetal pituitary and pituitary adenomas and signals human fetal pituitary growth hormone secretion
    • Shimon I, Yan X, Magoffin DA, Friedman TC, Melmed S. Intact leptin receptor is selectively expressed in human fetal pituitary and pituitary adenomas and signals human fetal pituitary growth hormone secretion. J Clin Endocrinol Metab. 1998;83:4059-4064.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 4059-4064
    • Shimon, I.1    Yan, X.2    Magoffin, D.A.3    Friedman, T.C.4    Melmed, S.5
  • 19
    • 0036155743 scopus 로고    scopus 로고
    • Leptin regulates GH gene expression and secretion and nitric oxide production in pig pituitary cells
    • Baratta M, Saleri R, Mainardi GL, Valle D, Giustina A, Tamanini C. Leptin regulates GH gene expression and secretion and nitric oxide production in pig pituitary cells. Endocrinology. 2002;143: 551-557.
    • (2002) Endocrinology , vol.143 , pp. 551-557
    • Baratta, M.1    Saleri, R.2    Mainardi, G.L.3    Valle, D.4    Giustina, A.5    Tamanini, C.6
  • 20
    • 0036401449 scopus 로고    scopus 로고
    • In vitro effect of human recombinant leptin and expression of leptin receptors on growth hormonesecreting human pituitary adenomas
    • Giusti M, Bocca L, Florio T, et al. In vitro effect of human recombinant leptin and expression of leptin receptors on growth hormonesecreting human pituitary adenomas. Clin Endocrinol (Oxf). 2002; 57:449-455.
    • (2002) Clin Endocrinol (Oxf) , vol.57 , pp. 449-455
    • Giusti, M.1    Bocca, L.2    Florio, T.3
  • 21
    • 2542609914 scopus 로고    scopus 로고
    • Leptin stimulates growth hormone secretion via a direct pituitary effect combined with a decreased somatostatin tone in a median eminence-pituitary perifusion study
    • Saleri R, Giustina A, Tamanini C, et al. Leptin stimulates growth hormone secretion via a direct pituitary effect combined with a decreased somatostatin tone in a median eminence-pituitary perifusion study. Neuroendocrinology. 2004;79:221-228.
    • (2004) Neuroendocrinology , vol.79 , pp. 221-228
    • Saleri, R.1    Giustina, A.2    Tamanini, C.3
  • 22
    • 19944408618 scopus 로고    scopus 로고
    • Effects of different culture conditions and leptin onGHmRNAexpression andGHsecretion by pig pituitary cells
    • Saleri R, Grasselli F, Tamanini C. Effects of different culture conditions and leptin onGHmRNAexpression andGHsecretion by pig pituitary cells. Horm Metab Res. 2005;37:214-219.
    • (2005) Horm Metab Res , vol.37 , pp. 214-219
    • Saleri, R.1    Grasselli, F.2    Tamanini, C.3
  • 23
    • 0033205510 scopus 로고    scopus 로고
    • Leptin stimulates basal and GHRH-induced GH release from cultured rat anterior pituitary cells in vitro
    • Mizuno I, Okimura Y, Takahashi Y, Kaji H, Abe H, Chihara K. Leptin stimulates basal and GHRH-induced GH release from cultured rat anterior pituitary cells in vitro. Kobe J Med Sci. 1999;45: 221-227.
    • (1999) Kobe J Med Sci , vol.45 , pp. 221-227
    • Mizuno, I.1    Okimura, Y.2    Takahashi, Y.3    Kaji, H.4    Abe, H.5    Chihara, K.6
  • 24
    • 0043172273 scopus 로고    scopus 로고
    • Effects of leptin on basal and GHRH-stimulated GH secretion from the bovine adenohypophysis are dependent upon nutritional status
    • Zieba DA, Amstalden M, Morton S, et al. Effects of leptin on basal and GHRH-stimulated GH secretion from the bovine adenohypophysis are dependent upon nutritional status. J Endocrinol. 2003; 178:83-89.
    • (2003) J Endocrinol , vol.178 , pp. 83-89
    • Zieba, D.A.1    Amstalden, M.2    Morton, S.3
  • 25
    • 34548731413 scopus 로고    scopus 로고
    • Fasting and glucose effects on pituitary leptin expression: Is leptin a local signal for nutrient status?
    • Crane C, Akhter N, Johnson BW, et al. Fasting and glucose effects on pituitary leptin expression: is leptin a local signal for nutrient status? J Histochem Cytochem. 2007;55:1059-1074.
    • (2007) J Histochem Cytochem , vol.55 , pp. 1059-1074
    • Crane, C.1    Akhter, N.2    Johnson, B.W.3
  • 26
    • 9444264702 scopus 로고    scopus 로고
    • LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin
    • Bates SH, Dundon TA, Seifert M, Carlson M, Maratos-Flier E, MyersMGJr. LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin. Diabetes. 2004;53: 3067-3073.
    • (2004) Diabetes , vol.53 , pp. 3067-3073
    • Bates, S.H.1    Dundon, T.A.2    Seifert, M.3    Carlson, M.4    Maratos-Flier, E.5    Myers Jr., M.G.6
  • 27
    • 0345168238 scopus 로고    scopus 로고
    • The role of leptin receptor signaling in feeding and neuroendocrine function
    • Bates SH, Myers MG Jr. The role of leptin receptor signaling in feeding and neuroendocrine function. Trends Endocrinol Metab. 2003;14:447-452.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 447-452
    • Bates, S.H.1    Myers Jr., M.G.2
  • 28
    • 0037456304 scopus 로고    scopus 로고
    • STAT3 signalling is required for leptin regulation of energy balance but not reproduction
    • Bates SH, Stearns WH, Dundon TA, et al. STAT3 signalling is required for leptin regulation of energy balance but not reproduction. Nature. 2003;421:856-859.
    • (2003) Nature , vol.421 , pp. 856-859
    • Bates, S.H.1    Stearns, W.H.2    Dundon, T.A.3
  • 30
    • 0032032575 scopus 로고    scopus 로고
    • Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function
    • Ahima RS, Prabakaran D, Flier JS. Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function. J Clin Invest. 1998;101:1020-1027.
    • (1998) J Clin Invest , vol.101 , pp. 1020-1027
    • Ahima, R.S.1    Prabakaran, D.2    Flier, J.S.3
  • 31
    • 85046979811 scopus 로고    scopus 로고
    • Postnatal leptin is necessary for maturation of numerous organs in newborn rats
    • Attig L, Larcher T, Gertler A, Abdennebi-Najar L, Djiane J. Postnatal leptin is necessary for maturation of numerous organs in newborn rats. Organogenesis. 2011;7:88-94.
    • (2011) Organogenesis , vol.7 , pp. 88-94
    • Attig, L.1    Larcher, T.2    Gertler, A.3    Abdennebi-Najar, L.4    Djiane, J.5
  • 32
    • 0032775416 scopus 로고    scopus 로고
    • Differential expression of gonadotropin and prolactin antigens by GHRH target cells from male and female rats
    • Childs GV, Unabia G, Miller BT, Collins TJ. Differential expression of gonadotropin and prolactin antigens by GHRH target cells from male and female rats. J Endocrinol. 1999;162:177-187.
    • (1999) J Endocrinol , vol.162 , pp. 177-187
    • Childs, G.V.1    Unabia, G.2    Miller, B.T.3    Collins, T.J.4
  • 33
    • 84866760009 scopus 로고    scopus 로고
    • Ablation of leptin signaling to somatotropes: Changes in metabolic factors that cause obesity
    • Akhter N, Odle AK, Allensworth-James ML, et al. Ablation of leptin signaling to somatotropes: changes in metabolic factors that cause obesity. Endocrinology. 2012;153:4705-4715.
    • (2012) Endocrinology , vol.153 , pp. 4705-4715
    • Akhter, N.1    Odle, A.K.2    Allensworth-James, M.L.3
  • 34
    • 0344394262 scopus 로고    scopus 로고
    • Intracellular signaling mechanisms mediating ghrelin-stimulated growth hormone release in somatotropes
    • Malagon MM, Luque RM, Ruiz-Guerrero E, et al. Intracellular signaling mechanisms mediating ghrelin-stimulated growth hormone release in somatotropes. Endocrinology. 2003;144:5372-5380.
    • (2003) Endocrinology , vol.144 , pp. 5372-5380
    • Malagon, M.M.1    Luque, R.M.2    Ruiz-Guerrero, E.3
  • 36
    • 1842480284 scopus 로고    scopus 로고
    • Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
    • Sun Y, Wang P, Zheng H, Smith RG. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci USA. 2004;101: 4679-4684.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4679-4684
    • Sun, Y.1    Wang, P.2    Zheng, H.3    Smith, R.G.4
  • 37
    • 0037453209 scopus 로고    scopus 로고
    • The role of circulating ghrelin in growth hormone (GH) secretion in freely moving male rats
    • Okimura Y, Ukai K, Hosoda H, et al. The role of circulating ghrelin in growth hormone (GH) secretion in freely moving male rats. Life Sci. 2003;72:2517-2524.
    • (2003) Life Sci , vol.72 , pp. 2517-2524
    • Okimura, Y.1    Ukai, K.2    Hosoda, H.3
  • 38
    • 0033990083 scopus 로고    scopus 로고
    • In situ hybridization with nonradioactive probes
    • Childs GV. In situ hybridization with nonradioactive probes. Methods Mol Biol. 2000;123:131-141.
    • (2000) Methods Mol Biol , vol.123 , pp. 131-141
    • Childs, G.V.1
  • 39
    • 0034457323 scopus 로고    scopus 로고
    • Differential expression of growth hormone messenger ribonucleic acid by somatotropes and gonadotropes in male and cycling female rats
    • Childs GV, Unabia G, Wu P. Differential expression of growth hormone messenger ribonucleic acid by somatotropes and gonadotropes in male and cycling female rats. Endocrinology. 2000;141: 1560-1570.
    • (2000) Endocrinology , vol.141 , pp. 1560-1570
    • Childs, G.V.1    Unabia, G.2    Wu, P.3
  • 40
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 1999;402:656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 41
    • 0035320623 scopus 로고    scopus 로고
    • Ghrelin: Discovery of the natural endogenous ligand for the growth hormone secretagogue receptor
    • Kojima M, Hosoda H, Matsuo H, Kangawa K. Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor. Trends Endocrinol Metab. 2001;12:118-122.
    • (2001) Trends Endocrinol Metab , vol.12 , pp. 118-122
    • Kojima, M.1    Hosoda, H.2    Matsuo, H.3    Kangawa, K.4
  • 42
    • 3843104682 scopus 로고    scopus 로고
    • The role of pituitary ghrelin in growth hormone (GH) secretion: GH-releasing hormone-dependent regulation of pituitary ghrelin gene expression and peptide content
    • Kamegai J, Tamura H, Shimizu T, et al. The role of pituitary ghrelin in growth hormone (GH) secretion: GH-releasing hormone-dependent regulation of pituitary ghrelin gene expression and peptide content. Endocrinology. 2004;145:3731-3738.
    • (2004) Endocrinology , vol.145 , pp. 3731-3738
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3
  • 43
    • 18844375807 scopus 로고    scopus 로고
    • Endogenous circulating ghrelin does not mediate growth hormone rhythmicity or response to fasting
    • Avram AM, Jaffe CA, Symons KV, Barkan AL. Endogenous circulating ghrelin does not mediate growth hormone rhythmicity or response to fasting. J Clin Endocrinol Metab. 2005;90:2982-2987.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2982-2987
    • Avram, A.M.1    Jaffe, C.A.2    Symons, K.V.3    Barkan, A.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.