Fas/CD95-Induced Chemokines Can Serve as " Find-Me" Signals for Apoptotic Cells

Molecular Cell

Volumn 49, Issue 6, 2013, Pages 1034-1048

  Cullen, Sean P ^a   Henry, Conor M ^a   Kearney, Conor J ^a   Logue, Susan E ^a   Feoktistova, Maria ^b   Tynan, Graham A ^a   Lavelle, Ed C ^a   Leverkus, Martin ^b   Martin, Seamus J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; FAS ANTIBODY; FAS LIGAND; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHAGOCYTE; PROTEIN EXPRESSION;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CASPASE 8; CHEMOKINE CCL2; CHEMOKINES; CHEMOTAXIS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; INFLAMMATION MEDIATORS; INHIBITOR OF APOPTOSIS PROTEINS; INTERLEUKIN-8; MICE; MICE, INBRED C57BL; NF-KAPPA B; PHAGOCYTES; PROTEIN BINDING; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

INTRACISTERNAL A-PARTICLES;

EID: 84875809939     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2013.01.025     Document Type: Article

References (35)

1. Allison J., Georgiou H.M., Strasser A., Vaux D.L. Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts. Proc. Natl. Acad. Sci. USA 1997, 94:3943-3947.
2. Altemeier W.A., Zhu X., Berrington W.R., Harlan J.M., Liles W.C. Fas (CD95) induces macrophage proinflammatory chemokine production via a MyD88-dependent, caspase-independent pathway. J. Leukoc. Biol. 2007, 82:721-728.
3. Barnhart B.C., Legembre P., Pietras E., Bubici C., Franzoso G., Peter M.E. CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells. EMBO J. 2004, 23:3175-3185.
4. Berg D., Stühmer T., Siegmund D., Müller N., Giner T., Dittrich-Breiholz O., Kracht M., Bargou R., Wajant H. Oligomerized tumor necrosis factor-related apoptosis inducing ligand strongly induces cell death in myeloma cells, but also activates proinflammatory signaling pathways. FEBS J. 2009, 276:6912-6927.
5. Brennan F.M., McInnes I.B. Evidence that cytokines play a role in rheumatoid arthritis. J. Clin. Invest. 2008, 118:3537-3545.
6. Chekeni F.B., Elliott M.R., Sandilos J.K., Walk S.F., Kinchen J.M., Lazarowski E.R., Armstrong A.J., Penuela S., Laird D.W., Salvesen G.S., et al. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature 2010, 467:863-867.
7. Chen L., Park S.M., Tumanov A.V., Hau A., Sawada K., Feig C., Turner J.R., Fu Y.X., Romero I.L., Lengyel E., Peter M.E. CD95 promotes tumour growth. Nature 2010, 465:492-496.
8. Choi C., Xu X., Oh J.W., Lee S.J., Gillespie G.Y., Park H., Jo H., Benveniste E.N. Fas-induced expression of chemokines in human glioma cells: involvement of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase. Cancer Res. 2001, 61:3084-3091.
9. Croft M., Duan W., Choi H., Eun S.Y., Madireddi S., Mehta A. TNF superfamily in inflammatory disease: translating basic insights. Trends Immunol. 2012, 33:144-152.
10. Dynek J.N., Goncharov T., Dueber E.C., Fedorova A.V., Izrael-Tomasevic A., Phu L., Helgason E., Fairbrother W.J., Deshayes K., Kirkpatrick D.S., Vucic D. c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling. EMBO J. 2010, 29:4198-4209.
11. Elliott M.R., Chekeni F.B., Trampont P.C., Lazarowski E.R., Kadl A., Walk S.F., Park D., Woodson R.I., Ostankovich M., Sharma P., et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 2009, 461:282-286.
12. Farley S.M., Dotson A.D., Purdy D.E., Sundholm A.J., Schneider P., Magun B.E., Iordanov M.S. Fas ligand elicits a caspase-independent proinflammatory response in human keratinocytes: implications for dermatitis. J. Invest. Dermatol. 2006, 126:2438-2451.
13. Geserick P., Hupe M., Moulin M., Wong W.W., Feoktistova M., Kellert B., Gollnick H., Silke J., Leverkus M. Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment. J. Cell Biol. 2009, 187:1037-1054.
14. Gregory C.D., Pound J.D. Cell death in the neighbourhood: direct microenvironmental effects of apoptosis in normal and neoplastic tissues. J. Pathol. 2011, 223:177-194.
15. Gude D.R., Alvarez S.E., Paugh S.W., Mitra P., Yu J., Griffiths R., Barbour S.E., Milstien S., Spiegel S. Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a " come-and-get-me" signal. FASEB J. 2008, 22:2629-2638.
16. Guo Z., Zhang M., Tang H., Cao X. Fas signal links innate and adaptive immunity by promoting dendritic-cell secretion of CC and CXC chemokines. Blood 2005, 106:2033-2041.
17. Haas T.L., Emmerich C.H., Gerlach B., Schmukle A.C., Cordier S.M., Rieser E., Feltham R., Vince J., Warnken U., Wenger T., et al. Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol. Cell 2009, 36:831-844.
18. Hsu H., Huang J., Shu H.B., Baichwal V., Goeddel D.V. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 1996, 4:387-396.
19. Kang S.M., Schneider D.B., Lin Z., Hanahan D., Dichek D.A., Stock P.G., Baekkeskov S. Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction. Nat. Med. 1997, 3:738-743.
20. Kleber S., Sancho-Martinez I., Wiestler B., Beisel A., Gieffers C., Hill O., Thiemann M., Mueller W., Sykora J., Kuhn A., et al. Yes and PI3K bind CD95 to signal invasion of glioblastoma. Cancer Cell 2008, 13:235-248.
21. Lauber K., Bohn E., Kröber S.M., Xiao Y.J., Blumenthal S.G., Lindemann R.K., Marini P., Wiedig C., Zobywalski A., Baksh S., et al. Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. Cell 2003, 113:717-730.
22. Lavrik I.N., Krammer P.H. Regulation of CD95/Fas signaling at the DISC. Cell Death Differ. 2012, 19:36-41.
23. Matzinger P. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 1994, 12:991-1045.
24. Obeid M., Tesniere A., Ghiringhelli F., Fimia G.M., Apetoh L., Perfettini J.L., Castedo M., Mignot G., Panaretakis T., Casares N., et al. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat. Med. 2007, 13:54-61.
25. Park D.R., Thomsen A.R., Frevert C.W., Pham U., Skerrett S.J., Kiener P.A., Liles W.C. Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages. J. Immunol. 2003, 170:6209-6216.
26. Petersen S.L., Wang L., Yalcin-Chin A., Li L., Peyton M., Minna J., Harran P., Wang X. Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell 2007, 12:445-456.
27. Ravichandran K.S. Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways. Immunity 2011, 35:445-455.
28. Rescigno M., Piguet V., Valzasina B., Lens S., Zubler R., French L., Kindler V., Tschopp J., Ricciardi-Castagnoli P. Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL)-1beta, and the production of interferon gamma in the absence of IL-12 during DC-T cell cognate interaction: a new role for Fas ligand in inflammatory responses. J. Exp. Med. 2000, 192:1661-1668.
29. Schaub F.J., Han D.K., Liles W.C., Adams L.D., Coats S.A., Ramachandran R.K., Seifert R.A., Schwartz S.M., Bowen-Pope D.F. Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells. Nat. Med. 2000, 6:790-796.
30. Shimizu M., Yoshimoto T., Sato M., Morimoto J., Matsuzawa A., Takeda Y. Roles of CXC chemokines and macrophages in the recruitment of inflammatory cells and tumor rejection induced by Fas/Apo-1 (CD95) ligand-expressing tumor. Int. J. Cancer 2005, 114:926-935.
31. Strasser A., Jost P.J., Nagata S. The many roles of FAS receptor signaling in the immune system. Immunity 2009, 30:180-192.
32. Varfolomeev E., Maecker H., Sharp D., Lawrence D., Renz M., Vucic D., Ashkenazi A. Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. J. Biol. Chem. 2005, 280:40599-40608.
33. Varfolomeev E., Blankenship J.W., Wayson S.M., Fedorova A.V., Kayagaki N., Garg P., Zobel K., Dynek J.N., Elliott L.O., Wallweber H.J., et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007, 131:669-681.
34. Vince J.E., Wong W.W., Khan N., Feltham R., Chau D., Ahmed A.U., Benetatos C.A., Chunduru S.K., Condon S.M., McKinlay M., et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007, 131:682-693.
35. Wallach D., Varfolomeev E.E., Malinin N.L., Goltsev Y.V., Kovalenko A.V., Boldin M.P. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu. Rev. Immunol. 1999, 17:331-367.