A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 63, Issue 2, 2007, Pages 78-83

  Yap, Thai Leong ^a,b   Chen, Yen Liang ^a   Xu, Ting ^a   Wen, Daying ^a   Vasudevan, Subhash G ^a   Lescar, Julien ^a,b  

^a NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Dengue; Flaviviruses; RNA dependent RNA polymerases

Indexed keywords

CHLORIDE; DIVALENT CATION; MAGNESIUM CHLORIDE; MANGANESE CHLORIDE; MANGANESE DERIVATIVE; RNA DIRECTED RNA POLYMERASE; VIRUS PROTEIN;

ARTICLE; CATALYSIS; CHEMISTRY; CRYSTALLIZATION; DENGUE VIRUS; ENZYMOLOGY; ION EXCHANGE CHROMATOGRAPHY; ISOLATION AND PURIFICATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

CATALYSIS; CATIONS, DIVALENT; CHLORIDES; CHROMATOGRAPHY, ION EXCHANGE; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DENGUE VIRUS; MAGNESIUM CHLORIDE; MANGANESE COMPOUNDS; PROTEIN STRUCTURE, TERTIARY; RNA REPLICASE; VIRAL PROTEINS;

DENGUE VIRUS; FLAVIVIRIDAE;

EID: 33847102726     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309106055084     Document Type: Article

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