Protective efficacy of orally administered, heat-killed Lactobacillus pentosus b240 against influenza A virus

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Kiso, Maki ^a   Takano, Ryo ^a   Sakabe, Saori ^b   Katsura, Hiroaki ^a   Shinya, Kyoko ^c   Uraki, Ryuta ^a   Watanabe, Shinji ^b   Saito, Hiroshi ^d   Toba, Masamichi ^d   Kohda, Noriyuki ^d   Kawaoka, Yoshihiro ^a,b,e  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KOBE UNIVERSITY   (Japan)

^d OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CHEMOKINE; CYTOKINE; EARLY GROWTH RESPONSE FACTOR 1; EGR1 PROTEIN, MOUSE; PROBIOTIC AGENT;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL LINE; DOG; DRUG EFFECT; FEMALE; IMMUNOLOGY; INFLUENZA VIRUS A H1N1; INNATE IMMUNITY; LACTOBACILLUS; LUNG; MDCK CELL; METABOLISM; MOUSE; ORAL DRUG ADMINISTRATION; ORTHOMYXOVIRUS INFECTION; VIROLOGY;

ADMINISTRATION, ORAL; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CHEMOKINES; CYTOKINES; DOGS; EARLY GROWTH RESPONSE PROTEIN 1; FEMALE; IMMUNITY, INNATE; INFLUENZA A VIRUS, H1N1 SUBTYPE; LACTOBACILLUS; LUNG; MADIN DARBY CANINE KIDNEY CELLS; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS; PROBIOTICS;

EID: 84875794923     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep01563     Document Type: Article

References (54)

1. Perez-Padilla, R. et al. Pneumonia and respiratory failure from swine-origin influenza A(H1N1) in Mexico. N. Engl. J. Med. 361, 680-689 (2009).
2. WHO. Statements 2009. World now at the start of 2009 influenza pandemic. 11 June 2009. Accessed at http://www.who.int/mediacentre/news/statements/2009/ en/.
3. Van der Wouden, J. C., Bueving, H. J. & Poole, P. Preventing influenza: an overview of systematic reviews. Respir. Med. 99, 1341-1349 (2005). (Pubitemid 41487492)
4. Guabareva, L. V., Kaiser, L. & Hayden, F. G. Influenza virus neuraminidase inhibitors. Lancet 355, 827-835 (2000). (Pubitemid 30128828)
5. Maeda, N. & Uede, T. Swine-origin influenza-virus-induced acute lung injury: Novel or classical pathogenesis? World J. Biol. Chem. 1, 85-94 (2010).
6. Reid, G. et al. Microbiota restoration: natural and supplemented recovery of human microbial communities. Nat. Rev. Microbiol. 9, 27-38 (2011).
7. Hori, T., Kiyoshima, J., Shida, K. & Yasui, H. Effect of intranasal administration of Lactobacillus casei Shirota on influenza virus infection of upper respiratory tract in mice. Clin. Diagn. Lab. Immunol. 8, 593-597 (2001). (Pubitemid 32428887)
8. Kawase, M.,He, F., Kubota,A., Harata, G.&Hiramatsu, M. Oral administration of lactobacilli from human intestinal tract protects mice against influenza virus infection. Lett. Appl. Microbiol. 51, 6-10 (2010).
9. Youn, H. N. et al. Intranasal administration of live Lactobacillus species facilitates protection against influenza virus infection in mice. Antiviral Res. 93, 138-143 (2012).
10. Okada, S., Daengsubha,W., Uchimura, T., Ohara, N. & Kozaki, M. Flora of lactic acid bacteria in Miang produced in northern Thailand. J. Gen. Appl. Microbiol. 32, 57-65 (1986).
11. Yamahira, S., Toba, M., Kishi, K.&Okamatsu,H. Stimulation of mucosal immune system by lactic acid bacteria originating in tea. Jpn. J. Lactic Acid Bact. 17, 57-60 (2006).
12. Kotani, Y. et al. Oral intake of Lactobacillus pentosus strain b240 accelerates salivary immunoglobulin A secretion in the elderly: A radomized, placebocontrolled, double-blind trial. Immun. Aging 7, 11 (2010).
13. Tanaka, A. et al. Lactobacillus pentosus strain b240 suppresses pneumonia induced by Streptococcus pneumoniae in mice. Lett. Appl. Microbiol. 53, 35-43 (2011).
14. Kobayashi, N. et al. Oral administration of heat-killed Lactobacillus pentosus strain b240 augments protection against influenza virus infection in mice. Int. Immunopharmacol. 11, 199-203 (2011).
15. Strieter, R. M., Belperio, J. A. & Keane, M. P. Cytokines in innate host defense in the lung. J. Clin. Invest. 109, 699-705 (2002). (Pubitemid 34263143)
16. Smith, J. A. Neutrophils, host defense, and inflammation: a double-edged sword. J. Leukoc. Biol. 56, 672-686 (1994).
17. Goodman, R. B., Pugin, J., Lee, L. S. & Matthay, M. A. Cytokine-mediated inflammation in acute lung injury. Cytokine Growth Factor Rev. 14, 523-535 (2003). (Pubitemid 37296025)
18. Bradel-Trethway, B. G. et al. Comprehensive proteomic analysis of influenza virus polymerase complex reveals a novel association with mitochondrial proteins and RNA polymerase accessory factors. J. Virol. 85, 8569-81 (2011).
19. Belisle, S. E. et al. Genomic profiling of tumor necrosis factor alpha (TNF-alpha) receptor and interleukin-1 receptor knockout mice reveals a link between TNFalpha signaling and increased severity of 1918 pandemic influenza virus infection. J. Virol. 84, 12576-12588 (2010).
20. Wang, X., Hinson, E. R. & Cresswell, P. The interferon-inducible protein viperin inhibits influenza virus release by perturbing lipid rafts. Cell Host Microbe 2, 96-105 (2007). (Pubitemid 47209520)
21. Hardwick, J. P. Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases. Biochm. Pharma. 75, 2263-2275 (2008).
22. Kirkby, B., Roman, N., Kobe, B., Kellie, S. & Forwood, J. K. Functional and structural properties of mammalian acyl-coenzyme A thioesterases. Prog. Lipid Res. 49, 366-377 (2010).
23. Di Nunzio, M., Danesi, F. & Bordoni, A. n-3 PUFA as regulators of cardiac gene transcription: a new link between PPAR activation and fatty acid composition. Lipids 44, 1073-1079 (2009).
24. Martin, G., Schoonjans, K., Lefebvre, A. M., Staels, B. & Auwerx, J. Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators. J. Biol. Chem. 272, 28210-28217 (1997). (Pubitemid 27517759)
25. Jiang, Y. J. et al.Modulation of cytosolic phospholipase A(2) by PPAR activators in human preadipocytes. J. Lipid Res. 42, 716-724 (2001). (Pubitemid 32507171)
26. Rouzer, C. A. et al. Lipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications. Biochemistry 45, 14795-14808 (2006). (Pubitemid 44906996)
27. Wallace, M. J. et al. Early biomarkers and potential mediators of ventilationinduced lung injury in very preterm lambs. Respir. Res. 10, 19 (2009).
28. Matute-Bello, G. et al. Essential role of MMP-12 in Fas-induced lung fibrosis. Am. J. Respir. Cell. Mol. Biol. 37, 210-221 (2007). (Pubitemid 47255004)
29. Lin, J. et al. Cyr61 induces IL-6 production by fibroblast-like synoviocytes promoting Th17 differentiation in rheumatoid arthritis. J. Immunol. 188, 5776-5784 (2012).
30. Tatebe, K. et al. Response network analysis of differential gene expression in human epithelial lung cells during avian influenza infections. BMC Bioinformatics. 11, 170 (2010).
31. Ramana, C. V., Cheng, G. S., Kumar, A., Kwon, H. J. & Enelow, R. I. Role of alveolar epithelial early growth response-1 (Egr-1) in CD81 cell-mediated lung injury. Mol. Immunol. 47, 623-631 (2009).
32. Bode, W. & Huber, R. Structural basis of endoproteinase-protein inhibitor interaction. Biochim. Biophys. Acta. 1477, 241-252 (2000). (Pubitemid 30119904)
33. Menzel, K. et al. Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo. Clin. Exp. Immunol. 146, 169-180 (2006). (Pubitemid 44393851)
34. Kim, C. C. et al. Experimental malaria infection triggers early expansion of natural killer cells. Infect. Immun. 76, 5873-5882 (2008).
35. Shaveta, G., Shi, J., Chow, V. T. & Song, J. Structural characterization reveals that viperin is a radical S-adenosyl-L-methionine (SAM) enzyme. Biochem. Biophys. Res. Commun. 391, 1390-1395 (2010).
36. Fitzgerald, K. A. The interferon inducible gene: Viperin. J. Interferon Cytokine Res. 31, 131-135 (2011).
37. Chin, K. C. & Cresswell, P. Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus. Proc. Natl. Acad. Sci. U. S. A. 98, 15125-15130 (2001). (Pubitemid 34013980)
38. Feld, J. J. et al. S-adenosyl methionine improves early viral responses and interferon-stimulated gene induction in hepatitis C nonresponders. Gastroenterology 140, 830-839 (2011).
39. Seo, J. Y., Yaneva, R., Hinson, E. R. & Cresswell, P. Human cytomegalovirus directly induces the antiviral protein Viperin to enhance infectivity. Science 332, 1093-1097 (2011).
40. Jiang, D. et al. Identification of five interferon-induced cellular proteins that inhibit West Nile virus and dengue virus infections. J. Virol. 84, 8332-8341 (2010).
41. Chan, Y. L., Chang, T. H., Liao, C. L. & Lin, Y. L. The cellular antiviral protein Viperin is attenuated by proteasome-mediated protein degradation in Japanese encephalitis virus-infected cells. J. Virol. 82, 10455-10464 (2008).
42. Hinson, E. R. et al. Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection. J. Immunol. 184, 5723-5731 (2010).
43. Saitoh, T. et al. Antiviral protein Viperin promotes Toll-like receptor 7-and Tolllike receptor 9-mediated type I interferon production in plasmacytoid dendritic cells. Immunity 34, 352-363 (2011).
44. Hinson, E. R. & Cresswell, P. The N-terminal amphipathic alpha-helix of Viperin mediates localization to the cytosolic face of the endoplasmic reticulum and inhibits protein secretion. J. Biol. Chem. 284, 4705-4712 (2009).
45. Rivieccio, M. A. et al. TLR3 ligation activates an antiviral response in human fetal astrocytes: a role for Viperin/cig5. J. Immunol. 177, 4735-4741 (2006). (Pubitemid 44469807)
46. Zuercher, A. W., Jiang, H. Q., Thurnheer,M. C., Cuff, C. F. & Cebra, J. J. Distinct mechanisms for cross-protection of the upper versus lower respiratory tract through intestinal priming. J. Immunol. 169, 3920-3925 (2002).
47. Kau, A. L., Ahern, P. P., Griffin, N. W., Goodman, A. L. & Gordon, J. I. Human nutrition, the gut microbiome and the immune system. Nature 474, 327-36 (2011).
48. Charrel-Dennis, M. et al. TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA. Cell Host Microbe. 4, 543-554 (2008). (Pubitemid 352762959)
49. Izumo, T. et al. Comparison of the immunomodulatory effects of live and heatkilled Lactobacillus pentosus S-PT84. J. Heath Sci. 57, 304-310 (2011).
50. Chuang, L. et al.Heat-killed cells of lactobacilli skew the immune response toward T helper 1 polarization in mouse splenocytes and dendritic cell-treated T cells. J. Agric. Food Chem. 55, 11080-11086 (2007).
51. Ishikawa, H. et al. Oral administration of heat-killed Lactobacillus plantarum strain b240 protected mice against Salmonella enterica Serovar Typhimurium. Biosci. Biotechnol. Biochem. 74, 1338-1342 (2010).
52. Sakabe, S., Ozawa, M., Takano, R., Iwatsuki-Horimoto, K. & Kawaoka, Y. Mutations in PA, NP, and HA of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice. Virus Res. 158, 124-129 (2011).
53. Kiso, M. et al. T-705 (favipiravir) activity against lethal H5N1 influenza A viruses. Proc. Natl. Acad. Sci. U. S. A. 107, 882-887 (2010).
54. Livak, K. J. & Schmittgen, T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402-408 (2001). (Pubitemid 34164012)