-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, and Forman D (2011). Global cancer statistics. CA Cancer J Clin 61(2), 69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, Issue.2
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
48249125791
-
Malignant gliomas in adults
-
Wen PY and Kesari S (2008). Malignant gliomas in adults. N Engl J Med 359, 492-507.
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
3
-
-
77951599543
-
Targeting brain cancer: Advances in the molecular pathology of malignant glioma and medulloblastoma
-
Huse JT and Holland EC (2010). Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat Rev Cancer 10, 319-331.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 319-331
-
-
Huse, J.T.1
Holland, E.C.2
-
4
-
-
78651362626
-
Therapeutic options for recurrent malignant glioma
-
Niyazi M, Siefert A, Schwarz SB, Ganswindt U, Kreth FW, Tonn JC, and Belka C (2011). Therapeutic options for recurrent malignant glioma. Radiother Oncol 98, 1-14.
-
(2011)
Radiother Oncol
, vol.98
, pp. 1-14
-
-
Niyazi, M.1
Siefert, A.2
Schwarz, S.B.3
Ganswindt, U.4
Kreth, F.W.5
Tonn, J.C.6
Belka, C.7
-
5
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, et al. (2009). Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10, 459-466.
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
van den Bent, M.J.4
Taphoorn, M.J.5
Janzer, R.C.6
Ludwin, S.K.7
Allgeier, A.8
Fisher, B.9
Belanger, K.10
-
6
-
-
29644442764
-
Receptor tyrosine kinase signaling in gliomagenesis: Pathobiology and therapeutic approaches
-
Kapoor GS and O'Rourke DM (2003). Receptor tyrosine kinase signaling in gliomagenesis: pathobiology and therapeutic approaches. Cancer Biol Ther 2, 330-342.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 330-342
-
-
Kapoor, G.S.1
O'Rourke, D.M.2
-
7
-
-
34547858153
-
Molecular alterations of KIT oncogene in gliomas
-
Gomes AL, Reis-Filho JS, Lopes JM, Martinho O, Lambros MB, Martins A, Schmitt F, Pardal F, and Reis RM (2007). Molecular alterations of KIT oncogene in gliomas. Cell Oncol 29, 399-408.
-
(2007)
Cell Oncol
, vol.29
, pp. 399-408
-
-
Gomes, A.L.1
Reis-Filho, J.S.2
Lopes, J.M.3
Martinho, O.4
Lambros, M.B.5
Martins, A.6
Schmitt, F.7
Pardal, F.8
Reis, R.M.9
-
8
-
-
70249091030
-
Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas
-
Martinho O, Longatto-Filho A, Lambros MB, Martins A, Pinheiro C, Silva A, Pardal F, Amorim J, Mackay A, Milanezi F, et al. (2009). Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas. Br J Cancer 101, 973-982.
-
(2009)
Br J Cancer
, vol.101
, pp. 973-982
-
-
Martinho, O.1
Longatto-Filho, A.2
Lambros, M.B.3
Martins, A.4
Pinheiro, C.5
Silva, A.6
Pardal, F.7
Amorim, J.8
Mackay, A.9
Milanezi, F.10
-
9
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network (2008). Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455, 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
10
-
-
83455176258
-
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
-
Snuderl M, Fazlollahi L, Le LP, Nitta M, Zhelyazkova BH, Davidson CJ, Akhavanfard S, Cahill DP, Aldape KD, Betensky RA, et al. (2011). Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell 20(6), 810-817.
-
(2011)
Cancer Cell
, vol.20
, Issue.6
, pp. 810-817
-
-
Snuderl, M.1
Fazlollahi, L.2
le, L.P.3
Nitta, M.4
Zhelyazkova, B.H.5
Davidson, C.J.6
Akhavanfard, S.7
Cahill, D.P.8
Aldape, K.D.9
Betensky, R.A.10
-
11
-
-
84859376167
-
Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity
-
Little SE, Popov S, Jury A, Bax DA, Doey L, Al-Sarraj S, Jurgensmeier JM, and Jones C (2012). Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity. Cancer Res 72, 1614-1620.
-
(2012)
Cancer Res
, vol.72
, pp. 1614-1620
-
-
Little, S.E.1
Popov, S.2
Jury, A.3
Bax, D.A.4
Doey, L.5
Al-Sarraj, S.6
Jurgensmeier, J.M.7
Jones, C.8
-
12
-
-
84857397985
-
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
-
Szerlip NJ, Pedraza A, Chakravarty D, Azim M, McGuire J, Fang Y, Ozawa T, Holland EC, Huse JT, Jhanwar S, et al. (2012). Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response. Proc Natl Acad Sci USA 109, 3041-3046.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 3041-3046
-
-
Szerlip, N.J.1
Pedraza, A.2
Chakravarty, D.3
Azim, M.4
McGuire, J.5
Fang, Y.6
Ozawa, T.7
Holland, E.C.8
Huse, J.T.9
Jhanwar, S.10
-
13
-
-
33747749871
-
Angiogenesis in malignant glioma-a target for antitumor therapy?
-
Tuettenberg J, Friedel C, and Vajkoczy P (2006). Angiogenesis in malignant glioma-a target for antitumor therapy? Crit Rev Oncol Hematol 59, 181-193.
-
(2006)
Crit Rev Oncol Hematol
, vol.59
, pp. 181-193
-
-
Tuettenberg, J.1
Friedel, C.2
Vajkoczy, P.3
-
14
-
-
55849130720
-
Novel anti-angiogenic therapies for malignant gliomas
-
Norden AD, Drappatz J, and Wen PY (2008). Novel anti-angiogenic therapies for malignant gliomas. Lancet Neurol 7, 1152-1160.
-
(2008)
Lancet Neurol
, vol.7
, pp. 1152-1160
-
-
Norden, A.D.1
Drappatz, J.2
Wen, P.Y.3
-
15
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H, Resta DJ, Reese SF, Ford JM, Capdeville R, and Talpaz M (2001). Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 344, 1038-1042.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.J.4
Reese, S.F.5
Ford, J.M.6
Capdeville, R.7
Talpaz, M.8
-
16
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
Demetri GD, von Mehren M, Blanke CD, Van den Abbeele AD, Eisenberg B, Roberts PJ, Heinrich MC, Tuveson DA, Singer S, Janicek M, et al. (2002). Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 347, 472-480.
-
(2002)
N Engl J Med
, vol.347
, pp. 472-480
-
-
Demetri, G.D.1
von Mehren, M.2
Blanke, C.D.3
van den Abbeele, A.D.4
Eisenberg, B.5
Roberts, P.J.6
Heinrich, M.C.7
Tuveson, D.A.8
Singer, S.9
Janicek, M.10
-
17
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, Oudard S, Negrier S, Szczylik C, Kim ST, et al. (2007). Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 356, 115-124.
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
-
18
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, de Oliveira AC, Santoro A, Raoul JL, Forner A, et al. (2008). Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359, 378-390.
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
de Oliveira, A.C.7
Santoro, A.8
Raoul, J.L.9
Forner, A.10
-
19
-
-
68749098341
-
A Canadian paediatric brain tumour consortium (CPBTC) phase II molecularly targeted study of imatinib in recurrent and refractory paediatric central nervous system tumours
-
Baruchel S, Sharp JR, Bartels U, Hukin J, Odame I, Portwine C, Strother D, Fryer C, Halton J, Egorin MJ, et al. (2009). A Canadian paediatric brain tumour consortium (CPBTC) phase II molecularly targeted study of imatinib in recurrent and refractory paediatric central nervous system tumours. Eur J Cancer 45, 2352-2359.
-
(2009)
Eur J Cancer
, vol.45
, pp. 2352-2359
-
-
Baruchel, S.1
Sharp, J.R.2
Bartels, U.3
Hukin, J.4
Odame, I.5
Portwine, C.6
Strother, D.7
Fryer, C.8
Halton, J.9
Egorin, M.J.10
-
20
-
-
33748376520
-
Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08
-
Wen PY, Yung WKA, Lamborn KR, Dahia PL, Wang YF, Peng B, Abrey LE, Raizer J, Cloughesy TF, Fink K, et al. (2006). Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08. Clin Cancer Res 12, 4899-4907.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4899-4907
-
-
Wen, P.Y.1
Yung, W.K.A.2
Lamborn, K.R.3
Dahia, P.L.4
Wang, Y.F.5
Peng, B.6
Abrey, L.E.7
Raizer, J.8
Cloughesy, T.F.9
Fink, K.10
-
21
-
-
59949083263
-
Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
-
Kreisl TN, Kim L, Moore K, Duic P, Royce C, Stroud I, Garren N, Mackey M, Butman JA, Camphausen K, et al. (2009). Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J Clin Oncol 27, 740-745.
-
(2009)
J Clin Oncol
, vol.27
, pp. 740-745
-
-
Kreisl, T.N.1
Kim, L.2
Moore, K.3
Duic, P.4
Royce, C.5
Stroud, I.6
Garren, N.7
Mackey, M.8
Butman, J.A.9
Camphausen, K.10
-
22
-
-
79953876016
-
Bevacizumab for recurrent glioblastoma multiforme: A meta-analysis
-
Wong ET, Gautam S, Malchow C, Lun M, Pan E, and Brem S (2011). Bevacizumab for recurrent glioblastoma multiforme: a meta-analysis. J Natl Compr Canc Netw 9, 403-407.
-
(2011)
J Natl Compr Canc Netw
, vol.9
, pp. 403-407
-
-
Wong, E.T.1
Gautam, S.2
Malchow, C.3
Lun, M.4
Pan, E.5
Brem, S.6
-
23
-
-
79952740612
-
Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
-
Keunen O, Johansson M, Oudin A, Sanzey M, Rahim SA, Fack F, Thorsen F, Taxt T, Bartos M, Jirik R, et al. (2011). Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc Natl Acad Sci USA 108, 3749-3754.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3749-3754
-
-
Keunen, O.1
Johansson, M.2
Oudin, A.3
Sanzey, M.4
Rahim, S.A.5
Fack, F.6
Thorsen, F.7
Taxt, T.8
Bartos, M.9
Jirik, R.10
-
24
-
-
77952294428
-
Small molecule kinase inhibitors in glioblastoma: A systematic review of clinical studies
-
De Witt Hamer PC (2010). Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies. Neuro Oncol 12, 304-316.
-
(2010)
Neuro Oncol
, vol.12
, pp. 304-316
-
-
de Witt Hamer, P.C.1
-
25
-
-
70450197345
-
Sunitinib: A multitargeted receptor tyrosine kinase inhibitor in the era of molecular cancer therapies
-
Papaetis GS and Syrigos KN (2009). Sunitinib: a multitargeted receptor tyrosine kinase inhibitor in the era of molecular cancer therapies. BioDrugs 23, 377-389.
-
(2009)
BioDrugs
, vol.23
, pp. 377-389
-
-
Papaetis, G.S.1
Syrigos, K.N.2
-
26
-
-
79952541441
-
Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models
-
Navis AC, Hamans BC, Claes A, Heerschap A, Jeuken JW, Wesseling P, and Leenders WP (2011). Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models. J Pathol 223, 626-634.
-
(2011)
J Pathol
, vol.223
, pp. 626-634
-
-
Navis, A.C.1
Hamans, B.C.2
Claes, A.3
Heerschap, A.4
Jeuken, J.W.5
Wesseling, P.6
Leenders, W.P.7
-
27
-
-
78149478057
-
MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib
-
Chahal M, Xu Y, Lesniak D, Graham K, Famulski K, Christensen JG, Aghi M, Jacques A, Murray D, Sabri S, et al. (2010). MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib. Neuro Oncol 12, 822-833.
-
(2010)
Neuro Oncol
, vol.12
, pp. 822-833
-
-
Chahal, M.1
Xu, Y.2
Lesniak, D.3
Graham, K.4
Famulski, K.5
Christensen, J.G.6
Aghi, M.7
Jacques, A.8
Murray, D.9
Sabri, S.10
-
28
-
-
38449097166
-
Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma
-
de Boüard S, Herlin P, Christensen JG, Lemoisson E, Gauduchon P, Raymond E, and Guillamo JS (2007). Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma. Neuro Oncol 9, 412-423.
-
(2007)
Neuro Oncol
, vol.9
, pp. 412-423
-
-
de Boüard, S.1
Herlin, P.2
Christensen, J.G.3
Lemoisson, E.4
Gauduchon, P.5
Raymond, E.6
Guillamo, J.S.7
-
29
-
-
40949141801
-
Impact of angiogenesis inhibition by sunitinib on tumor distribution of temozolomide
-
Zhou Q, Guo P, and Gallo JM (2008). Impact of angiogenesis inhibition by sunitinib on tumor distribution of temozolomide. Clin Cancer Res 14, 1540-1549.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1540-1549
-
-
Zhou, Q.1
Guo, P.2
Gallo, J.M.3
-
30
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/ pharmacodynamic relationship
-
MendelDB, Laird AD, Xin X, Louie SG, Christensen JG, Li G, Schreck RE, Abrams TJ, Ngai TJ, Lee LB, et al. (2003). In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/ pharmacodynamic relationship. Clin Cancer Res 9, 327-337.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
-
31
-
-
0041672482
-
SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
-
Schueneman AJ, Himmelfarb E, Geng L, Tan J, Donnelly E, Mendel D, McMahon G, and Hallahan DE (2003). SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res 63, 4009-4016.
-
(2003)
Cancer Res
, vol.63
, pp. 4009-4016
-
-
Schueneman, A.J.1
Himmelfarb, E.2
Geng, L.3
Tan, J.4
Donnelly, E.5
Mendel, D.6
McMahon, G.7
Hallahan, D.E.8
-
32
-
-
79959795987
-
Phase II study of sunitinib malate in patientswith recurrent high-grade glioma
-
Neyns B, Sadones J, Chaskis C, Dujardin M, Everaert H, Lv S, Duerinck J, Tynninen O, Nupponen N, Michotte A, et al. (2010). Phase II study of sunitinib malate in patientswith recurrent high-grade glioma. J Neurooncol 103(3), 491-501.
-
(2010)
J Neurooncol
, vol.103
, Issue.3
, pp. 491-501
-
-
Neyns, B.1
Sadones, J.2
Chaskis, C.3
Dujardin, M.4
Everaert, H.5
Lv, S.6
Duerinck, J.7
Tynninen, O.8
Nupponen, N.9
Michotte, A.10
-
33
-
-
20144370978
-
AZD2171: A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer
-
Wedge SR, Kendrew J, Hennequin LF, Valentine PJ, Barry ST, Brave SR, Smith NR, James NH, Dukes M, Curwen JO, et al. (2005). AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res 65, 4389-4400.
-
(2005)
Cancer Res
, vol.65
, pp. 4389-4400
-
-
Wedge, S.R.1
Kendrew, J.2
Hennequin, L.F.3
Valentine, P.J.4
Barry, S.T.5
Brave, S.R.6
Smith, N.R.7
James, N.H.8
Dukes, M.9
Curwen, J.O.10
-
34
-
-
79956012866
-
Assessing the activity of cediranib, a VEGFR-2/3 tyrosine kinase inhibitor, against VEGFR-1 and members of the structurally related PDGFR family
-
Brave SR, Ratcliffe K, Wilson Z, James NH, Ashton S, Wainwright A, Kendrew J, Dudley P, Broadbent N, Sproat G, et al. (2011). Assessing the activity of cediranib, a VEGFR-2/3 tyrosine kinase inhibitor, against VEGFR-1 and members of the structurally related PDGFR family. Mol Cancer Ther 10, 861-873.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 861-873
-
-
Brave, S.R.1
Ratcliffe, K.2
Wilson, Z.3
James, N.H.4
Ashton, S.5
Wainwright, A.6
Kendrew, J.7
Dudley, P.8
Broadbent, N.9
Sproat, G.10
-
35
-
-
77954720781
-
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma
-
Batchelor TT, Duda DG, di Tomaso E, Ancukiewicz M, Plotkin SR, Gerstner E, Eichler AF, Drappatz J, Hochberg FH, Benner T, et al. (2010). Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. J Clin Oncol 28, 2817-2823.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2817-2823
-
-
Batchelor, T.T.1
Duda, D.G.2
di Tomaso, E.3
Ancukiewicz, M.4
Plotkin, S.R.5
Gerstner, E.6
Eichler, A.F.7
Drappatz, J.8
Hochberg, F.H.9
Benner, T.10
-
36
-
-
48249092888
-
Normalization of tumor vasculature and alleviation of edema by AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor in glioblastoma patients
-
Batchelor TT, Duda DG, Di Tomaso E, Kozak KR, Zhang W, Ancukiewicz M, Loeffler JS, Wen PY, Sorensen GA, and Jain RK (2007). Normalization of tumor vasculature and alleviation of edema by AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor in glioblastoma patients. Int J Radiat Oncol Biol Phys 69, S50-S51.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.69
-
-
Batchelor, T.T.1
Duda, D.G.2
Di Tomaso, E.3
Kozak, K.R.4
Zhang, W.5
Ancukiewicz, M.6
Loeffler, J.S.7
Wen, P.Y.8
Sorensen, G.A.9
Jain, R.K.10
-
37
-
-
33846149645
-
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
-
Batchelor TT, Sorensen AG, di Tomaso E, Zhang WT, Duda DG, Cohen KS, Kozak KR, Cahill DP, Chen PJ, Zhu M, et al. (2007). AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 11, 83-95.
-
(2007)
Cancer Cell
, vol.11
, pp. 83-95
-
-
Batchelor, T.T.1
Sorensen, A.G.2
di Tomaso, E.3
Zhang, W.T.4
Duda, D.G.5
Cohen, K.S.6
Kozak, K.R.7
Cahill, D.P.8
Chen, P.J.9
Zhu, M.10
-
38
-
-
66349121063
-
Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice
-
Kamoun WS, Ley CD, Farrar CT, Duyverman AM, Lahdenranta J, Lacorre DA, Batchelor TT, di Tomaso E, Duda DG, Munn LL, et al. (2009). Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. J Clin Oncol 27, 2542-2552.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2542-2552
-
-
Kamoun, W.S.1
Ley, C.D.2
Farrar, C.T.3
Duyverman, A.M.4
Lahdenranta, J.5
Lacorre, D.A.6
Batchelor, T.T.7
di Tomaso, E.8
Duda, D.G.9
Munn, L.L.10
-
39
-
-
84856088642
-
Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas
-
Martinho O, Granja S, Jaraquemada T, Caeiro C, Miranda-Goncalves V, Honavar M, Costa P, Damasceno M, Rosner MR, Lopes JM, et al. (2012). Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas. PLoS One 7, e30769.
-
(2012)
PLoS One
, vol.7
-
-
Martinho, O.1
Granja, S.2
Jaraquemada, T.3
Caeiro, C.4
Miranda-Goncalves, V.5
Honavar, M.6
Costa, P.7
Damasceno, M.8
Rosner, M.R.9
Lopes, J.M.10
-
40
-
-
84861820964
-
Angiogenic potential of Gellan-gum-based hydrogels for application in nucleus pulposus regeneration: In vivo study
-
Silva-Correia J, Miranda-Goncalves V, Salgado AJ, Sousa N, Oliveira JM, Reis RM, and Reis RL (2012). Angiogenic potential of Gellan-gum-based hydrogels for application in nucleus pulposus regeneration: in vivo study. Tissue Eng Part A 18(11-12), 1203-1212.
-
(2012)
Tissue Eng Part A
, vol.18
, Issue.11-12
, pp. 1203-1212
-
-
Silva-Correia, J.1
Miranda-Goncalves, V.2
Salgado, A.J.3
Sousa, N.4
Oliveira, J.M.5
Reis, R.M.6
Reis, R.L.7
-
41
-
-
84871200220
-
Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness
-
Moniz S, Martinho O, Pinto F, Sousa B, Loureiro C, Oliveira MJ, Moita LF, Honavar M, Pinheiro C, Pires M, et al. (2013). Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness. Hum Mol Genet 22(1), 84-95.
-
(2013)
Hum Mol Genet
, vol.22
, Issue.1
, pp. 84-95
-
-
Moniz, S.1
Martinho, O.2
Pinto, F.3
Sousa, B.4
Loureiro, C.5
Oliveira, M.J.6
Moita, L.F.7
Honavar, M.8
Pinheiro, C.9
Pires, M.10
-
42
-
-
33746919951
-
Characterization of an imatinib-sensitive subset of high-grade human glioma cultures
-
Hagerstrand D, Hesselager G, Achterberg S, Wickenberg BU, Kowanetz M, Kastemar M, Heldin CH, Isaksson A, Nister M, and Ostman A (2006). Characterization of an imatinib-sensitive subset of high-grade human glioma cultures. Oncogene 25, 4913-4922.
-
(2006)
Oncogene
, vol.25
, pp. 4913-4922
-
-
Hagerstrand, D.1
Hesselager, G.2
Achterberg, S.3
Wickenberg, B.U.4
Kowanetz, M.5
Kastemar, M.6
Heldin, C.H.7
Isaksson, A.8
Nister, M.9
Ostman, A.10
-
43
-
-
58749088233
-
Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells
-
Shingu T, Fujiwara K, Bogler O, Akiyama Y, Moritake K, Shinojima N, Tamada Y, Yokoyama T, and Kondo S (2009). Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells. Int J Cancer 124, 1060-1071.
-
(2009)
Int J Cancer
, vol.124
, pp. 1060-1071
-
-
Shingu, T.1
Fujiwara, K.2
Bogler, O.3
Akiyama, Y.4
Moritake, K.5
Shinojima, N.6
Tamada, Y.7
Yokoyama, T.8
Kondo, S.9
-
44
-
-
75049085335
-
In-vitro effects of the tyrosine kinase inhibitor imatinib on glioblastoma cell proliferation
-
Ranza E, Mazzini G, Facoetti A, and Nano R (2010). In-vitro effects of the tyrosine kinase inhibitor imatinib on glioblastoma cell proliferation. J Neurooncol 96, 349-357.
-
(2010)
J Neurooncol
, vol.96
, pp. 349-357
-
-
Ranza, E.1
Mazzini, G.2
Facoetti, A.3
Nano, R.4
-
45
-
-
33746089134
-
Platelet-derived growth factor receptor independent proliferation of human glioblastoma cells: Selective tyrosine kinase inhibitors lack antiproliferative activity
-
Gross D, Bernhardt G, and Buschauer A (2006). Platelet-derived growth factor receptor independent proliferation of human glioblastoma cells: selective tyrosine kinase inhibitors lack antiproliferative activity. J Cancer Res Clin Oncol 132, 589-599.
-
(2006)
J Cancer Res Clin Oncol
, vol.132
, pp. 589-599
-
-
Gross, D.1
Bernhardt, G.2
Buschauer, A.3
-
46
-
-
78751485498
-
The effects of anti-VEGFR and anti-EGFR agents on glioma cell migration through implication of growth factors with integrins
-
Dimitropoulos K, Giannopoulou E, Argyriou AA, Zolota V, Petsas T, Tsiata E, and Kalofonos HP (2010). The effects of anti-VEGFR and anti-EGFR agents on glioma cell migration through implication of growth factors with integrins. Anticancer Res 30, 4987-4992.
-
(2010)
Anticancer Res
, vol.30
, pp. 4987-4992
-
-
Dimitropoulos, K.1
Giannopoulou, E.2
Argyriou, A.A.3
Zolota, V.4
Petsas, T.5
Tsiata, E.6
Kalofonos, H.P.7
-
47
-
-
77956047415
-
An in vitro study, evaluating the effect of sunitinib and/or lapatinib on two glioma cell lines
-
Giannopoulou E, Dimitropoulos K, Argyriou AA, Koutras AK, Dimitrakopoulos F, and Kalofonos HP (2010). An in vitro study, evaluating the effect of sunitinib and/or lapatinib on two glioma cell lines. Invest New Drugs 28, 554-560.
-
(2010)
Invest New Drugs
, vol.28
, pp. 554-560
-
-
Giannopoulou, E.1
Dimitropoulos, K.2
Argyriou, A.A.3
Koutras, A.K.4
Dimitrakopoulos, F.5
Kalofonos, H.P.6
-
48
-
-
82955182157
-
Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: Implications for the clinic
-
Wachsberger PR, Lawrence RY, Liu Y, Xia X, Andersen B, and Dicker AP (2011). Cediranib enhances control of wild type EGFR and EGFRvIII-expressing gliomas through potentiating temozolomide, but not through radiosensitization: implications for the clinic. J Neurooncol 105(2), 181-190.
-
(2011)
J Neurooncol
, vol.105
, Issue.2
, pp. 181-190
-
-
Wachsberger, P.R.1
Lawrence, R.Y.2
Liu, Y.3
Xia, X.4
Andersen, B.5
Dicker, A.P.6
-
49
-
-
83955164321
-
Epidermal growth factor receptor expression modulates antitumor efficacy of vandetanib or cediranib combined with radiotherapy in human glioblastoma xenografts
-
Wachsberger PR, Lawrence YR, Liu Y, Daroczi B, Xu X, and Dicker AP (2010). Epidermal growth factor receptor expression modulates antitumor efficacy of vandetanib or cediranib combined with radiotherapy in human glioblastoma xenografts. Int J Radiat Oncol Biol Phys 82(1), 483-491.
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.82
, Issue.1
, pp. 483-491
-
-
Wachsberger, P.R.1
Lawrence, Y.R.2
Liu, Y.3
Daroczi, B.4
Xu, X.5
Dicker, A.P.6
-
50
-
-
78651408563
-
Glioblastoma recurrence after cediranib therapy in patients: Lack of "rebound" revascularization as mode of escape
-
di Tomaso E, Snuderl M, Kamoun WS, Duda DG, Auluck PK, Fazlollahi L, Andronesi OC, Frosch MP, Wen PY, Plotkin SR, et al. (2011). Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. Cancer Res 71, 19-28.
-
(2011)
Cancer Res
, vol.71
, pp. 19-28
-
-
di Tomaso, E.1
Snuderl, M.2
Kamoun, W.S.3
Duda, D.G.4
Auluck, P.K.5
Fazlollahi, L.6
Andronesi, O.C.7
Frosch, M.P.8
Wen, P.Y.9
Plotkin, S.R.10
-
51
-
-
36048994736
-
Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment
-
Hoelzinger DB, Demuth T, and Berens ME (2007). Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment. J Natl Cancer Inst 99, 1583-1593.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1583-1593
-
-
Hoelzinger, D.B.1
Demuth, T.2
Berens, M.E.3
-
52
-
-
60349096583
-
Differential effect of imatinib and synergismof combination treatment with chemotherapeutic agents in malignant glioma cells
-
Ren H, Tan X, Dong Y, Giese A, Chou TC, Rainov N, and Yang B (2009). Differential effect of imatinib and synergismof combination treatment with chemotherapeutic agents in malignant glioma cells. Basic Clin Pharmacol Toxicol 104, 241-252.
-
(2009)
Basic Clin Pharmacol Toxicol
, vol.104
, pp. 241-252
-
-
Ren, H.1
Tan, X.2
Dong, Y.3
Giese, A.4
Chou, T.C.5
Rainov, N.6
Yang, B.7
-
53
-
-
35348822482
-
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
-
Stommel JM, Kimmelman AC, Ying H, Nabioullin R, Ponugoti AH, Wiedemeyer R, Stegh AH, Bradner JE, Ligon KL, Brennan C, et al. (2007). Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science 318, 287-290.
-
(2007)
Science
, vol.318
, pp. 287-290
-
-
Stommel, J.M.1
Kimmelman, A.C.2
Ying, H.3
Nabioullin, R.4
Ponugoti, A.H.5
Wiedemeyer, R.6
Stegh, A.H.7
Bradner, J.E.8
Ligon, K.L.9
Brennan, C.10
-
54
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, Park JO, LindemanN, Gale CM, Zhao X, Christensen J, et al. (2007). MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316, 1039-1043.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
Lindeman, N.7
Gale, C.M.8
Zhao, X.9
Christensen, J.10
-
55
-
-
34249985524
-
A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors
-
Mahadevan D, Cooke L, Riley C, Swart R, Simons B, DellaCK, Wisner L, Iorio M, Shakalya K, Garewal H, et al. (2007). A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors. Oncogene 26, 3909-3919.
-
(2007)
Oncogene
, vol.26
, pp. 3909-3919
-
-
Mahadevan, D.1
Cooke, L.2
Riley, C.3
Swart, R.4
Simons, B.5
Della, C.K.6
Wisner, L.7
Iorio, M.8
Shakalya, K.9
Garewal, H.10
|