메뉴 건너뛰기




Volumn 72, Issue 7, 2012, Pages 1614-1620

Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER GRADING; CELL HETEROGENEITY; CONTROLLED STUDY; EGFR GENE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE FREQUENCY; GENE LOCATION; GENE MAPPING; GENETIC VARIABILITY; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; MALE; ONCOGENE; PDGFRA GENE; PRIORITY JOURNAL; RECEPTOR GENE;

EID: 84859376167     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-4069     Document Type: Article
Times cited : (99)

References (20)
  • 2
    • 75549083303 scopus 로고    scopus 로고
    • Tumor heterogeneity: Causes and consequences
    • Marusyk A, Polyak K. Tumor heterogeneity: causes and consequences. Biochim Biophys Acta 2010;1805:105-17.
    • (2010) Biochim Biophys Acta , vol.1805 , pp. 105-117
    • Marusyk, A.1    Polyak, K.2
  • 3
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC. The clonal evolution of tumor cell populations. Science 1976;194:23-8.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 4
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008;8: 755-68.
    • (2008) Nat Rev Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 9
    • 8744234208 scopus 로고    scopus 로고
    • Immunohistochemical analysis of the mutant epidermal growth factor, deltaEGFR, in glioblastoma
    • DOI 10.1007/BF02484510
    • Nishikawa R, Sugiyama T, Narita Y, Furnari F, Cavenee WK, Matsutani M. Immunohistochemical analysis of the mutant epidermal growth factor, delta EGFR, in glioblastoma. Brain Tumor Pathol 2004;21:53-6. (Pubitemid 39518146)
    • (2004) Brain Tumor Pathology , vol.21 , Issue.2 , pp. 53-56
    • Nishikawa, R.1    Sugiyama, T.2    Narita, Y.3    Furnari, F.4    Cavenee, W.K.5    Matsutani, M.6
  • 10
    • 51649117107 scopus 로고    scopus 로고
    • Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity
    • Hegi ME, Liu L, Herman JG, Stupp R, Wick W, Weller M, et al. Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity. J Clin Oncol 2008;26:4189-99.
    • (2008) J Clin Oncol , vol.26 , pp. 4189-4199
    • Hegi, M.E.1    Liu, L.2    Herman, J.G.3    Stupp, R.4    Wick, W.5    Weller, M.6
  • 12
    • 0032532078 scopus 로고    scopus 로고
    • Intratumoral cytogenetic heterogeneity detected by comparative genomic hybridization and laser scanning cytometry in human gliomas
    • Harada K, Nishizaki T, Ozaki S, Kubota H, Ito H, Sasaki K. Intratumoral cytogenetic heterogeneity detected by comparative genomic hybridization and laser scanning cytometry in human gliomas. Cancer Res 1998;58:4694-700. (Pubitemid 28480637)
    • (1998) Cancer Research , vol.58 , Issue.20 , pp. 4694-4700
    • Harada, K.1    Nishizaki, T.2    Ozaki, S.3    Kubota, H.4    Ito, H.5    Sasaki, K.6
  • 13
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • McLendon R, Friedman A, Bigner D, Van Meir EG, Brat DJ, Mastrogianakis M, et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008;455: 1061-8.
    • (2008) Nature , vol.455 , pp. 1061-1068
    • McLendon, R.1    Friedman, A.2    Bigner, D.3    Van Meir, E.G.4    Brat, D.J.5    Mastrogianakis, M.6
  • 15
    • 70349456789 scopus 로고    scopus 로고
    • EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines
    • Bax DA, Gaspar N, Little SE, Marshall L, Perryman L, Regairaz M, et al. EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines. Clin Cancer Res 2009;15:5753-61.
    • (2009) Clin Cancer Res , vol.15 , pp. 5753-5761
    • Bax, D.A.1    Gaspar, N.2    Little, S.E.3    Marshall, L.4    Perryman, L.5    Regairaz, M.6
  • 16
    • 80054771090 scopus 로고    scopus 로고
    • Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma
    • Paugh BS, Broniscer A, Qu C, Miller CP, Zhang J, Tatevossian RG, et al. Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. J Clin Oncol 2011;29:3999-4006.
    • (2011) J Clin Oncol , vol.29 , pp. 3999-4006
    • Paugh, B.S.1    Broniscer, A.2    Qu, C.3    Miller, C.P.4    Zhang, J.5    Tatevossian, R.G.6
  • 18
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010;17:98-110.
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6
  • 20
    • 78751644099 scopus 로고    scopus 로고
    • Genetic variegation of clonal architecture and propagating cells in leukaemia
    • Anderson K, Lutz C, van Delft FW, Bateman CM, Guo Y, Colman SM, et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 2011;469:356-61.
    • (2011) Nature , vol.469 , pp. 356-361
    • Anderson, K.1    Lutz, C.2    Van Delft, F.W.3    Bateman, C.M.4    Guo, Y.5    Colman, S.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.