Perfluorooctane sulfonate induces neuronal and oligodendrocytic differentiation in neural stem cells and alters the expression of PPARγ in vitro and in vivo

Toxicology and Applied Pharmacology

Volumn 269, Issue 1, 2013, Pages 51-60

  Wan Ibrahim, Wan Norhamidah ^a,b   Tofighi, Roshan ^a   Onishchenko, Natalia ^a   Rebellato, Paola ^a   Bose, Raj ^a   Uhlén, Per ^a   Ceccatelli, Sandra ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Calcium; Differentiation; Neural stem cells; PFOS; PPAR; Proliferation

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; 2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; CALCIUM ION; PERFLUOROOCTANESULFONIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; SUPEROXIDE DISMUTASE; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PRENATAL EXPOSURE; PROTEIN EXPRESSION; PROTEIN TARGETING; UPREGULATION;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; ALKANESULFONIC ACIDS; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BRAIN; CALCIUM; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC STEM CELLS; ENVIRONMENTAL POLLUTANTS; FLUOROCARBONS; GENE EXPRESSION REGULATION; ION CHANNELS; MICE; MICE, INBRED C57BL; MITOCHONDRIAL PROTEINS; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; OLIGODENDROGLIA; PPAR GAMMA; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TUBULIN;

RATTUS;

EID: 84875780562     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.03.003     Document Type: Article

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