Elevated glutathione peroxidase in newly diagnosed hypertension: Its relation to insulin resistance

Clinical and Experimental Hypertension

Volumn 35, Issue 3, 2013, Pages 195-199

  Selvaraj, Nambiar ^a   Sathiyapriya, Viswanathan ^a   Bobby, Zachariah ^a   Nandeesha, Hanumanthappa ^a   Aparna, Agrawal ^a  

^a JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Glutathione peroxidase; Hyperinsulinemia; Hypertension; Insulin resistance; Oxidative stress

Indexed keywords

GLUTATHIONE PEROXIDASE; INSULIN;

ADULT; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; ESSENTIAL HYPERTENSION; FEMALE; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HOMEOSTASIS MODEL ASSESSMENT INSULIN RESISTANCE INDEX; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES;

ADULT; CASE-CONTROL STUDIES; ENZYME ASSAYS; GLUTATHIONE PEROXIDASE; HUMANS; HYPERTENSION; INSULIN; INSULIN RESISTANCE; MIDDLE AGED; OXIDATIVE STRESS;

EID: 84875756138     PISSN: 10641963     EISSN: 15256006     Source Type: Journal    
DOI: 10.3109/10641963.2012.712178     Document Type: Article

References (44)

1. Ferrannini E, Buzzigoli G, Bonadonna R. Insulin resistance in essential hypertension. N Engl J Med 1987; 317:350-357.
2. Sowers JR, Epstein M, Frohlich ED. Diabetes, hypertension, and cardiovascular disease: an update. Hypertension 2001; 37: 1053-1059.
3. Sathiyapriya V, Nandeesha H, Bobby Z, Pavithran P, Selvaraj N, Rattina Dasse N. Insulin resistance and enhanced protein glyca-tion in men with prehypertension. Clin Chem Lab Med 2006; 44:1457-1461.
4. Reaven GM, Lithell H, Landsberg L. Hypertension and associated metabolic abnormalities-the role of insulin resistance and the sympathoadrenal system. N Engl J Med 1996; 334: 374-381.
5. Lind L, Berne C, Lithell H. Prevalence of insulin resistance in essential hypertension. J Hypertens 1995; 13:1457-1462.
6. Tuck ML. Metabolic considerations in hypertension. Am J Hypertens 1990; 3:355S-365S.
7. Dengel DR, Pratley RE, Hagberg JM, Goldberg AP. Impaired insulin sensitivity and maximal responsiveness in older hypertensive men. Hypertension 1994; 23:320-324.
8. Sechi LA, Tedde R, Marigliano A, Melis A, Pala A, Orecchioni C. Insulin resistance and beta-cell hypersecretion in essential hypertension. J Hypertens Suppl 1990; 8:S87-S89.
9. Pollare T, Lithell H, Berne C. Insulin resistance is a characteristic feature of primary hypertension independent of obesity. Metabolism 1990; 39:167-174.
10. Morales PA, Mitchell BD, Valdez RA, Hazuda HP, Stern MP, Haffner SM. Incidence of NIDDM and impaired glucose tolerance in hypertensive subjects: the San Antonio Heart Study. Diabetes 1993; 42:154-161.
11. Gress TW, Nieto FJ, Shahar E, Wofford MR, Brancati FL. Hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus: Atherosclerosis Risk in Communities Study. N Engl J Med 2000; 342:905-912.
12. Salomaa VV, Strandberg TE, Vanhanen H, Naukkarinen V, Sarna S, Miettinen TA. Glucose tolerance and blood pressure: long term follow up in middle aged men. Br Med J 1991; 302: 493-496.
13. Xu L, Badr MZ. Enhanced potential for oxidative stress in hyperinsulinemic rats: imbalance between hepatic peroxisomal hydrogen peroxide production and decomposition due to hyper-insulinemia. Horm Metab Res 1999; 31:278-282.
14. Sathiyapriya V, Selvaraj N, Nandeesha H, Bobby Z, Agrawal A, Pavithran P. Enhanced glycation of hemoglobin and plasma proteins is associated with increased lipid peroxides levels in non-diabetic hypertensive subjects. Arch Med Res 2007; 38: 822-826.
15. Sathiyapriya V, Selvaraj N, Bobby Z, Agrawal A. Perturbation of erythrocyte antioxidant barrier, lipid peroxidation and protein carbonylation in non-diabetic first degree relatives of patients with type 2 diabetes. Diabetes Res Clin Pract 2007; 78:171-175.
16. Parik T, Allikmets K, Teesalu R, Zilmer M. Oxidative stress and hyperinsulinemia in essential hypertension: different factors for increased risk. J Hypertens 1996; 14:407-410.
17. Brownlee M. The pathobiology of diabetic complications. A unifying mechanism. Diabetes 2005; 54:1615-1625.
18. Nambiar S, Viswanathan S, Zachariah B, Hanumanthappa N, Magadi SG. Oxidative stress in prehypertension: rationale for antioxidant clinical trials. Angiology 2009; 60:221-234.
19. Selvaraj N, Bobby Z, Sridhar MG. Increased glycation of hemoglobin in chronic renal failure: potential role of oxidative stress. Arch Med Res 2008; 39:277-284.
20. Stocker R, Keaney Jr, JF. Role of oxidative modifications in atherosclerosis. Physiol Rev 2004; 114:1752-1761.
21. Selvaraj N, Bobby Z, Sridhar MG. Oxidative stress: does it play a role in the genesis of early glycated proteins? Med Hypotheses 2008; 70:265-268.
22. Lei XG, Cheng W-H, McClung JP. Metabolic regulation and function of glutathione peroxidase-1. Annu Rev Nutr 2007; 27:41-61.
23. Chen X, Scholl TO, Leskiw MJ, Donaldson MR, Stein TP. Association of glutathione peroxidase activity with insulin resistance and dietary fat intake during normal pregnancy. J Clin Endocrinol Metab 2003; 88:5963-5968.
24. McClung JP, Roneker CA, Mu W, et al. Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase. Proc Natl Acad Sci USA 2004; 101:8852-8857.
25. Loh K, Deng H, Fukushima A, et al. Reactive oxygen species enhance insulin sensitivity. Cell Metab 2009; 10:260-272.
26. Simic DV, Mimic-Oka J, Plijesa-Ercegovac M, et al. Byproducts of oxidative protein damage and antioxidant enzyme activities in plasma of patients with different degrees of essential hypertension. J Hum Hypertens 2006; 20:149-155.
27. Nandeesha H, Sathiyapriya V, Bobby Z, Pavithran P, Agrawal A, Selvaraj N. Altered oxidant-antioxidant status in non-obese men with moderate essential hypertension. Indian J Med Sci 2007; 61:326-331.
28. Sathiyapriya V, Nandeesha H, Bobby Z, Selvaraj N, Pavithran P. Pertubation of oxidant-antioxidant status in non-obese prehyper-tensive male subjects. J Hum Hypertens 2007; 21:176-178.
29. Chobanian AV, Bakris GL, Black HR, et al.; the National Heart, Lung and blood Institute Joint National Committee on Prevention Detection, Evaluation and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. Seventh report of the joint national committee on prevention, detection, evaluation and treatment of high blood pressure: the JNC 7 report. J Am Med Assoc 2003; 289:2560-2572.
30. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28:412-419.
31. Wendel A. Glutathione peroxidase. Methods Enzymol 1981; 77:325-333.
32. Beutler E, Duron O, Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med 1963; 61:882-888.
33. Drabkin DL, Austin JN. Spectrophotometric studies. I. Spectrophotometric constants for common hemoglobin derivatives in human, dog and rabbit. J Biol Chem 1932; 98:719-733.
34. Shen DC, Shieh SM, Fuh MT, Wu DA, Chen YD, Reaven GM. Resistance to insulin stimulated glucose uptake in patients with hypertension. J Clin Endocrinol Metab 1988; 66:580-583.
35. Reaven GM, Chang H. Relationship between blood pressure, plasma insulin and triglyceride concentration, and insulin action in spontaneous hypertensive and Wistar-Kyoto rats. Am J Hypertens 1991; 4:34-38.
36. Vasdev S, Gill V, Parai S, Gadag V. Dietary lipoic acid supplementation attenuates hypertension in Dahl salt sensitive rats. Mol Cell Biochem 2005; 275:135-141.
37. Zemel MB, Peuler JD, Sowers JR, Simpson L. Hypertension in insulin-resistant Zucker obese rats is independent of sympathetic neural support. Am J Physiol 1992; 262:E368-E371.
38. Campbell IW, Dominiczak AF, Livingstone C, Gould GW. Analysis of the glucose transporter compliment of metabolically important tissues from the Milan hypertensive rat. Biochem Biophys Res Commun 1995; 211:780-791.
39. Mates JM, Perez-Gomez C, Nunez de Castro I. Antioxidant enzymes and human diseases. Clin Biochem 1999; 32: 595-603.
40. Lu D, Maulik N, Moraru II, Kreutzer DL, Das DK. Molecular adaptation of vascular endothelial cells to oxidative stress. Am J Physiol 1993; 264:C715-C722.
41. Kaaja RJ, Greer IA. Manifestations of chronic disease during pregnancy. J Am Med Assoc 2005; 294:2751-2757.
42. Yang H, Jin X, Lam CW, Yan SK. Oxidative stress and diabetes mellitus. Clin Chem Lab Med 2011; 49:1773-1782.
43. Vinayaga Moorthi R, Bobby Z, Selvaraj N, Sridhar MG. Vitamin E protects the insulin sensitivity and redox balance in rat L6 muscle cells exposed to oxidative stress. Clin Chim Acta 2006; 367:132-136.
44. Vinayagamoorthi R, Bobby Z, Sridhar MG. Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance. J Endocrinol 2008; 197:287-296.