Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin

Journal of Allergy and Clinical Immunology

Volumn 131, Issue 4, 2013, Pages 1094-1102

  Pellerin, Laurence ^a,b,c   Henry, Julie ^a,b,c   Hsu, Chiung Yueh ^a,b,c   Balica, Stéfana ^d   Jean Decoster, Catherine ^e   Méchin, Marie Claire ^a,b,c   Hansmann, Britta ^f   Rodriguez, Elke ^f   Weindinger, Stefan ^f   Schmitt, Anne Marie ^e   Serre, Guy ^a,b,c   Paul, Carle ^a,b,c,d   Simon, Michel ^a,b,c  

^a CHU PURPAN   (France)

^b INSERM   (France)

^c UNIVERSITÉ DE TOULOUSE   (France)

^d TOULOUSE UNIVERSITY HOSPITAL   (France)

^e Centre Européen de Recherche sur la Peau et les Epithéliums de Revêtement   (France)

^f UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Atopic dermatitis; cytokine; filaggrin; hornerin; keratinocytes; skin; skin barrier; stratum corneum

Indexed keywords

CINTREDEKIN BESUDOTOX; FILAGGRIN; FLG2 PROTEIN; HORNERIN; INTERLEUKIN 25; INTERLEUKIN 4; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; DERMATITIS; DISEASE DURATION; DISEASE SEVERITY; DOWN REGULATION; FEMALE; GENOTYPE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNODETECTION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MALE; NONSENSE MUTATION; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN EXPRESSION; SKIN BIOPSY; STRATUM CORNEUM; WILD TYPE;

ADULT; BLOTTING, WESTERN; CALCIUM-BINDING PROTEINS; CASE-CONTROL STUDIES; DERMATITIS, ATOPIC; DOWN-REGULATION; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-13; INTERLEUKIN-17; INTERLEUKIN-4; INTERMEDIATE FILAMENT PROTEINS; KERATINOCYTES; MALE; PRIMARY CELL CULTURE; S100 PROTEINS; SKIN;

EID: 84875745773     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.12.1566     Document Type: Article

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