Dopamine but not l-dopa stimulates neural glutathione metabolism. Potential implications for Parkinson's and other dopamine deficiency states

Neurochemistry International

Volumn 62, Issue 5, 2013, Pages 684-694

  Allen, George F G ^a   Ullah, Yasmin ^b   Hargreaves, Iain P ^a,c   Land, John M ^a,c   Heales, Simon J R ^a,c,d,e,f  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e Chemical Pathology   (United Kingdom)

^f GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

Antioxidant response elements; Aromatic l amino acid decarboxylase deficiency; Dopamine; Glutathione trafficking; l Dopa; Reduced glutathione

Indexed keywords

AROMATIC LEVO AMINO ACID DECARBOXYLASE; DOPAMINE; GLUTATHIONE; LEVODOPA;

ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; CELL MIGRATION; ENZYME ACTIVITY; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; NERVE CELL; NEUROBLASTOMA CELL; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; UPREGULATION;

AROMATIC-L-AMINO-ACID DECARBOXYLASES; BRAIN; CELL LINE, TUMOR; DOPAMINE; GLUTATHIONE; HUMANS; LEVODOPA; NEURONS; PARKINSON DISEASE;

EID: 84875744470     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.12.004     Document Type: Article

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