-
1
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn EH. Structure and function of telomeres. Nature. 1991;350(6319):569-573.
-
(1991)
Nature
, vol.350
, Issue.6319
, pp. 569-573
-
-
Blackburn, E.H.1
-
2
-
-
0029894237
-
Telomere length regulation
-
Greider CW. Telomere length regulation. Annu Rev Biochem. 1996;65:337-365.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 337-365
-
-
Greider, C.W.1
-
3
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay JW, Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer. 1997;33(5):787-791.
-
(1997)
Eur J Cancer
, vol.33
, Issue.5
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
4
-
-
0032009536
-
Telomerase activity in cancer: A magic bullet or a mirage?
-
Soria JC, Vielh P, el-Naggar AK. Telomerase activity in cancer: a magic bullet or a mirage? Adv Anat Pathol. 1998;5(2):86-94.
-
(1998)
Adv Anat Pathol
, vol.5
, Issue.2
, pp. 86-94
-
-
Soria, J.C.1
Vielh, P.2
El-Naggar, A.K.3
-
5
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase iii study: 5-year analysis of the eortc-ncic trial
-
Stupp R, Hegi ME, Mason WP, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009;10(5):459-466.
-
(2009)
Lancet Oncol
, vol.10
, Issue.5
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
-
6
-
-
74049107766
-
Diagnostic and prognostic markers in gliomas
-
Ducray F, El Hallani S, Idbaih A. Diagnostic and prognostic markers in gliomas. Curr Opin Oncol. 2009;21(6):537-542.
-
(2009)
Curr Opin Oncol
, vol.21
, Issue.6
, pp. 537-542
-
-
Ducray, F.1
El Hallani, S.2
Idbaih, A.3
-
7
-
-
20044372154
-
Mgmt gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med. 2005; 352(10):997-1003.
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
8
-
-
75749109750
-
O6-methylguanine dna methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients
-
Spiegl-Kreinecker S, Pirker C, Filipits M, et al. O6-methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients. Neuro Oncol. 2010;12(1):28-36.
-
(2010)
Neuro Oncol
, vol.12
, Issue.1
, pp. 28-36
-
-
Spiegl-Kreinecker, S.1
Pirker, C.2
Filipits, M.3
-
9
-
-
73349103157
-
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: A prospective translational study of the german glioma network
-
Weller M, Felsberg J, Hartmann C, et al. Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol. 2009;27(34):5743-5750.
-
(2009)
J Clin Oncol
, vol.27
, Issue.34
, pp. 5743-5750
-
-
Weller, M.1
Felsberg, J.2
Hartmann, C.3
-
10
-
-
0028827339
-
Telomerase activity in human brain tumours
-
Langford LA, Piatyszek MA, Xu R, Schold SC Jr., Shay JW. Telomerase activity in human brain tumours. Lancet. 1995;346(8985):1267-1268.
-
(1995)
Lancet
, vol.346
, Issue.8985
, pp. 1267-1268
-
-
Langford, L.A.1
Piatyszek, M.A.2
Xu, R.3
Schold Jr., S.C.4
Shay, J.W.5
-
11
-
-
38449092894
-
Relation between telomerase activity, htert and telomere length for intracranial tumours
-
Maes L, Van Neste L, Van Damme K, et al. Relation between telomerase activity, hTERT and telomere length for intracranial tumours. Oncol Rep. 2007;18(6):1571-1576.
-
(2007)
Oncol Rep
, vol.18
, Issue.6
, pp. 1571-1576
-
-
Maes, L.1
Van Neste, L.2
Van Damme, K.3
-
12
-
-
43749101824
-
Differential htert mrna processing between young and older glioma patients
-
Shervington A, Patel R. Differential hTERT mRNA processing between young and older glioma patients. FEBS Lett. 2008;582(12):1707-1710.
-
(2008)
FEBS Lett
, vol.582
, Issue.12
, pp. 1707-1710
-
-
Shervington, A.1
Patel, R.2
-
13
-
-
33846395138
-
Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma
-
Shervington A, Patel R, Lu C, et al. Telomerase subunits expression variation between biopsy samples and cell lines derived from malignant glioma. Brain Res. 2007;1134(1):45-52.
-
(2007)
Brain Res
, vol.1134
, Issue.1
, pp. 45-52
-
-
Shervington, A.1
Patel, R.2
Lu, C.3
-
14
-
-
33747109928
-
Telomerase activity and htert mrna expression in glial tumors
-
Boldrini L, Pistolesi S, Gisfredi S, et al. Telomerase activity and hTERT mRNA expression in glial tumors. Int J Oncol. 2006;28(6):1555-1560.
-
(2006)
Int J Oncol
, vol.28
, Issue.6
, pp. 1555-1560
-
-
Boldrini, L.1
Pistolesi, S.2
Gisfredi, S.3
-
15
-
-
0037426088
-
Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme
-
Hakin-Smith V, Jellinek DA, Levy D, et al. Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme. Lancet. 2003;361(9360):836-838.
-
(2003)
Lancet
, vol.361
, Issue.9360
, pp. 836-838
-
-
Hakin-Smith, V.1
Jellinek, D.A.2
Levy, D.3
-
16
-
-
0033809069
-
Expression of the major vault protein lrp in human non-small-cell lung cancer cells: Activation by short-term exposure to antineoplastic drugs
-
Berger W, Elbling L, Micksche M. Expression of the major vault protein LRP in human non-small-cell lung cancer cells: activation by short-term exposure to antineoplastic drugs. Int J Cancer. 2000;88(2):293-300.
-
(2000)
Int J Cancer
, vol.88
, Issue.2
, pp. 293-300
-
-
Berger, W.1
Elbling, L.2
Micksche, M.3
-
17
-
-
45249110498
-
A quantitative realtime pcr method for absolute telomere length
-
O'Callaghan N, Dhillon V, Thomas P, Fenech M. A quantitative realtime PCR method for absolute telomere length. BioTechniques. 2008;44(6):807-809.
-
(2008)
BioTechniques
, vol.44
, Issue.6
, pp. 807-809
-
-
O'Callaghan, N.1
Dhillon, V.2
Thomas, P.3
Fenech, M.4
-
18
-
-
33646488931
-
Real-time pcr assay for measurement of mouse telomeres
-
Callicott RJ, Womack JE. Real-time PCR assay for measurement of mouse telomeres. Comp Med. 2006;56(1):17-22.
-
(2006)
Comp Med
, vol.56
, Issue.1
, pp. 17-22
-
-
Callicott, R.J.1
Womack, J.E.2
-
19
-
-
2342419515
-
Telomere measurement by quantitative pcr
-
Cawthon RM. Telomere measurement by quantitative PCR. Nucleic Acids Res. 2002;30(10):e47.
-
(2002)
Nucleic Acids Res
, vol.30
, Issue.10
-
-
Cawthon, R.M.1
-
20
-
-
0037063361
-
Telomere maintenance in telomerase-positive human ovarian skov-3 cells cannot be retarded by complete inhibition of telomerase
-
Gan Y, Mo Y, Johnston J, Lu J, Wientjes MG, Au JL. Telomere maintenance in telomerase-positive human ovarian SKOV-3 cells cannot be retarded by complete inhibition of telomerase. FEBS Lett. 2002; 527(1-3):10-14.
-
(2002)
FEBS Lett
, vol.527
, Issue.1-3
, pp. 10-14
-
-
Gan, Y.1
Mo, Y.2
Johnston, J.3
Lu, J.4
Wientjes, M.G.5
Au, J.L.6
-
21
-
-
69949114447
-
Type and frequency of idh1 and idh2 mutations are related to astrocytic and oligodendroglial differentiation and age: A study of 1,010 diffuse gliomas
-
Hartmann C, Meyer J, Balss J, et al. Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas. Acta Neuropathol. 2009;118(4):469-474.
-
(2009)
Acta Neuropathol
, vol.118
, Issue.4
, pp. 469-474
-
-
Hartmann, C.1
Meyer, J.2
Balss, J.3
-
22
-
-
33750432843
-
Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from Gruppo Italiano Cooperativo di Neuro-oncologia (GICNO)
-
Brandes AA, Tosoni A, Cavallo G, et al. Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from Gruppo Italiano Cooperativo di Neuro-oncologia (GICNO). Br J Cancer. 2006;95(9):1155-1160.
-
(2006)
Br J Cancer
, vol.95
, Issue.9
, pp. 1155-1160
-
-
Brandes, A.A.1
Tosoni, A.2
Cavallo, G.3
-
23
-
-
12144291692
-
Clinical trial substantiates the predictive value of o-6-methylguanine- dna methyltransferase promoter methylation in glioblastoma patients treated with temozolomide
-
Hegi ME, Diserens AC, Godard S, et al. Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin Cancer Res. 2004;10(6):1871-1874.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.6
, pp. 1871-1874
-
-
Hegi, M.E.1
Diserens, A.C.2
Godard, S.3
-
24
-
-
77953291279
-
Prognostic value of o6-methylguanine-dna methyltransferase status in glioblastoma patients, assessed by five different methods
-
Karayan-Tapon L, Quillien V, Guilhot J, et al. Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods. J Neurooncol. 2009;97(3):311-322.
-
(2009)
J Neurooncol
, vol.97
, Issue.3
, pp. 311-322
-
-
Karayan-Tapon, L.1
Quillien, V.2
Guilhot, J.3
-
25
-
-
80055032902
-
The cdkn2a g500 allele is more frequent in gbm patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival
-
Royds JA, Al Nadaf S, Wiles AK, et al. The CDKN2A G500 allele is more frequent in GBM patients with no defined telomere maintenance mechanism tumors and is associated with poorer survival. PLoS One. 2011;6(10):e26737.
-
(2011)
PLoS One
, vol.6
, Issue.10
-
-
Royds, J.A.1
Al Nadaf, S.2
Wiles, A.K.3
-
26
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science. 1994;266(5193):2011-2015.
-
(1994)
Science
, vol.266
, Issue.5193
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
-
27
-
-
33745679352
-
Telomerase therapeutics for cancer: Challenges and new directions
-
Shay JW, Wright WE. Telomerase therapeutics for cancer: challenges and new directions. Nat Rev Drug Discov. 2006;5(7):577-584.
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.7
, pp. 577-584
-
-
Shay, J.W.1
Wright, W.E.2
-
28
-
-
0031776901
-
Telomerase expression in gliomas including the nonastrocytic tumors
-
Chong EY, Lam PY, Poon WS, Ng HK. Telomerase expression in gliomas including the nonastrocytic tumors. Hum Pathol. 1998;29(6):599-603.
-
(1998)
Hum Pathol
, vol.29
, Issue.6
, pp. 599-603
-
-
Chong, E.Y.1
Lam, P.Y.2
Poon, W.S.3
Ng, H.K.4
-
29
-
-
0032523944
-
Telomerase activity and alterations in telomere length in human brain tumors
-
Hiraga S, Ohnishi T, Izumoto S, et al. Telomerase activity and alterations in telomere length in human brain tumors. Cancer Res. 1998;58(10):2117-2125.
-
(1998)
Cancer Res
, vol.58
, Issue.10
, pp. 2117-2125
-
-
Hiraga, S.1
Ohnishi, T.2
Izumoto, S.3
-
30
-
-
0344541118
-
Telomerase activity in human gliomas
-
Le S, Zhu JJ, Anthony DC, Greider CW, Black PM. Telomerase activity in human gliomas. Neurosurgery. 1998;42(5):1120-1124.
-
(1998)
Neurosurgery
, vol.42
, Issue.5
, pp. 1120-1124
-
-
Le S Zhu, J.J.1
Anthony, D.C.2
Greider, C.W.3
Black, P.M.4
-
31
-
-
0031590419
-
Expression of telomerase rna, telomerase activity, and telomere length in human gliomas
-
Morii K, Tanaka R, Onda K, Tsumanuma I, Yoshimura J. Expression of telomerase RNA, telomerase activity, and telomere length in human gliomas. Biochem Biophys Res Commun. 1997;239(3): 830-834.
-
(1997)
Biochem Biophys Res Commun
, vol.239
, Issue.3
, pp. 830-834
-
-
Morii, K.1
Tanaka, R.2
Onda, K.3
Tsumanuma, I.4
Yoshimura, J.5
-
32
-
-
0031982328
-
Telomerase activity in 144 brain tumours
-
Sano T, Asai A, Mishima K, Fujimaki T, Kirino T. Telomerase activity in 144 brain tumours. Br J Cancer. 1998;77(10):1633-1637.
-
(1998)
Br J Cancer
, vol.77
, Issue.10
, pp. 1633-1637
-
-
Sano, T.1
Asai, A.2
Mishima, K.3
Fujimaki, T.4
Kirino, T.5
-
33
-
-
80054014431
-
Telomere length is a prognostic factor for overall survival in colorectal cancer
-
Valls C, Pinol C, Rene JM, Buenestado J, Vinas J. Telomere length is a prognostic factor for overall survival in colorectal cancer. Colorectal Dis. 2011;13(11):1265-1272.
-
(2011)
Colorectal Dis
, vol.13
, Issue.11
, pp. 1265-1272
-
-
Valls, C.1
Pinol, C.2
Rene, J.M.3
Buenestado, J.4
Vinas, J.5
-
34
-
-
80053229934
-
Prevalence of the alternative lengthening of telomeres: Telomere maintenance mechanism in human cancer subtypes
-
Heaphy CM, Subhawong AP, Hong SM, et al. Prevalence of the alternative lengthening of telomeres: telomere maintenance mechanism in human cancer subtypes. Am J Pathol. 2011;179(4): 1608-1615.
-
(2011)
Am J Pathol
, vol.179
, Issue.4
, pp. 1608-1615
-
-
Heaphy, C.M.1
Subhawong, A.P.2
Hong, S.M.3
-
35
-
-
77954751638
-
Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival
-
McDonald KL, McDonnell J, Muntoni A, et al. Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival. J Neuropathol Exp Neurol. 2010;69(7):729-736.
-
(2010)
J Neuropathol Exp Neurol
, vol.69
, Issue.7
, pp. 729-736
-
-
McDonald, K.L.1
McDonnell, J.2
Muntoni, A.3
-
36
-
-
0030862763
-
The significant role of telomerase activity in human brain tumors
-
Nakatani K, Yoshimi N, Mori H, et al. The significant role of telomerase activity in human brain tumors. Cancer. 1997;80(3):471-476.
-
(1997)
Cancer
, vol.80
, Issue.3
, pp. 471-476
-
-
Nakatani, K.1
Yoshimi, N.2
Mori, H.3
-
37
-
-
47349129485
-
Different assessments of immunohistochemically stained ki-67 and htert in glioblastoma multiforme yield variable results: A study with reference to survival prognosis
-
Persson A, Englund E. Different assessments of immunohistochemically stained Ki-67 and hTERT in glioblastoma multiforme yield variable results: a study with reference to survival prognosis. Clin Neuropathol. 2008;27(4):224-233.
-
(2008)
Clin Neuropathol
, vol.27
, Issue.4
, pp. 224-233
-
-
Persson, A.1
Englund, E.2
-
38
-
-
27944476391
-
Expression of transcription factor e2f1 and telomerase in glioblastomas: Mechanistic linkage and prognostic significance
-
Alonso MM, Fueyo J, Shay JW, et al. Expression of transcription factor E2F1 and telomerase in glioblastomas: mechanistic linkage and prognostic significance. J Natl Cancer Inst. 2005;97(21):1589-1600.
-
(2005)
J Natl Cancer Inst
, vol.97
, Issue.21
, pp. 1589-1600
-
-
Alonso, M.M.1
Fueyo, J.2
Shay, J.W.3
-
39
-
-
0037058657
-
Prediction of clinical course of diffusely infiltrating astrocytomas from telomerase expression and quantitated activity level
-
Fukushima T, Yoshino A, Katayama Y, Watanabe T, Kusama K, Moro I. Prediction of clinical course of diffusely infiltrating astrocytomas from telomerase expression and quantitated activity level. Cancer Lett. 2002;187(1-2):191-198.
-
(2002)
Cancer Lett
, vol.187
, Issue.1-2
, pp. 191-198
-
-
Fukushima, T.1
Yoshino, A.2
Katayama, Y.3
Watanabe, T.4
Kusama, K.5
Moro, I.6
-
40
-
-
19944428332
-
A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas
-
Henson JD, Hannay JA, McCarthy SW, et al. A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas. Clin Cancer Res. 2005;11(1):217-225.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.1
, pp. 217-225
-
-
Henson, J.D.1
Hannay, J.A.2
McCarthy, S.W.3
-
41
-
-
33749534161
-
Telomeres and telomerase: The path from maize tetrahymena and yeast to human cancer and aging
-
Blackburn EH, Greider CW, Szostak JW. Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med. 2006;12(10):1133-1138.
-
(2006)
Nat Med
, vol.12
, Issue.10
, pp. 1133-1138
-
-
Blackburn, E.H.1
Greider, C.W.2
Szostak, J.W.3
-
42
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in pdgfra, idh1, egfr, and nf1
-
Verhaak RG, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer. 2010;17(1):98-110.
-
(2010)
Cancer
, vol.17
, Issue.1
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
43
-
-
39649094505
-
Inhibition of telomerase in the endothelial cells disrupts tumor angiogenesis in glioblastoma xenografts
-
Falchetti ML, Mongiardi MP, Fiorenzo P, et al. Inhibition of telomerase in the endothelial cells disrupts tumor angiogenesis in glioblastoma xenografts. Int J Cancer. 2008;122(6):1236-1242.
-
(2008)
Int J Cancer
, vol.122
, Issue.6
, pp. 1236-1242
-
-
Falchetti, M.L.1
Mongiardi, M.P.2
Fiorenzo, P.3
-
44
-
-
0038756365
-
Glioblastoma induces vascular endothelial cells to express telomerase in vitro
-
Falchetti ML, Pierconti F, Casalbore P, et al. Glioblastoma induces vascular endothelial cells to express telomerase in vitro. Cancer Res. 2003;63(13):3750-4.
-
(2003)
Cancer Res
, vol.63
, Issue.13
, pp. 37504
-
-
Falchetti, M.L.1
Pierconti, F.2
Casalbore, P.3
-
45
-
-
1542306071
-
Telomerase as a growth-promoting factor
-
Gorbunova V, Seluanov A. Telomerase as a growth-promoting factor. Cell Cycle. 2003;2(6):534-537.
-
(2003)
Cell Cycle
, vol.2
, Issue.6
, pp. 534-537
-
-
Gorbunova, V.1
Seluanov, A.2
-
46
-
-
79953013144
-
Alternative lengthening of telomeres in human glioma stem cells
-
Silvestre DC, Pineda JR, Hoffschir F, et al. Alternative lengthening of telomeres in human glioma stem cells. Stem Cells. 2011;29(3):440-451.
-
(2011)
Stem Cells
, vol.29
, Issue.3
, pp. 440-451
-
-
Silvestre, D.C.1
Pineda, J.R.2
Hoffschir, F.3
|