Alterations in c-Src/HER1 and estrogen receptor α signaling pathways in mammary gland and tumors of hexachlorobenzene-treated rats

Toxicology

Volumn 293, Issue 1-3, 2012, Pages 68-77

  Peña, Delfina ^a   Pontillo, Carolina ^a   García, María Alejandra ^a   Cocca, Claudia ^a   Alvarez, Laura ^a   Chiappini, Florencia ^a   Bourguignon, Nadia ^b   Frahm, Isabel ^c   Bergoc, Rosa ^a   Kleiman de Pisarev, Diana ^a   Randi, Andrea ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

^c Sanatorio Mater Dei   (Argentina)

Author keywords

C Src; Estrogen receptor ; HER1; Hexachlorobenzene; Mammary gland; Tumor promotion

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FOLLITROPIN; HEXACHLOROBENZENE; HORMONE; LUTEINIZING HORMONE; METHYLNITROSOUREA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PESTICIDE; PROGESTERONE; PROLACTIN; STAT5B PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST TUMOR; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; HISTOPATHOLOGY; HORMONE BLOOD LEVEL; MAMMARY GLAND; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; TUMOR;

ANIMALS; COCARCINOGENESIS; ENDOCRINE DISRUPTORS; ESTROGEN RECEPTOR ALPHA; FEMALE; GONADAL STEROID HORMONES; HEXACHLOROBENZENE; HUMANS; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; NEOPLASM PROTEINS; PESTICIDES; PHOSPHORYLATION; PITUITARY HORMONES, ANTERIOR; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

RATTUS; RODENTIA;

EID: 84857045260     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.12.012     Document Type: Article

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