Ultrasound-sensitive siRNA-loaded nanobubbles formed by hetero-assembly of polymeric micelles and liposomes and their therapeutic effect in gliomas

Biomaterials

Volumn 34, Issue 18, 2013, Pages 4532-4543

  Yin, Tinghui ^a,b   Wang, Ping ^a   Li, Jingguo ^b   Zheng, Rongqin ^a   Zheng, Bowen ^a   Cheng, Du ^b   Li, Ruitang ^c   Lai, Jieyi ^c   Shuai, Xintao ^b,c  

^a THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; Cavitation; Nanobubbles; RNA interfering; SIRT2; Ultrasound

Indexed keywords

CANCER CELL APOPTOSIS; DELIVERY VECTOR; NANOBUBBLES; POLYMERIC MICELLE; RNA INTERFERENCE; SIRT2; THERAPEUTIC EFFECTS; TUMOR TREATMENT;

CAVITATION; CELL DEATH; DRUG DELIVERY; FUNCTIONAL POLYMERS; GENETIC ENGINEERING; LIPOSOMES; MICELLES; MOLECULAR BIOLOGY; RNA; TUMORS; ULTRASONICS;

GENE THERAPY;

COPOLYMER; LIPOSOME; MACROGOL; NANOBUBBLE; PHOSPHOLIPID; POLYLYSINE; POLYMER; SIRTUIN 2; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG STABILITY; FLOW CYTOMETRY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; GLIOMA; GLIOMA CELL; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; LIPOSOMAL DELIVERY; MICELLE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; TUMOR MODEL; ULTRASOUND; WESTERN BLOTTING; ZETA POTENTIAL;

ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ELECTROPHORESIS, AGAR GEL; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENE TRANSFER TECHNIQUES; GLIOMA; LIPOSOMES; MICE; MICE, NUDE; MICELLES; MICROBUBBLES; NANOPARTICLES; POLYMERS; RATS; RNA, SMALL INTERFERING; SIRTUIN 2; TRANSFECTION; ULTRASONICS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS MUSCULUS;

EID: 84875615823     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.02.067     Document Type: Article

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