Grape seed and skin extract alleviates high-fat diet-induced renal lipotoxicity and prevents copper depletion in rat

Applied Physiology, Nutrition and Metabolism

Volumn 38, Issue 3, 2013, Pages 259-267

  Charradi, Kamel ^a,b   Elkahoui, Salem ^a   Karkouch, Ines ^a   Limam, Ferid ^a   Hamdaoui, Ghaith ^a   Hassine, Fethy Ben ^c   El May, Michèle Veronique ^d   May, Ahmed El ^d   Aouani, Ezzedine ^a,b  

^a CENTRE DE BIOTECHNOLOGIE DE BORJ CÉDRIA   (Tunisia)

^b UNIVERSITY OF CARTHAGE   (Tunisia)

^c Polyclinique de la CNSS d'El Khadra   (Tunisia)

^d Unité de recherche no 01 UR 07 08   (Tunisia)

Author keywords

Copper; Grape polyphenols; Kidney; Obesity; Oxidative stress

Indexed keywords

COPPER;

ANIMAL; DRUG EFFECTS; LIPID DIET; OXIDATIVE STRESS; PLANT SEED; RAT; VITIS; WISTAR RAT;

ANIMALS; COPPER; DIET, HIGH-FAT; OXIDATIVE STRESS; RATS; RATS, WISTAR; SEEDS; VITIS;

EID: 84875610417     PISSN: 17155312     EISSN: 17155320     Source Type: Journal    
DOI: 10.1139/apnm-2012-0416     Document Type: Article

References (48)

1. Aebi, H. 1974. Methods of enzymatic analysis. 2nd ed. Chemia Weinheium. NewYork, N.Y., USA.
2. Bagchi, D., Ray, S.D., Patel, D., and Bagchi, M. 2001. Protection against drug and chemical-induced multi-organ toxicity by a novel IH636 grape seed proanthocyanidin extract. Drugs Exp. Clin. Res. 27(1): 3-15. PMID:11276828.
3. Batista, M.N., Cuppari, L., de Fátima Campos Pedrosa, L., Almeida, M.G., de Almeida, J.B., de Medeiros, A.C., et al. 2006. Effect of end-stage renal disease and diabetes on zinc and copper status. Biol. Trace Elem. Res. 112(1): 1-12. doi:10.1385/BTER:112:1:1. PMID:16943612.
4. Bebe, F.N., and Panemangalore, M. 2009. Biosafety of flavonoids in rats: effects on copper and zinc homeostasis and interaction with low level pesticide exposure. Biol. Trace Elem. Res. 129(1-3): 200-212. doi:10.1007/s12011-008-8289-2. PMID:19099207.
5. Bettaieb, I., Bourgou, S., Sriti, J., Msaada, K., Limam, F., and Marzouk, B. 2011. Essential oils and fatty acids composition of tunisian and indian cumin seeds: a comparative study. J. Sci. Food Agric. 91(11): 2100-2107. doi:10.1002/jsfa.4513. PMID:21681765.
6. Bladé, C., Arola, L., and Salvadó, M.J. 2010. Hypolipidemic effects of proanthocyanidins and their underlying biochemical and molecular mechanisms. Mol. Nutr. Food Res. 54(1): 37-59. doi:10.1002/mnfr.200900476. PMID: 19960459.
7. Bobulescu, I.A. 2010. Renal lipid metabolism and lipotoxicity. Curr. Opin. Nephrol. Hypertens. 19(4): 393-402. doi:10.1097/MNH.0b013e32833aa4ac. PMID:20489613.
8. Charradi, K., Sebai, H., Elkahoui, S., Ben Hassine, F., Limam, F., and Aouani, E. 2011. Grape Seed Extract Alleviates High-Fat Diet-Induced Obesity and Heart Dysfunction by Preventing Cardiac Siderosis. Cardiovasc. Toxicol. 11(1): 28-37. doi:10.1007/s12012-010-9101-z. PMID:21234706.
9. Charradi, K., Elkahoui, S., Karkouch, I., Limam, F., Ben Hassine, F., and Aouani, E. 2012. Grape Seed and Skin Extract Prevents High-Fat Diet-Induced BrainLipotoxicityinRat. Neurochem. Res.37(9):2004-2013. doi:10.1007/s11064-012-0821-2. PMID:22684284.
10. Chen, J., Muntner, P., Hamm, L.L., Jones, D.W., Batuman, V., Fonseca, V., et al. 2004. The metabolic syndrome and chronic kidney disease in US adults. Ann. Intern. Med. 140(3): 167-174. PMID:14757614.
11. Chen, J., Gu, D., Chen, C.S., Wu, X., Hamm, L.L., Muntner, P., et al. 2007. Association between the metabolic syndrome and chronic kidney disease in Chinese adults. Nephrol. Dial. Transplant. 22(4): 1100-1106. doi:10.1093/ndt/ gfl759. PMID:17272313.
12. Chung, H.W., Lim, J.H., Kim, M.Y., Shin, S.J., Chung, S., Choi, B.S., et al. 2012. High-fat diet-induced renal cell apoptosis and oxidative stress in spontaneously hypertensive rat are ameliorated by fenofibrate through the PPAR_-FoxO3a-PGC-1_ pathway. Nephrol. Dial. Transplant. 27(6): 2213-2225. doi:10. 1093/ndt/gfr613. PMID:22076434.
13. Cockcroft, D.W., and Gault, M.H. 1976. Prediction of creatinine from serum creatinine. Nephron, 16(1): 31-41. doi:10.1159/000180580. PMID:1244564.
14. Draper, H.H., and Hadley, M. 1990. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 186: 421-431. doi:10.1016/0076-6879(90)86135-I. PMID:2233309.
15. Ellman, GL. 1959. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82(1): 70-77. doi:10.1016/0003-9861(59)90090-6. PMID:13650640.
16. Erdely, A., Freshaur, G., Maddox, D.A., Olson, J.L., Samsell, L., and Baylis, C. 2004. Renal disease in rats with type 2 diabetes is associated with decreased renal NO production. Diabetologia, 47(10): 1672-1676. doi:10.1007/s00125-004-1509-1. PMID:15490111.
17. FDA. 2011. Agency Response Letter GRAS Notice No. GRN 000124. Available from http://www.fda.gov/Food/FoodIngredientsPackaging/Generally RecognizedasSafeGRAS/GRASListings/ucm153940.htm. [Accessed 1 June 2011.]
18. Ferruzzi, M.G., Lobo, J.K., Janle, E.M., Cooper, B., Simon, J.E., Wu, Q.L., et al. 2009. Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease. J. Alzheimers Dis. 18(1):113-124. PMID:19625746.
19. Folch, J., Lees, M., and Sloane Stanley, G.H. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226(1): 497-509. PMID:13428781.
20. Green, L.C., Wagner, D.A., Glogowski, J., Skipper, P.L., Wishnok, J.S., and Tannenbaum, S.R. 1982. Analysis of nitrate, nitrite and [15 N] nitrate in biological fluids. Anal. Biochem. 126(1): 131-138. doi:10.1016/0003-2697(82)90118-X. PMID:7181105.
21. Hartree, E.F. 1972. Determination of protein: a modification of the Lowry method that gives a linear photometric response. Anal. Biochem. 48(2): 422-427. doi:10.1016/0003-2697(72)90094-2. PMID:4115981.
22. 2 release by the treatment of human blood polymorphonuclear leucocytes with myristate. J. Biochem. 86(1): 87-95. PMID:479132.
23. Kambham, N., Markowitz, G.S., Valeri, A.M., Lin, J., and D'Agati, V.D. 2001. Obesity related glomerulopathy: an emerging epidemic. Kidney Int. 59(4): 1498-1509. doi:10.1046/j.1523-1755.2001.0590041498.x. PMID:11260414.
24. Kasiske, B.L., O'Donnell, M.P., Cleary, M.P., and Keane, W.F. 1988. Treatment of hyperlipidemia reduces glomerular injury in obese Zucker rats. Kidney Int. 33(3): 667-672. doi:10.1038/ki.1988.51. PMID:3367557.
25. Khanal, R.C., Howard, L.R., and Prior, R.L. 2009. Procyanidin content of grape seed and pomace and total anthocyanin content of grape pomace as affected by extrusion processing. J. Food Sci. 74(6): H174-H182. doi:10.1111/j.1750-3841. 2009.01221.x. PMID:19723202.
26. Krol, E., Krejpcia, Z., and Chrmurzynck, A. 2011. Folic acid and protein content in maternal diet and post-natal high fat feeding affect the tissue levels of iron, zinc and copper in the rat. Biol. Trace Elem. Res. 144(1-3): 885-893. doi:10. 1007/s12011-011-9048-3. PMID:21484405.
27. Leardi, A., Caraglia, M., Selleri, C., Pepe, S., Pizzi, C., and Notaro, R. 1998. Desferioxamine increases iron depletion and apoptosis induced by ara-C of human myeloid leukaemic cells. Br. J. Haematol. 102(3): 746-752. doi:10.1046/j.1365-2141.1998.00834.x. PMID:9722302.
28. Levine, R.L., Garland, D., Oliver, C.N., Amici, A., Climent, I., and Lenz, A.G. 1990. Determination of carbonyl content in oxidatevely modified proteins. Methods Enzymol. 186: 467-478. PMID:1978225.
29. Listenberger, L.L., Han, X., Lewis, S.E., Cases, S., Farese, R.V., Jr., Ory, D.S., et al. 2003. Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc. Natl. Acad. Sci. U.S.A. 100(6): 3077-3082. doi:10.1073/pnas. 0630588100. PMID:12629214.
30. Misra, H.P., and Fridovich, I. 1972. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 247(10): 3170-3175. PMID:4623845.
31. Mohanasundari, M., Sabesan, M., and Sethupathy, S. 2005. Renoprotective effect of grape seed extract in ethylene glycol induced nephrotoxic mice. Indian J. Exp. Biol. 43(4): 356-359. PMID:15875721.
32. Nakamura, K., Hosada, S., and Hayashi, K. 1974. Purification and proprieties of rat liver glutathione peroxidase. Biochem. Biophys. Acta, 358: 251-261. doi: 10.1016/0005-2744(74)90455-0.
33. Nandakumar, V., Singh, T., and Katiyar, S.K. 2008. Multi-targeted prevention and therapy of cancer by proanthocyanidins. Cancer Lett. 269(2): 378-387. doi:10. 1016/j.canlet.2008.03.049. PMID:18457915.
34. National Research Council. 1985. Guide for the care and the use of laboratory animals. National Institute of Health, Bethesda, Md., USA. 20: 85.
35. Nicholson, A.C., Febbraio, M., Han, J., Silverstein, R.L., and Hajjar, D.P. 2000. CD36 in atherosclerosis: the role of a class B macrophage scavenger receptor. Ann. N.Y. Acad. Sci. 902: 128-131. doi:10.1111/j.1749-6632.2000.tb06307.x. PMID:10865832.
36. Pan, S.Y., Desmeules, M., Morrison, H., and Wen, S.W. 2006. Obesity, high energy intake, lack of physical activity and the risk of kidney cancer. Cancer Epidemiol. Biomarkers Prev. 15: 2453-2460. doi:10.1158/1055-9965.EPI-06-0616. PMID:17164370.
37. Salem, N.A., and Salem, E.A. 2011. Renoprotective effect of grape seed extract against oxidative stress induced by gentamycin and hypercholesterolemia in rats. Ren. Fail. 33(8): 824-832. doi:10.3109/0886022X.2011.601832. PMID: 21787152.
38. Schaffer, J.E. 2003. Lipotoxicity: when tissues overeat. Curr. Opin. Lipidol. 14(3): 281-287. doi:10.1097/00041433-200306000-00008. PMID:12840659.
39. Serrano, J., Puupponen-Pimiä, R., Dauer, A., Aura, A.M., and Saura-Calixto, F. 2009. Tannins: current knowledge of food sources, intake, bioavailability and biological effects. Mol. Nutr. Food Res. 53(Suppl. 2): S310-S329. doi:10.1002/ mnfr.200900039. PMID:19437486.
40. Shetty, A.K., Kumar, G.S., Sambaiah, K., and Salimath, P.V. 2005. Effect of bitter gourd (Momordica charantia) on glycaemic status in streptozotocin induced diabetic rats. Plant Foods. Hum. Nutr. 60(3): 109-112. doi:10.1007/s11130-005-6837-x. PMID:16187012.
41. Stern, J., and Lewis, W.H. 1957. The colorimetric estimation of calcium in serum with ocresolphthalein complexone. Clin. Chim. Acta, 2(6): 576-580. PMID: 13500593.
42. Unger, R.H. 2002. Lipotoxic diseases. Annu. Rev. Med. 53: 319-336. doi:10.1146/ annurev.med.53.082901.104057. PMID:11818477.
43. Unger, R.H., and Orci, L. 2001. Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J. 15(2): 312-321. doi:10.1096/fj.00-0590. PMID:11156947.
44. Wahba, I.M., and Mak, R.H. 2007. Obesity and obesity-initiated metabolic syndrome: mechanistic links to chronic kidney disease. Clin. J. Am. Soc. Nephrol. 2(3): 550-556. doi:10.2215/CJN.04071206. PMID:17699463.
45. Wang, Y.F., Hodgkinson, V., Zhu, S., Weisman, G.A., and Petris, M.J. 2011. Advances in the understanding of mammalian copper transporters. Adv. Nutr. 2(2): 129-137. doi:10.3945/an.110.000273. PMID:22332042.
46. Wei, R., Ding, R., Wang, Y., and Tang, L. 2011. Grape seed proanthocyanidin extract reduces renal ischemia/reperfusion injuries in rat. Am. J. Med. Sci. 343(6): 452-457. doi:10.1097/MAJ.0b013e31823315f7. PMID:22157385.
47. Weinberg, J.M. 2006. Lipotoxicity. Kidney Int. 70(9): 1560-1566. doi:10.1038/sj.ki. 5001834. PMID:16955100.
48. Worthington Biochemical Corporation. 1977. Worthington Enzyme Manual. Worthington Biochemical Corp., Freehold, N.J., USA. pp. 74-75.