Is aldehyde dehydrogenase 2 a credible genetic instrument for alcohol use in mendelian randomization analysis in southern Chinese men?

International Journal of Epidemiology

Volumn 42, Issue 1, 2013, Pages 318-328

  Yeung, Shiu Lun Au ^a   Jiang, ChaoQiang ^b   Cheng, Kar Keung ^c   Liu, Bin ^b   Zhang, WeiSen ^b   Lam, Tai Hing ^a   Leung, Gabriel M ^a   Schooling, C Mary ^a,d  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b Guangzhou No 12 Hospital   (China)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Aldehyde dehydrogenase 2; Chinese men; Mendelian randomization

Indexed keywords

ALANINE AMINOTRANSFERASE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ALCOHOL; ALDEHYDE; BLOOD; CARDIOVASCULAR DISEASE; ENZYME ACTIVITY; GENETIC ANALYSIS; GENOTYPE; HEALTH RISK; PHYSICAL ACTIVITY; POLYMORPHISM; RISK FACTOR; SOCIOECONOMIC CONDITIONS;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHINA; COGNITION; DIASTOLIC BLOOD PRESSURE; ECONOMIC ASPECT; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; GLUCOSE BLOOD LEVEL; HUMAN; LIVER FUNCTION; MAJOR CLINICAL STUDY; MALE; MENDELIAN RANDOMIZATION ANALYSIS; MINI MENTAL STATE EXAMINATION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RISK FACTOR; SCORING SYSTEM; SELF REPORT; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SOCIAL ASPECT; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; ALDEHYDE DEHYDROGENASE; ANALYSIS OF VARIANCE; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; COHORT STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINEAR MODELS; MALE; MENDELIAN RANDOMIZATION ANALYSIS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; SOCIOECONOMIC FACTORS;

CHINA;

EID: 84875594574     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dys221     Document Type: Article

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