Mitochondrial aldehyde dehydrogenase polymorphism is not associated with incidence of Alzheimer's disease

International Journal of Geriatric Psychiatry

Volumn 20, Issue 11, 2005, Pages 1075-1080

  Shin, Il Seon ^a,b   Stewart, Robert ^c   Kim, Jae Min ^a,d   Kim, Sung Wan ^b   Yang, Su Jin ^d   Shin, Hee Young ^d   Jung, Jae Sung ^e   Yoon, Jin Sang ^a,d  

^a Chonnam National University Medical School   (South Korea)

^b Chonnam National University   (South Korea)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d Chonnam National University Medical School   (South Korea)

^e Sunchon National University   (South Korea)

Author keywords

Alcoholism; Alzheimer disease; Apolipoprotein E; Cognitive decline; Dementia; Mitochondrial aldehyde dehydrogenase

Indexed keywords

ALCOHOL; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; APOLIPOPROTEIN E4; MITOCHONDRIAL ENZYME;

AGED; ALCOHOL CONSUMPTION; ALCOHOLISM; ALLELE; ALZHEIMER DISEASE; ARTICLE; CLINICAL EXAMINATION; COGNITION; CORRELATION ANALYSIS; DEMOGRAPHY; DRINKING BEHAVIOR; ENZYME POLYMORPHISM; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENOTYPE; HEALTH SURVEY; HUMAN; INCIDENCE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PROTEIN PROTEIN INTERACTION;

AGED; ALCOHOLISM; ALDEHYDE DEHYDROGENASE; ALZHEIMER DISEASE; ANALYSIS OF VARIANCE; APOLIPOPROTEINS E; COGNITION DISORDERS; DEMENTIA; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, GENETIC; PSYCHIATRIC STATUS RATING SCALES;

EID: 28444440321     PISSN: 08856230     EISSN: None     Source Type: Journal    
DOI: 10.1002/gps.1401     Document Type: Article

References (25)

1. American Psychiatric Association. 1994. Diagnostic and Statistical Manual of Mental Disorders, 4th edn. American Psychiatric Press: Washington DC.
2. Choi JY. 1988. Korean Dementia Rating Scale. Hackjisa: Seoul.
3. Evans DA, Beckett LA, Field TS, et al. 1997. Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons. JAMA 277: 822-824.
4. Goedde HW, Agarwal DP, Harada S, et al. 1983. Population Genetic studies on aldehyde dehydrogenase isozyme deficiency and alcohol sensitivity. Am J Hum Genet 35: 769-772.
5. Goedde HW, Agarwal DP, Fritze G, et al. 1992. Distrubution of ADH2 and ALDH2 genotypes in different populations. Hum Genet 88: 344-346.
6. Higuchi S, Matsushita S, Murayama M, Takagi S, Hayashida M. 1995. Alcohol and aldehyde dehydrogenase polymorphisms and the risk for alcoholism. Am J Psychiatry 152: 1219-1221.
7. Higuchi S, Matsushita S, Muramatsu T, Murayama M, Hayashida M. 1996. Alcohol and aldehyde dehydrogenase genotypes and drinking behavior in Japanese. Alcohol Clin Exp Res 20: 493-497.
8. Hughes CP, Berg L, Danziger WL, Cohen LA, Martin RL. 1982. A new clinical scale for the staging of dementia. Br J Psychiatry 140: 566-572.
9. Jagger C, Andersen K, Breteler MM, et al. 2000. Prognosis with dementia in Europe: a collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 54(Suppl. 5): S16-S20.
10. Kamino K, Nagasaka K, Imagawa M, et al. 2000. Deficiency in mitochondrial aldehyde dehydrogenase increases the risk for late-onset Alzheimer's disease in the Japanese population. Biochem Biophys Res Commun 273: 192-196.
11. Kim JM, Stewart R, Shin IS, Jung JS, Yoon JS. 2004a. Assessment of association between mitochondrial aldehyde dehydrogenase polymorphisin and Alzheimer's disease in an older Korean population. Neurobiol Aging 25: 295-301.
12. Kim JM, Stewart R, Shin IS, Yoon IS. 2004b. Vascular disease/risk and late-life Depression in a Korean community population. Br J Psychiatry 185: 102-107.
13. Lawton MP, Brody EM. 1969. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 9: 179-186.
14. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. 1984. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34: 939-944.
15. Murayama M, Matsushita S, Muramatsu T, Higuchi S. 1998. Clinical characteristics and disease course of alcoholics with inactive aldehyde dehydrogenase-2. Alcohol Clin Exp Res 22: 524-527.
16. National Institute of Alcohol Abuse and Alcoholism. 1995. The Physicians' Guide to Helping Patients with Alcohol Problems. National Institutes of Health publication: Bethesda; 95-3769.
17. Ohta S, Ohsawa I, Kamino K, Ando F, Shimokata H. 2004. Mitochondrial ALDH2 deficiency as an oxidative stress. Ann NY Acad Sci 1011: 36-44.
18. Park JH, Kwon YC. 1990. Modification of the mini-mental state examination for use in the elderly in a non-western society. Part I: Development of Korean version of Mini-Mental State Examination. Int J Geriatr Psychiatry 5: 381-387.
19. Prince M, Acosta D, Chiu H, Scazufca M, Varghese M, and the 10/66 Dementia Research Group. 2003. Dementia diagnosis in developing countries: a cross-cultural validation study. Lancet 361: 909-917.
20. Rosen J, Colantonio A, Becker JT, Lopez OL, DeKosky ST, Moss HB. 1993. Effect of a history of heavy alcohol consumption on Alzheimer's disease. Br J Psychiatry 163: 358-363.
21. Takeshita T, Morimoto K, Mao X, Hashimoto T, Furuyama J. 1994. Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population. Hum Genet 94: 217-223.
22. Thomasson HR, Edenberg HJ, Crabb DW, et al. 1991. Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet 48: 677-681.
23. Wallerstedt S, Denison H, Sandstrom J, Westin J. 1995. The prevalence of alcoholism and its relation to cause of hospitalization and long-term mortality in male somatic inpatients. J Intern Med 237: 339-344.
24. Zivelin A, Rosenberg N, Peretz H, Amit Y, Kornbrot N, Seligsohn U. 1997. Improved method for genotyping apolipoprotein E polymorphins by a PCR-based assay simultaneously utilizing two distinct restriction enzymes. Clin Chem 43: 1657-1659.
25. + neurotoxicity and delays its elimination from the striatum. Brain Res 501: 11-22.