-
1
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J, et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993; 362: 841-4.
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
-
2
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe JA, Jiang BH, Iyer NV, et al. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 1996; 16: 4604-13.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
-
3
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-42.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
4
-
-
20544471876
-
Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
-
Kabbinavar FF, Hambleton J, Mass RD, et al. Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 2005; 23: 3706-12.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3706-3712
-
-
Kabbinavar, F.F.1
Hambleton, J.2
Mass, R.D.3
-
5
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
-
Saltz LB, Clarke S, Diaz-Rubio E, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008; 26: 2013-19.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Diaz-Rubio, E.3
-
6
-
-
0001650010
-
Induction of sarcoma in the rat by iron-dextran complex
-
Richmond HG,. Induction of sarcoma in the rat by iron-dextran complex. Br Med J 1959; 1: 947-9.
-
(1959)
Br Med J
, vol.1
, pp. 947-949
-
-
Richmond, H.G.1
-
7
-
-
0024343207
-
Induction of mesothelioma by intraperitoneal injections of ferric saccharate in male Wistar rats
-
Okada S, Hamazaki S, Toyokuni S, et al. Induction of mesothelioma by intraperitoneal injections of ferric saccharate in male Wistar rats. Br J Cancer 1989; 60: 708-11.
-
(1989)
Br J Cancer
, vol.60
, pp. 708-711
-
-
Okada, S.1
Hamazaki, S.2
Toyokuni, S.3
-
8
-
-
35448952080
-
Long-term phlebotomy with low-iron diet therapy lowers risk of development of hepatocellular carcinoma from chronic hepatitis C
-
Kato J, Miyanishi K, Kobune M, et al. Long-term phlebotomy with low-iron diet therapy lowers risk of development of hepatocellular carcinoma from chronic hepatitis C. J Gastroenterol 2007; 42: 830-6.
-
(2007)
J Gastroenterol
, vol.42
, pp. 830-836
-
-
Kato, J.1
Miyanishi, K.2
Kobune, M.3
-
9
-
-
0023681960
-
Iron nutrition and tumor growth: Decreased tumor growth in iron-deficient mice
-
Hann HW, Stahlhut MW, Blumberg BS,. Iron nutrition and tumor growth: decreased tumor growth in iron-deficient mice. Cancer Res 1988; 48: 4168-70.
-
(1988)
Cancer Res
, vol.48
, pp. 4168-4170
-
-
Hann, H.W.1
Stahlhut, M.W.2
Blumberg, B.S.3
-
10
-
-
0033984404
-
Severe anemia is associated with poor tumor oxygenation in head and neck squamous cell carcinomas
-
Becker A, Stadler P, Lavey RS, et al. Severe anemia is associated with poor tumor oxygenation in head and neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys 2000; 46: 459-66.
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.46
, pp. 459-466
-
-
Becker, A.1
Stadler, P.2
Lavey, R.S.3
-
11
-
-
0345707572
-
Oxygenation gain factor: A novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers
-
Vaupel P, Mayer A, Briest S, et al. Oxygenation gain factor: a novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers. Cancer Res 2003; 63: 7634-7.
-
(2003)
Cancer Res
, vol.63
, pp. 7634-7637
-
-
Vaupel, P.1
Mayer, A.2
Briest, S.3
-
12
-
-
0033621939
-
Topological analysis of p21WAF1/CIP1 expression in esophageal squamous dysplasia
-
Shirakawa Y, Naomoto Y, Kimura M, et al. Topological analysis of p21WAF1/CIP1 expression in esophageal squamous dysplasia. Clin Cancer Res 2000; 6: 541-50.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 541-550
-
-
Shirakawa, Y.1
Naomoto, Y.2
Kimura, M.3
-
13
-
-
33847118123
-
Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models
-
Chang YS, Adnane J, Trail PA, et al. Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models. Cancer Chemother Pharmacol 2007; 59: 561-74.
-
(2007)
Cancer Chemother Pharmacol
, vol.59
, pp. 561-574
-
-
Chang, Y.S.1
Adnane, J.2
Trail, P.A.3
-
14
-
-
76649102745
-
RHuEPo reduces ischemia-reperfusion injury and improves survival after transplantation of fatty livers in rats
-
Schmeding M, Rademacher S, Boas-Knoop S, et al. rHuEPo reduces ischemia-reperfusion injury and improves survival after transplantation of fatty livers in rats. Transplantation 2010; 89: 161-8.
-
(2010)
Transplantation
, vol.89
, pp. 161-168
-
-
Schmeding, M.1
Rademacher, S.2
Boas-Knoop, S.3
-
15
-
-
73349106542
-
Prognostic significance of vascular endothelial growth factor in squamous cell carcinomas of the tonsil in relation to human papillomavirus status and epidermal growth factor receptor
-
Fei J, Hong A, Dobbins TA, et al. Prognostic significance of vascular endothelial growth factor in squamous cell carcinomas of the tonsil in relation to human papillomavirus status and epidermal growth factor receptor. Ann Surg Oncol 2009; 16: 2908-17.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 2908-2917
-
-
Fei, J.1
Hong, A.2
Dobbins, T.A.3
-
16
-
-
0035952360
-
Evaluation of the anti-tumor and anti-angiogenic effect of paclitaxel and thalidomide on the xenotransplanted oral squamous cell carcinoma
-
Myoung H, Hong SD, Kim YY, et al. Evaluation of the anti-tumor and anti-angiogenic effect of paclitaxel and thalidomide on the xenotransplanted oral squamous cell carcinoma. Cancer Lett 2001; 163: 191-200.
-
(2001)
Cancer Lett
, vol.163
, pp. 191-200
-
-
Myoung, H.1
Hong, S.D.2
Kim, Y.Y.3
-
17
-
-
38949116994
-
Establishment of biological and pharmacokinetic assays of telomerase-specific replication-selective adenovirus
-
Hashimoto Y, Watanabe Y, Shirakiya Y, et al. Establishment of biological and pharmacokinetic assays of telomerase-specific replication-selective adenovirus. Cancer Sci. 2008; 99: 385-90.
-
(2008)
Cancer Sci.
, vol.99
, pp. 385-390
-
-
Hashimoto, Y.1
Watanabe, Y.2
Shirakiya, Y.3
-
18
-
-
79959208568
-
Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells
-
Ohara T, Takaoka M, Toyooka S, et al. Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells. Cancer Sci 2011; 102: 1344-9.
-
(2011)
Cancer Sci
, vol.102
, pp. 1344-1349
-
-
Ohara, T.1
Takaoka, M.2
Toyooka, S.3
-
19
-
-
0023543356
-
Serum transferrin receptor as a new index of erythropoiesis
-
Kohgo Y, Niitsu Y, Kondo H, et al. Serum transferrin receptor as a new index of erythropoiesis. Blood 1987; 70: 1955-8.
-
(1987)
Blood
, vol.70
, pp. 1955-1958
-
-
Kohgo, Y.1
Niitsu, Y.2
Kondo, H.3
-
20
-
-
33751169387
-
Hypoxia-inducible factor-1 (HIF-1)
-
Ke Q, Costa M,. Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol 2006; 70: 1469-80.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1469-1480
-
-
Ke, Q.1
Costa, M.2
-
21
-
-
66149176908
-
Erlotinib and bevacizumab have synergistic activity against melanoma
-
Schicher N, Paulitschke V, Swoboda A, et al. Erlotinib and bevacizumab have synergistic activity against melanoma. Clin Cancer Res 2009; 15: 3495-3502.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3495-3502
-
-
Schicher, N.1
Paulitschke, V.2
Swoboda, A.3
-
22
-
-
57849167858
-
Treatment of resistant human colon cancer xenografts by a fluoxetine-doxorubicin combination enhances therapeutic responses comparable to an aggressive bevacizumab regimen
-
Argov M, Kashi R, Peer D, et al. Treatment of resistant human colon cancer xenografts by a fluoxetine-doxorubicin combination enhances therapeutic responses comparable to an aggressive bevacizumab regimen. Cancer Lett 2009; 274: 118-25.
-
(2009)
Cancer Lett
, vol.274
, pp. 118-125
-
-
Argov, M.1
Kashi, R.2
Peer, D.3
-
23
-
-
0029165446
-
Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability
-
Shima DT, Deutsch U, D'Amore PA,. Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability. FEBS Lett 1995; 370: 203-8.
-
(1995)
FEBS Lett
, vol.370
, pp. 203-208
-
-
Shima, D.T.1
Deutsch, U.2
D'Amore, P.A.3
-
24
-
-
0036115163
-
Scientists and clinicians test their metal-back to the future with platinum compounds
-
Guminski AD, Harnett PR, deFazio A,. Scientists and clinicians test their metal-back to the future with platinum compounds. Lancet Oncol 2002; 3: 312-8.
-
(2002)
Lancet Oncol
, vol.3
, pp. 312-318
-
-
Guminski, A.D.1
Harnett, P.R.2
Defazio, A.3
-
25
-
-
78650236850
-
Chemotherapy, chemoresistance and the changing treatment landscape for NSCLC
-
Chang A,. Chemotherapy, chemoresistance and the changing treatment landscape for NSCLC. Lung Cancer 2011; 71: 3-10.
-
(2011)
Lung Cancer
, vol.71
, pp. 3-10
-
-
Chang, A.1
-
26
-
-
36048939391
-
The cost-effectiveness of bevacizumab in the first-line treatment of metastatic colorectal cancer in England and Wales
-
Tappenden P, Jones R, Paisley S, et al. The cost-effectiveness of bevacizumab in the first-line treatment of metastatic colorectal cancer in England and Wales. Eur J Cancer 2007; 43: 2487-94.
-
(2007)
Eur J Cancer
, vol.43
, pp. 2487-2494
-
-
Tappenden, P.1
Jones, R.2
Paisley, S.3
-
27
-
-
84859105892
-
A cost-benefit analysis of bevacizumab in combination with paclitaxel in the first-line treatment of patients with metastatic breast cancer
-
Montero AJ, Avancha K, Gluck S, et al. A cost-benefit analysis of bevacizumab in combination with paclitaxel in the first-line treatment of patients with metastatic breast cancer. Breast Cancer Res Treat 2012; 132: 747-51.
-
(2012)
Breast Cancer Res Treat
, vol.132
, pp. 747-751
-
-
Montero, A.J.1
Avancha, K.2
Gluck, S.3
-
28
-
-
65349129409
-
The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1
-
Ohyashiki JH, Kobayashi C, Hamamura R, et al. The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1. Cancer Sci 2009; 100: 970-77.
-
(2009)
Cancer Sci
, vol.100
, pp. 970-977
-
-
Ohyashiki, J.H.1
Kobayashi, C.2
Hamamura, R.3
-
29
-
-
34548675357
-
Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: A possible relationship with polyamine metabolism
-
Lescoat G, Chantrel-Groussard K, Pasdeloup N, et al. Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism. Cell Prolif 2007; 40: 755-67.
-
(2007)
Cell Prolif
, vol.40
, pp. 755-767
-
-
Lescoat, G.1
Chantrel-Groussard, K.2
Pasdeloup, N.3
-
30
-
-
0033500248
-
Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: A bridge to the clinic
-
Hoffman, RM,. Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: a bridge to the clinic. Invest New Drugs 1999; 17: 343-59.
-
(1999)
Invest New Drugs
, vol.17
, pp. 343-359
-
-
Hoffman, R.M.1
-
31
-
-
25844461626
-
The multiple uses of fluorescent proteins to visualize cancer in vivo
-
Hoffman, RM,. The multiple uses of fluorescent proteins to visualize cancer in vivo. Nat Rev Cancer 2005; 5: 796-806.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 796-806
-
-
Hoffman, R.M.1
-
32
-
-
33748649107
-
Color-coded fluorescence imaging of tumor-host interactions
-
Hoffman RM, Yang M,. Color-coded fluorescence imaging of tumor-host interactions. Nat Protoc 2006; 1: 928-35.
-
(2006)
Nat Protoc
, vol.1
, pp. 928-935
-
-
Hoffman, R.M.1
Yang, M.2
-
33
-
-
20444507605
-
Nestin-linked green fluorescent protein transgenic nude mouse for imaging human tumor angiogenesis
-
Amoh Y, Yang M, Li L, et al. Nestin-linked green fluorescent protein transgenic nude mouse for imaging human tumor angiogenesis. Cancer Res 2005; 65: 5352-7.
-
(2005)
Cancer Res
, vol.65
, pp. 5352-5357
-
-
Amoh, Y.1
Yang, M.2
Li, L.3
-
34
-
-
33646086718
-
Dual-color imaging of nascent blood vessels vascularizing pancreatic cancer in an orthotopic model demonstrates antiangiogenesis efficacy of gemcitabine
-
Amoh Y, Li L, Tsuji K, et al. Dual-color imaging of nascent blood vessels vascularizing pancreatic cancer in an orthotopic model demonstrates antiangiogenesis efficacy of gemcitabine. J Surg Res 2006; 132: 164-9.
-
(2006)
J Surg Res
, vol.132
, pp. 164-169
-
-
Amoh, Y.1
Li, L.2
Tsuji, K.3
-
35
-
-
33845961014
-
Bevacizumab: An angiogenesis inhibitor for the treatment of solid malignancies
-
Shih T, Lindley C,. Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies. Clin Ther 2006; 28: 1779-1802.
-
(2006)
Clin Ther
, vol.28
, pp. 1779-1802
-
-
Shih, T.1
Lindley, C.2
-
36
-
-
58949099316
-
Targeting angiogenesis in the treatment of lung cancer
-
Wheatley-Price P, Shepherd FA,. Targeting angiogenesis in the treatment of lung cancer. J Thorac Oncol 2008; 3: 1173-84.
-
(2008)
J Thorac Oncol
, vol.3
, pp. 1173-1184
-
-
Wheatley-Price, P.1
Shepherd, F.A.2
-
37
-
-
78649537524
-
Biomarkers to predict the clinical efficacy of bevacizumab in cancer
-
Jubb AM, Harris AL,. Biomarkers to predict the clinical efficacy of bevacizumab in cancer. Lancet Oncol 2010; 11: 1172-83.
-
(2010)
Lancet Oncol
, vol.11
, pp. 1172-1183
-
-
Jubb, A.M.1
Harris, A.L.2
-
38
-
-
20344407540
-
Colorectal cancer and antiangiogenic therapy: What can be expected in clinical practice?
-
Mancuso A, Sternberg CN,. Colorectal cancer and antiangiogenic therapy: what can be expected in clinical practice? Crit Rev Oncol Hematol 2005; 55: 67-81.
-
(2005)
Crit Rev Oncol Hematol
, vol.55
, pp. 67-81
-
-
Mancuso, A.1
Sternberg, C.N.2
-
39
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
-
Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009; 45: 228-47.
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
|