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Volumn 77, Issue 4, 2013, Pages 886-892

Left ventricular stiffening as therapeutic target for heart failure with preserved ejection fraction

Author keywords

Diastolic dysfunction; Heart failure; Ventricular function

Indexed keywords

ACYL COENZYME A DESATURASE 1; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GUANOSINE PHOSPHATE; MATRIX METALLOPROTEINASE; MINERALOCORTICOID ANTAGONIST;

EID: 84875551912     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-13-0214     Document Type: Review
Times cited : (23)

References (68)
  • 1
    • 53249090182 scopus 로고    scopus 로고
    • ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: The task force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology: Developed in collaboration with the heart failure association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)
    • Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: The task force for the diagnosis and treatment of acute and chronic heart failure 2008 of the European Society of Cardiology: Developed in collaboration with the heart failure association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur Heart J 2008; 29: 2388-2442.
    • (2008) Eur Heart J , vol.29 , pp. 2388-2442
    • Dickstein, K.1    Cohen-Solal, A.2    Filippatos, G.3    McMurray, J.J.4    Ponikowski, P.5    Poole-Wilson, P.A.6
  • 3
    • 70349948833 scopus 로고    scopus 로고
    • Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction: Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
    • Tsuchihashi-Makaya M, Hamaguchi S, Kinugawa S, Yokota T, Goto D, Yokoshiki H, et al. Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction: Report from the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD). Circ J 2009; 73: 1893-1900.
    • (2009) Circ J , vol.73 , pp. 1893-1900
    • Tsuchihashi-Makaya, M.1    Hamaguchi, S.2    Kinugawa, S.3    Yokota, T.4    Goto, D.5    Yokoshiki, H.6
  • 4
    • 33746033433 scopus 로고    scopus 로고
    • Outcome of heart failure with preserved ejection fraction in a population-based study
    • Bhatia RS, Tu JV, Lee DS, Austin PC, Fang J, Haouzi A, et al. Outcome of heart failure with preserved ejection fraction in a population-based study. N Engl J Med 2006; 355: 260-269.
    • (2006) N Engl J Med , vol.355 , pp. 260-269
    • Bhatia, R.S.1    Tu, J.V.2    Lee, D.S.3    Austin, P.C.4    Fang, J.5    Haouzi, A.6
  • 5
    • 0028609956 scopus 로고
    • Systolic and diastolic dysfunction in patients with clinical diagnosis of dilated cardiomyopathy: Relation to symptoms and prognosis
    • Rihal CS, Nishimura RA, Hatle LK, Bailey KR, Tajik AJ. Systolic and diastolic dysfunction in patients with clinical diagnosis of dilated cardiomyopathy: Relation to symptoms and prognosis. Circulation 1994; 90: 2772-2779.
    • (1994) Circulation , vol.90 , pp. 2772-2779
    • Rihal, C.S.1    Nishimura, R.A.2    Hatle, L.K.3    Bailey, K.R.4    Tajik, A.J.5
  • 6
    • 67649845466 scopus 로고    scopus 로고
    • Heart failure with preserved ejection fraction: Is it due to contractile dysfunction?: Reply
    • Yamamoto K, Sakata Y, Ohtani T, Takeda Y, Mano T. Heart failure with preserved ejection fraction: Is it due to contractile dysfunction?: Reply. Circ J 2009; 73: 1170.
    • (2009) Circ J , vol.73 , pp. 1170
    • Yamamoto, K.1    Sakata, Y.2    Ohtani, T.3    Takeda, Y.4    Mano, T.5
  • 7
    • 3843094224 scopus 로고    scopus 로고
    • Diastolic heart failure: Abnormalities in active relaxation and passive stiffness of the left ventricle
    • Zile MR, Baicu CF, Gaasch WH. Diastolic heart failure: Abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med 2004; 350: 1953-1959.
    • (2004) N Engl J Med , vol.350 , pp. 1953-1959
    • Zile, M.R.1    Baicu, C.F.2    Gaasch, W.H.3
  • 8
    • 0024553925 scopus 로고
    • Determinants of left ventricular filling and of the diastolic pressure-volume relation
    • Gilbert JC, Glantz SA. Determinants of left ventricular filling and of the diastolic pressure-volume relation. Circ Res 1989; 64: 827-852.
    • (1989) Circ Res , vol.64 , pp. 827-852
    • Gilbert, J.C.1    Glantz, S.A.2
  • 9
    • 0021273901 scopus 로고
    • Assessment of diastolic function: Suggested methods and future considerations
    • Mirsky I. Assessment of diastolic function: Suggested methods and future considerations. Circulation 1984; 69: 836-841.
    • (1984) Circulation , vol.69 , pp. 836-841
    • Mirsky, I.1
  • 10
    • 33646231760 scopus 로고    scopus 로고
    • Current perspectives in diastolic dysfunction and diastolic heart failure
    • Leite-Moreira AF. Current perspectives in diastolic dysfunction and diastolic heart failure. Heart 2006; 92: 712-718.
    • (2006) Heart , vol.92 , pp. 712-718
    • Leite-Moreira, A.F.1
  • 11
    • 13944260131 scopus 로고    scopus 로고
    • Role of impaired myocardial relaxation in the production of elevated left ventricular filling pressure
    • Hay I, Rich J, Ferber P, Burkhoff D, Maurer MS. Role of impaired myocardial relaxation in the production of elevated left ventricular filling pressure. Am J Physiol Heart Circ Physiol 2005; 288: H1203-H1208.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Hay, I.1    Rich, J.2    Ferber, P.3    Burkhoff, D.4    Maurer, M.S.5
  • 12
    • 0033974788 scopus 로고    scopus 로고
    • Development of different phenotypes of hypertensive heart failure: Systolic versus diastolic failure in Dahl salt-sensitive rats
    • Doi R, Masuyama T, Yamamoto K, Doi Y, Mano T, Sakata Y, et al. Development of different phenotypes of hypertensive heart failure: Systolic versus diastolic failure in Dahl salt-sensitive rats. J Hypertens 2000; 18: 111-120.
    • (2000) J Hypertens , vol.18 , pp. 111-120
    • Doi, R.1    Masuyama, T.2    Yamamoto, K.3    Doi, Y.4    Mano, T.5    Sakata, Y.6
  • 13
    • 0033673331 scopus 로고    scopus 로고
    • Evolving changes in Doppler mitral flow velocity pattern in rats with hypertensive hypertrophy
    • Masuyama T, Yamamoto K, Sakata Y, Doi R, Nishikawa N, Kondo H, et al. Evolving changes in Doppler mitral flow velocity pattern in rats with hypertensive hypertrophy. J Am Coll Cardiol 2000; 36: 2333-2338.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 2333-2338
    • Masuyama, T.1    Yamamoto, K.2    Sakata, Y.3    Doi, R.4    Nishikawa, N.5    Kondo, H.6
  • 14
    • 0035165597 scopus 로고    scopus 로고
    • Renin angiotensin system-dependent hypertrophy as a contributor to heart failure in hypertensive rats: Different characteristics from renin angiotensin system-independent hypertrophy
    • Sakata Y, Masuyama T, Yamamoto K, Doi R, Mano T, Kuzuya T, et al. Renin angiotensin system-dependent hypertrophy as a contributor to heart failure in hypertensive rats: Different characteristics from renin angiotensin system-independent hypertrophy. J Am Coll Cardiol 2001; 37: 293-299.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 293-299
    • Sakata, Y.1    Masuyama, T.2    Yamamoto, K.3    Doi, R.4    Mano, T.5    Kuzuya, T.6
  • 15
    • 0037371828 scopus 로고    scopus 로고
    • Temocapril prevents transition to diastolic heart failure in rats even if initiated after appearance of LV hypertrophy and diastolic dysfunction
    • Sakata Y, Yamamoto K, Mano T, Nishikawa N, Yoshida J, Miwa T, et al. Temocapril prevents transition to diastolic heart failure in rats even if initiated after appearance of LV hypertrophy and diastolic dysfunction. Cardiovasc Res 2003; 57: 757-765.
    • (2003) Cardiovasc Res , vol.57 , pp. 757-765
    • Sakata, Y.1    Yamamoto, K.2    Mano, T.3    Nishikawa, N.4    Yoshida, J.5    Miwa, T.6
  • 16
    • 23744500968 scopus 로고    scopus 로고
    • Assessment of systolic and diastolic ventricular properties via pressure-volume analysis: A guide for clinical, translational, and basic researchers
    • Burkhoff D, Mirsky I, Suga H. Assessment of systolic and diastolic ventricular properties via pressure-volume analysis: A guide for clinical, translational, and basic researchers. Am J Physiol Heart Circ Physiol 2005; 289: H501-H512.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Burkhoff, D.1    Mirsky, I.2    Suga, H.3
  • 17
    • 0017262145 scopus 로고
    • Assessment of passive elastic stiffness of cardiac muscle: Mathematical concepts, physiologic and clinical considerations, directions of future research
    • Mirsky I. Assessment of passive elastic stiffness of cardiac muscle: Mathematical concepts, physiologic and clinical considerations, directions of future research. Prog Cardiovasc Dis 1976; 18: 277-308.
    • (1976) Prog Cardiovasc Dis , vol.18 , pp. 277-308
    • Mirsky, I.1
  • 18
    • 34548525319 scopus 로고    scopus 로고
    • How to diagnose diastolic heart failure: A consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the heart failure and echocardiography associations of the European Society of Cardiology
    • Paulus WJ, Tschope C, Sanderson JE, Rusconi C, Flachskampf FA, Rademakers FE, et al. How to diagnose diastolic heart failure: A consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the heart failure and echocardiography associations of the European Society of Cardiology. Eur Heart J 2007; 28: 2539-2550.
    • (2007) Eur Heart J , vol.28 , pp. 2539-2550
    • Paulus, W.J.1    Tschope, C.2    Sanderson, J.E.3    Rusconi, C.4    Flachskampf, F.A.5    Rademakers, F.E.6
  • 19
    • 0030741179 scopus 로고    scopus 로고
    • Evaluation of diastolic filling of left ventricle in health and disease: Doppler echocardiography is the clinician's rosetta stone
    • Nishimura RA, Tajik AJ. Evaluation of diastolic filling of left ventricle in health and disease: Doppler echocardiography is the clinician's rosetta stone. J Am Coll Cardiol 1997; 30: 8-18.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 8-18
    • Nishimura, R.A.1    Tajik, A.J.2
  • 20
    • 0030698732 scopus 로고    scopus 로고
    • Doppler tissue imaging: A noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressures
    • Nagueh SF, Middleton KJ, Kopelen HA, Zoghbi WA, Quinones MA. Doppler tissue imaging: A noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressures. J Am Coll Cardiol 1997; 30: 1527-1533.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 1527-1533
    • Nagueh, S.F.1    Middleton, K.J.2    Kopelen, H.A.3    Zoghbi, W.A.4    Quinones, M.A.5
  • 21
    • 0032192138 scopus 로고    scopus 로고
    • New doppler echocardiographic applications for the study of diastolic function
    • Garcia MJ, Thomas JD, Klein AL. New doppler echocardiographic applications for the study of diastolic function. J Am Coll Cardiol 1998; 32: 865-875.
    • (1998) J Am Coll Cardiol , vol.32 , pp. 865-875
    • Garcia, M.J.1    Thomas, J.D.2    Klein, A.L.3
  • 22
    • 0034633812 scopus 로고    scopus 로고
    • Clinical utility of doppler echocardiography and tissue doppler imaging in the estimation of left ventricular filling pressures: A comparative simultaneous Doppler-catheterization study
    • Ommen SR, Nishimura RA, Appleton CP, Miller FA, Oh JK, Redfield MM, et al. Clinical utility of doppler echocardiography and tissue doppler imaging in the estimation of left ventricular filling pressures: A comparative simultaneous Doppler-catheterization study. Circulation 2000; 102: 1788-1794.
    • (2000) Circulation , vol.102 , pp. 1788-1794
    • Ommen, S.R.1    Nishimura, R.A.2    Appleton, C.P.3    Miller, F.A.4    Oh, J.K.5    Redfield, M.M.6
  • 24
    • 37349007866 scopus 로고    scopus 로고
    • Evaluation of left ventricular filling pressures by Doppler echocardiography in patients with hypertrophic cardiomyopathy: Correlation with direct left atrial pressure measurement at cardiac catheterization
    • Geske JB, Sorajja P, Nishimura RA, Ommen SR. Evaluation of left ventricular filling pressures by Doppler echocardiography in patients with hypertrophic cardiomyopathy: Correlation with direct left atrial pressure measurement at cardiac catheterization. Circulation 2007; 116: 2702-2708.
    • (2007) Circulation , vol.116 , pp. 2702-2708
    • Geske, J.B.1    Sorajja, P.2    Nishimura, R.A.3    Ommen, S.R.4
  • 26
    • 79960815921 scopus 로고    scopus 로고
    • Assessment of left ventricular diastolic function: The power, possibilities, and pitfalls of echocardiographic imaging techniques
    • Ogunyankin KO. Assessment of left ventricular diastolic function: The power, possibilities, and pitfalls of echocardiographic imaging techniques. Can J Cardiol 2011; 27: 311-318.
    • (2011) Can J Cardiol , vol.27 , pp. 311-318
    • Ogunyankin, K.O.1
  • 27
    • 59149090582 scopus 로고    scopus 로고
    • Noninvasive assessment of wall distensibility with the evaluation of diastolic epicardial movement
    • Takeda Y, Sakata Y, Higashimori M, Mano T, Nishio M, Ohtani T, et al. Noninvasive assessment of wall distensibility with the evaluation of diastolic epicardial movement. J Card Fail 2009; 15: 68-77.
    • (2009) J Card Fail , vol.15 , pp. 68-77
    • Takeda, Y.1    Sakata, Y.2    Higashimori, M.3    Mano, T.4    Nishio, M.5    Ohtani, T.6
  • 28
    • 79952326407 scopus 로고    scopus 로고
    • Transition from asymptomatic diastolic dysfunction to heart failure with preserved ejection fraction: Roles of systolic function and ventricular distensibility
    • Aizawa Y, Sakata Y, Mano T, Takeda Y, Ohtani T, Tamaki S, et al. Transition from asymptomatic diastolic dysfunction to heart failure with preserved ejection fraction: Roles of systolic function and ventricular distensibility. Circ J 2011; 75: 596-602.
    • (2011) Circ J , vol.75 , pp. 596-602
    • Aizawa, Y.1    Sakata, Y.2    Mano, T.3    Takeda, Y.4    Ohtani, T.5    Tamaki, S.6
  • 29
    • 79957865729 scopus 로고    scopus 로고
    • Competing risks of heart failure with preserved ejection fraction in diabetic patients
    • Takeda Y, Sakata Y, Mano T, Ohtani T, Kamimura D, Tamaki S, et al. Competing risks of heart failure with preserved ejection fraction in diabetic patients. Eur J Heart Fail 2011; 13: 664-669.
    • (2011) Eur J Heart Fail , vol.13 , pp. 664-669
    • Takeda, Y.1    Sakata, Y.2    Mano, T.3    Ohtani, T.4    Kamimura, D.5    Tamaki, S.6
  • 30
    • 84867182258 scopus 로고    scopus 로고
    • Diastolic stiffness as assessed by diastolic wall strain is associated with adverse remodelling and poor outcomes in heart failure with preserved ejection fraction
    • Ohtani T, Mohammed SF, Yamamoto K, Dunlay SM, Weston SA, Sakata Y, et al. Diastolic stiffness as assessed by diastolic wall strain is associated with adverse remodelling and poor outcomes in heart failure with preserved ejection fraction. Eur Heart J 2012; 33: 1742-1749.
    • (2012) Eur Heart J , vol.33 , pp. 1742-1749
    • Ohtani, T.1    Mohammed, S.F.2    Yamamoto, K.3    Dunlay, S.M.4    Weston, S.A.5    Sakata, Y.6
  • 31
    • 33646132038 scopus 로고    scopus 로고
    • Development of Heart failure in chronic hypertensive dahl rats: Focus on heart failure with preserved ejection fraction
    • Klotz S, Hay I, Zhang G, Maurer M, Wang J, Burkhoff D. Development of Heart failure in chronic hypertensive dahl rats: Focus on heart failure with preserved ejection fraction. Hypertension 2006; 47: 901-911.
    • (2006) Hypertension , vol.47 , pp. 901-911
    • Klotz, S.1    Hay, I.2    Zhang, G.3    Maurer, M.4    Wang, J.5    Burkhoff, D.6
  • 32
    • 4444349039 scopus 로고    scopus 로고
    • Clinical practice: Diastolic heart failure
    • Aurigemma GP, Gaasch WH. Clinical practice: Diastolic heart failure. N Engl J Med 2004; 351: 1097-1105.
    • (2004) N Engl J Med , vol.351 , pp. 1097-1105
    • Aurigemma, G.P.1    Gaasch, W.H.2
  • 33
    • 12144289732 scopus 로고    scopus 로고
    • Left ventricular concentric geometry during treatment adversely affects cardiovascular prognosis in hypertensive patients
    • Muiesan ML, Salvetti M, Monteduro C, Bonzi B, Paini A, Viola S, et al. Left ventricular concentric geometry during treatment adversely affects cardiovascular prognosis in hypertensive patients. Hypertension 2004; 43: 731-738.
    • (2004) Hypertension , vol.43 , pp. 731-738
    • Muiesan, M.L.1    Salvetti, M.2    Monteduro, C.3    Bonzi, B.4    Paini, A.5    Viola, S.6
  • 34
    • 79952829685 scopus 로고    scopus 로고
    • Heart failure with preserved ejection fraction: Pathophysiology, diagnosis, and treatment
    • Borlaug BA, Paulus WJ. Heart failure with preserved ejection fraction: Pathophysiology, diagnosis, and treatment. Eur Heart J 2011; 32: 670-679.
    • (2011) Eur Heart J , vol.32 , pp. 670-679
    • Borlaug, B.A.1    Paulus, W.J.2
  • 35
    • 80054948842 scopus 로고    scopus 로고
    • Prognostic impact of myocardial interstitial fibrosis in nonischemic heart failure: Comparison between preserved and reduced ejection fraction heart failure
    • Aoki T, Fukumoto Y, Sugimura K, Oikawa M, Satoh K, Nakano M, et al. Prognostic impact of myocardial interstitial fibrosis in nonischemic heart failure: Comparison between preserved and reduced ejection fraction heart failure. Circ J 2011; 75: 2605-2613.
    • (2011) Circ J , vol.75 , pp. 2605-2613
    • Aoki, T.1    Fukumoto, Y.2    Sugimura, K.3    Oikawa, M.4    Satoh, K.5    Nakano, M.6
  • 36
    • 0036272927 scopus 로고    scopus 로고
    • Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart
    • Yamamoto K, Masuyama T, Sakata Y, Nishikawa N, Mano T, Yoshida J, et al. Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart. Cardiovasc Res 2002; 55: 76-82.
    • (2002) Cardiovasc Res , vol.55 , pp. 76-82
    • Yamamoto, K.1    Masuyama, T.2    Sakata, Y.3    Nishikawa, N.4    Mano, T.5    Yoshida, J.6
  • 37
    • 0035499027 scopus 로고    scopus 로고
    • Long-term administration of amlodipine prevents decompensation to diastolic heart failure in hypertensive rats
    • Nishikawa N, Masuyama T, Yamamoto K, Sakata Y, Mano T, Miwa T, et al. Long-term administration of amlodipine prevents decompensation to diastolic heart failure in hypertensive rats. J Am Coll Cardiol 2001; 38: 1539-1545.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 1539-1545
    • Nishikawa, N.1    Masuyama, T.2    Yamamoto, K.3    Sakata, Y.4    Mano, T.5    Miwa, T.6
  • 38
    • 0042887401 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor blockade prevents diastolic heart failure through modulation of Ca(2+) regulatory proteins and extracellular matrix
    • Sakata Y, Yamamoto K, Mano T, Nishikawa N, Yoshida J, Nakayama H, et al. Angiotensin II type 1 receptor blockade prevents diastolic heart failure through modulation of Ca(2+) regulatory proteins and extracellular matrix. J Hypertens 2003; 21: 1737-1745.
    • (2003) J Hypertens , vol.21 , pp. 1737-1745
    • Sakata, Y.1    Yamamoto, K.2    Mano, T.3    Nishikawa, N.4    Yoshida, J.5    Nakayama, H.6
  • 39
    • 0037371849 scopus 로고    scopus 로고
    • Differential activation of matrix metalloproteinases in heart failure with and without ventricular dilatation
    • Nishikawa N, Yamamoto K, Sakata Y, Mano T, Yoshida J, Miwa T, et al. Differential activation of matrix metalloproteinases in heart failure with and without ventricular dilatation. Cardiovasc Res 2003; 57: 766-774.
    • (2003) Cardiovasc Res , vol.57 , pp. 766-774
    • Nishikawa, N.1    Yamamoto, K.2    Sakata, Y.3    Mano, T.4    Yoshida, J.5    Miwa, T.6
  • 40
    • 33646439273 scopus 로고    scopus 로고
    • Matrix metalloproteinases/tissue inhibitors of metalloproteinases: Relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease
    • Ahmed SH, Clark LL, Pennington WR, Webb CS, Bonnema DD, Leonardi AH, et al. Matrix metalloproteinases/tissue inhibitors of metalloproteinases: Relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease. Circulation 2006; 113: 2089-2096.
    • (2006) Circulation , vol.113 , pp. 2089-2096
    • Ahmed, S.H.1    Clark, L.L.2    Pennington, W.R.3    Webb, C.S.4    Bonnema, D.D.5    Leonardi, A.H.6
  • 41
    • 77952958509 scopus 로고    scopus 로고
    • Filling pressures and collagen metabolism in hypertensive patients with heart failure and normal ejection fraction
    • Gonzalez A, Lopez B, Querejeta R, Zubillaga E, Echeverria T, Diez J. Filling pressures and collagen metabolism in hypertensive patients with heart failure and normal ejection fraction. Hypertension 2010; 55: 1418-1424.
    • (2010) Hypertension , vol.55 , pp. 1418-1424
    • Gonzalez, A.1    Lopez, B.2    Querejeta, R.3    Zubillaga, E.4    Echeverria, T.5    Diez, J.6
  • 42
    • 24044527140 scopus 로고    scopus 로고
    • Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart
    • Heymans S, Schroen B, Vermeersch P, Milting H, Gao F, Kassner A, et al. Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart. Circulation 2005; 112: 1136-1144.
    • (2005) Circulation , vol.112 , pp. 1136-1144
    • Heymans, S.1    Schroen, B.2    Vermeersch, P.3    Milting, H.4    Gao, F.5    Kassner, A.6
  • 43
    • 0027285976 scopus 로고
    • Tissue renin-angiotensin system in myocardial hypertrophy and failure
    • Dzau VJ. Tissue renin-angiotensin system in myocardial hypertrophy and failure. Arch Intern Med 1993; 153: 937-942.
    • (1993) Arch Intern Med , vol.153 , pp. 937-942
    • Dzau, V.J.1
  • 44
    • 0032788508 scopus 로고    scopus 로고
    • Angiotensin II receptor antagonists: An emerging new class of cardiovascular therapeutics
    • Timmermans PB. Angiotensin II receptor antagonists: An emerging new class of cardiovascular therapeutics. Hypertens Res 1999; 22: 147-153.
    • (1999) Hypertens Res , vol.22 , pp. 147-153
    • Timmermans, P.B.1
  • 45
    • 0343674735 scopus 로고    scopus 로고
    • Treatment of hypertension with perindopril reduces plasma atrial natriuretic peptide levels, left ventricular mass, and improves echocardiographic parameters of diastolic function
    • Yalcin F, Aksoy FG, Muderrisoglu H, Sabah I, Garcia MJ, Thomas JD. Treatment of hypertension with perindopril reduces plasma atrial natriuretic peptide levels, left ventricular mass, and improves echocardiographic parameters of diastolic function. Clin Cardiol 2000; 23: 437-441.
    • (2000) Clin Cardiol , vol.23 , pp. 437-441
    • Yalcin, F.1    Aksoy, F.G.2    Muderrisoglu, H.3    Sabah, I.4    Garcia, M.J.5    Thomas, J.D.6
  • 46
    • 0037188574 scopus 로고    scopus 로고
    • Losartan-dependent regression of myocardial fibrosis is associated with reduction of left ventricular chamber stiffness in hypertensive patients
    • Diez J, Querejeta R, Lopez B, Gonzalez A, Larman M, Martinez Ubago JL. Losartan-dependent regression of myocardial fibrosis is associated with reduction of left ventricular chamber stiffness in hypertensive patients. Circulation 2002; 105: 2512-2517.
    • (2002) Circulation , vol.105 , pp. 2512-2517
    • Diez, J.1    Querejeta, R.2    Lopez, B.3    Gonzalez, A.4    Larman, M.5    Martinez Ubago, J.L.6
  • 48
    • 0041408234 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: The CHARMPRESERVED trial
    • Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJV, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: The CHARMPRESERVED trial. Lancet 2003; 362: 777-781.
    • (2003) Lancet , vol.362 , pp. 777-781
    • Yusuf, S.1    Pfeffer, M.A.2    Swedberg, K.3    Granger, C.B.4    Held, P.5    McMurray, J.J.V.6
  • 50
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure: Randomized aldactone evaluation study investigators
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure: Randomized aldactone evaluation study investigators. N Engl J Med 1999; 341: 709-717.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6
  • 51
    • 33846820432 scopus 로고    scopus 로고
    • Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: Beneficial effects of mineralocorticoid receptor blocker
    • Ohtani T, Ohta M, Yamamoto K, Mano T, Sakata Y, Nishio M, et al. Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: Beneficial effects of mineralocorticoid receptor blocker. Am J Physiol Regul Integr Comp Physiol 2007; 292: R946-R954.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292
    • Ohtani, T.1    Ohta, M.2    Yamamoto, K.3    Mano, T.4    Sakata, Y.5    Nishio, M.6
  • 52
    • 84875513232 scopus 로고    scopus 로고
    • Aldosterone antagonists and outcomes in real-world older patients with heart failure and preserved ejection fraction
    • Patel K, Fonarow GC, Kitzman DW, Aban IB, Love TE, Allman RM, et al. Aldosterone antagonists and outcomes in real-world older patients with heart failure and preserved ejection fraction. JACC Heart Fail 2013; 1: 40-47.
    • (2013) JACC Heart Fail , vol.1 , pp. 40-47
    • Patel, K.1    Fonarow, G.C.2    Kitzman, D.W.3    Aban, I.B.4    Love, T.E.5    Allman, R.M.6
  • 54
    • 0033514046 scopus 로고    scopus 로고
    • The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): A randomised trial
    • CIBIS-II Investigators
    • CIBIS-II Investigators. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): A randomised trial. Lancet 1999; 353: 9-13.
    • (1999) Lancet , vol.353 , pp. 9-13
  • 55
    • 42749091581 scopus 로고    scopus 로고
    • Beneficial effects of bisoprolol on the survival of hypertensive diastolic heart failure model rats
    • Nishio M, Sakata Y, Mano T, Ohtani T, Takeda Y, Miwa T, et al. Beneficial effects of bisoprolol on the survival of hypertensive diastolic heart failure model rats. Eur J Heart Fail 2008; 10: 446-453.
    • (2008) Eur J Heart Fail , vol.10 , pp. 446-453
    • Nishio, M.1    Sakata, Y.2    Mano, T.3    Ohtani, T.4    Takeda, Y.5    Miwa, T.6
  • 56
    • 11144296782 scopus 로고    scopus 로고
    • Beta-blocker improves survival, left ventricular function and myocardial remodeling in hypertensive rats with diastolic heart failure
    • Kobayashi M, Machida N, Mitsuishi M, Yamane Y. Beta-blocker improves survival, left ventricular function and myocardial remodeling in hypertensive rats with diastolic heart failure. Am J Hypertens 2004; 17: 1112-1119.
    • (2004) Am J Hypertens , vol.17 , pp. 1112-1119
    • Kobayashi, M.1    McHida, N.2    Mitsuishi, M.3    Yamane, Y.4
  • 57
    • 84871210322 scopus 로고    scopus 로고
    • Effects of carvedilol on heart failure with preserved ejection fraction: The Japanese Diastolic Heart Failure study (J-DHF)
    • Yamamoto K, Origasa H, Hori M. Effects of carvedilol on heart failure with preserved ejection fraction: The Japanese Diastolic Heart Failure study (J-DHF). Eur J Heart Fail 2013; 15: 110-118.
    • (2013) Eur J Heart Fail , vol.15 , pp. 110-118
    • Yamamoto, K.1    Origasa, H.2    Hori, M.3
  • 58
    • 84874425263 scopus 로고    scopus 로고
    • Increased passive stiffness of cardiomyocytes in the transverse direction and residual actin and myosin cross-bridge formation in hypertrophied rat hearts induced by chronic β-adrenergic stimulation
    • Sumita Yoshikawa W, Nakamura K, Miura D, Shimizu J, Hashimoto K, Kataoka N, et al. Increased passive stiffness of cardiomyocytes in the transverse direction and residual actin and myosin cross-bridge formation in hypertrophied rat hearts induced by chronic β-adrenergic stimulation. Circ J 2012; 77: 741-748.
    • (2012) Circ J , vol.77 , pp. 741-748
    • Sumita Yoshikawa, W.1    Nakamura, K.2    Miura, D.3    Shimizu, J.4    Hashimoto, K.5    Kataoka, N.6
  • 60
    • 59749101436 scopus 로고    scopus 로고
    • The failing diabetic heart: Focus on diastolic left ventricular dysfunction
    • van Heerebeek L, Somsen A, Paulus WJ. The failing diabetic heart: Focus on diastolic left ventricular dysfunction. Curr Diab Rep 2009; 9: 79-86.
    • (2009) Curr Diab Rep , vol.9 , pp. 79-86
    • van Heerebeek, L.1    Somsen, A.2    Paulus, W.J.3
  • 61
    • 77649254203 scopus 로고    scopus 로고
    • Passive stiffness of myocardium from congenital heart disease and implications for diastole
    • Chaturvedi RR, Herron T, Simmons R, Shore D, Kumar P, Sethia B, et al. Passive stiffness of myocardium from congenital heart disease and implications for diastole. Circulation 2010; 121: 979-988.
    • (2010) Circulation , vol.121 , pp. 979-988
    • Chaturvedi, R.R.1    Herron, T.2    Simmons, R.3    Shore, D.4    Kumar, P.5    Sethia, B.6
  • 62
    • 0035941407 scopus 로고    scopus 로고
    • The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system
    • Bang ML, Centner T, Fornoff F, Geach AJ, Gotthardt M, McNabb M, et al. The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system. Circ Res 2001; 89: 1065-1072.
    • (2001) Circ Res , vol.89 , pp. 1065-1072
    • Bang, M.L.1    Centner, T.2    Fornoff, F.3    Geach, A.J.4    Gotthardt, M.5    McNabb, M.6
  • 63
    • 15244348075 scopus 로고    scopus 로고
    • Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner
    • Fukuda N, Wu Y, Nair P, Granzier HL. Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner. J Gen Physiol 2005; 125: 257-271.
    • (2005) J Gen Physiol , vol.125 , pp. 257-271
    • Fukuda, N.1    Wu, Y.2    Nair, P.3    Granzier, H.L.4
  • 65
    • 3142672018 scopus 로고    scopus 로고
    • Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy
    • Nagueh SF, Shah G, Wu Y, Torre-Amione G, King NM, Lahmers S, et al. Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy. Circulation 2004; 110: 155-162.
    • (2004) Circulation , vol.110 , pp. 155-162
    • Nagueh, S.F.1    Shah, G.2    Wu, Y.3    Torre-Amione, G.4    King, N.M.5    Lahmers, S.6
  • 66
    • 4944235675 scopus 로고    scopus 로고
    • Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts
    • Makarenko I, Opitz CA, Leake MC, Neagoe C, Kulke M, Gwathmey JK, et al. Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts. Circ Res 2004; 95: 708-716.
    • (2004) Circ Res , vol.95 , pp. 708-716
    • Makarenko, I.1    Opitz, C.A.2    Leake, M.C.3    Neagoe, C.4    Kulke, M.5    Gwathmey, J.K.6
  • 67
    • 59649084739 scopus 로고    scopus 로고
    • Protein kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs
    • Kruger M, Kotter S, Grutzner A, Lang P, Andresen C, Redfield MM, et al. Protein kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs. Circ Res 2009; 104: 87-94.
    • (2009) Circ Res , vol.104 , pp. 87-94
    • Kruger, M.1    Kotter, S.2    Grutzner, A.3    Lang, P.4    Andresen, C.5    Redfield, M.M.6
  • 68
    • 84865529392 scopus 로고    scopus 로고
    • L-carnitine prevents the development of ventricular fibrosis and heart failure with preserved ejection fraction in hypertensive heart disease
    • Omori Y, Ohtani T, Sakata Y, Mano T, Takeda Y, Tamaki S, et al. L-carnitine prevents the development of ventricular fibrosis and heart failure with preserved ejection fraction in hypertensive heart disease. J Hypertens 2012; 30: 1834-1844.
    • (2012) J Hypertens , vol.30 , pp. 1834-1844
    • Omori, Y.1    Ohtani, T.2    Sakata, Y.3    Mano, T.4    Takeda, Y.5    Tamaki, S.6


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