Increased passive stiffness of cardiomyocytes in the transverse direction and residual actin and myosin cross-bridge formation in hypertrophied rat hearts induced by chronic β-adrenergic stimulation

Circulation Journal

Volumn 77, Issue 3, 2013, Pages 741-748

  Yoshikawa, Wakako Sumita ^a   Nakamura, Kazufumi ^a   Miura, Daiji ^a   Shimizu, Juichiro ^b   Hashimoto, Ken ^c   Kataoka, Noriyuki ^c   Toyota, Hiroko ^c   Okuyama, Hiroshi ^c   Miyoshi, Toru ^a   Morita, Hiroshi ^a   Kusano, Kengo Fukushima ^a   Matsuo, Tatsuhito ^e   Takaki, Miyako ^d   Kajiya, Fumihiko ^c   Yagi, Naoto ^a   Ohe, Tohru ^a   Ito, Hiroshi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b HIROSHIMA INTERNATIONAL UNIVERSITY   (Japan)

^c KAWASAKI MEDICAL SCHOOL   (Japan)

^d NARA MEDICAL UNIVERSITY   (Japan)

^e JAPAN SYNCHROTRON RADIATION RESEARCH INSTITUTE   (Japan)

Author keywords

Diastolic dysfunction; Heart failure; Myocytes; Stiffness

Indexed keywords

ACTIN; ISOPRENALINE; MYOSIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; BODY WEIGHT; CONTROLLED STUDY; ECHOCARDIOGRAPHY; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; HEART PAPILLARY MUSCLE; HEART WEIGHT; HISTOLOGY; MALE; MUSCLE RIGIDITY; NONHUMAN; RAT; TRANSTHORACIC ECHOCARDIOGRAPHY; X RAY DIFFRACTION; YOUNG MODULUS;

ACTINS; ADRENERGIC BETA-AGONISTS; ANIMALS; CARDIOMEGALY; CELLS, CULTURED; DIACETYL; DISEASE MODELS, ANIMAL; ELASTICITY; ENZYME INHIBITORS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HYPERTROPHY, LEFT VENTRICULAR; ISOPROTERENOL; MALE; MICROSCOPY, ATOMIC FORCE; MYOCYTES, CARDIAC; MYOSINS; ORGAN SIZE; PAPILLARY MUSCLES; RATS; RATS, WISTAR;

EID: 84874425263     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-12-0779     Document Type: Article

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