Association among Polymorphisms in EGFR Gene Exons, Lifestyle and Risk of Gastric Cancer with Gender Differences in Chinese Han Subjects

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Zhang, Junfeng ^a   Zhan, Zhen ^a   Wu, Juan ^a   Zhang, Chunbing ^b   Yang, Yaping ^a   Tong, Shujuan ^a   Sun, Zheng ^b   Qin, Lei ^a   Yang, Xuewen ^b   Dong, Wei ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b AFFILIATED HOSPITAL OF NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; SODIUM CHLORIDE;

ADULT; ALCOHOL CONSUMPTION; ALLELE; ARTICLE; CANCER INCIDENCE; CANCER RISK; CHINA; CHINESE; CONTROLLED STUDY; EGFR GENE; EXON; FEEDING BEHAVIOR; FEMALE; FOOD PREFERENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HIGH RISK POPULATION; HOSPITAL BASED CASE CONTROL STUDY; HUMAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; PREDICTION; SALT INTAKE; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; STOMACH CANCER;

ADENOCARCINOMA; AGED; ALCOHOL DRINKING; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; EXONS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LIFE STYLE; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, EPIDERMAL GROWTH FACTOR; RISK FACTORS; SMOKING; SODIUM CHLORIDE, DIETARY; STOMACH NEOPLASMS;

EID: 84875551505     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059254     Document Type: Article

References (57)

1. American Cancer Society (2011) Global Cancer Facts & Figures 2nd Edition. Atlanta: American Cancer Society: 19-20.
2. Yang L, (2006) Incidence and mortality of gastric cancer in China. World J Gastroenterol 1: 17-20.
3. Wöhrer SS, Raderer M, Hejna M, (2004) Palliative chemotherapy for advanced gastric cancer. Ann Oncol 11: 1585-95.
4. Sun X, Mu R, Zhou Y, Dai X, Qiao Y, et al. (2002) 1990-1992 mortality of stomach cancer in China. Zhonghua Zhong Liu Za Zhi 1: 4-8.
5. Jin GF, Miao RF, Deng YM, Hu ZB, Zhou Y, et al. (2007) Variant genotypes and haplotypes of the epidermal growth factor gene promoter are associated with a decreased risk of gastric cancer in a high-risk Chinese population. Cancer Sci 6: 864-868.
6. Forman D, Burley VJ, (2006) Gastric cancer: global pattern of the disease and an overview of environmental risk factors. Best Practice and Research Clinical Gastroenterology 4: 633-649.
7. Song HJ, Kim HJ, Choi NK, Hahn S, Cho YJ, et al. (2008) Gender differences in gastric cancer incidence in elderly former drinkers. Alcohol 42: 363-368.
8. Compare D, Rocco A, Nardone G, (2010) Risk factors in gastric cancer. Eur Rev Med Pharmacol Sci 14: 302-308.
9. Yasui W, Oue N, Aung PP, Matsumura S, Shutoh M, et al. (2005) Molecular-pathological prognostic factors of gastric cancer: a review. Gastric Cancer 2: 86-94.
10. Wang D, Zhou J, Wang T, Li X, Li S, et al. (2012) Polymorphisms in MSH2 gene and risk of gastric cancer, and interactions with lifestyle factors in a Chinese population. Cancer Epidemiol 36: 171-176.
11. Mammano E, Belluco C, Sciro M, Mencarelli R, Agostini M, et al. (2006) Epidermal growth factor receptor (EGFR): mutational and protein expression analysis in gastric cancer. Anticancer Res 26(5A): 3547-3550.
12. David L, Seruca R, Nesland JM, Soares P, Sansonetty F, et al. (1992) c-erbB-2 expression in primary gastric carcinomas and their metastases. Mod Pathol 4: 384-390.
13. Moutinho C, Mateus AR, Milanezi F, Carneiro F, Seruca R, et al. (2008) Epidermal growth factor receptor structural alterations in gastric cancer. BMC Cancer 8: 10.
14. Shen H, Xu Y, Qian Y, Yu R, Qin Y, et al. (2000) Polymorphisms of the DNA repair gene XRCC1 and risk of gastric cancer in a Chinese population. Int J Cancer 4: 601-606.
15. Shen H, Xu Y, Zheng Y, Qian Y, Yu R, et al. (2001) Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of gastric cancer in a Chinese population: a case-control study. Int J Cancer 5: 332-336.
16. Deng L, Huang R, Chen Z, Wu L, Xu DL, (2009) A study on polymorphisms of elastin gene in Chinese Han patients with isolated systolic hypertension. Am J Hypertens 6: 656-662.
17. Zhan Z, Wu J, Zhang JF, Yang YP, Tong S, et al. (2012) CDH1 gene polymorphisms, plasma CDH1 levels and risk of gastric cancer in a Chinese population. Mol Biol Rep 8: 8107-8113.
18. Qin L, Zhang JF, Yang YP, Li J, Tong SJ, et al. (2012) Association between CDH1 gene polymorphisms and tongue coatings in patients with gastric adenocarcinoma. World Chinese Journal of Digestology 14: 1191-1198.
19. Baulcombe D, (2002) DNA events: an RNA microcosm. Science 5589: 2002-2003.
20. Ji BT, Gao RN, Jin F, Yang G, Zheng W, et al. (1992) A population-based case-control study of dietary factors and stomach cancer risk in Shanghai urban areas. Tumor (Shanghai) 12: 201-205 (China).
21. Gao Y, Hua N, Han XY, Ding T, Giffen C, et al. (2011) Risk factors for esophageal and gastric cancers in Shanxi Province, China: A case-control study. Cancer Epidemiol 35: 91-99.
22. Cross AJ, Leitzmann MF, Gail MH, Hollenbeck AR, Schatzkin A, et al. (2007) A prospective study of red and processed meat intake in relation to cancer risk. PLoS Medicine 4: 1973-1984.
23. Zhou XB, Zhang J, Zhang CY, (2006) Meta analysis of association between life habits and stomach cancer in Chinese people. Zhongguo Linchuang Kangfu 48: 10-13 (China).
24. Ding JH, Li SP, Wu JZ, Cao HX, Gao CM, et al. (2008) Comparative study of gastric cancer risk factors between developed region and developing region in Jiangsu province. China Cancer 2: 88-90 (China).
25. Navarro Silvera SA, Mayne ST, Risch HA, Gammon MD, Vaughan T, et al. (2011) Principal component analysis of dietary and lifestyle patterns in relation to risk of subtypes of esophageal and gastric cancer. Ann Epidemiol 21: 543-550.
26. Laroiya I, Pankaja SS, Mittal S, Kate V, (2012) A study of Helicobacter pylori infection, dietary pattern and habits in patients with gastric cancer in South India. Asian Pac J Trop Dis 1: 24-26.
27. Eichholzer M, Gutzwiller F, (1998) Dietary nitrates, nitrites, and N-nitroso compounds and cancer risk: a review of the epidemiologic evidence. Nutr Rev 56: 95-105.
28. Tsugane S, Sasazuki S, (2007) Diet and the risk of gastric cancer: review of epidemiological evidence. Gastric Cancer 10: 75-83.
29. Wang HY, Ma L, Li Y, Cho CH, (2000) Exposure to cigarette smoking increase apoptosis in the rat gastric mucosa through a reactive oxygen species-mediated and P53-independent pathway. Free Radical Biology and Medicine 7: 1125-1131.
30. Bujanda L, (2000) The effects of alcohol consumption upon the gastrointestinal tract. The American Journal of Gastroenterology 12: 3374-3382.
31. Chang KW, Sarraj S, Lin SC, Tsai PI, Solt D, (2000) p53 expression, p53 and Ha-ras mutation and telomerase activation during nitrosamine-mediated hamster pouch carcinogenesis. Carcinogenesis 7: 1441-1451.
32. Bressac B, Puisieux A, Kew M, Volkmann M, Bozcall S, et al. (1991) p53 mutation in hepatocellular carcinoma after aflatoxin exposure. The Lancet 8779: 1356-1359.
33. Abate-Shen C, (2002) Deregulated homeobox gene expression in cancer: cause or consequence? Nat Rev Cancer 10: 777-785.
34. Yan JQ, Li F, Chen RY, Li SL, Zhao GQ, et al. (2010) Correlation between the EGFR gene single nucleotide polymorphisms and gastric cancer. Shandong Medical Journal 7: 18-20.
35. Sun JZ, Hu NY, Yi JP, Yang XX, Li X, et al. (2010) Relationship of EGFR gene rs763317 single nucleotide polymorphism with genetic susceptibility of gastric cancer. Chin J Cancer Prev Treat 10: 724-727.
36. Klapper LN, Kirchbaum MH, Sela M, Yarden Y, (2000) Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors. Adv Adv Cancer Res 77: 25-79.
37. Nicholson RI, Gee JM, Harper ME, (2001) EGFR and cancer prognosis. Eur J Cancer 4: 9-15.
38. Araujo A, Ribeiro R, Azevedo I, Coelho A, Soares M, et al. (2007) Genetic polymorphisms of the epidermal growth factor and related receptor in non-small cell lung cancer. Oncologist 2: 201-210.
39. Hsieh YY, Tzeng CH, Chen MH, Chen PM, Wang WS, (2012) Epidermal growth factor receptor R521K polymorphism shows favorable outcome to cetuximab-based treatment in KRAS wild-type colorectal cancer patients. Cancer Sci 4: 791-796.
40. Lo HW, Hsu SC, Hung MC, (2006) EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization. Breast Cancer Res Treat 3: 211-218.
41. Farnebo L, Jedlinski A, Ansell A, Vainikka L, Thunell LK, et al. (2009) Proteins and single nucleotide polymorphisms involved in apoptosis, growth control, and DNA repair predict cisplatin sensitivity in head and neck cancer cell lines. Int J Mol Med 4: 549-556.
42. Mellon K, Wright C, Kelly P, Horne CH, Neal DE, (1995) Long-term outcome related to epidermal growth factor receptor status in bladder cancer. J Urol 2: 919-925.
43. Tanner M, Hollmén M, Junttila TT, Kapanen AI, Tommola S, et al. (2005) Amplification of HER-2 in gastric carcinoma: association with Topoisomerase IIalpha gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab. Ann Oncol 2: 273-278.
44. Chintala L, Kurzrock R, (2010) Epidermal growth factor receptor mutation and diverse tumors: case report and concise literature review. Mol Oncol 4: 306-308.
45. Goto K, Ichinose Y, Ohe Y, Yamamoto N, Negoro S, et al. (2012) Epidermal growth factor receptor mutation status in circulating free DNA in serum: from IPASS, a phase III study of gefitinib or carboplatin/paclitaxel in non-small cell lung cancer. J Thorac Oncol 1: 115-121.
46. Kishida O, Miyazaki Y, Murayama Y, Ogasa M, Miyazaki T, et al. (2005) Gefitinib (Iressa, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells. Cancer Chemother Pharmacol 6: 584-594.
47. Wainberg ZA, Anghel A, Desai AJ, Ayala R, Luo T, et al. (2010) Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo. Clin Cancer Res 5: 1509-1519.
48. Han SW, Oh DY, Im SA, Park SR, Lee KW, et al. (2010) Epidermal growth factor receptor intron 1 CA dinucleotide repeat polymorphism and survival of advanced gastric cancer patients treated with cetuximab plus modified FOLFOX6. Cancer Sci 3: 793-799.
49. Puyo S, Le Morvan V, Robert J, (2008) Impact of EGFR gene polymorphisms on anticancer drug cytotoxicity in vitro. Mol Diagn Ther 4: 225-234.
50. Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, et al. (2004) EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 5676: 1497-1500.
51. Ma F, Xu B, Lin D, Sun T, Shi Y, (2011) Effect of rs2293347 Polymorphism in EGFR on the Clinical Efficacy of Gefitinib in Patients with Non-small Cell Lung Cancer. Zhongguo Fei Ai Za Zhi 8: 642-645.
52. Nie Q, Yang X, An S, Zhang XC, Yang JJ, et al. (2011) CYP1A1*2A polymorphism as a predictor of clinical outcome in advanced lung cancer patients treated with EGFR-TKI and its combined effects with EGFR intron 1 (CA)n polymorphism. Eur J Cancer 13: 1962-1970.
53. Krohn V, Wiegand S, Werner JA, Mandic R, (2011) EGFR codon 497 polymorphism- implications for receptor sensitivity to inhibitors in HNSCC cell lines. Anticancer Res 1: 59-65.
54. Kaneko K, Kumekawa Y, Makino R, Nozawa H, Hirayama Y, et al. (2010) EGFR gene alterations as a prognostic biomarker in advanced esophageal squamous cell carcinoma. Front Biosci 15: 65-72.
55. Liu Z, Liu L, Li M, Feng L, Zhang Q, et al. (2011) Epidermal growth factor receptor mutation in gastric cancer. Pathology 3: 234-238.
56. Sasaki H, Okuda K, Takada M, Kawahara M, Kitahara N, et al. (2008) A novel EGFR mutation D1012H and polymorphism at exon 25 in Japanese lung cancer. J Cancer Res Clin Oncol 12: 1371-1376.
57. Santoro R, Carboni F, Lepiane P, Ettorre GM, Santoro E, (2007) Clinicopathological features and prognosis of gastric cancer in young European adults. Br J Surg 94: 737-742.