Morphine Induces Albuminuria by Compromising Podocyte Integrity

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Lan, Xiqian ^a   Rai, Partab ^a   Chandel, Nirupama ^a   Cheng, Kang ^a   Lederman, Rivka ^a   Saleem, Moin A ^b   Mathieson, Peter W ^b   Husain, Mohammad ^a   Crosson, John T ^c   Gupta, Kalpna ^c   Malhotra, Ashwani ^a   Singhal, Pravin C ^a  

^a DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

^b SOUTHMEAD HOSPITAL   (United Kingdom)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CD2 ASSOCIATED PROTEIN; KAPPA OPIATE RECEPTOR; MORPHINE; MU OPIATE RECEPTOR; NEPHRIN; PODOCIN; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; SYNAPTOPODIN;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ELECTRON MICROSCOPY; ENZYME ACTIVATION; GLOMERULAR FILTRATION BARRIER; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROALBUMINURIA; NONHUMAN; OXIDATIVE STRESS; PODOCYTE; PROTEIN EXPRESSION; PROTEINURIA; SIGNAL TRANSDUCTION; SLIT DIAPHRAGM; URINALYSIS; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALBUMINURIA; ANIMALS; CELL LINE, TRANSFORMED; CYTOSKELETAL PROTEINS; GENE EXPRESSION REGULATION; GLOMERULAR FILTRATION RATE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE; MORPHINE; NARCOTICS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PODOCYTES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; RENAL INSUFFICIENCY, CHRONIC;

MUS;

EID: 84875545082     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055748     Document Type: Article

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