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Volumn 376, Issue 4, 2008, Pages 706-711

Activated macrophages down-regulate podocyte nephrin and podocin expression via stress-activated protein kinases

Author keywords

Cytoskeleton; IFN ; JNK; NF B; p38 MAPK; TNF

Indexed keywords

MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NEPHRIN; PODOCIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 53449093804     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.09.049     Document Type: Article
Times cited : (48)

References (33)
  • 1
    • 34250006557 scopus 로고    scopus 로고
    • The spectrum of podocytopathies: a unifying view of glomerular diseases
    • Wiggins R.C. The spectrum of podocytopathies: a unifying view of glomerular diseases. Kidney Int. 71 (2007) 1205-1214
    • (2007) Kidney Int. , vol.71 , pp. 1205-1214
    • Wiggins, R.C.1
  • 2
    • 0032015551 scopus 로고    scopus 로고
    • Positionally cloned gene for a novel glomerular protein-nephrin is mutated in congenital nephrotic syndrome
    • Kestila M., Lenkkeri U., Mannikko M., Lamerdin J., McCready P., Putaala H., et al. Positionally cloned gene for a novel glomerular protein-nephrin is mutated in congenital nephrotic syndrome. Mol. Cell 1 (1998) 575-582
    • (1998) Mol. Cell , vol.1 , pp. 575-582
    • Kestila, M.1    Lenkkeri, U.2    Mannikko, M.3    Lamerdin, J.4    McCready, P.5    Putaala, H.6
  • 3
    • 0034034757 scopus 로고    scopus 로고
    • NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome
    • Boute N., Gribouval O., Roselli S., Benessy F., Lee H., Fuchshuber A., et al. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. Nat. Genet. 24 (2000) 349-354
    • (2000) Nat. Genet. , vol.24 , pp. 349-354
    • Boute, N.1    Gribouval, O.2    Roselli, S.3    Benessy, F.4    Lee, H.5    Fuchshuber, A.6
  • 4
    • 0001689625 scopus 로고    scopus 로고
    • Macrophages in immune renal injury
    • Neilson E.G., and Couser W.G. (Eds), Lippincott, Williams & Wilkins, Philadelphia
    • Nikolic-Paterson D.J. Macrophages in immune renal injury. In: Neilson E.G., and Couser W.G. (Eds). Immunologic Renal Disease (2001), Lippincott, Williams & Wilkins, Philadelphia 609-632
    • (2001) Immunologic Renal Disease , pp. 609-632
    • Nikolic-Paterson, D.J.1
  • 5
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat. Rev. Immunol. 3 (2003) 23-35
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 23-35
    • Gordon, S.1
  • 7
    • 4344645768 scopus 로고    scopus 로고
    • The role of lymphocytes in the experimental progressive glomerulonephritis
    • Ikezumi Y., Kanno K., Karasawa T., Han G.D., Ito Y., Koike H., et al. The role of lymphocytes in the experimental progressive glomerulonephritis. Kidney Int. 66 (2004) 1036-1048
    • (2004) Kidney Int. , vol.66 , pp. 1036-1048
    • Ikezumi, Y.1    Kanno, K.2    Karasawa, T.3    Han, G.D.4    Ito, Y.5    Koike, H.6
  • 8
    • 0037213079 scopus 로고    scopus 로고
    • Adoptive transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation
    • Ikezumi Y., Hurst L.A., Masaki T., Atkins R.C., and Nikolic-Paterson D.J. Adoptive transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation. Kidney Int. 63 (2003) 83-95
    • (2003) Kidney Int. , vol.63 , pp. 83-95
    • Ikezumi, Y.1    Hurst, L.A.2    Masaki, T.3    Atkins, R.C.4    Nikolic-Paterson, D.J.5
  • 9
    • 0037378759 scopus 로고    scopus 로고
    • Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoid-sensitive mechanism
    • Ikezumi Y., Atkins R.C., and Nikolic-Paterson D.J. Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoid-sensitive mechanism. J. Am. Soc. Nephrol. 14 (2003) 888-898
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 888-898
    • Ikezumi, Y.1    Atkins, R.C.2    Nikolic-Paterson, D.J.3
  • 10
    • 0034022292 scopus 로고    scopus 로고
    • Cloning of rat nephrin: expression in developing glomeruli and in proteinuric states
    • Kawachi H., Koike H., Kurihara H., Yaoita E., Orikasa M., Shia M.A., et al. Cloning of rat nephrin: expression in developing glomeruli and in proteinuric states. Kidney Int. 57 (2000) 1949-1961
    • (2000) Kidney Int. , vol.57 , pp. 1949-1961
    • Kawachi, H.1    Koike, H.2    Kurihara, H.3    Yaoita, E.4    Orikasa, M.5    Shia, M.A.6
  • 11
    • 0037221437 scopus 로고    scopus 로고
    • Cloning of rat homologue of podocin: expression in proteinuric states and in developing glomeruli
    • Kawachi H., Koike H., Kurihara H., Sakai T., and Shimizu F. Cloning of rat homologue of podocin: expression in proteinuric states and in developing glomeruli. J. Am. Soc. Nephrol. 14 (2003) 46-56
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 46-56
    • Kawachi, H.1    Koike, H.2    Kurihara, H.3    Sakai, T.4    Shimizu, F.5
  • 12
    • 0031563832 scopus 로고    scopus 로고
    • Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines
    • Mundel P., Reiser J., Zuniga Mejia Borja A., Pavenstadt H., Davidson G.R., Kriz W., et al. Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines. Exp. Cell Res. 236 (1997) 248-258
    • (1997) Exp. Cell Res. , vol.236 , pp. 248-258
    • Mundel, P.1    Reiser, J.2    Zuniga Mejia Borja, A.3    Pavenstadt, H.4    Davidson, G.R.5    Kriz, W.6
  • 13
    • 0033935786 scopus 로고    scopus 로고
    • An anti-CD5 monoclonal antibody ameliorates proteinuria and glomerular lesions in rat mesangioproliferative glomerulonephritis
    • Ikezumi Y., Kawachi H., Toyabe S., Uchiyama M., and Shimizu F. An anti-CD5 monoclonal antibody ameliorates proteinuria and glomerular lesions in rat mesangioproliferative glomerulonephritis. Kidney Int. 58 (2000) 100-114
    • (2000) Kidney Int. , vol.58 , pp. 100-114
    • Ikezumi, Y.1    Kawachi, H.2    Toyabe, S.3    Uchiyama, M.4    Shimizu, F.5
  • 14
    • 0036229528 scopus 로고    scopus 로고
    • FK506 ameliorates proteinuria and glomerular lesions induced by anti-Thy 1.1 monoclonal antibody 1-22-3
    • Ikezumi Y., Kanno K., Koike H., Tomita M., Uchiyama M., Shimizu F., et al. FK506 ameliorates proteinuria and glomerular lesions induced by anti-Thy 1.1 monoclonal antibody 1-22-3. Kidney Int. 61 (2002) 1339-1350
    • (2002) Kidney Int. , vol.61 , pp. 1339-1350
    • Ikezumi, Y.1    Kanno, K.2    Koike, H.3    Tomita, M.4    Uchiyama, M.5    Shimizu, F.6
  • 15
    • 0030967360 scopus 로고    scopus 로고
    • TNF-α up-regulates renal MIF expression in rat crescentic glomerulonephritis
    • Lan H.Y., Yang N., Metz C., Mu W., Song Q., Nikolic-Paterson D.J., et al. TNF-α up-regulates renal MIF expression in rat crescentic glomerulonephritis. Mol. Med. 3 (1997) 136-144
    • (1997) Mol. Med. , vol.3 , pp. 136-144
    • Lan, H.Y.1    Yang, N.2    Metz, C.3    Mu, W.4    Song, Q.5    Nikolic-Paterson, D.J.6
  • 16
    • 17744382183 scopus 로고    scopus 로고
    • Antibody blockade of TNF-α reduces inflammation and scarring in experimental crescentic glomerulonephritis
    • Khan S.B., Cook H.T., Bhangal G., Smith J., Tam F.W., and Pusey C.D. Antibody blockade of TNF-α reduces inflammation and scarring in experimental crescentic glomerulonephritis. Kidney Int. 67 (2005) 1812-1820
    • (2005) Kidney Int. , vol.67 , pp. 1812-1820
    • Khan, S.B.1    Cook, H.T.2    Bhangal, G.3    Smith, J.4    Tam, F.W.5    Pusey, C.D.6
  • 17
    • 0027532596 scopus 로고
    • In situ production of TNF-α, IL-1-β and IL-2R in ANCA-positive glomerulonephritis
    • Noronha I.L., Kruger C., Andrassy K., Ritz E., and Waldherr R. In situ production of TNF-α, IL-1-β and IL-2R in ANCA-positive glomerulonephritis. Kidney Int. 43 (1993) 682-692
    • (1993) Kidney Int. , vol.43 , pp. 682-692
    • Noronha, I.L.1    Kruger, C.2    Andrassy, K.3    Ritz, E.4    Waldherr, R.5
  • 18
    • 0028988993 scopus 로고
    • Tumor necrosis factor-alpha is expressed by glomerular visceral epithelial cells in human membranous nephropathy
    • Neale T.J., Ruger B.M., Macaulay H., Dunbar P.R., Hasan Q., Bourke A., et al. Tumor necrosis factor-alpha is expressed by glomerular visceral epithelial cells in human membranous nephropathy. Am. J. Pathol. 146 (1995) 1444-1454
    • (1995) Am. J. Pathol. , vol.146 , pp. 1444-1454
    • Neale, T.J.1    Ruger, B.M.2    Macaulay, H.3    Dunbar, P.R.4    Hasan, Q.5    Bourke, A.6
  • 19
    • 18244402878 scopus 로고    scopus 로고
    • Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis
    • Vielhauer V., Stavrakis G., and Mayadas T.N. Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis. J. Clin. Invest. 115 (2005) 1199-1209
    • (2005) J. Clin. Invest. , vol.115 , pp. 1199-1209
    • Vielhauer, V.1    Stavrakis, G.2    Mayadas, T.N.3
  • 21
    • 3042628478 scopus 로고    scopus 로고
    • Macrophage-mediated renal injury is dependent on signaling via the JNK pathway
    • Ikezumi Y., Hurst L., Atkins R.C., and Nikolic-Paterson D.J. Macrophage-mediated renal injury is dependent on signaling via the JNK pathway. J. Am. Soc. Nephrol. 15 (2004) 1775-1784
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 1775-1784
    • Ikezumi, Y.1    Hurst, L.2    Atkins, R.C.3    Nikolic-Paterson, D.J.4
  • 22
    • 0942298030 scopus 로고    scopus 로고
    • P38 Mitogen-activated protein kinase activation and cell localization in human glomerulonephritis: correlation with renal injury
    • Stambe C., Nikolic-Paterson D.J., Hill P.A., Dowling J., and Atkins R.C. P38 Mitogen-activated protein kinase activation and cell localization in human glomerulonephritis: correlation with renal injury. J. Am. Soc. Nephrol. 15 (2004) 326-336
    • (2004) J. Am. Soc. Nephrol. , vol.15 , pp. 326-336
    • Stambe, C.1    Nikolic-Paterson, D.J.2    Hill, P.A.3    Dowling, J.4    Atkins, R.C.5
  • 23
    • 0037307476 scopus 로고    scopus 로고
    • Blockade of p38α MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis
    • Stambe C., Atkins R.C., Tesch G.H., Kapoun A.M., Hill P.A., Schreiner G.F., et al. Blockade of p38α MAPK ameliorates acute inflammatory renal injury in rat anti-GBM glomerulonephritis. J. Am. Soc. Nephrol. 14 (2003) 338-351
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 338-351
    • Stambe, C.1    Atkins, R.C.2    Tesch, G.H.3    Kapoun, A.M.4    Hill, P.A.5    Schreiner, G.F.6
  • 24
    • 0037218943 scopus 로고    scopus 로고
    • P38 Mitogen-activated protein kinase contributes to autoimmune renal injury in MRL-Fas lpr mice
    • Iwata Y., Wada T., Furuichi K., Sakai N., Matsushima K., Yokoyama H., et al. P38 Mitogen-activated protein kinase contributes to autoimmune renal injury in MRL-Fas lpr mice. J. Am. Soc. Nephrol. 14 (2003) 57-67
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 57-67
    • Iwata, Y.1    Wada, T.2    Furuichi, K.3    Sakai, N.4    Matsushima, K.5    Yokoyama, H.6
  • 25
    • 34047205066 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis and suppresses monocyte chemoattractant protein-1 but not IL-1β or IL-6
    • Sheryanna A., Bhangal G., McDaid J., Smith J., Manning A., Foxwell B.M., et al. Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis and suppresses monocyte chemoattractant protein-1 but not IL-1β or IL-6. J. Am. Soc. Nephrol. 18 (2007) 1167-1179
    • (2007) J. Am. Soc. Nephrol. , vol.18 , pp. 1167-1179
    • Sheryanna, A.1    Bhangal, G.2    McDaid, J.3    Smith, J.4    Manning, A.5    Foxwell, B.M.6
  • 26
    • 30344475768 scopus 로고    scopus 로고
    • Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome
    • Koshikawa M., Mukoyama M., Mori K., Suganami T., Sawai K., Yoshioka T., et al. Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome. J. Am. Soc. Nephrol. 16 (2005) 2690-2701
    • (2005) J. Am. Soc. Nephrol. , vol.16 , pp. 2690-2701
    • Koshikawa, M.1    Mukoyama, M.2    Mori, K.3    Suganami, T.4    Sawai, K.5    Yoshioka, T.6
  • 27
    • 42549105123 scopus 로고    scopus 로고
    • Podocyte injury induced by albumin overload in vivo and in vitro: involvement of TGF-β and p38 MAPK
    • Yoshida S., Nagase M., Shibata S., and Fujita T. Podocyte injury induced by albumin overload in vivo and in vitro: involvement of TGF-β and p38 MAPK. Nephron Exp. Nephrol. 108 (2008) e57-e68
    • (2008) Nephron Exp. Nephrol. , vol.108
    • Yoshida, S.1    Nagase, M.2    Shibata, S.3    Fujita, T.4
  • 28
    • 34548485289 scopus 로고    scopus 로고
    • A pathogenic role for JNK signaling in experimental anti-GBM glomerulonephritis
    • Flanc R.S., Ma F.Y., Tesch G.H., Han Y., Atkins R.C., Bennett B.L., et al. A pathogenic role for JNK signaling in experimental anti-GBM glomerulonephritis. Kidney Int. 72 (2007) 698-708
    • (2007) Kidney Int. , vol.72 , pp. 698-708
    • Flanc, R.S.1    Ma, F.Y.2    Tesch, G.H.3    Han, Y.4    Atkins, R.C.5    Bennett, B.L.6
  • 29
    • 53449092851 scopus 로고    scopus 로고
    • F.Y. Ma, J. Liu, D.J. Nikolic-Paterson, The role of stress-activated protein kinase signaling in renal pathophysiology. Braz. J. Med. Biol. Res., in press.
    • F.Y. Ma, J. Liu, D.J. Nikolic-Paterson, The role of stress-activated protein kinase signaling in renal pathophysiology. Braz. J. Med. Biol. Res., in press.
  • 30
    • 0036721605 scopus 로고    scopus 로고
    • Complement activates the c-Jun N-terminal kinase/stress-activated protein kinase in glomerular epithelial cells
    • Peng H., Takano T., Papillon J., Bijian K., Khadir A., and Cybulsky A.V. Complement activates the c-Jun N-terminal kinase/stress-activated protein kinase in glomerular epithelial cells. J. Immunol. 169 (2002) 2594-2601
    • (2002) J. Immunol. , vol.169 , pp. 2594-2601
    • Peng, H.1    Takano, T.2    Papillon, J.3    Bijian, K.4    Khadir, A.5    Cybulsky, A.V.6
  • 31
    • 0038407518 scopus 로고    scopus 로고
    • Inflammatory cytokines upregulate nephrin expression in human embryonic kidney epithelial cells and podocytes
    • Huwiler A., Ren S., Holthofer H., Pavenstadt H., and Pfeilschifter J. Inflammatory cytokines upregulate nephrin expression in human embryonic kidney epithelial cells and podocytes. Biochem. Biophys. Res. Commun. 305 (2003) 136-142
    • (2003) Biochem. Biophys. Res. Commun. , vol.305 , pp. 136-142
    • Huwiler, A.1    Ren, S.2    Holthofer, H.3    Pavenstadt, H.4    Pfeilschifter, J.5
  • 32
    • 33846429631 scopus 로고    scopus 로고
    • Transcriptional suppression of nephrin in podocytes by macrophages: roles of inflammatory cytokines and involvement of the PI3K/Akt pathway
    • Takano Y., Yamauchi K., Hayakawa K., Hiramatsu N., Kasai A., Okamura M., et al. Transcriptional suppression of nephrin in podocytes by macrophages: roles of inflammatory cytokines and involvement of the PI3K/Akt pathway. FEBS Lett. 581 (2007) 421-426
    • (2007) FEBS Lett. , vol.581 , pp. 421-426
    • Takano, Y.1    Yamauchi, K.2    Hayakawa, K.3    Hiramatsu, N.4    Kasai, A.5    Okamura, M.6
  • 33
    • 0032782860 scopus 로고    scopus 로고
    • TNF-α induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase
    • Koukouritaki S.B., Vardaki E.A., Papakonstanti E.A., Lianos E., Stournaras C., and Emmanouel D.S. TNF-α induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase. Mol. Med. 5 (1999) 382-392
    • (1999) Mol. Med. , vol.5 , pp. 382-392
    • Koukouritaki, S.B.1    Vardaki, E.A.2    Papakonstanti, E.A.3    Lianos, E.4    Stournaras, C.5    Emmanouel, D.S.6


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