Extracellular vesicles, especially derived from Gram-negative bacteria, in indoor dust induce neutrophilic pulmonary inflammation associated with both Th1 and Th17 cell responses

Clinical and Experimental Allergy

Volumn 43, Issue 4, 2013, Pages 443-454

  Kim, Y S ^a   Choi, E J ^a   Lee, W H ^a   Choi, S J ^a   Roh, T Y ^a   Park, J ^a   Jee, Y K ^b   Zhu, Z ^c   Koh, Y Y ^d   Gho, Y S ^a   Kim, Y K ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Dankook University College of Medicine   (South Korea)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Seoul National University College of Medicine   (South Korea)

Author keywords

Asthma; Extracellular vesicles; IFN gamma; IL 17; Neutrophilic inflammation

Indexed keywords

B7 ANTIGEN; CD11B ANTIGEN; CD14 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 12P70; INTERLEUKIN 6; POLYMYXIN B; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTHMA; ATOPY; BED; CELL VACUOLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATITIS; DUST; EXTRACELLULAR VESICLE; GRAM NEGATIVE BACTERIUM; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; INDOOR DUST; INNATE IMMUNITY; INTERNALIZATION; LUNG ALVEOLUS MACROPHAGE; LUNG INFILTRATE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PNEUMONIA; PRESCHOOL CHILD; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RHINITIS; SCHOOL CHILD; TH1 CELL; TH17 CELL; ULTRACENTRIFUGATION; ULTRAFILTRATION;

ADAPTIVE IMMUNITY; ANIMALS; ANTIGENS, CD14; CELL LINE; CELL-DERIVED MICROPARTICLES; CHILD; DUST; GRAM-NEGATIVE BACTERIA; HUMANS; IMMUNITY, INNATE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGES; MICE; NEUTROPHILS; PNEUMONIA; TH1 CELLS; TH17 CELLS;

EID: 84875544510     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/cea.12085     Document Type: Article

References (32)

1. Kim YK, Oh SY, Jeon SG et al. Airway exposure levels of lipopolysaccharide determine type 1 versus type 2 experimental asthma. J Immunol 2007; 178:5375-82.
2. Jeon SG, Oh SY, Park HK et al. TH2 and TH1 lung inflammation induced by airway allergen sensitization with low and high doses of double-stranded RNA. J Allergy Clin Immunol 2007; 120:803-12.
3. Busse WW, Lemanske RF Jr. Asthma. N Engl J Med 2001; 344:350-62.
4. Bateman ED, Hurd SS, Barnes PJ et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008; 31:143-78.
5. Haldar P, Pavord ID, Shaw DE et al. Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med 2008; 178:218-24.
6. Moore WC, Meyers DA, Wenzel SE et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 2010; 181:315-23.
7. Choi JP, Kim YS, Tae YM et al. A viral PAMP double-stranded RNA induces allergen-specific Th17 cell response in the airways which is dependent on VEGF and IL-6. Allergy 2010; 65:1322-30.
8. Cosmi L, Liotta F, Maggi E, Romagnani S, Annunziato F. Th17 cells: new players in asthma pathogenesis. Allergy 2011; 66:989-98.
9. Lee EY, Bang JY, Park GW et al. Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli. Proteomics 2007; 7:3143-53.
10. Lee EY, Choi DY, Kim DK et al. Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles. Proteomics 2009; 9:5425-36.
11. Park KS, Choi KH, Kim YS et al. Outer membrane vesicles derived from Escherichia coli induce systemic inflammatory response syndrome. PLoS ONE 2010; 5:e11334.
12. Hong SW, Kim MR, Lee EY et al. Extracellular vesicles derived from Staphylococcus aureus induce atopic dermatitis-like skin inflammation. Allergy 2011; 66:351-9.
13. Kim MR, Hong SW, Choi EB et al. Staphylococcus aureus-derived extracellular vesicles induce neutrophilic pulmonary inflammation via both Th1 and Th17 cell responses. Allergy 2012; 67:1271-81.
14. Kunding AH, Mortensen MW, Christensen SM, Stamou D. A fluorescence-based technique to construct size distributions from single-object measurements: application to the extrusion of lipid vesicles. Biophys J 2008; 95:1176-88.
15. Lee CH, Tsai CM. Quantification of bacterial lipopolysaccharides by the purpald assay: measuring formaldehyde generated from 2-keto-3-deoxyoctonate and heptose at the inner core by periodate oxidation. Anal Biochem 1999; 267:161-8.
16. Mikheyskaya LV, Ovodova RG, Ovodov YS. Isolation and characterization of lipopolysaccharides from cell walls of blue-green algae of the genus Phormidium. J Bacteriol 1977; 130:1-3.
17. Kim YS, Hong SW, Choi JP et al. Vascular endothelial growth factor is a key mediator in the development of T cell priming and its polarization to type 1 and type 17 T helper cells in the airways. J Immunol 2009; 183:5113-20.
18. Vives-Pi M, Somoza N, Fernandez-Alvarez J et al. Evidence of expression of endotoxin receptors CD14, toll-like receptors TLR4 and TLR2 and associated molecule MD-2 and of sensitivity to endotoxin (LPS) in islet beta cells. Clin Exp Immunol 2003; 133:208-18.
19. Triantafilou M, Triantafilou K. Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Trends Immunol 2002; 23:301-4.
20. Wu S, Rhee KJ, Albesiano E et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 2009; 15:1016-22.
21. Seltzer JM. Biological contaminants. J Allergy Clin Immunol 1994; 94:318-26.
22. Husman T. Health effects of indoor-air microorganisms. Scand J Work Environ Health 1996; 22:5-13.
23. Camara AA, Silva JM, Ferriani VP et al. Risk factors for wheezing in a subtropical environment: role of respiratory viruses and allergen sensitization. J Allergy Clin Immunol 2004; 113:551-7.
24. Michel O, Ginanni R, Duchateau J, Vertongen F, Le Bon B, Sergysels R. Domestic endotoxin exposure and clinical severity of asthma. Clin Exp Allergy 1991; 21:441-8.
25. Gereda JE, Leung DY, Thatayatikom A et al. Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma. Lancet 2000; 355:1680-3.
26. Mashburn-Warren LM, Whiteley M. Special delivery: vesicle trafficking in prokaryotes. Mol Microbiol 2006; 61:839-46.
27. Lee EY, Choi DS, Kim KP, Gho YS. Proteomics in gram-negative bacterial outer membrane vesicles. Mass Spectrom Rev 2008; 27:535-55.
28. Moon HG, Tae YM, Kim YS et al. Conversion of Th17-type into Th2-type inflammation by acetyl salicylic acid via the adenosine and uric acid pathway in the lung. Allergy 2010; 65:1093-103.
29. Braun-Fahrlander C, Riedler J, Herz U et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002; 347:869-77.
30. Thorne PS, Kulhankova K, Yin M, Cohn R, Arbes SJ Jr, Zeldin DC. Endotoxin exposure is a risk factor for asthma: the national survey of endotoxin in United States housing. Am J Respir Crit Care Med 2005; 172:1371-7.
31. Beutler B. Tlr4: central component of the sole mammalian LPS sensor. Curr Opin Immunol 2000; 12:20-6.
32. Holt PG. Key factors in the development of asthma: atopy. Am J Respir Crit Care Med 2000; 161:S172-5.