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Volumn 8, Issue 3, 2013, Pages

Silencing of RASSF3 by DNA Hypermethylation Is Associated with Tumorigenesis in Somatotroph Adenomas

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CELL PROTEIN; DNA; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; PROTEIN RASSF3; UNCLASSIFIED DRUG;

EID: 84875544282     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059024     Document Type: Article
Times cited : (20)

References (32)
  • 1
    • 66149120642 scopus 로고    scopus 로고
    • The pathogenesis of pituitary tumors
    • Asa SL, Ezzat S, (2009) The pathogenesis of pituitary tumors. Annu Rev Pathol 4: 97-126.
    • (2009) Annu Rev Pathol , vol.4 , pp. 97-126
    • Asa, S.L.1    Ezzat, S.2
  • 2
    • 0032246451 scopus 로고    scopus 로고
    • The cytogenesis and pathogenesis of pituitary adenomas
    • Asa SL, Ezzat S, (1998) The cytogenesis and pathogenesis of pituitary adenomas. Endocr Rev 19: 798-827.
    • (1998) Endocr Rev , vol.19 , pp. 798-827
    • Asa, S.L.1    Ezzat, S.2
  • 3
    • 80053159541 scopus 로고    scopus 로고
    • Identification of growth arrest and DNA-damage-inducible gene beta (GADD45beta) as a novel tumor suppressor in pituitary gonadotrope tumors
    • Michaelis KA, Knox AJ, Xu M, Kiseljak-Vassiliades K, Edwards MG, et al. (2011) Identification of growth arrest and DNA-damage-inducible gene beta (GADD45beta) as a novel tumor suppressor in pituitary gonadotrope tumors. Endocrinology 152: 3603-3613.
    • (2011) Endocrinology , vol.152 , pp. 3603-3613
    • Michaelis, K.A.1    Knox, A.J.2    Xu, M.3    Kiseljak-Vassiliades, K.4    Edwards, M.G.5
  • 4
    • 0036831826 scopus 로고    scopus 로고
    • The pathogenesis of pituitary tumours
    • Asa SL, Ezzat S, (2002) The pathogenesis of pituitary tumours. Nat Rev Cancer 2: 836-849.
    • (2002) Nat Rev Cancer , vol.2 , pp. 836-849
    • Asa, S.L.1    Ezzat, S.2
  • 5
    • 79955093923 scopus 로고    scopus 로고
    • Pathogenesis of pituitary tumors
    • Melmed S, (2011) Pathogenesis of pituitary tumors. Nat Rev Endocrinol 7: 257-266.
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 257-266
    • Melmed, S.1
  • 7
    • 0035184605 scopus 로고    scopus 로고
    • Genesis of pituitary adenomas: state of the art
    • Faglia G, Spada A, (2001) Genesis of pituitary adenomas: state of the art. J Neurooncol 54: 95-110.
    • (2001) J Neurooncol , vol.54 , pp. 95-110
    • Faglia, G.1    Spada, A.2
  • 8
    • 0027537296 scopus 로고
    • CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene
    • Ohtani-Fujita N, Fujita T, Aoike A, Osifchin NE, Robbins PD, et al. (1993) CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. Oncogene 8: 1063-1067.
    • (1993) Oncogene , vol.8 , pp. 1063-1067
    • Ohtani-Fujita, N.1    Fujita, T.2    Aoike, A.3    Osifchin, N.E.4    Robbins, P.D.5
  • 9
    • 79953062931 scopus 로고    scopus 로고
    • Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma
    • Morris MR, Ricketts CJ, Gentle D, McRonald F, Carli N, et al. (2011) Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma. Oncogene 30: 1390-1401.
    • (2011) Oncogene , vol.30 , pp. 1390-1401
    • Morris, M.R.1    Ricketts, C.J.2    Gentle, D.3    McRonald, F.4    Carli, N.5
  • 10
    • 0034161905 scopus 로고    scopus 로고
    • Loss of pRb expression in pituitary adenomas is associated with methylation of the RB1 CpG island
    • Simpson DJ, Hibberts NA, McNicol AM, Clayton RN, Farrell WE, (2000) Loss of pRb expression in pituitary adenomas is associated with methylation of the RB1 CpG island. Cancer Res 60: 1211-1216.
    • (2000) Cancer Res , vol.60 , pp. 1211-1216
    • Simpson, D.J.1    Hibberts, N.A.2    McNicol, A.M.3    Clayton, R.N.4    Farrell, W.E.5
  • 11
    • 34250809655 scopus 로고    scopus 로고
    • Epigenetic silencing through DNA and histone methylation of fibroblast growth factor receptor 2 in neoplastic pituitary cells
    • Zhu X, Lee K, Asa SL, Ezzat S, (2007) Epigenetic silencing through DNA and histone methylation of fibroblast growth factor receptor 2 in neoplastic pituitary cells. Am J Pathol 170: 1618-1628.
    • (2007) Am J Pathol , vol.170 , pp. 1618-1628
    • Zhu, X.1    Lee, K.2    Asa, S.L.3    Ezzat, S.4
  • 12
    • 34249989097 scopus 로고    scopus 로고
    • DNA methylation and histone modification regulate silencing of epithelial cell adhesion molecule for tumor invasion and progression
    • Tai KY, Shiah SG, Shieh YS, Kao YR, Chi CY, et al. (2007) DNA methylation and histone modification regulate silencing of epithelial cell adhesion molecule for tumor invasion and progression. Oncogene 26: 3989-3997.
    • (2007) Oncogene , vol.26 , pp. 3989-3997
    • Tai, K.Y.1    Shiah, S.G.2    Shieh, Y.S.3    Kao, Y.R.4    Chi, C.Y.5
  • 13
    • 17144371472 scopus 로고    scopus 로고
    • Inactivation of RASSF1A tumor suppressor gene by aberrant promoter hypermethylation in human pituitary adenomas
    • Qian ZR, Sano T, Yoshimoto K, Yamada S, Ishizuka A, et al. (2005) Inactivation of RASSF1A tumor suppressor gene by aberrant promoter hypermethylation in human pituitary adenomas. Lab Invest 85: 464-473.
    • (2005) Lab Invest , vol.85 , pp. 464-473
    • Qian, Z.R.1    Sano, T.2    Yoshimoto, K.3    Yamada, S.4    Ishizuka, A.5
  • 14
    • 36249025719 scopus 로고    scopus 로고
    • Tumor-specific downregulation and methylation of the CDH13 (H-cadherin) and CDH1 (E-cadherin) genes correlate with aggressiveness of human pituitary adenomas
    • Qian ZR, Sano T, Yoshimoto K, Asa SL, Yamada S, et al. (2007) Tumor-specific downregulation and methylation of the CDH13 (H-cadherin) and CDH1 (E-cadherin) genes correlate with aggressiveness of human pituitary adenomas. Mod Pathol 20: 1269-1277.
    • (2007) Mod Pathol , vol.20 , pp. 1269-1277
    • Qian, Z.R.1    Sano, T.2    Yoshimoto, K.3    Asa, S.L.4    Yamada, S.5
  • 16
    • 83255166586 scopus 로고    scopus 로고
    • Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines
    • da Costa Prando E, Cavalli LR, Rainho CA, (2011) Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines. Epigenetics 6: 1413-1424.
    • (2011) Epigenetics , vol.6 , pp. 1413-1424
    • da Costa Prando, E.1    Cavalli, L.R.2    Rainho, C.A.3
  • 17
    • 1842536844 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas
    • Hesson L, Bieche I, Krex D, Criniere E, Hoang-Xuan K, et al. (2004) Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas. Oncogene 23: 2408-2419.
    • (2004) Oncogene , vol.23 , pp. 2408-2419
    • Hesson, L.1    Bieche, I.2    Krex, D.3    Criniere, E.4    Hoang-Xuan, K.5
  • 18
    • 33749024160 scopus 로고    scopus 로고
    • Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer
    • Hoque MO, Feng Q, Toure P, Dem A, Critchlow CW, et al. (2006) Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer. J Clin Oncol 24: 4262-4269.
    • (2006) J Clin Oncol , vol.24 , pp. 4262-4269
    • Hoque, M.O.1    Feng, Q.2    Toure, P.3    Dem, A.4    Critchlow, C.W.5
  • 19
    • 77954615960 scopus 로고    scopus 로고
    • Methylation level of the RASSF1A promoter is an independent prognostic factor for clear-cell renal cell carcinoma
    • Kawai Y, Sakano S, Suehiro Y, Okada T, Korenaga Y, et al. (2010) Methylation level of the RASSF1A promoter is an independent prognostic factor for clear-cell renal cell carcinoma. Ann Oncol 21: 1612-1617.
    • (2010) Ann Oncol , vol.21 , pp. 1612-1617
    • Kawai, Y.1    Sakano, S.2    Suehiro, Y.3    Okada, T.4    Korenaga, Y.5
  • 20
    • 79960847694 scopus 로고    scopus 로고
    • High RASSF1A promoter methylation levels are predictive of poor prognosis in fine-needle aspirate washings of breast cancer lesions
    • Martins AT, Monteiro P, Ramalho-Carvalho J, Costa VL, Dinis-Ribeiro M, et al. (2011) High RASSF1A promoter methylation levels are predictive of poor prognosis in fine-needle aspirate washings of breast cancer lesions. Breast Cancer Res Treat 129: 1-9.
    • (2011) Breast Cancer Res Treat , vol.129 , pp. 1-9
    • Martins, A.T.1    Monteiro, P.2    Ramalho-Carvalho, J.3    Costa, V.L.4    Dinis-Ribeiro, M.5
  • 21
    • 84875493141 scopus 로고    scopus 로고
    • Combined RASSF1A and RASSF2A Promoter Methylation Analysis as Diagnostic Biomarker for Bladder Cancer
    • Meng W, Huebner A, Shabsigh A, Chakravarti A, Lautenschlaeger T, (2012) Combined RASSF1A and RASSF2A Promoter Methylation Analysis as Diagnostic Biomarker for Bladder Cancer. Mol Biol Int 2012: 701814.
    • (2012) Mol Biol Int , vol.2012 , pp. 701814
    • Meng, W.1    Huebner, A.2    Shabsigh, A.3    Chakravarti, A.4    Lautenschlaeger, T.5
  • 22
    • 84856557430 scopus 로고    scopus 로고
    • Methylated RASSF1a is the first specific DNA marker for minimal residual disease testing in neuroblastoma
    • Stutterheim J, Ichou FA, den Ouden E, Versteeg R, Caron HN, et al. (2012) Methylated RASSF1a is the first specific DNA marker for minimal residual disease testing in neuroblastoma. Clin Cancer Res 18: 808-814.
    • (2012) Clin Cancer Res , vol.18 , pp. 808-814
    • Stutterheim, J.1    Ichou, F.A.2    den Ouden, E.3    Versteeg, R.4    Caron, H.N.5
  • 23
    • 84862224603 scopus 로고    scopus 로고
    • The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma
    • Djos A, Martinsson T, Kogner P, Caren H, (2012) The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma. Mol Cancer 11: 40.
    • (2012) Mol Cancer , vol.11 , pp. 40
    • Djos, A.1    Martinsson, T.2    Kogner, P.3    Caren, H.4
  • 24
    • 67651093725 scopus 로고    scopus 로고
    • The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias
    • Hesson LB, Dunwell TL, Cooper WN, Catchpoole D, Brini AT, et al. (2009) The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias. Mol Cancer 8: 42.
    • (2009) Mol Cancer , vol.8 , pp. 42
    • Hesson, L.B.1    Dunwell, T.L.2    Cooper, W.N.3    Catchpoole, D.4    Brini, A.T.5
  • 25
    • 70349174971 scopus 로고    scopus 로고
    • The RASSF proteins in cancer; from epigenetic silencing to functional characterization
    • Richter AM, Pfeifer GP, Dammann RH, (2009) The RASSF proteins in cancer; from epigenetic silencing to functional characterization. Biochim Biophys Acta 1796: 114-128.
    • (2009) Biochim Biophys Acta , vol.1796 , pp. 114-128
    • Richter, A.M.1    Pfeifer, G.P.2    Dammann, R.H.3
  • 26
    • 64549157275 scopus 로고    scopus 로고
    • Rassf3 is responsible in part for resistance to mammary tumor development in neu transgenic mice
    • Jacquemart IC, Springs AE, Chen WY, (2009) Rassf3 is responsible in part for resistance to mammary tumor development in neu transgenic mice. Int J Oncol 34: 517-528.
    • (2009) Int J Oncol , vol.34 , pp. 517-528
    • Jacquemart, I.C.1    Springs, A.E.2    Chen, W.Y.3
  • 27
    • 53549104134 scopus 로고    scopus 로고
    • MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment
    • Pelizzola M, Koga Y, Urban AE, Krauthammer M, Weissman S, et al. (2008) MEDME: an experimental and analytical methodology for the estimation of DNA methylation levels based on microarray derived MeDIP-enrichment. Genome Res 18: 1652-1659.
    • (2008) Genome Res , vol.18 , pp. 1652-1659
    • Pelizzola, M.1    Koga, Y.2    Urban, A.E.3    Krauthammer, M.4    Weissman, S.5
  • 28
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman JG, Baylin SB, (2003) Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349: 2042-2054.
    • (2003) N Engl J Med , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 29
    • 0037129308 scopus 로고    scopus 로고
    • RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1
    • Tommasi S, Dammann R, Jin SG, Zhang XF, Avruch J, et al. (2002) RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1. Oncogene 21: 2713-2720.
    • (2002) Oncogene , vol.21 , pp. 2713-2720
    • Tommasi, S.1    Dammann, R.2    Jin, S.G.3    Zhang, X.F.4    Avruch, J.5
  • 30
    • 46949093338 scopus 로고    scopus 로고
    • The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex
    • Song MS, Song SJ, Kim SY, Oh HJ, Lim DS, (2008) The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex. EMBO J 27: 1863-1874.
    • (2008) EMBO J , vol.27 , pp. 1863-1874
    • Song, M.S.1    Song, S.J.2    Kim, S.Y.3    Oh, H.J.4    Lim, D.S.5
  • 32
    • 79953067459 scopus 로고    scopus 로고
    • Lineage-specific restraint of pituitary gonadotroph cell adenoma growth
    • Chesnokova V, Zonis S, Zhou C, Ben-Shlomo A, Wawrowsky K, et al. (2011) Lineage-specific restraint of pituitary gonadotroph cell adenoma growth. PLoS One 6: e17924.
    • (2011) PLoS One , vol.6
    • Chesnokova, V.1    Zonis, S.2    Zhou, C.3    Ben-Shlomo, A.4    Wawrowsky, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.