-
1
-
-
55249096942
-
Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv 1 (SLC2A9) in humans
-
Anzai N. Ichida K. Jutabha P. Kimura T. Babu E. Jin C.J. et al. (2008) Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv 1 (SLC2A9) in humans. J Biol Chem 283: 26834–26838.
-
(2008)
J Biol Chem
, vol.283
, pp. 26834-26838
-
-
Anzai, N.1
Ichida, K.2
Jutabha, P.3
Kimura, T.4
Babu, E.5
Jin, C.J.6
-
2
-
-
62349123738
-
Tophus response to pegloticase (PGL) therapy: pooled results from GOUT 1 and GOUT2, PGL phase 3 randomized, double blind, placebo-controlled trials
-
Baraf H. Becker M. Edwards N. Gutierrez-Urena S. Sundy J. Treadwell E. et al. (2008 a) Tophus response to pegloticase (PGL) therapy: pooled results from GOUT 1 and GOUT2, PGL phase 3 randomized, double blind, placebo-controlled trials. Arthritis Rheum 58: S176.
-
(2008)
Arthritis Rheum
, vol.58
, pp. S176
-
-
Baraf, H.1
Becker, M.2
Edwards, N.3
Gutierrez-Urena, S.4
Sundy, J.5
Treadwell, E.6
-
3
-
-
55849118787
-
Resolution of gouty tophi after twelve weeks of pegloticase treatment
-
Baraf H. Matsumoto A. Maroli A. Waltrip R. (2008 b) Resolution of gouty tophi after twelve weeks of pegloticase treatment. Arthritis Rheum 58: 3632–3634.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3632-3634
-
-
Baraf, H.1
Matsumoto, A.2
Maroli, A.3
Waltrip, R.4
-
4
-
-
77953729446
-
The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial
-
Becker M. Schumacher H. Espinoza L. Wells A. MacDonald P. Lioyd E. et al. (2010) The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. Arthritis Res Ther 12: R63.
-
(2010)
Arthritis Res Ther
, vol.12
, pp. R63
-
-
Becker, M.1
Schumacher, H.2
Espinoza, L.3
Wells, A.4
MacDonald, P.5
Lioyd, E.6
-
5
-
-
67149083327
-
Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout
-
Becker M. Schumacher H. MacDonald P. Lloyd E. Lademacher C. (2009) Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout. J Rheumatol 36: 1273–1282.
-
(2009)
J Rheumatol
, vol.36
, pp. 1273-1282
-
-
Becker, M.1
Schumacher, H.2
MacDonald, P.3
Lloyd, E.4
Lademacher, C.5
-
8
-
-
62349121751
-
Immunoreactivity and clinical response to pegloticase (PGL): pooled data from GOUT 1 and GOUT2, PGL phase 3 randomized, double blind, placebo-controlled trials
-
Becker M. Treadwell E. Baraf H. Edwards N. Gutierrez-Urena S. Sundy J. et al. (2008) Immunoreactivity and clinical response to pegloticase (PGL): pooled data from GOUT 1 and GOUT2, PGL phase 3 randomized, double blind, placebo-controlled trials. Arthritis Rheum 58: S880.
-
(2008)
Arthritis Rheum
, vol.58
, pp. S880
-
-
Becker, M.1
Treadwell, E.2
Baraf, H.3
Edwards, N.4
Gutierrez-Urena, S.5
Sundy, J.6
-
9
-
-
10044275104
-
Colchicine for prophylaxis of acute flares when initiating allopurinol for chronic gouty arthritis
-
Borstad G. Bryant L. Abel M. Scroggle D. Harris M. Alloway J. (2004) Colchicine for prophylaxis of acute flares when initiating allopurinol for chronic gouty arthritis. J Rheumatol 31: 2429–2432.
-
(2004)
J Rheumatol
, vol.31
, pp. 2429-2432
-
-
Borstad, G.1
Bryant, L.2
Abel, M.3
Scroggle, D.4
Harris, M.5
Alloway, J.6
-
10
-
-
84964229941
-
Pharmacological inhibition of interleukin-1 receptor-associated kinase-4 reduces inflammation in a murine model of gout and is consistent with IL-1 signaling blockade
-
Bree A. Phillips K. Benson M. Dower K. Shen M. Lee K. et al. (2011) Pharmacological inhibition of interleukin-1 receptor-associated kinase-4 reduces inflammation in a murine model of gout and is consistent with IL-1 signaling blockade. Arthritis Rheum 63(Suppl. 10): 1621.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1621
-
-
Bree, A.1
Phillips, K.2
Benson, M.3
Dower, K.4
Shen, M.5
Lee, K.6
-
11
-
-
79151481493
-
Gout therapeutics: new drugs for an old disease
-
Burns C. Wortmann R. (2011) Gout therapeutics: new drugs for an old disease. Lancet 377: 165–177.
-
(2011)
Lancet
, vol.377
, pp. 165-177
-
-
Burns, C.1
Wortmann, R.2
-
14
-
-
33746747096
-
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
-
Chen C. Shi Y. Hearn A. Fitzgerald K. Golenbock D. Reed G. et al. (2006) MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest 116: 2262–2271.
-
(2006)
J Clin Invest
, vol.116
, pp. 2262-2271
-
-
Chen, C.1
Shi, Y.2
Hearn, A.3
Fitzgerald, K.4
Golenbock, D.5
Reed, G.6
-
15
-
-
75749087687
-
A prescription for lifestyle change in patients with hyperuricemia and gout
-
Choi H. (2010) A prescription for lifestyle change in patients with hyperuricemia and gout. Curr Opin Rheumatol 22: 165–172.
-
(2010)
Curr Opin Rheumatol
, vol.22
, pp. 165-172
-
-
Choi, H.1
-
16
-
-
1942471074
-
Alcohol intake and risk of incident gout in men: a prospective study
-
Choi H. Atkinson K. Karlson E. Willett W. Curhan G. (2004) Alcohol intake and risk of incident gout in men: a prospective study. Lancet 363: 1277–1281.
-
(2004)
Lancet
, vol.363
, pp. 1277-1281
-
-
Choi, H.1
Atkinson, K.2
Karlson, E.3
Willett, W.4
Curhan, G.5
-
17
-
-
0034097204
-
Renal transplant-associated hyperuricemia and gout
-
Clive D. (2000) Renal transplant-associated hyperuricemia and gout. J Am Soc Nephrol 11: 974–979.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 974-979
-
-
Clive, D.1
-
19
-
-
62349095648
-
Use of imaging to evaluate gout and other crystal deposition disorders
-
Dalbeth N. McQueen F.M. (2009) Use of imaging to evaluate gout and other crystal deposition disorders. Curr Opin Rheumatol 21: 124–131.
-
(2009)
Curr Opin Rheumatol
, vol.21
, pp. 124-131
-
-
Dalbeth, N.1
McQueen, F.M.2
-
20
-
-
61349163769
-
Crystal ball gazing: new therapeutic targets for hyperuricaemia and gout
-
Dalbeth N. Merriman T. (2009) Crystal ball gazing: new therapeutic targets for hyperuricaemia and gout. Rheumatology 48: 222–226.
-
(2009)
Rheumatology
, vol.48
, pp. 222-226
-
-
Dalbeth, N.1
Merriman, T.2
-
21
-
-
34748917556
-
Allopurinol dosing in renal impairment: walking the tightrope between adequate urate lowering and adverse events
-
Dalbeth N. Stamp L. (2007) Allopurinol dosing in renal impairment: walking the tightrope between adequate urate lowering and adverse events. Semin Dial 20: 391–395.
-
(2007)
Semin Dial
, vol.20
, pp. 391-395
-
-
Dalbeth, N.1
Stamp, L.2
-
22
-
-
0023178197
-
Interleukin 1 (IL 1) as a mediator of crystal arthritis. Stimulation of T cell and synovial fibroblast mitogenesis by urate crystal-induced IL-1
-
Di Giovine F. Malawista S. Nuki G. Duff G. (1987) Interleukin 1 (IL 1) as a mediator of crystal arthritis. Stimulation of T cell and synovial fibroblast mitogenesis by urate crystal-induced IL-1. J Immunol 138: 3213–3218.
-
(1987)
J Immunol
, vol.138
, pp. 3213-3218
-
-
Di Giovine, F.1
Malawista, S.2
Nuki, G.3
Duff, G.4
-
23
-
-
0033936010
-
Beneficial effects of weight loss associated with moderate calorie / carbohydrate restriction, and increased proportional intake of protein and unsaturated fat on serum urate and lipoprotein levels in gout: A pilot study
-
Dessein P. Shipton E. Stanwix A. Joffe B. Ramokgadi J. (2000) Beneficial effects of weight loss associated with moderate calorie / carbohydrate restriction, and increased proportional intake of protein and unsaturated fat on serum urate and lipoprotein levels in gout: A pilot study. Ann Rheum Dis 59: 539–543.
-
(2000)
Ann Rheum Dis
, vol.59
, pp. 539-543
-
-
Dessein, P.1
Shipton, E.2
Stanwix, A.3
Joffe, B.4
Ramokgadi, J.5
-
24
-
-
46749102824
-
Urate transport across the apical membrane of renal proximal tubules
-
Endou H. Anzai N. (2008) Urate transport across the apical membrane of renal proximal tubules. Nucleosides Nucleotides Nucleic Acids 27: 578–584.
-
(2008)
Nucleosides Nucleotides Nucleic Acids
, vol.27
, pp. 578-584
-
-
Endou, H.1
Anzai, N.2
-
25
-
-
0037161834
-
Molecular identification of a renal urate anion exchanger that regulates blood urate levels
-
Enomoto A. Kimura H. Chairoungdu A. Shigeta Y. Jutabha P. Cha S. et al. (2002) Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 417: 447–452.
-
(2002)
Nature
, vol.417
, pp. 447-452
-
-
Enomoto, A.1
Kimura, H.2
Chairoungdu, A.3
Shigeta, Y.4
Jutabha, P.5
Cha, S.6
-
26
-
-
0035147111
-
Efficacy and safety of desensitization to allopurinol following cutaneous reactions
-
Fam A. Dunne S. Iazzetta J. Paton T. (2001) Efficacy and safety of desensitization to allopurinol following cutaneous reactions. Arthritis Rheum 44: 231–238.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 231-238
-
-
Fam, A.1
Dunne, S.2
Iazzetta, J.3
Paton, T.4
-
27
-
-
0013919965
-
Effects of allopurinol, a xanthine oxidase inhibitor, and sulfinpyrazone upon the urinary and serum urate concentrations in eight patients with tophaceous gout
-
Goldfarb E. Smythe C. (2007) Effects of allopurinol, a xanthine oxidase inhibitor, and sulfinpyrazone upon the urinary and serum urate concentrations in eight patients with tophaceous gout. Arthritis Rheum 9: 414–423.
-
(2007)
Arthritis Rheum
, vol.9
, pp. 414-423
-
-
Goldfarb, E.1
Smythe, C.2
-
28
-
-
84875518780
-
Arhalofenate, a potential novel treatment for hyperuricemia, with or without metabolic co-morbidities, in patients with gout: meta-analysis of urate lowering in four phase 2 studies in type 2 diabetes
-
Gopal C. Saha G. Karpf D. Choi Y. Roberts B. (2011) Arhalofenate, a potential novel treatment for hyperuricemia, with or without metabolic co-morbidities, in patients with gout: meta-analysis of urate lowering in four phase 2 studies in type 2 diabetes. Arthritis Rheum 63(Suppl. 10): 2584.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 2584
-
-
Gopal, C.1
Saha, G.2
Karpf, D.3
Choi, Y.4
Roberts, B.5
-
29
-
-
67650421494
-
T cells dampen innate immune responses through inhibition of NLRP 1 and NLRP 3 inflammasomes
-
Guard G. Dostert C. Staehli F. Cabalzar K. Castillo R. Tardivel A. et al. (2009) T cells dampen innate immune responses through inhibition of NLRP 1 and NLRP 3 inflammasomes. Nature 460: 270–273.
-
(2009)
Nature
, vol.460
, pp. 270-273
-
-
Guard, G.1
Dostert, C.2
Staehli, F.3
Cabalzar, K.4
Castillo, R.5
Tardivel, A.6
-
30
-
-
84993724591
-
Safety and efficacy of long-term pegloticase (KRYSTEXXA™) treatment in adult patients with chronic gout refractory to conventional therapy
-
Hamburger S. Lipsky P. Simon L. (2010) Safety and efficacy of long-term pegloticase (KRYSTEXXA™) treatment in adult patients with chronic gout refractory to conventional therapy. Arthritis Rheum 62(Suppl. 10): L12.
-
(2010)
Arthritis Rheum
, vol.62
, pp. L12
-
-
Hamburger, S.1
Lipsky, P.2
Simon, L.3
-
31
-
-
0021366307
-
Severe allopurinol toxicity
-
Hande K. Noone R. Stone W. (1984) Severe allopurinol toxicity. Am J Med 76: 47–56.
-
(1984)
Am J Med
, vol.76
, pp. 47-56
-
-
Hande, K.1
Noone, R.2
Stone, W.3
-
32
-
-
50249215856
-
The diagnosis of gout and gouty arthritis
-
Hensch P. (1936) The diagnosis of gout and gouty arthritis. J Lab Clin Med 220: 48–55.
-
(1936)
J Lab Clin Med
, vol.220
, pp. 48-55
-
-
Hensch, P.1
-
36
-
-
47649130363
-
A benefit-risk assessment of benzbromarone in the treatment of gout. Was its withdrawal from the market in the best interest of patients?
-
Lee M. Graham G. Williams K. Day R. (2008) A benefit-risk assessment of benzbromarone in the treatment of gout. Was its withdrawal from the market in the best interest of patients? Drug Saf 31: 643–665.
-
(2008)
Drug Saf
, vol.31
, pp. 643-665
-
-
Lee, M.1
Graham, G.2
Williams, K.3
Day, R.4
-
37
-
-
25444454295
-
Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation
-
Liu-Bryan R. Scott P. Sydlaske A. Rose D. Terkeltaub R. (2005) Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation. Arthritis Rheum 52: 2936–2946.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2936-2946
-
-
Liu-Bryan, R.1
Scott, P.2
Sydlaske, A.3
Rose, D.4
Terkeltaub, R.5
-
38
-
-
0035093686
-
Treatment of chronic gout. Can we determine when urate stores are depleted enough to prevent attacks of gout?
-
Li-Yu J. Clayburne G. Sieck M. Beutler A. Rull M. Eisner E. et al. (2001) Treatment of chronic gout. Can we determine when urate stores are depleted enough to prevent attacks of gout? J Rheumatol 28: 577–580.
-
(2001)
J Rheumatol
, vol.28
, pp. 577-580
-
-
Li-Yu, J.1
Clayburne, G.2
Sieck, M.3
Beutler, A.4
Rull, M.5
Eisner, E.6
-
39
-
-
82655172882
-
Inflammatory gout: observations over a half-century
-
Malawista S. de Boisfleury A. Naccache P. (2011) Inflammatory gout: observations over a half-century. FASEB J 25: 4073–4078.
-
(2011)
FASEB J
, vol.25
, pp. 4073-4078
-
-
Malawista, S.1
de Boisfleury, A.2
Naccache, P.3
-
40
-
-
58249116545
-
Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout
-
Martin W. Walton M. Harper J. (2009) Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout. Arthritis Rheum 60: 281–289.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 281-289
-
-
Martin, W.1
Walton, M.2
Harper, J.3
-
41
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP 3 inflammasome
-
Martinon F. Petrilli V. Mayor A. Tardivel A. Tschopp J. (2006) Gout-associated uric acid crystals activate the NALP 3 inflammasome. Nature 440: 237–241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
42
-
-
77952287367
-
Targeting IL-1β in disease; the expanding role of NLRP 3 inflammasome
-
Mitroulis M. Skendros P. Ritis K. (2010) Targeting IL-1β in disease; the expanding role of NLRP 3 inflammasome. Eur J Int Med 21: 157–163.
-
(2010)
Eur J Int Med
, vol.21
, pp. 157-163
-
-
Mitroulis, M.1
Skendros, P.2
Ritis, K.3
-
43
-
-
0036615827
-
Update on colchicine and its mechanism of action
-
Molad Y. (2002) Update on colchicine and its mechanism of action. Curr Rheum Rep 4: 252–256.
-
(2002)
Curr Rheum Rep
, vol.4
, pp. 252-256
-
-
Molad, Y.1
-
45
-
-
0016201345
-
Prophylactic colchicine therapy of intercritical gout. A placebo-controlled study of probenecid-treated patients
-
Paulus H. Schlosstein L. Godfrey R. Klinenberg J. Bluestone R. (1974) Prophylactic colchicine therapy of intercritical gout. A placebo-controlled study of probenecid-treated patients. Arthritis Rheum 17: 609–614.
-
(1974)
Arthritis Rheum
, vol.17
, pp. 609-614
-
-
Paulus, H.1
Schlosstein, L.2
Godfrey, R.3
Klinenberg, J.4
Bluestone, R.5
-
46
-
-
0031662935
-
Efficacy of allopurinol and benzbromarone for the control of hyperuricemia: A pathogenic approach to the treatment of primary chronic gout
-
Perez-Ruiz F. Alonso-Ruiz A. Calabozo M. Herrero-Beites A. Garcia-Erauskin G. Ruiz-Lucea E. (1998) Efficacy of allopurinol and benzbromarone for the control of hyperuricemia: A pathogenic approach to the treatment of primary chronic gout. Ann Rheum Dis 57: 545–549.
-
(1998)
Ann Rheum Dis
, vol.57
, pp. 545-549
-
-
Perez-Ruiz, F.1
Alonso-Ruiz, A.2
Calabozo, M.3
Herrero-Beites, A.4
Garcia-Erauskin, G.5
Ruiz-Lucea, E.6
-
47
-
-
0033668058
-
Improvement in renal function in patients with chronic gout after proper control of hyperuricemia and gouty bouts
-
Perez-Ruiz F. Calabozo C. Herrero-Beites A. Garcia-Erauskin G. Pijoan J. (2000) Improvement in renal function in patients with chronic gout after proper control of hyperuricemia and gouty bouts. Nephron 86: 287–291.
-
(2000)
Nephron
, vol.86
, pp. 287-291
-
-
Perez-Ruiz, F.1
Calabozo, C.2
Herrero-Beites, A.3
Garcia-Erauskin, G.4
Pijoan, J.5
-
49
-
-
80054070928
-
The epidemiology of uric acid and fructose
-
Rho Y. Zhu Y. Choi H. (2011) The epidemiology of uric acid and fructose. Semin Nephrol 31: 410–419.
-
(2011)
Semin Nephrol
, vol.31
, pp. 410-419
-
-
Rho, Y.1
Zhu, Y.2
Choi, H.3
-
50
-
-
35148881765
-
Rasburicase for tophaceous gout not treatable with allopurinol: An exploratory study
-
Richette P. Briere C. Honene-Claviert V. Loeuille D. Bardin T. (2007) Rasburicase for tophaceous gout not treatable with allopurinol: An exploratory study. J Rheumatol 34: 1093–1098.
-
(2007)
J Rheumatol
, vol.34
, pp. 1093-1098
-
-
Richette, P.1
Briere, C.2
Honene-Claviert, V.3
Loeuille, D.4
Bardin, T.5
-
52
-
-
79953094557
-
Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat gouty arthritis by suppressing inflammation: results of a randomized, dose-ranging study
-
Schlesinger N. de Meulemeester M. Pikhlak A. Yücel A. Richard D. Murphy V. et al. (2011 a) Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat gouty arthritis by suppressing inflammation: results of a randomized, dose-ranging study. Arthritis Res Ther 13: R53.
-
(2011)
Arthritis Res Ther
, vol.13
, pp. R53
-
-
Schlesinger, N.1
de Meulemeester, M.2
Pikhlak, A.3
Yücel, A.4
Richard, D.5
Murphy, V.6
-
53
-
-
79957646006
-
Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study
-
Schlesinger N. Mysler E. Lin H. de Meulemeester M. Rovensky J. Arulmani U. et al. (2011 b) Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study. Ann Rheum Dis 70: 1264–1271.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1264-1271
-
-
Schlesinger, N.1
Mysler, E.2
Lin, H.3
de Meulemeester, M.4
Rovensky, J.5
Arulmani, U.6
-
54
-
-
58749106802
-
Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study
-
Schumacher H. Becker M. Lloyd E. MacDonald P. Lademacher C. (2009) Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study. Rheumatology 48: 188–194.
-
(2009)
Rheumatology
, vol.48
, pp. 188-194
-
-
Schumacher, H.1
Becker, M.2
Lloyd, E.3
MacDonald, P.4
Lademacher, C.5
-
55
-
-
56049101851
-
Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel group trial
-
Schumacher H. Becker M. Wortmann R. MacDonald P. Hunt B. Streit J. et al. (2008) Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel group trial. Arthritis Rheum 59: 1540–1548.
-
(2008)
Arthritis Rheum
, vol.59
, pp. 1540-1548
-
-
Schumacher, H.1
Becker, M.2
Wortmann, R.3
MacDonald, P.4
Hunt, B.5
Streit, J.6
-
56
-
-
84857774498
-
Rilonacept (Interleukin-1 Trap) in the prevention of acute gout flares during initiation of urate-lowering therapy results of a phase II randomized, double-blind, placebo-controlled trial
-
Schumacher H. Sundy J. Terkeltaub R. Knapp H. Mellis S. Stahl N. et al. (2012) Rilonacept (Interleukin-1 Trap) in the prevention of acute gout flares during initiation of urate-lowering therapy results of a phase II randomized, double-blind, placebo-controlled trial. Arthritis Rheum 64: 876–884.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 876-884
-
-
Schumacher, H.1
Sundy, J.2
Terkeltaub, R.3
Knapp, H.4
Mellis, S.5
Stahl, N.6
-
57
-
-
33750421914
-
Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals
-
Scott P. Ma H. Viriyakosol S. Terkeltaub R. Liu-Bryan R. (2006) Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. J Immunol 177: 6370–6378.
-
(2006)
J Immunol
, vol.177
, pp. 6370-6378
-
-
Scott, P.1
Ma, H.2
Viriyakosol, S.3
Terkeltaub, R.4
Liu-Bryan, R.5
-
58
-
-
36549089052
-
PEG-uricase in the management of treatment-resistant gout and hyperuricemia
-
Sherman M. Saifer M. Perez-Ruiz F. (2008) PEG-uricase in the management of treatment-resistant gout and hyperuricemia. Adv Drug Deliv Rev 60: 59–68.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 59-68
-
-
Sherman, M.1
Saifer, M.2
Perez-Ruiz, F.3
-
59
-
-
0142031503
-
New standards for uric acid excretion: evidence for an inducible transporter
-
Simkin P. (2003) New standards for uric acid excretion: evidence for an inducible transporter. Arthritis Care Res 49: 735–736.
-
(2003)
Arthritis Care Res
, vol.49
, pp. 735-736
-
-
Simkin, P.1
-
60
-
-
29244447160
-
Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid
-
Siu Y. Leung K. Tong M. Kwan T. (2006) Use of allopurinol in slowing the progression of renal disease through its ability to lower serum uric acid. Am J Kidney Dis 47: 51–59.
-
(2006)
Am J Kidney Dis
, vol.47
, pp. 51-59
-
-
Siu, Y.1
Leung, K.2
Tong, M.3
Kwan, T.4
-
61
-
-
77957688721
-
Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis. Results of a multicenter, phase II, dose-ranging study
-
So A. de Meulemeester M. Pikhlak A. Yücel A. Richard D. Murphy V. et al. (2010) Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis. Results of a multicenter, phase II, dose-ranging study. Arthritis Rheum 62: 3064–3076.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 3064-3076
-
-
So, A.1
de Meulemeester, M.2
Pikhlak, A.3
Yücel, A.4
Richard, D.5
Murphy, V.6
-
63
-
-
84905219493
-
Starting dose, but not maximum maintenance dose, is a risk factor for allopurinol hypersensitivity syndrome: a proposed nomogram for safe starting dosing of allopurinol
-
Stamp L. Taylor W. Jones P. Dockerty J. Drake J. Frampton C. et al. (2011) Starting dose, but not maximum maintenance dose, is a risk factor for allopurinol hypersensitivity syndrome: a proposed nomogram for safe starting dosing of allopurinol. Arthritis Rheum 63(Suppl. 10): 25.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 25
-
-
Stamp, L.1
Taylor, W.2
Jones, P.3
Dockerty, J.4
Drake, J.5
Frampton, C.6
-
65
-
-
80051749331
-
Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials
-
Sundy J. Baraf H. Yood R. Edwards N. Gutierrez-Urena S. Treadwell E. et al. (2011) Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials. JAMA 306: 711–720.
-
(2011)
JAMA
, vol.306
, pp. 711-720
-
-
Sundy, J.1
Baraf, H.2
Yood, R.3
Edwards, N.4
Gutierrez-Urena, S.5
Treadwell, E.6
-
66
-
-
51849118368
-
Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment failure gout
-
Sundy J. Becker M. Baraf H. Barkhuizen A. Moreland L. Huang W. et al. (2008) Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment failure gout. Arthritis Rheum 58: 2882–2891.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2882-2891
-
-
Sundy, J.1
Becker, M.2
Baraf, H.3
Barkhuizen, A.4
Moreland, L.5
Huang, W.6
-
67
-
-
33947119693
-
Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout
-
Sundy J. Ganson N. Kelly S. Scarlett E. Rehrig C. Huang W. et al. (2007) Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout. Arthritis Rheum 56: 1021–1028.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1021-1028
-
-
Sundy, J.1
Ganson, N.2
Kelly, S.3
Scarlett, E.4
Rehrig, C.5
Huang, W.6
-
68
-
-
84875545131
-
Identification of specific amino acids in the uric acid transporter URAT 1 required for uricosuric-mediated inhibition
-
Tan P. Hyndman D. Miner J.N. (2011) Identification of specific amino acids in the uric acid transporter URAT 1 required for uricosuric-mediated inhibition. Arthritis Rheum 63(Suppl. 10): 1592.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1592
-
-
Tan, P.1
Hyndman, D.2
Miner, J.N.3
-
69
-
-
77950525312
-
High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study
-
Terkeltaub R. Furst D. Bennett K. Kook K. Crockett R. Davis M. (2010) High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study. Arthritis Rheum 62: 1060–1068.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1060-1068
-
-
Terkeltaub, R.1
Furst, D.2
Bennett, K.3
Kook, K.4
Crockett, R.5
Davis, M.6
-
70
-
-
70349402166
-
The IL-1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, nonrandomized, single-blind pilot study
-
Terkeltaub R. Sundy J. Schumacher H. Murphy F. Bookbinder S. Biedermann S. et al. (2009) The IL-1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, nonrandomized, single-blind pilot study. Ann Rheum Dis 68: 1613–1617.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1613-1617
-
-
Terkeltaub, R.1
Sundy, J.2
Schumacher, H.3
Murphy, F.4
Bookbinder, S.5
Biedermann, S.6
-
71
-
-
34447311936
-
Diagnosis of gout by ultrasound
-
Thiele R. Schlesinger N. (2007) Diagnosis of gout by ultrasound. Rheumatology 46: 1116–1121.
-
(2007)
Rheumatology
, vol.46
, pp. 1116-1121
-
-
Thiele, R.1
Schlesinger, N.2
-
72
-
-
70349379884
-
Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis
-
Torres R. MacDonald L. Croll S. Reinhardt J. Dore A. Stevens S. et al. (2009) Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis. Ann Rheum Dis 68: 1602–1608.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1602-1608
-
-
Torres, R.1
MacDonald, L.2
Croll, S.3
Reinhardt, J.4
Dore, A.5
Stevens, S.6
-
73
-
-
0014211418
-
Diagnostic value of the colchicine therapeutic trial
-
Wallace S. Bernstein D. Diamond H. (1967) Diagnostic value of the colchicine therapeutic trial. JAMA 199: 525–528.
-
(1967)
JAMA
, vol.199
, pp. 525-528
-
-
Wallace, S.1
Bernstein, D.2
Diamond, H.3
-
75
-
-
77953477599
-
Routine serum uric acid (SUA) monitoring predicts antibody-mediated loss of response and infusion reaction risk during pegloticase therapy
-
Wright D. Sundy J. Rosario-Jansen T. (2009) Routine serum uric acid (SUA) monitoring predicts antibody-mediated loss of response and infusion reaction risk during pegloticase therapy. Arthritis Rheum 60(Suppl. 10): 1104.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1104
-
-
Wright, D.1
Sundy, J.2
Rosario-Jansen, T.3
-
76
-
-
34347215843
-
High-resolution ultrasonography of the first metatarsal phalangeal joint in gout: a controlled study
-
Wright S. Filippucci E. McVeigh C. Grey A. McCarron M. Grassi W. et al. (2007) High-resolution ultrasonography of the first metatarsal phalangeal joint in gout: a controlled study. Ann Rheum Dis 66: 859–864.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 859-864
-
-
Wright, S.1
Filippucci, E.2
McVeigh, C.3
Grey, A.4
McCarron, M.5
Grassi, W.6
-
77
-
-
0032429567
-
The treatment of gout: The use of an analogy
-
Wortmann R. (1998) The treatment of gout: The use of an analogy. Am J Med 105: 513–514.
-
(1998)
Am J Med
, vol.105
, pp. 513-514
-
-
Wortmann, R.1
-
78
-
-
0024392731
-
Urate oxidase: primary structure and evolutionary implications
-
Wu X. Lee C. Muzny D. Caskey C. (1989) Urate oxidase: primary structure and evolutionary implications. Proc Natl Acad Sci USA 86: 9412–9416.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 9412-9416
-
-
Wu, X.1
Lee, C.2
Muzny, D.3
Caskey, C.4
-
79
-
-
0034817415
-
Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricemia and gout
-
Wurzner G. Gester J. Chiolero A. Maillard M. Fallab-Stubi C. Brunner H. et al. (2001) Comparative effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricemia and gout. J Hypertens 19: 1855–1860.
-
(2001)
J Hypertens
, vol.19
, pp. 1855-1860
-
-
Wurzner, G.1
Gester, J.2
Chiolero, A.3
Maillard, M.4
Fallab-Stubi, C.5
Brunner, H.6
-
81
-
-
0034795608
-
Effect of fenofibrate on plasma concentration and urinary excretion of purine bases and oxypurinol
-
Yamamoto T. Moriwaki Y. Tukahashi S. Tsutsumi Z. Hada T. (2001) Effect of fenofibrate on plasma concentration and urinary excretion of purine bases and oxypurinol. J Rheumatol 28: 2294–2297.
-
(2001)
J Rheumatol
, vol.28
, pp. 2294-2297
-
-
Yamamoto, T.1
Moriwaki, Y.2
Tukahashi, S.3
Tsutsumi, Z.4
Hada, T.5
-
82
-
-
0001117811
-
Efficacy of colchicine prophylaxis: Prevention of recurrent gouty arthritis over a mean period of five years in 208 gouty subjects
-
Yu T. Gutman A. (1961) Efficacy of colchicine prophylaxis: Prevention of recurrent gouty arthritis over a mean period of five years in 208 gouty subjects. Ann Intern Med 55: 179–192.
-
(1961)
Ann Intern Med
, vol.55
, pp. 179-192
-
-
Yu, T.1
Gutman, A.2
-
83
-
-
0014187863
-
Uric acid nephrolithiasis in gout: Predisposing factors
-
Yu T. Gutman A. (1967) Uric acid nephrolithiasis in gout: Predisposing factors. Ann Intern Med 67: 1133–1148.
-
(1967)
Ann Intern Med
, vol.67
, pp. 1133-1148
-
-
Yu, T.1
Gutman, A.2
-
84
-
-
33750374233
-
EULAR evidence based recommendations for gout. Part I: Diagnosis. Report of a task force of the standing committee for international clinical studies including therapeutics (ESCISIT)
-
Zhang W. Doherty M. Pascual E. Bardin T. Barskova V. Conaghan P. et al. (2006 a) EULAR evidence based recommendations for gout. Part I: Diagnosis. Report of a task force of the standing committee for international clinical studies including therapeutics (ESCISIT). Ann Rheum Dis 65: 1301–1311.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 1301-1311
-
-
Zhang, W.1
Doherty, M.2
Pascual, E.3
Bardin, T.4
Barskova, V.5
Conaghan, P.6
|