(+)-Episesamin inhibits adipogenesis and exerts anti-inflammatory effects in 3T3-L1 (pre)adipocytes by sustained Wnt signaling, down-regulation of PPARγ and induction of iNOS

Journal of Nutritional Biochemistry

Volumn 24, Issue 3, 2013, Pages 550-555

  Freise, Christian ^a   Trowitzsch Kienast, Wolfram ^b   Erben, Ulrike ^a   Seehofer, Daniel ^a   Kim, Ki Young ^c   Zeitz, Martin ^a   Ruehl, Martin ^a   Somasundaram, Rajan ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b BEUTH UNIVERSITY OF APPLIED SCIENCES   (Germany)

^c Wonkwang University   (South Korea)

Author keywords

(+) Episesamin; 3T3 L1; Adipogenesis; Inflammation; PPAR

Indexed keywords

ANTIINFLAMMATORY AGENT; BETA CATENIN; CASPASE 3; CASPASE 7; EPISESAMIN; FAT DROPLET; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN; WNT PROTEIN;

ADIPOGENESIS; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENZYME ACTIVITY; NONHUMAN; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BETA CATENIN; CASPASE 3; CASPASE 7; CELL DIFFERENTIATION; DIOXOLES; DOWN-REGULATION; GLUCOSE TRANSPORTER TYPE 4; INFLAMMATION; INTERLEUKIN-6; LIGNANS; LINDERA; LIPID METABOLISM; LIVER; MICE; NITRIC OXIDE SYNTHASE TYPE II; OBESITY; PHOSPHORYLATION; PLANT EXTRACTS; PPAR GAMMA; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WNT SIGNALING PATHWAY;

LINDERA OBTUSILOBA;

EID: 84875514735     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2012.02.004     Document Type: Article

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