Radical scavenging activity and vitexin content of vitex agnus-castus leaves and fruits

Fabad Journal of Pharmaceutical Sciences

Volumn 35, Issue 2, 2010, Pages 85-91

  Gökbulut, Alper ^a   Özhan, Onural ^a   Karacaoglu, Melek ^a   Sarer, Engin ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Antioxidant activity; DPPH; RP HPLC; Total phenolic content; Vitex agnus castus; Vitexin

Indexed keywords

EID: 84875474700     PISSN: 13004182     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Hoberg E, Meier B, Sticher O. Quantitative high performance liquid chromatographic analysis of casticin in the fruits of Vitex agnus-castus. Pharm Biol 39: 57-61, 2001.
2. Hoberg E, Meier B, Sticher O. An analytical high performance liquid chromatographic method for the determination of agnuside and p-hydroxybenzoic acid contents in agni-casti fructus. Phytochem Analysis 11: 327-329, 2000.
3. Şarer E, Gökbulut A. Determination of caffeic and chlorogenic acids in the leaves and fruits of Vitex agnus-castus. Turk J Pharm Sci 5: 167-174, 2008.
4. Proestos C, Sereli D, Komaitis M. Determination of phenolic compounds in aromatic plants by RP-HPLC and GC-MS. Food Chem 95: 44-52, 2006.
5. Wuttke W, Jarry H, Christoffel V, Spengler B, Seidlova-Wuttke D. Chaste-tree (Vitex agnus-castus) pharmacology and clinical indications. Phytomedicine 10: 348-357, 2003.
6. Van Die MD, Burger HG, Teede HJ, Bone KM. Vitex agnus-castus (Chaste-Tree/Berry) in the treatment of menapause-related complaints. J Altern Complem Med 15: 853-862, 2009.
7. Choudhary MI, Azizuddin, Jalil S, Nawaz SA, Khan KM, Tareen RB, Atta-ur-Rahman. Antiinflammatory and lipoxygenase inhibitorycompounds from Vitex agnus-castus. Phytother Res 23: 1336-1339, 2009.
8. Saǧlam H, Pabuçcuoǧlu A, Kivçak B. Antioxidant activity of Vitex agnus-castus L. extracts. Phytother Res 21: 1059-1060, 2007.
9. Azizuddin, Makhmoor T, Choudhary MI. Radical scavenging potential of compounds isolated from Vitex agnus-castus. Turk J Chem 34: 119-126, 2010.
10. Hajdu Z, Hohmann J, Forgo P, Martinek T, Dervarics M, Zupko I, Falkay G, Cossuta D, Mathe I. Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents. Phytother Res 21: 391-394, 2007.
11. Chen S-N, Friesen JB, Webster D, Nikolic D, Van Breemen RB, Wang ZJ, Fong HHS, Farnsworth NR, Pauli GF. Phytoconstituents from Vitex agnus-castus fruits. Fitoterapia 82: 528-533, 2011.
12. Kuruüzüm-Uz A, Ströch K, Demirezer, LÖ, Zeek A. Glucosides from Vitex agnus-castus. Phytochemistry 63: 959-964, 2003.
13. Ono M, Eguchi K, Konoshita M, Furusawa C, Sakamato J, Yasuda S, Ikeda T, Okawa M, Kinjo J, Yoshimitsu H, Nohara T. A new diterpenoid glucoside and two new diterpenoids from the fruit of Vitex agnus-castus. Chem Pharm Bull 59: 392-396, 2011.
14. Hirobe C, Qiao ZS, Takeya K, Itokawa H. Cytotoxic flavonoids from Vitex agnus-castus. Phytochemistry 46: 521-524, 1997.
15. Küçükboyaci N, Şener B. Two major flavonoids from the fruits of Vitex agnus-castus L. Turk J Pharm Sci 7: 119-126, 2010.
16. Kim JH, Lee BC, Kim JH, Sim GS, Lee DH, Lee KE, Yun YP, Pyo HB. The isolation and antioxidative effects of vitexin from Acer palmatum. Arch Pharm Res 28: 195-202, 2005.
17. Salvador MJ, Zucchi OLAD, Candido RC, Ito IY, Dias DA. In vitro antimicrobial activity of crude extracts and isolated constituents of Alternanthera maritima. Pharm Biol 42: 138-148, 2004.
18. Banskota AH, Tezuka Y, Adnyana IK, Xiong QB, Hase K, Tran KQ, Tanaka K, Saiki I, Kadota S. Hepatoprotective effect of Combretum quadrangulare and its constituents. Biol Pharm Bull 23: 456-460, 2000.
19. Ragone MI, Sella M, Conforti P, Volonte MG, Consolini AE. The spasmolytic effect of Aloysia citriodora, Palau (South American cedron) is partially due to its vitexin but not isovitexin on rat duedonums. J Ethnopharmacol 113: 258-266, 2007.
20. Li Y-L, Ma S-C, Yang Y-T, Ye S-M, But PP-H. Antiviral activities of flavonoids and organic acid from Trollius chinensis Bunge. J Ethnopharmacol 79: 365-368, 2002.
21. Gaitan E, Cooksey RC, Legan J, Lindsay RH. Antithyroid effects in vivo and in vitro of vitexin-AC-glucosylflavone in Millet. J Clin Endocr Metab 80: 1144-1147, 1995.
22. Peng X, Zheng Z, Cheng K-W, Shan F, Ren G-X, Chen F, Wang M. Inhibitory effect of mung bean extract and its constituents vitexin and isovitexin on the formation of advanced glycation endproducts. Food Chem 106: 475-481, 2008.
23. Zielinska D, Zielinski H. Antioxidant activity of flavone-C-glucosides determined by updated analytical strategies. Food Chem 124: 672-678, 2011.
24. Singleton VL, Orthofer R, Lamuela-Raventos RM. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Method Enzymol 299: 152-178, 1999.
25. Barros L, Baptista P, Ferreira ICFR. Effect of Lactarius piperatus fruiting body maturity stage on antioxidant activity measured by several biochemical assays. Food Chem Toxicol 45: 1731-1737, 2007.