Synthesis, preliminary structure-activity relationships, and in vitro biological evaluation of 6-aryl-3-amino-thieno[2,3-b]pyridine derivatives as potential anti-inflammatory agents

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 8, 2013, Pages 2349-2352

  Liu, Huan ^a   Li, Yi ^a   Wang, Xiang Ying ^a   Wang, Bo ^a   He, Hai Yun ^a   Liu, Ji Yan ^a   Xiang, Ming Li ^a   He, Jun ^a   Wu, Xiao Hua ^a   Yang, Li ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

6 Aryl 3 amino thieno 2,3 b pyridine derivatives; Anti inflammatory agent; Nitric oxide (NO); Structure activity relationships (SARs); Tumor necrosis factor (TNF )

Indexed keywords

ANTIINFLAMMATORY AGENT; NITRIC OXIDE; THIENOPYRIDINE DERIVATIVE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANTI-INFLAMMATORY AGENTS; NITRIC OXIDE; STRUCTURE-ACTIVITY RELATIONSHIP; THIENOPYRIDINES;

EID: 84875467361     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.02.059     Document Type: Article

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