-
1
-
-
0034723290
-
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
-
DOI 10.1074/jbc.275.4.2247
-
Friedman SL: Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000;275:2247-2250. (Pubitemid 30081976)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.4
, pp. 2247-2250
-
-
Friedman, S.L.1
-
2
-
-
0026643743
-
A T celldependent experimental liver injury in mice inducible by concanavalin A
-
Tiegs G, Hentschel J, Wendel A: A T celldependent experimental liver injury in mice inducible by concanavalin A. J Clin Invest 1992;90:196-203.
-
(1992)
J Clin Invest
, vol.90
, pp. 196-203
-
-
Tiegs, G.1
Hentschel, J.2
Wendel, A.3
-
3
-
-
0033694155
-
Importance of Kupffer cells for Tcell-dependent liver injury in mice
-
Schumann J, Wolf D, Pahl A, Brune K, Papadopoulos T, van Rooijen N, Tiegs G: Importance of Kupffer cells for Tcell-dependent liver injury in mice. Am J Pathol 2000;157:1671-1683.
-
(2000)
Am J Pathol
, vol.157
, pp. 1671-1683
-
-
Schumann, J.1
Wolf, D.2
Pahl, A.3
Brune, K.4
Papadopoulos, T.5
Van Rooijen, N.6
Tiegs, G.7
-
4
-
-
0028795171
-
Concanavalin A-induced Tcell-mediated hepatic injury in mice: The role of tumor necrosis factor
-
Gantner F, Leist M, Lohse AW, Germann PG, Tiegs G: Concanavalin A-induced Tcell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 1995;21:190-198.
-
(1995)
Hepatology
, vol.21
, pp. 190-198
-
-
Gantner, F.1
Leist, M.2
Lohse, A.W.3
Germann, P.G.4
Tiegs, G.5
-
5
-
-
0036830306
-
In vivo regulation of inducible NO synthase in immune-mediated liver injury in mice
-
DOI 10.1053/jhep.2002.36155
-
Koerber K, Sass G, Kiemer AK, Vollmar AM, Tiegs G: In vivo regulation of inducible NO synthase in immunemediated liver injury in mice. Hepatology 2002;36:1061-1069. (Pubitemid 35253421)
-
(2002)
Hepatology
, vol.36
, Issue.5
, pp. 1061-1069
-
-
Koerber, K.1
Sass, G.2
Kiemer, A.K.3
Vollmar, A.M.4
Tiegs, G.5
-
6
-
-
77957859388
-
Novel Thienopyridine Derivatives as Specific Antihepatocellular Carcinoma (HCC) Agents: Synthesis, Preliminary Structure-activity Relationships, and in vitro Biological Evaluation
-
Zeng XX, Zheng RL, Zhou T, He HY, Liu JY, Zheng Y, Tong AP, Xiang ML, Song, XR Yang SY, Yu LT, Wei YQ, Zhao YL, Yang L: Novel Thienopyridine Derivatives as Specific Antihepatocellular Carcinoma (HCC) Agents: Synthesis, Preliminary Structure-activity Relationships, and in vitro Biological Evaluation. Bioorgan Med Chem Letters 2010;20:6282-6285.
-
(2010)
Bioorgan Med Chem Letters
, vol.20
, pp. 6282-6285
-
-
Zeng, X.X.1
Zheng, R.L.2
Zhou, T.3
He, H.Y.4
Liu, J.Y.5
Zheng, Y.6
Tong, A.P.7
Xiang, M.L.8
Song, X.R.9
Yang, S.Y.10
Yu, L.T.11
Wei, Y.Q.12
Zhao, Y.L.13
Yang, L.14
-
7
-
-
0029874138
-
The NF-κB and IκB proteins: New discoveries and insights
-
DOI 10.1146/annurev.immunol.14.1.649
-
Baldwin AS Jr: The NF-kappa B and I kappa B proteins: new discoveries and insights Ann Rev Immunol 1996;14:649-683 (Pubitemid 26130197)
-
(1996)
Annual Review of Immunology
, vol.14
, pp. 649-683
-
-
Baldwin Jr., A.S.1
-
8
-
-
67650568967
-
Phosphoinositide 3-kinase inhibitor ameliorates concanavalin Ainduced hepatic injury in mice
-
Wang ZL, Wu XH, Song LF, Wang YS, Hu XH, Luo YF, Chen ZZ, Ke J, Peng XD, He CM, Zhang W, Chen LJ, Wei YQ: Phosphoinositide 3-kinase inhibitor ameliorates concanavalin Ainduced hepatic injury in mice Biochem Biophys Res Comm 2009;386:569-574
-
(2009)
Biochem Biophys Res Comm
, vol.386
, pp. 569-574
-
-
Wang, Z.L.1
Wu, X.H.2
Song, L.F.3
Wang, Y.S.4
Hu, X.H.5
Luo, Y.F.6
Chen, Z.Z.7
Ke, J.8
Peng, X.D.9
He, C.M.10
Zhang, W.11
Chen, L.J.12
Wei, Y.Q.13
-
9
-
-
0035040835
-
Amelioration of rat antigen-induced arthritis by liposomally conjugated methotrexate is accompanied by down-regulation of cytokine mRNA expression
-
Williams AS, Topley N, Dojcinov S, Richards PJ, Williams BD: Amelioration of rat antigen-induced arthritis by liposomally conjugated methotrexate is accompanied by down-regulation of cytokine mRNA expression Rheumatology 2001;40:375-383
-
(2001)
Rheumatology
, vol.40
, pp. 375-383
-
-
Williams, A.S.1
Topley, N.2
Dojcinov, S.3
Richards, P.J.4
Williams, B.D.5
-
10
-
-
0033901357
-
Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice
-
Hentze H, Gantner F, Kolb SA, Wendel A: Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice. Am J Pathol 2000;156:2045-2056. (Pubitemid 30641772)
-
(2000)
American Journal of Pathology
, vol.156
, Issue.6
, pp. 2045-2056
-
-
Hentze, H.1
Gantner, F.2
Kolb, S.A.3
Wendel, A.4
-
11
-
-
0242584926
-
Downregulation of NF-κB activation in human keratinocytes by melanogenic inhibitors
-
DOI 10.1016/S0923-1811(03)00039-2
-
Ahn KS, Moon KY, Lee J, Kim YS: Downregulation of NF-kappaB activation in human keratinocytes by melanogenic inhibitors. J Dermatol Sci 2003;31:193-201. (Pubitemid 36519153)
-
(2003)
Journal of Dermatological Science
, vol.31
, Issue.3
, pp. 193-201
-
-
Ahn, K.S.1
Moon, K.-Y.2
Lee, J.3
Kim, Y.S.4
-
12
-
-
0031470752
-
Modulation of human neutrophil inflammatory responses by nitric oxide: Studies in unprimed and LPS-primed cells
-
Nath J, Powledge A: Modulation of human neutrophil inflammatory responses by nitric oxide: studies in unprimed and LPSprimed cells. J Leuko Biol 1997;62:805-816. (Pubitemid 28015629)
-
(1997)
Journal of Leukocyte Biology
, vol.62
, Issue.6
, pp. 805-816
-
-
Nath, J.1
Powledge, A.2
-
13
-
-
0032742184
-
Interleukin-11 reduces T-cell-dependent experimental liver injury in mice
-
Bozza M, Bliss JL, Maylor R, Erickson J, Donnelly L, Bouchard P, Dorner AJ, Trepicchio WL: Interleukin-11 reduces T-cell-dependent experimental liver injury in mice. Hepatology 1999;30:1441-1447.
-
(1999)
Hepatology
, vol.30
, pp. 1441-1447
-
-
Bozza, M.1
Bliss, J.L.2
Maylor, R.3
Erickson, J.4
Donnelly, L.5
Bouchard, P.6
Dorner, A.J.7
Trepicchio, W.L.8
-
14
-
-
0037064538
-
The role of cytokines in liver failure and regeneration: Potential new molecular therapies
-
DOI 10.1016/S0167-4889(02)00326-9, PII S0167488902003269
-
Galun E, Axelrod JH: The role of cytokines in liver failure and regeneration: potential new molecular therapies. Biochim Biophys Acta 2002;1592:345-358. (Pubitemid 35284888)
-
(2002)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1592
, Issue.3
, pp. 345-358
-
-
Galun, E.1
Axelrod, J.H.2
-
15
-
-
26444535295
-
The kinase inhibitor imatinib mesylate inhibits TNF-α production in vitro and prevents TNF-dependent acute hepatic inflammation
-
DOI 10.1073/pnas.0501758102
-
Wolf AM, Wolf D, Rumpold H, Ludwiczek S, Enrich B, Gastl G, Weiss G, Tilg H: The kinase inhibitor imatinib mesylate inhibits TNF-production in vitro and prevents TNF-dependent acute hepatic inflammation. PNAS 2005;102:13622-13627. (Pubitemid 41420898)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.38
, pp. 13622-13627
-
-
Wolf, A.M.1
Wolf, D.2
Rumpold, H.3
Ludwiczek, S.4
Enrich, B.5
Gastl, G.6
Weiss, G.7
Tilg, H.8
-
16
-
-
66049162280
-
Induction of overexpression of the 27-and 70-kDa heat shock proteins by bicyclol attenuates concanavalin A-Induced liver injury through suppression of nuclear factorkappaB in mice
-
Bao XQ, Liu GT: Induction of overexpression of the 27-and 70-kDa heat shock proteins by bicyclol attenuates concanavalin A-Induced liver injury through suppression of nuclear factorkappaB in mice. Molecular pharmacology 2009;75:1180-1188.
-
(2009)
Molecular Pharmacology
, vol.75
, pp. 1180-1188
-
-
Bao, X.Q.1
Liu, G.T.2
-
18
-
-
33646732608
-
Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease
-
Jernberg T, Payne CD, Winters KJ, Darstein C, Brandt JT, Jakubowski JA, Naganuma H, Siegbahn A, Wallentin L: Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease. Eur Heart J 2006;27:1166-1173.
-
(2006)
Eur Heart J
, vol.27
, pp. 1166-1173
-
-
Jernberg, T.1
Payne, C.D.2
Winters, K.J.3
Darstein, C.4
Brandt, J.T.5
Jakubowski, J.A.6
Naganuma, H.7
Siegbahn, A.8
Wallentin, L.9
-
19
-
-
0037243921
-
The thienopyridine derivatives (platelet adenosine diphosphate receptor antagonists), pharmacology and clinical developments
-
DOI 10.1046/j.1365-2044.2003.02960.x
-
Kam PCA, Nethery CM: The thienopyridine derivatives (platelet adenosine diphosphate receptor antagonists), pharmacology and clinical developments. Anaesthesia 2003;58:28-35. (Pubitemid 36113325)
-
(2003)
Anaesthesia
, vol.58
, Issue.1
, pp. 28-35
-
-
Kam, P.C.A.1
Nethery, C.M.2
-
20
-
-
17844392652
-
Resistin, an adipokine with potent proinflammatory properties
-
Bokarewa M, Nagaev I, Dahlberg L, Smith U, Tarkowski A: Resistin, an Adipokine with Potent Proinflammatory Properties J Immunol 2005;174:5789-5795 (Pubitemid 40593223)
-
(2005)
Journal of Immunology
, vol.174
, Issue.9
, pp. 5789-5795
-
-
Bokarewa, M.1
Nagaev, I.2
Dahlberg, L.3
Smith, U.4
Tarkowski, A.5
-
21
-
-
15044352862
-
The implantation of Taenia solium metacestodes in mice induces down-modulation of T-cell proliferation and cytokine production
-
DOI 10.1007/s00436-004-1285-3
-
Hernandez Mendoza L, Molinari JL, Garrido E, Cortes I, Solano S, Miranda E, Tato P: The implantation of Taenia solium metacestodes in mice induces downmodulation of T-cell proliferation and cytokine production. Parasitol Res 2005;95:256-265. (Pubitemid 40379466)
-
(2005)
Parasitology Research
, vol.95
, Issue.4
, pp. 256-265
-
-
Hernandez-Mendoza, L.1
Molinari, J.L.2
Garrido, E.3
Cortes, I.4
Solano, S.5
Miranda, E.6
Tato, P.7
-
22
-
-
23844524089
-
Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis
-
DOI 10.1038/nm1269
-
Jo D, Liu D, Yao S, Collins RD, Hawiger J: Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis. Nature Med 2005;11:892-898. (Pubitemid 41161123)
-
(2005)
Nature Medicine
, vol.11
, Issue.8
, pp. 892-898
-
-
Jo, D.1
Liu, D.2
Yao, S.3
Collins, R.D.4
Hawiger, J.5
-
23
-
-
0043136713
-
Nramp1 functionality increases inducible nitric oxide synthase transcription via stimulation of IFN regulatory factor 1 expression
-
Fritsche G, Dlaska M, Barton H, Theurl I, Garimorth K, Weiss G: Nramp1 functionality increases inducible nitric oxide synthase transcription via stimulation of IFN regulatory factor 1 expression. J Immunol 2003;171:1994-1998. (Pubitemid 36966483)
-
(2003)
Journal of Immunology
, vol.171
, Issue.4
, pp. 1994-1998
-
-
Fritsche, G.1
Dlaska, M.2
Barton, H.3
Theurl, I.4
Garimorth, K.5
Weiss, G.6
-
24
-
-
0028106830
-
Role of interferon regulatory factor 1 in induction of nitric oxide synthase
-
DOI 10.1084/jem.180.3.977
-
Martin E, Nathan C, Xie QW: Role of Interferon Regulatory Factor 1 in induction of Nitric Oxide Synthase. J Exp Med 1994;180:977-984. (Pubitemid 24256610)
-
(1994)
Journal of Experimental Medicine
, vol.180
, Issue.3
, pp. 977-984
-
-
Martin, E.1
Nathan, C.2
Xie, Q.-W.3
-
25
-
-
77954486084
-
Procarboxypeptidase R Deficiency Causes Increased Lethality in Concanavalin A-Induced Hepatitis in Female Mice
-
Asai S, Kimbara N, Tada T, Imai M, Campbell W, Okada H, Okada N: Procarboxypeptidase R Deficiency Causes Increased Lethality in Concanavalin A-Induced Hepatitis in Female Mice. Biol Pharm Bull 2010;33:1256-1259.
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 1256-1259
-
-
Asai, S.1
Kimbara, N.2
Tada, T.3
Imai, M.4
Campbell, W.5
Okada, H.6
Okada, N.7
-
26
-
-
79751536504
-
Inhibition of proinflammatory macrophage responses and lymphocyte proliferation in vitro by ethyl acetate leaf extract from Daphne gnidium
-
Harizi H, Chaabane F, Ghedira K, Chekir-Ghedira L: Inhibition of proinflammatory macrophage responses and lymphocyte proliferation in vitro by ethyl acetate leaf extract from Daphne gnidium Cell Immunol 2010;267:94-101
-
(2010)
Cell Immunol
, vol.267
, pp. 94-101
-
-
Harizi, H.1
Chaabane, F.2
Ghedira, K.3
Chekir-Ghedira, L.4
-
27
-
-
0031772126
-
The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release
-
Bradham CA, Qian T, Streetz K, Trautwein C, Brenner DA, JJ: The Mitochondrial Permeability Transition Is Required for Tumor Necrosis Factor Alpha-Mediated Apoptosis and Cytochrome c Release. Mol Cell Biol 1998;18:6353-6364. (Pubitemid 28500525)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.11
, pp. 6353-6364
-
-
Bradham, C.A.1
Qian, T.2
Streetz, K.3
Trautwein, C.4
Brenner, D.A.5
Lemasters, J.J.6
-
28
-
-
0034598156
-
Augmentation of Vα14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis
-
DOI 10.1084/jem.191.1.105
-
Kaneko Y, Harada M, Kawano T, Yamashita M, Shibata Y, Gejyo F, Nakayama T, Taniguchi M: Augmentation of V14 Nkt cell-mediated cytotoxicity by interleukin 4 in an autucrine mechanism resulting in the development of concanavalin a-induced hepatitis. J Exp Med 2000;191:105-114. (Pubitemid 30043652)
-
(2000)
Journal of Experimental Medicine
, vol.191
, Issue.1
, pp. 105-114
-
-
Kaneko, Y.1
Harada, M.2
Kawano, T.3
Yamashita, M.4
Shibata, Y.5
Gejyo, F.6
Nakayama, T.7
Taniguchi, M.8
-
29
-
-
0034746919
-
NF-βB: A key role in inflammatory diseases
-
Tak PP, Firestein GS: NF-βB: a key role in inflammatory diseases. J Clin Invest 2001;107:7.
-
(2001)
J Clin Invest
, vol.107
, pp. 7
-
-
Tak, P.P.1
Firestein, G.S.2
-
30
-
-
72549094548
-
A novel technique for selective NFkappaB inhibition in Kupffer cells: Contrary effects in fulminant hepatitis and ischaemia-reperfusion
-
Hoffmann F, Sass G, Zillies J, Zahler S, Tiegs G, Hartkorn A, Fuchs S, Wagner J, Winter G, Coester C, Gerbes AL, Vollmar AM: A novel technique for selective NFkappaB inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion. Gut 2009;58:1670-1678.
-
(2009)
Gut
, vol.58
, pp. 1670-1678
-
-
Hoffmann, F.1
Sass, G.2
Zillies, J.3
Zahler, S.4
Tiegs, G.5
Hartkorn, A.6
Fuchs, S.7
Wagner, J.8
Winter, G.9
Coester, C.10
Gerbes, A.L.11
Vollmar, A.M.12
-
31
-
-
13744255589
-
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
-
DOI 10.1172/JCI200522675
-
Duffield JS, Forbes SJ, Constandinou CM, Clay S, Partolina M, Vuthoori S, Wu S, Lang R, Iredale JP: Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Inves 2005;115:56-65. (Pubitemid 40385505)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.1
, pp. 56-65
-
-
Duffield, J.S.1
Forbes, S.J.2
Constandinou, C.M.3
Clay, S.4
Partolina, M.5
Vuthoori, S.6
Wu, S.7
Lang, R.8
Iredale, J.P.9
-
33
-
-
0034812914
-
Disrupted signaling and inhibited regeneration in obese mice with fatty livers: Implications for nonalcoholic fatty liver disease pathophysiology
-
DOI 10.1053/jhep.2001.28054
-
Yang SQ, Lin HZ, Mandal AK, Huang J, Diehl AM: Disrupted signaling and inhibited regeneration in obese mice with fatty livers: Implications for nonalcoholic fatty liver disease pathophysiology. Hepatology 2001;34:694-706. (Pubitemid 32927993)
-
(2001)
Hepatology
, vol.34
, Issue.4
, pp. 694-706
-
-
Yang, S.Q.1
Mandal, A.K.2
Huang, J.3
Diehl, A.M.4
-
34
-
-
33646751327
-
Evolution of the thienopyridine class of inhibitors of IβB kinase-β: Part I: Hit-to-lead strategies
-
Morwick T, Berry A, Brickwood J, Cardozo M, Catron K, DeTuri M, Emeigh J, Homon C, Hrapchak M, Jacober S, Jakes S, Kaplita P, Kelly TA, Ksiazek J, Liuzzi M, Magolda R, Mao C, Marshall D, McNeil D, Prokopowicz A, Sarko C, Scouten E, Sledziona C, Sun A, Watrous J, Wu JP, Cywin CL: Evolution of the Thienopyridine Class of Inhibitors of IβB Kinase-β: Part I: Hit-to-Lead Strategies. J Med Chem 2006;49:2898-2908.
-
(2006)
J Med Chem
, vol.49
, pp. 2898-2908
-
-
Morwick, T.1
Berry, A.2
Brickwood, J.3
Cardozo, M.4
Catron, K.5
Deturi, M.6
Emeigh, J.7
Homon, C.8
Hrapchak, M.9
Jacober, S.10
Jakes, S.11
Kaplita, P.12
Kelly, T.A.13
Ksiazek, J.14
Liuzzi, M.15
Magolda, R.16
Mao, C.17
Marshall, D.18
McNeil, D.19
Prokopowicz, A.20
Sarko, C.21
Scouten, E.22
Sledziona, C.23
Sun, A.24
Watrous, J.25
Wu, J.P.26
Cywin, C.L.27
more..
|