8,8-Dialkyldihydroberberines with potent antiprotozoal activity

Journal of Natural Products

Volumn 76, Issue 3, 2013, Pages 311-315

  Endeshaw, Molla ^a   Zhu, Xiaohua ^a   He, Shanshan ^a   Pandharkar, Trupti ^a   Cason, Emily ^b   Mahasenan, Kiran V ^a   Agarwal, Hitesh ^a   Li, Chenglong ^a   Munde, Manoj ^c   Wilson, W David ^c   Bahar, Mark ^a   Doskotch, Raymond W ^a   Kinghorn, A Douglas ^a   Kaiser, Marcel ^d,e   Brun, Reto ^d,e   Drew, Mark E ^a,b   Werbovetz, Karl A ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c GEORGIA STATE UNIVERSITY   (United States)

^d SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^e UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

8,8 DIETHYLDIHYDROBERBERINE; BERBERINE; BERBERINE DERIVATIVE; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; FEMALE; IN VITRO STUDY; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM FALCIPARUM; TRYPANOSOMA BRUCEI;

ANIMALS; ANTIMALARIALS; ANTIPROTOZOAL AGENTS; BERBERINE ALKALOIDS; CRYSTALLOGRAPHY, X-RAY; FEMALE; INHIBITORY CONCENTRATION 50; LEISHMANIA DONOVANI; MICE; MICE, INBRED BALB C; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; TRYPANOSOMA;

LEISHMANIA DONOVANI; MUS; PLASMODIUM FALCIPARUM; TRYPANOSOMA BRUCEI BRUCEI;

EID: 84875456778     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np300638f     Document Type: Article

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