Selective Antimicrotubule Activity of N1-Phenyl-3,5-dinitro-N4,N4-di-n-propylsulfanilamide (GB-II-5) against Kinetoplastid Parasites

Molecular Pharmacology

Volumn 64, Issue 6, 2003, Pages 1325-1333

  Werbovetz, Karl A ^a   Sackett, Dan L ^b   Delfín, Dawn ^a   Bhattacharya, Gautam ^a   Salem, Manar ^a   Obrzut, Tomasz ^b   Rattendi, Donna ^c   Bacchi, Cyrus ^c  

^a OHIO STATE UNIVERSITY   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c PACE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANSAMITOCIN P 3; ANTILEISHMANIAL AGENT; ANTIMITOTIC AGENT; ANTITRYPANOSOMAL AGENT; GB II 46; GB II 5; HERBICIDE; N1 PHENYL 3,5 DINITRO N4,N4 DI N PROPYLSULFANILAMIDE; ORYZALIN; PENTAMIDINE; SURAMIN; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN; CANCER CELL; CELL CYCLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SENSITIVITY; FLUORESCENCE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; KINETOPLAST; LEISHMANIA DONOVANI; MACROPHAGE; MAMMAL; MICROTUBULE; MOLECULE; NONHUMAN; PARASITE; PARASITE DEVELOPMENT; PRIORITY JOURNAL; PROMASTIGOTE; PROSTATE CANCER; PROTEIN ASSEMBLY; RAT; SWINE; TRYPANOSOMA BRUCEI;

ANIMALS; ANTIPROTOZOAL AGENTS; DINITROBENZENES; GROWTH INHIBITORS; HERBICIDES; KINETOPLASTIDA; LEISHMANIA DONOVANI; MICROTUBULES; RATS; SULFANILAMIDES; SWINE; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0346996811     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.6.1325     Document Type: Article

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