Computational, structural, and kinetic evidence that Vibrio vulnificus FrsA is not a cofactor-independent pyruvate decarboxylase

Biochemistry

Volumn 52, Issue 11, 2013, Pages 1842-1844

  Kellett, Whitney F ^a,e   Brunk, Elizabeth ^b   Desai, Bijoy J ^c   Fedorov, Alexander A ^d   Almo, Steven C ^d   Gerlt, John A ^c   Rothlisberger, Ursula ^b   Richards, Nigel G J ^a,e  

^a University of Florida   (United States)

^b EPFL   (Switzerland)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; C-C BOND CLEAVAGES; FUNCTIONAL ANNOTATION; KINETIC EVIDENCE; PYRUVATE DECARBOXYLASE; PYRUVATES; QUANTUM MECHANICAL; VIBRIO VULNIFICUS;

CARBOXYLATION; RECOMBINANT PROTEINS;

BACTERIA;

BACTERIAL PROTEIN; FRSA PROTEIN; HYDRONIUM ION; PYRUVATE DECARBOXYLASE; UNCLASSIFIED DRUG; WATER;

ARTICLE; COVALENT BOND; CRYSTAL STRUCTURE; DECARBOXYLATION; ENZYME ACTIVE SITE; HYDROGEN BOND; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PURIFICATION; PROTON TRANSPORT; VIBRIO VULNIFICUS;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DECARBOXYLATION; MODELS, MOLECULAR; PYRUVATE DECARBOXYLASE; PYRUVIC ACID; RECOMBINANT PROTEINS; VIBRIO VULNIFICUS;

VIBRIO VULNIFICUS;

EID: 84875453333     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400093y     Document Type: Article

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