-
1
-
-
84863625224
-
A CXCL1 paracrine network links cancerchemoresistance and metastasis
-
Acharyya S, Oskarsson T, Vanharanta S, Malladi S, Kim J, Morris PG, Manova-Todorova K, Leversha M, Hogg N, Seshan VE, Norton L, Brogi E, Massague J (2012) A CXCL1 paracrine network links cancerchemoresistance and metastasis. Cell 150 (1) : 165-178.
-
(2012)
Cell
, vol.150
, Issue.1
, pp. 165-178
-
-
Acharyya, S.1
Oskarsson, T.2
Vanharanta, S.3
Malladi, S.4
Kim, J.5
Morris, P.G.6
Manova-Todorova, K.7
Leversha, M.8
Hogg, N.9
Seshan, V.E.10
Norton, L.11
Brogi, E.12
Massague, J.13
-
2
-
-
82755194789
-
The chemokine system and cancer
-
Balkwill FR (2012) The chemokine system and cancer. J Pathol 226 (2) :148-157.
-
(2012)
J Pathol
, vol.226
, Issue.2
, pp. 148-157
-
-
Balkwill, F.R.1
-
3
-
-
84872065981
-
Oncogenictranscription factors: Cornerstones of inflammation-linked pancreaticcarcinogenesis
-
Baumgart S, Ellenrieder V, Fernandez-Zapico ME (2011) Oncogenictranscription factors: cornerstones of inflammation-linked pancreaticcarcinogenesis. Gut 62 (2) : 310-316.
-
(2011)
Gut
, vol.62
, Issue.2
, pp. 310-316
-
-
Baumgart, S.1
Ellenrieder, V.2
Fernandez-Zapico, M.E.3
-
4
-
-
84862150896
-
Tumor-derived granulocyte-macrophage colony-stimulatingfactor regulates myeloid inflammation and T cell immunity in pancreaticcancer
-
Bayne LJ, Beatty GL, Jhala N, Clark CE, Rhim AD, Stanger BZ, VonderheideRH (2012) Tumor-derived granulocyte-macrophage colony- stimulatingfactor regulates myeloid inflammation and T cell immunity in pancreaticcancer. Cancer Cell 21 (6) : 822-835.
-
(2012)
Cancer Cell
, vol.21
, Issue.6
, pp. 822-835
-
-
Bayne, L.J.1
Beatty, G.L.2
Jhala, N.3
Clark, C.E.4
Rhim, A.D.5
Stanger, B.Z.6
Vonderheide, R.H.7
-
5
-
-
79953154967
-
CD40 agonists alter tumor stroma and showefficacy against pancreatic carcinoma in mice and humans
-
Beatty GL, Chiorean EG, Fishman MP, Saboury B, Teitelbaum UR, Sun W, Huhn RD, Song W, Li D, Sharp LL, Torigian DA, O'Dwyer PJ, Vonderheide RH (2011) CD40 agonists alter tumor stroma and showefficacy against pancreatic carcinoma in mice and humans. Science331 (6024) : 1612-1616.
-
(2011)
Science
, vol.331
, Issue.6024
, pp. 1612-1616
-
-
Beatty, G.L.1
Chiorean, E.G.2
Fishman, M.P.3
Saboury, B.4
Teitelbaum, U.R.5
Sun, W.6
Huhn, R.D.7
Song, W.8
Li, D.9
Sharp, L.L.10
Torigian, D.A.11
O'Dwyer, P.J.12
Vonderheide, R.H.13
-
6
-
-
78650582001
-
Current status ofmolecular markers for early detection of sporadic pancreatic cancer
-
Chakraborty S, Baine MJ, Sasson AR, Batra SK (2011) Current status ofmolecular markers for early detection of sporadic pancreatic cancer.Biochim Biophys Acta 1815 (1) : 44-64.
-
(2011)
Biochim Biophys Acta
, vol.1815
, Issue.1
, pp. 44-64
-
-
Chakraborty, S.1
Baine, M.J.2
Sasson, A.R.3
Batra, S.K.4
-
7
-
-
35148814410
-
Dynamics of the immune reaction to pancreatic cancer frominception to invasion
-
Clark CE, Hingorani SR, Mick R, Combs C, Tuveson DA, Vonderheide RH (2007) Dynamics of the immune reaction to pancreatic cancer frominception to invasion. Cancer Res 67 (19) : 9518-9527.
-
(2007)
Cancer Res
, vol.67
, Issue.19
, pp. 9518-9527
-
-
Clark, C.E.1
Hingorani, S.R.2
Mick, R.3
Combs, C.4
Tuveson, D.A.5
Vonderheide, R.H.6
-
8
-
-
79960383874
-
STAT3 plays acritical role in KRAS-induced pancreatic tumorigenesis
-
Corcoran RB, Contino G, Deshpande V, Tzatsos A, Conrad C, Benes CH, Levy DE, Settleman J, Engelman JA, Bardeesy N (2011) STAT3 plays acritical role in KRAS-induced pancreatic tumorigenesis. Cancer Res71 (14) : 5020-5029.
-
(2011)
Cancer Res
, vol.71
, Issue.14
, pp. 5020-5029
-
-
Corcoran, R.B.1
Contino, G.2
Deshpande, V.3
Tzatsos, A.4
Conrad, C.5
Benes, C.H.6
Levy, D.E.7
Settleman, J.8
Engelman, J.A.9
Bardeesy, N.10
-
9
-
-
79960060305
-
Oncogene-induced Nrf2 transcription promotes ROS detoxification andtumorigenesis
-
DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, Mangal D, Yu KH, Yeo CJ, Calhoun ES, Scrimieri F, Winter JM, HrubanRH, Iacobuzio-Donahue C, Kern SE, Blair IA, Tuveson DA (2011) Oncogene-induced Nrf2 transcription promotes ROS detoxification andtumorigenesis. Nature 475 (7354) : 106-109.
-
(2011)
Nature
, vol.475
, Issue.7354
, pp. 106-109
-
-
Denicola, G.M.1
Karreth, F.A.2
Humpton, T.J.3
Gopinathan, A.4
Wei, C.5
Frese, K.6
Mangal, D.7
Yu, K.H.8
Yeo, C.J.9
Calhoun, E.S.10
Scrimieri, F.11
Winter, J.M.12
Hruban, R.H.13
Iacobuzio-Donahue, C.14
Kern, S.E.15
Blair, I.A.16
Tuveson, D.A.17
-
10
-
-
80051734669
-
Features associated with survival in metastatic melanoma patientstreated with patient-specific dendritic cell vaccines
-
Dillman RO, Fogel GB, Cornforth AN, Selvan SR, Schiltz PM, DePriest C (2011) Features associated with survival in metastatic melanoma patientstreated with patient-specific dendritic cell vaccines. Cancer BiotherRadiopharm 26 (4) : 407-415.
-
(2011)
Cancer BiotherRadiopharm
, vol.26
, Issue.4
, pp. 407-415
-
-
Dillman, R.O.1
Fogel, G.B.2
Cornforth, A.N.3
Selvan, S.R.4
Schiltz, P.M.5
Depriest, C.6
-
11
-
-
40449090323
-
Anti-tumor necrosis factor therapy inhibits pancreatictumor growth and metastasis
-
Egberts JH, Cloosters V, Noack A, Schniewind B, Thon L, Klose S, Kettler B, von Forstner C, Kneitz C, Tepel J, Adam D, Wajant H, Kalthoff H, Trauzold A (2008) Anti-tumor necrosis factor therapy inhibits pancreatictumor growth and metastasis. Cancer Res 68 (5) : 1443-1450.
-
(2008)
Cancer Res
, vol.68
, Issue.5
, pp. 1443-1450
-
-
Egberts, J.H.1
Cloosters, V.2
Noack, A.3
Schniewind, B.4
Thon, L.5
Klose, S.6
Kettler, B.7
Von Forstner, C.8
Kneitz, C.9
Tepel, J.10
Adam, D.11
Wajant, H.12
Kalthoff, H.13
Trauzold, A.14
-
12
-
-
31544467315
-
A phase II study of celecoxib, gemcitabine, and cisplatin in advancedpancreatic cancer
-
El-Rayes BF, Zalupski MM, Shields AF, Ferris AM, Vaishampayan U, Heilbrun LK, Venkatramanamoorthy R, Adsay V, Philip PA (2005) A phase II study of celecoxib, gemcitabine, and cisplatin in advancedpancreatic cancer. Invest New Drugs 23 (6) : 583-590.
-
(2005)
Invest New Drugs
, vol.23
, Issue.6
, pp. 583-590
-
-
El-Rayes, B.F.1
Zalupski, M.M.2
Shields, A.F.3
Ferris, A.M.4
Vaishampayan, U.5
Heilbrun, L.K.6
Venkatramanamoorthy, R.7
Adsay, V.8
Philip, P.A.9
-
13
-
-
2442689246
-
Inflammatory mechanisms contributing to pancreatic cancerdevelopment
-
discussion 769-771
-
Farrow B, Sugiyama Y, Chen A, Uffort E, Nealon W, Mark Evers B (2004) Inflammatory mechanisms contributing to pancreatic cancerdevelopment. Ann Surg 239 (6) : 763-769discussion 769-771.
-
(2004)
Ann Surg
, vol.239
, Issue.6
, pp. 763-769
-
-
Farrow, B.1
Sugiyama, Y.2
Chen, A.3
Uffort, E.4
Nealon, W.5
Mark Evers, B.6
-
14
-
-
45549092607
-
Cancer immunology
-
Finn OJ (2008) Cancer immunology. N Engl J Med 358 (25) : 2704-2715.
-
(2008)
N Engl J Med
, vol.358
, Issue.25
, pp. 2704-2715
-
-
Finn, O.J.1
-
15
-
-
84863849090
-
Nab-Paclitaxel potentiates gemcitabine activity by reducingcytidine deaminase levels in a mouse model of pancreatic cancer
-
Frese KK, Neesse A, Cook N, Bapiro TE, Lolkema MP, Jodrell DI, TuvesonDA (2012) nab-Paclitaxel potentiates gemcitabine activity by reducingcytidine deaminase levels in a mouse model of pancreatic cancer. CancerDiscov 2 (3) : 260-269.
-
(2012)
CancerDiscov
, vol.2
, Issue.3
, pp. 260-269
-
-
Frese, K.K.1
Neesse, A.2
Cook, N.3
Bapiro, T.E.4
Lolkema, M.P.5
Jodrell, D.I.6
Tuveson, D.A.7
-
16
-
-
69249222379
-
Polarization of tumor-associated neutrophil phenotypeby TGF-beta: 'N1' versus 'N2' TAN
-
Fridlender ZG, Sun J, Kim S, Kapoor V, Cheng G, Ling L, Worthen GS, Albelda SM (2009) Polarization of tumor-associated neutrophil phenotypeby TGF-beta: 'N1' versus 'N2' TAN. Cancer Cell 16 (3) : 183-194.
-
(2009)
Cancer Cell
, vol.16
, Issue.3
, pp. 183-194
-
-
Fridlender, Z.G.1
Sun, J.2
Kim, S.3
Kapoor, V.4
Cheng, G.5
Ling, L.6
Worthen, G.S.7
Albelda, S.M.8
-
17
-
-
79953761842
-
Stat3 and MMP7contribute to pancreatic ductal adenocarcinoma initiation andprogression
-
Fukuda A, Wang SC, Morris JPt, Folias AE, Liou A, Kim GE, Akira S, BoucherKM, Firpo MA, Mulvihill SJ, Hebrok M (2011) Stat3 and MMP7contribute to pancreatic ductal adenocarcinoma initiation andprogression. Cancer Cell 19 (4) : 441-455.
-
(2011)
Cancer Cell
, vol.19
, Issue.4
, pp. 441-455
-
-
Fukuda, A.1
Wang, S.C.2
Jpt, M.3
Folias, A.E.4
Liou, A.5
Kim, G.E.6
Akira, S.7
Boucher, K.M.8
Firpo, M.A.9
Mulvihill, S.J.10
Hebrok, M.11
-
18
-
-
34547613903
-
Delayed progression of pancreatic intraepithelial neoplasia in aconditional Kras (G12D) mouse model by a selective cyclooxygenase-2inhibitor
-
Funahashi H, Satake M, Dawson D, Huynh NA, Reber HA, Hines OJ, Eibl G (2007) Delayed progression of pancreatic intraepithelial neoplasia in aconditional Kras (G12D) mouse model by a selective cyclooxygenase-2inhibitor. Cancer Res 67 (15) : 7068-7071.
-
(2007)
Cancer Res
, vol.67
, Issue.15
, pp. 7068-7071
-
-
Funahashi, H.1
Satake, M.2
Dawson, D.3
Huynh, N.A.4
Reber, H.A.5
Hines, O.J.6
Eibl, G.7
-
19
-
-
61349100687
-
Myeloid-derived suppressorcells as regulators of the immune system
-
Gabrilovich DI, Nagaraj S (2009) Myeloid-derived suppressorcells as regulators of the immune system. Nat Rev Immunol 9 (3) :162-174.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.3
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
20
-
-
33847419143
-
Chronicpancreatitis is essential for induction of pancreatic ductal adenocarcinomaby K-Ras oncogenes in adult mice
-
Guerra C, Schuhmacher AJ, Canamero M, Grippo PJ, Verdaguer L, Perez-Gallego L, Dubus P, Sandgren EP, Barbacid M (2007) Chronicpancreatitis is essential for induction of pancreatic ductal adenocarcinomaby K-Ras oncogenes in adult mice. Cancer Cell 11 (3) : 291-302.
-
(2007)
Cancer Cell
, vol.11
, Issue.3
, pp. 291-302
-
-
Guerra, C.1
Schuhmacher, A.J.2
Canamero, M.3
Grippo, P.J.4
Verdaguer, L.5
Perez-Gallego, L.6
Dubus, P.7
Sandgren, E.P.8
Barbacid, M.9
-
21
-
-
45149134605
-
'Re-educating' tumor-associatedmacrophages by targeting NF-kappaB
-
Hagemann T, Lawrence T, McNeish I, Charles KA, Kulbe H, Thompson RG, Robinson SC, Balkwill FR (2008) 'Re-educating' tumor-associatedmacrophages by targeting NF-kappaB. J Exp Med 205 (6) : 1261-1268.
-
(2008)
J Exp Med
, vol.205
, Issue.6
, pp. 1261-1268
-
-
Hagemann, T.1
Lawrence, T.2
McNeish, I.3
Charles, K.A.4
Kulbe, H.5
Thompson, R.G.6
Robinson, S.C.7
Balkwill, F.R.8
-
22
-
-
33646577163
-
Genetics and biology of pancreatic ductal adenocarcinoma
-
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA (2006) Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev20 (10) : 1218-1249.
-
(2006)
Genes Dev
, vol.20
, Issue.10
, pp. 1218-1249
-
-
Hezel, A.F.1
Kimmelman, A.C.2
Stanger, B.Z.3
Bardeesy, N.4
Depinho, R.A.5
-
23
-
-
78650508742
-
CXCL17 and ICAM2 are associated with a potential antitumorimmune response in early intraepithelial stages of humanpancreatic carcinogenesis
-
Hiraoka N, Yamazaki-Itoh R, Ino Y, Mizuguchi Y, Yamada T, Hirohashi S, Kanai Y (2011) CXCL17 and ICAM2 are associated with a potential antitumorimmune response in early intraepithelial stages of humanpancreatic carcinogenesis. Gastroenterology 140 (1) : 310-321.
-
(2011)
Gastroenterology
, vol.140
, Issue.1
, pp. 310-321
-
-
Hiraoka, N.1
Yamazaki-Itoh, R.2
Ino, Y.3
Mizuguchi, Y.4
Yamada, T.5
Hirohashi, S.6
Kanai, Y.7
-
24
-
-
0033887693
-
Progression model forpancreatic cancer
-
Hruban RH, Goggins M, Parsons J, Kern SE (2000) Progression model forpancreatic cancer. Clin Cancer Res 6 (8) : 2969-2972.
-
(2000)
Clin Cancer Res
, vol.6
, Issue.8
, pp. 2969-2972
-
-
Hruban, R.H.1
Goggins, M.2
Parsons, J.3
Kern, S.E.4
-
25
-
-
80053405625
-
Inhibiting Cxcr2 disrupts tumorstromalinteractions and improves survival in a mouse model of pancreaticductal adenocarcinoma
-
Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, Moses HL (2011) Inhibiting Cxcr2 disrupts tumorstromalinteractions and improves survival in a mouse model of pancreaticductal adenocarcinoma. J Clin Invest 121 (10) : 4106-4117.
-
(2011)
J Clin Invest
, vol.121
, Issue.10
, pp. 4106-4117
-
-
Ijichi, H.1
Chytil, A.2
Gorska, A.E.3
Aakre, M.E.4
Bierie, B.5
Tada, M.6
Mohri, D.7
Miyabayashi, K.8
Asaoka, Y.9
Maeda, S.10
Ikenoue, T.11
Tateishi, K.12
Wright, C.V.13
Koike, K.14
Omata, M.15
Moses, H.L.16
-
26
-
-
33846916208
-
Peritumoral fibroblast SPARCexpression and patient outcome with resectable pancreaticadenocarcinoma
-
Infante JR, Matsubayashi H, Sato N, Tonascia J, Klein AP, Riall TA, Yeo C, Iacobuzio-Donahue C, Goggins M (2007) Peritumoral fibroblast SPARCexpression and patient outcome with resectable pancreaticadenocarcinoma. J Clin Oncol 25 (3) : 319-325.
-
(2007)
J Clin Oncol
, vol.25
, Issue.3
, pp. 319-325
-
-
Infante, J.R.1
Matsubayashi, H.2
Sato, N.3
Tonascia, J.4
Klein, A.P.5
Riall, T.A.6
Yeo, C.7
Iacobuzio-Donahue, C.8
Goggins, M.9
-
27
-
-
84871157346
-
Hyaluronan impairs vascular function and drugdelivery in a mouse model of pancreatic cancer
-
Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, Feig C, Nakagawa T, Caldwell ME, Zecchini HI, Lolkema MP, Jiang P, Kultti A, Thompson CB, Maneval DC, Jodrell DI, Frost GI, Shepard HM, SkepperJN, Tuveson DA (2012) Hyaluronan impairs vascular function and drugdelivery in a mouse model of pancreatic cancer. Gut 62 (1) : 112-120.
-
(2012)
Gut
, vol.62
, Issue.1
, pp. 112-120
-
-
Jacobetz, M.A.1
Chan, D.S.2
Neesse, A.3
Bapiro, T.E.4
Cook, N.5
Frese, K.K.6
Feig, C.7
Nakagawa, T.8
Caldwell, M.E.9
Zecchini, H.I.10
Lolkema, M.P.11
Jiang, P.12
Kultti, A.13
Thompson, C.B.14
Maneval, D.C.15
Jodrell, D.I.16
Frost, G.I.17
Shepard, H.M.18
Skepper, J.N.19
Tuveson, D.A.20
more..
-
28
-
-
34248345864
-
Chronic pancreatitis, pseudotumors and other tumor-likelesions
-
Kloppel G (2007) Chronic pancreatitis, pseudotumors and other tumor-likelesions. Mod Pathol 20 (Suppl 1) : S113-S131.
-
(2007)
Mod Pathol
, vol.20
, Issue.SUPPL. 1
-
-
Kloppel, G.1
-
29
-
-
78650755741
-
Regulation of tumor immunityby tumor/dendritic cell fusions
-
Koido S, Homma S, Hara E, Namiki Y, Takahara A, Komita H, Nagasaki E, Ito M, Ohkusa T, Gong J, Tajiri H (2010) Regulation of tumor immunityby tumor/dendritic cell fusions. Clin Dev Immunol 2010: 516768.
-
(2010)
Clin Dev Immunol
, vol.2010
, pp. 516768
-
-
Koido, S.1
Homma, S.2
Hara, E.3
Namiki, Y.4
Takahara, A.5
Komita, H.6
Nagasaki, E.7
Ito, M.8
Ohkusa, T.9
Gong, J.10
Tajiri, H.11
-
30
-
-
25444456369
-
Tumor-associated CD8\+T cell tolerance induced by bone marrow-derived immature myeloid cells
-
Kusmartsev S, Nagaraj S, Gabrilovich DI (2005) Tumor-associated CD8\+T cell tolerance induced by bone marrow-derived immature myeloid cells.J Immunol 175 (7) : 4583-4592.
-
(2005)
J Immunol
, vol.175
, Issue.7
, pp. 4583-4592
-
-
Kusmartsev, S.1
Nagaraj, S.2
Gabrilovich, D.I.3
-
31
-
-
78249289929
-
Oncogenic KRas suppresses inflammationassociatedsenescence of pancreatic ductal cells
-
Lee KE, Bar-Sagi D (2010) Oncogenic KRas suppresses inflammationassociatedsenescence of pancreatic ductal cells. Cancer Cell 18 (5) :448-458.
-
(2010)
Cancer Cell
, vol.18
, Issue.5
, pp. 448-458
-
-
Lee, K.E.1
Bar-Sagi, D.2
-
32
-
-
79953756112
-
Stat3/Socs3 activation by IL-6 transsignaling promotes progression ofpancreatic intraepithelial neoplasia and development of pancreatic cancer
-
Lesina M, Kurkowski MU, Ludes K, Rose-John S, Treiber M, Kloppel G, Yoshimura A, Reindl W, Sipos B, Akira S, Schmid RM, Algul H (2011) Stat3/Socs3 activation by IL-6 transsignaling promotes progression ofpancreatic intraepithelial neoplasia and development of pancreatic cancer.Cancer Cell 19 (4) : 456-469.
-
(2011)
Cancer Cell
, vol.19
, Issue.4
, pp. 456-469
-
-
Lesina, M.1
Kurkowski, M.U.2
Ludes, K.3
Rose-John, S.4
Treiber, M.5
Kloppel, G.6
Yoshimura, A.7
Reindl, W.8
Sipos, B.9
Akira, S.10
Schmid, R.M.11
Algul, H.12
-
33
-
-
79952752362
-
Overexpression of CXCL5 is associated with poor survival in patients withpancreatic cancer
-
Li A, King J, Moro A, Sugi MD, Dawson DW, Kaplan J, Li G, Lu X, StrieterRM, Burdick M, Go VL, Reber HA, Eibl G, Hines OJ (2011) Overexpression of CXCL5 is associated with poor survival in patients withpancreatic cancer. Am J Pathol 178 (3) : 1340-1349.
-
(2011)
Am J Pathol
, vol.178
, Issue.3
, pp. 1340-1349
-
-
Li, A.1
King, J.2
Moro, A.3
Sugi, M.D.4
Dawson, D.W.5
Kaplan, J.6
Li, G.7
Lu, X.8
Strieter, R.M.9
Burdick, M.10
Go, V.L.11
Reber, H.A.12
Eibl, G.13
Hines, O.J.14
-
34
-
-
78649248267
-
Synthetic triterpenoids prolong survival in a transgenic mousemodel of pancreatic cancer
-
Liby KT, Royce DB, Risingsong R, Williams CR, Maitra A, Hruban RH, SpornMB (2010) Synthetic triterpenoids prolong survival in a transgenic mousemodel of pancreatic cancer. Cancer Prev Res (Phila) 3 (11) : 1427-1434.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, Issue.11
, pp. 1427-1434
-
-
Liby, K.T.1
Royce, D.B.2
Risingsong, R.3
Williams, C.R.4
Maitra, A.5
Hruban, R.H.6
Sporn, M.B.7
-
35
-
-
84855946746
-
Kras G12D-induced IKK2/B/NFkB activation by IL-1alphaand p62 feedforward loops is requied for pancreatic ductaladenocarcinoma
-
Ling Jea (2012) Kras G12D-induced IKK2/B/NFkB activation by IL-1alphaand p62 feedforward loops is requied for pancreatic ductaladenocarcinoma. Cancer Cell 21: 105-120.
-
(2012)
Cancer Cell
, vol.21
, pp. 105-120
-
-
Ling, J.1
-
37
-
-
0027294719
-
Pancreatitis and the risk of pancreatic cancer. International PancreatitisStudy Group
-
Lowenfels AB, Maisonneuve P, Cavallini G, Ammann RW, Lankisch PG, Andersen JR, Dimagno EP, Andren-Sandberg A, Domellof L (1993) Pancreatitis and the risk of pancreatic cancer. International PancreatitisStudy Group. N Engl J Med 328 (20) : 1433-1437.
-
(1993)
N Engl J Med
, vol.328
, Issue.20
, pp. 1433-1437
-
-
Lowenfels, A.B.1
Maisonneuve, P.2
Cavallini, G.3
Ammann, R.W.4
Lankisch, P.G.5
Andersen, J.R.6
Dimagno, E.P.7
Andren-Sandberg, A.8
Domellof, L.9
-
38
-
-
66349109431
-
Secreted interleukin-1alpha induces a metastatic phenotype inpancreatic cancer by sustaining a constitutive activation of nuclear factorkappaB
-
Melisi D, Niu J, Chang Z, Xia Q, Peng B, Ishiyama S, Evans DB, Chiao PJ (2009) Secreted interleukin-1alpha induces a metastatic phenotype inpancreatic cancer by sustaining a constitutive activation of nuclear factorkappaB.Mol Cancer Res 7 (5) : 624-633.
-
(2009)
Mol Cancer Res
, vol.7
, Issue.5
, pp. 624-633
-
-
Melisi, D.1
Niu, J.2
Chang, Z.3
Xia, Q.4
Peng, B.5
Ishiyama, S.6
Evans, D.B.7
Chiao, P.J.8
-
39
-
-
79955828776
-
Stromal biologyand therapy in pancreatic cancer
-
Neesse A, Michl P, Frese KK, Feig C, Cook N, Jacobetz MA, Lolkema MP, Buchholz M, Olive KP, Gress TM, Tuveson DA (2011) Stromal biologyand therapy in pancreatic cancer. Gut 60 (6) : 861-868.
-
(2011)
Gut
, vol.60
, Issue.6
, pp. 861-868
-
-
Neesse, A.1
Michl, P.2
Frese, K.K.3
Feig, C.4
Cook, N.5
Jacobetz, M.A.6
Lolkema, M.P.7
Buchholz, M.8
Olive, K.P.9
Gress, T.M.10
Tuveson, D.A.11
-
40
-
-
77956416112
-
Adjuvant chemotherapy withfluorouracil plus folinic acid vs gemcitabine following pancreatic cancerresection: A randomized controlled trial
-
Neoptolemos JP, Stocken DD, Bassi C, Ghaneh P, Cunningham D, GoldsteinD, Padbury R, Moore MJ, Gallinger S, Mariette C, Wente MN, Izbicki JR, Friess H, Lerch MM, Dervenis C, Olah A, Butturini G, Doi R, Lind PA, Smith D, Valle JW, Palmer DH, Buckels JA, Thompson J, McKay CJ, Rawcliffe CL, Buchler MW (2010) Adjuvant chemotherapy withfluorouracil plus folinic acid vs gemcitabine following pancreatic cancerresection: a randomized controlled trial. JAMA 304 (10) : 1073-1081.
-
(2010)
JAMA
, vol.304
, Issue.10
, pp. 1073-1081
-
-
Neoptolemos, J.P.1
Stocken, D.D.2
Bassi, C.3
Ghaneh, P.4
Cunningham, D.5
Goldstein, D.6
Padbury, R.7
Moore, M.J.8
Gallinger, S.9
Mariette, C.10
Wente, M.N.11
Izbicki, J.R.12
Friess, H.13
Lerch, M.M.14
Dervenis, C.15
Olah, A.16
Butturini, G.17
Doi, R.18
Lind, P.A.19
Smith, D.20
Valle, J.W.21
Palmer, D.H.22
Buckels, J.A.23
Thompson, J.24
McKay, C.J.25
Rawcliffe, C.L.26
Buchler, M.W.27
more..
-
41
-
-
84868627145
-
Toll-like receptor 7regulates pancreatic carcinogenesis in mice and humans
-
Ochi A, Graffeo CS, Zambirinis CP, Rehman A, Hackman M, Fallon N, BarillaRM, Henning JR, Jamal M, Rao R, Greco S, Deutsch M, Medina-Zea MV, Saeed UB, Ego-Osuala MO, Hajdu C, Miller G (2012) Toll-like receptor 7regulates pancreatic carcinogenesis in mice and humans. J Clin Invest122 (11) : 4118-4129.
-
(2012)
J Clin Invest
, vol.122
, Issue.11
, pp. 4118-4129
-
-
Ochi, A.1
Graffeo, C.S.2
Zambirinis, C.P.3
Rehman, A.4
Hackman, M.5
Fallon, N.6
Barilla, R.M.7
Henning, J.R.8
Jamal, M.9
Rao, R.10
Greco, S.11
Deutsch, M.12
Medina-Zea, M.V.13
Saeed, U.B.14
Ego-Osuala, M.O.15
Hajdu, C.16
Miller, G.17
-
42
-
-
84866372497
-
MyD88 inhibition amplifiesdendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells
-
Ochi A, Nguyen AH, Bedrosian AS, Mushlin HM, Zarbakhsh S, Barilla R, Zambirinis CP, Fallon NC, Rehman A, Pylayeva-Gupta Y, Badar S, HajduCH, Frey AB, Bar-Sagi D, Miller G (2012) MyD88 inhibition amplifiesdendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells.J Exp Med 209 (9) : 1671-1687.
-
(2012)
J Exp Med
, vol.209
, Issue.9
, pp. 1671-1687
-
-
Ochi, A.1
Nguyen, A.H.2
Bedrosian, A.S.3
Mushlin, H.M.4
Zarbakhsh, S.5
Barilla, R.6
Zambirinis, C.P.7
Fallon, N.C.8
Rehman, A.9
Pylayeva-Gupta, Y.10
Badar, S.11
Hajdu, C.H.12
Frey, A.B.13
Bar-Sagi, D.14
Miller, G.15
-
43
-
-
67149143399
-
Inhibition of Hedgehog signalingenhances delivery of chemotherapy in a mouse model of pancreaticcancer
-
Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, Madhu B, Goldgraben MA, Caldwell ME, Allard D, Frese KK, Denicola G, Feig C, Combs C, Winter SP, Ireland-Zecchini H, Reichelt S, Howat WJ, Chang A, Dhara M, Wang L, Ruckert F, Grutzmann R, Pilarsky C, Izeradjene K, Hingorani SR, Huang P, Davies SE, Plunkett W, Egorin M, Hruban RH, Whitebread N, McGovern K, Adams J, Iacobuzio-DonahueC, Griffiths J, Tuveson DA (2009) Inhibition of Hedgehog signalingenhances delivery of chemotherapy in a mouse model of pancreaticcancer. Science 324 (5933) : 1457-1461.
-
(2009)
Science
, vol.324
, Issue.5933
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
McIntyre, D.5
Honess, D.6
Madhu, B.7
Goldgraben, M.A.8
Caldwell, M.E.9
Allard, D.10
Frese, K.K.11
Denicola, G.12
Feig, C.13
Combs, C.14
Winter, S.P.15
Ireland-Zecchini, H.16
Reichelt, S.17
Howat, W.J.18
Chang, A.19
Dhara, M.20
Wang, L.21
Ruckert, F.22
Grutzmann, R.23
Pilarsky, C.24
Izeradjene, K.25
Hingorani, S.R.26
Huang, P.27
Davies, S.E.28
Plunkett, W.29
Egorin, M.30
Hruban, R.H.31
Whitebread, N.32
McGovern, K.33
Adams, J.34
Iacobuzio-Donahue, C.35
Griffiths, J.36
Tuveson, D.A.37
more..
-
44
-
-
84858602107
-
Enzymatic targeting of the stroma ablates physical barriers totreatment of pancreatic ductal adenocarcinoma
-
Provenzano PP, Cuevas C, Chang AE, Goel VK, Von Hoff DD, Hingorani SR (2012) Enzymatic targeting of the stroma ablates physical barriers totreatment of pancreatic ductal adenocarcinoma. Cancer Cell 21 (3) :418-429.
-
(2012)
Cancer Cell
, vol.21
, Issue.3
, pp. 418-429
-
-
Provenzano, P.P.1
Cuevas, C.2
Chang, A.E.3
Goel, V.K.4
Von Hoff, D.D.5
Hingorani, S.R.6
-
45
-
-
84862147254
-
OncogenicKras-induced GM-CSF production promotes the development ofpancreatic neoplasia
-
Pylayeva-Gupta Y, Lee KE, Hajdu CH, Miller G, Bar-Sagi D (2012) OncogenicKras-induced GM-CSF production promotes the development ofpancreatic neoplasia. Cancer Cell 21 (6) : 836-847.
-
(2012)
Cancer Cell
, vol.21
, Issue.6
, pp. 836-847
-
-
Pylayeva-Gupta, Y.1
Lee, K.E.2
Hajdu, C.H.3
Miller, G.4
Bar-Sagi, D.5
-
46
-
-
84856088337
-
EMT and dissemination precede pancreatic tumor formation
-
Rhim AD, Mirek ET, Aiello NM, Maitra A, Bailey JM, McAllister F, ReichertM, Beatty GL, Rustgi AK, Vonderheide RH, Leach SD, Stanger BZ (2012) EMT and dissemination precede pancreatic tumor formation. Cell148 (1-2) : 349-361.
-
(2012)
Cell
, vol.148
, Issue.1-2
, pp. 349-361
-
-
Rhim, A.D.1
Mirek, E.T.2
Aiello, N.M.3
Maitra, A.4
Bailey, J.M.5
McAllister, F.6
Reichert, M.7
Beatty, G.L.8
Rustgi, A.K.9
Vonderheide, R.H.10
Leach, S.D.11
Stanger, B.Z.12
-
47
-
-
12644290242
-
Analysis of K-rasoncogene mutations in chronic pancreatitis with ductal hyperplasia
-
Rivera JA, Rall CJ, Graeme-Cook F, Fernandez-del Castillo C, Shu P, Lakey N, Tepper R, Rattner DW, Warshaw AL, Rustgi AK (1997) Analysis of K-rasoncogene mutations in chronic pancreatitis with ductal hyperplasia.Surgery 121 (1) : 42-49.
-
(1997)
Surgery
, vol.121
, Issue.1
, pp. 42-49
-
-
Rivera, J.A.1
Rall, C.J.2
Graeme-Cook, F.3
Fernandez-Del Castillo, C.4
Shu, P.5
Lakey, N.6
Tepper, R.7
Rattner, D.W.8
Warshaw, A.L.9
Rustgi, A.K.10
-
48
-
-
14444284330
-
Tumor-suppressive pathways in pancreatic carcinoma
-
Rozenblum E, Schutte M, Goggins M, Hahn SA, Panzer S, Zahurak M, Goodman SN, Sohn TA, Hruban RH, Yeo CJ, Kern SE (1997) Tumor-suppressive pathways in pancreatic carcinoma. Cancer Res57 (9) : 1731-1734.
-
(1997)
Cancer Res
, vol.57
, Issue.9
, pp. 1731-1734
-
-
Rozenblum, E.1
Schutte, M.2
Goggins, M.3
Hahn, S.A.4
Panzer, S.5
Zahurak, M.6
Goodman, S.N.7
Sohn, T.A.8
Hruban, R.H.9
Yeo, C.J.10
Kern, S.E.11
-
49
-
-
0032985541
-
Pancreatic cancer: Areport of treatment and survival trends for 100, 313 patients diagnosedfrom 1985-1995, using the National Cancer Database
-
Sener SF, Fremgen A, Menck HR, Winchester DP (1999) Pancreatic cancer: areport of treatment and survival trends for 100, 313 patients diagnosedfrom 1985-1995, using the National Cancer Database. J Am Coll Surg189 (1) : 1-7.
-
(1999)
J Am Coll Surg
, vol.189
, Issue.1
, pp. 1-7
-
-
Sener, S.F.1
Fremgen, A.2
Menck, H.R.3
Winchester, D.P.4
-
50
-
-
84857883847
-
Macrophage plasticity and polarization: In vivoveritas
-
Sica A, Mantovani A (2012) Macrophage plasticity and polarization: in vivoveritas. J Clin Invest 122 (3) : 787-795.
-
(2012)
J Clin Invest
, vol.122
, Issue.3
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
51
-
-
81555195411
-
Aspirin, nonsteroidal anti-inflammatory drugs, acetaminophen, and pancreatic cancer risk: A clinic-based case-controlstudy
-
Tan XL, Reid Lombardo KM, Bamlet WR, Oberg AL, Robinson DP, AndersonKE, Petersen GM (2011) Aspirin, nonsteroidal anti-inflammatory drugs, acetaminophen, and pancreatic cancer risk: a clinic-based case-controlstudy. Cancer Prev Res (Phila) 4 (11) : 1835-1841.
-
(2011)
Cancer Prev Res (Phila)
, vol.4
, Issue.11
, pp. 1835-1841
-
-
Tan, X.L.1
Reid Lombardo, K.M.2
Bamlet, W.R.3
Oberg, A.L.4
Robinson, D.P.5
Anderson, K.E.6
Petersen, G.M.7
-
52
-
-
84856103211
-
Understanding metastasis in pancreaticcancer: A call for new clinical approaches
-
Tuveson DA, Neoptolemos JP (2012) Understanding metastasis in pancreaticcancer: a call for new clinical approaches. Cell 148 (1-2) : 21-23.
-
(2012)
Cell
, vol.148
, Issue.1-2
, pp. 21-23
-
-
Tuveson, D.A.1
Neoptolemos, J.P.2
-
53
-
-
80051700067
-
Pancreaticcancer
-
Vincent A, Herman J, Schulick R, Hruban RH, Goggins M (2011) Pancreaticcancer. Lancet 378 (9791) : 607-620.
-
(2011)
Lancet
, vol.378
, Issue.9791
, pp. 607-620
-
-
Vincent, A.1
Herman, J.2
Schulick, R.3
Hruban, R.H.4
Goggins, M.5
-
54
-
-
83355169753
-
Gemcitabine plus nabpaclitaxelis an active regimen in patients with advanced pancreatic cancer: A phase I/II trial
-
Von Hoff DD, Ramanathan RK, Borad MJ, Laheru DA, Smith LS, Wood TE, Korn RL, Desai N, Trieu V, Iglesias JL, Zhang H, Soon-Shiong P, Shi T, Rajeshkumar NV, Maitra A, Hidalgo M (2011) Gemcitabine plus nabpaclitaxelis an active regimen in patients with advanced pancreatic cancer:a phase I/II trial. J Clin Oncol 29 (34) : 4548-4554.
-
(2011)
J Clin Oncol
, vol.29
, Issue.34
, pp. 4548-4554
-
-
Von Hoff, D.D.1
Ramanathan, R.K.2
Borad, M.J.3
Laheru, D.A.4
Smith, L.S.5
Wood, T.E.6
Korn, R.L.7
Desai, N.8
Trieu, V.9
Iglesias, J.L.10
Zhang, H.11
Soon-Shiong, P.12
Shi, T.13
Rajeshkumar, N.V.14
Maitra, A.15
Hidalgo, M.16
-
55
-
-
77950505872
-
Nuclearfactor kappaB-activated monocytes contribute to pancreatic cancerprogression through the production of Shh
-
Yamasaki A, Kameda C, Xu R, Tanaka H, Tasaka T, Chikazawa N, Suzuki H, Morisaki T, Kubo M, Onishi H, Tanaka M, Katano M (2010) Nuclearfactor kappaB-activated monocytes contribute to pancreatic cancerprogression through the production of Shh. Cancer Immunol Immunother59 (5) : 675-686.
-
(2010)
Cancer Immunol Immunother
, vol.59
, Issue.5
, pp. 675-686
-
-
Yamasaki, A.1
Kameda, C.2
Xu, R.3
Tanaka, H.4
Tasaka, T.5
Chikazawa, N.6
Suzuki, H.7
Morisaki, T.8
Kubo, M.9
Onishi, H.10
Tanaka, M.11
Katano, M.12
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